Cardiac Rehabilitation and Secondary Prevention:

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Cardiac Rehabilitation and Secondary Prevention: Get Pumped Up About Heart Health Janice Anderson, RN, BSN, CCRP Manager, Cardiac Rehabilitation and Secondary Prevention Christiana Care Health System

Statistics Heart Disease remains the #1 cause of death in the United States. Coronary heart disease accounts for 1 in 7 deaths in the US, killing over 366,800 people a year. Approximately every 40 seconds, an American will have a heart attack. The estimated direct and indirect cost of heart disease in 2013 to 2014 (average annual) was $204.8 billion. American Heart Association (Science Operation Department)

Anatomy The heart is about the size of your fist and sits in your upper chest with your ribs surrounding it for protection. On either side of the heart is the lungs, spinal cord and at the bottom is the diaphragm. This upper cavity/area is called the thorax

Anatomy of Heart

Electrical Conduction

How the Heart Works

Circulation

Coronary Arteries

Who can participate in CR&SP? Recent Heart Attack Coronary Artery Bypass Surgery Heart Valve Repair/Replacement Heart Angioplasty/Stenting Heart or Heart-Lung Transplant Stable Angina Compensated Heart Failure Some commercial insurances recognize additional cardiac diagnoses

Angina Angina usually occurs when narrowed coronary arteries can t deliver enough oxygen-rich blood to the heart muscle. The arteries may be narrowed because of: Atherosclerosis. Blood clots. Spasms of the artery.

Angina Symptoms Chest discomfort. Chest tightness. Chest fullness. Chest burning. Chest pain. Chest squeezing or pressure. Indigestion. Shortness of breath. Pain felt in the neck, jaw, arms, shoulder or back. Extreme fatigue Cold sweat

Immediate Treatment of Angina 1. Stop what you are doing. Sit or lie down. Rest! 2. If your doctor has prescribed nitroglycerin, follow these steps: Place one nitroglycerin tablet (or one spray)under your tongue. Wait three to five minutes. If your angina does not go away five minutes after taking your first nitroglycerin, call 9-1-1for an ambulance to take you to the hospital, and put a second tablet (or spray) under your tongue. Wait three to five minutes. If you still have angina, place a third tablet(or spray) under your tongue. 3. If you do not use nitroglycerin and you have angina, call 9-1-1 immediately.

Myocardial Infarction (MI)

Rupture of Plaque

MI Evaluation Physical Assessment Blood Studies EKG

Typical Treatment for Coronary Blockage Thrombolytic therapy Percutaneous Coronary Intervention (PCI) Percutaneous Transluminal Coronary Angioplasty (PTCA) Stenting Coronary Artery Bypass Graft (CABG)

Coronary Stent

Coronary Artery Bypass Graft

Valve Stenosis & Regurgitation

Heart Valve Repair/Replacement

Heart Failure

Left Ventricular Assist Device

Cardiac Rehabilitation & Secondary Prevention

History of CR& SP 1930s 6 weeks of bedrest 1940s physical activity introduced 1950s 5 minutes of daily walking at 4 weeks post MI 1960s Inpatient cardiac rehabilitation programs started. 1970s outpatient monitored exercise 1980s CR evolved from just focusing on exercise to a comprehensive medical and lifestyle modification model. 1990s The first Clinical Practice Guidelines for Cardiac Rehabilitation broadened the scope of cardiac rehabilitation. Bethell HJ, Cardiac rehabilitation: from Hellerstein to the millennium. Int J Clin Pract, 2000;54:92-97. Wenger NK. Current status of cardiac rehabilitation. J Am Coll Cardiol. 2008;51:1619-1631 Ades P.A. Cardiac rehabilitation and secondary prevention of coronary heart disease. N Engl J Med. 2001; 345:892-902 Wenger NK, Froehlicher ES, Smith LK, et al. Cardiac Rehabilitation: Clinical Practice Guidelines. Rockville, MD: Agency for Health Care Policy and Research and the National Heart, Lung and Blood Institute; 1995

What is Cardiac Rehabilitation and Secondary Prevention? It is a patient-centered, comprehensive, multidisciplinary, secondary prevention program.

What is Secondary Prevention? Secondary prevention attempts to identify a disease at its earliest stage so that prompt and appropriate management can be initiated. Successful secondary prevention reduces the impact of the disease by managing it in the earliest stage

The Goals of CR&SP CR/SP provides empowerment to our patients to understand Heart Disease and what can be done to control it. Know your numbers Understand what those numbers mean CR/SP provides a safe, controlled atmosphere staffed with healthcare professionals. CR/SP helps patients optimize their physical abilities and improve quality of life.

Studies: 3 x Increased likelihood of readmission for CABG patients who do not attend CR&SP compared to those who do attend 46% 10-year relative risk reduction in allcause mortality due to participation in CR&SP following CABG Source: Pack QR, et al., Participation in Cardiac Rehabilitation and Survival After CABG Surgery, Circulation, 128, (2013):590-597; Clark, AM et al., HedbäckB, et al., Cardiac Rehabilitation After Coronary Artery Bypass Surgery, Journal of Cardiovascular Risk, 8, (2001): 153-158; Cardiovascular Roundtable interviews and analysis.

Studies: 25-31% reduction in hospital readmissions in those who participated in CR & SP 31% decreased number of days of rehospitalizations shown with participation in CR & SP following MI or CABG 45-47% reduction of all cause mortality following PCI Source: Humen D, et al. A Cost Analysis of Event Reduction Provided by a Comprehensive Cardiac Rehab Program. Can J Card. 2013;29.10:S156. Levin LA, Perk J, Hedback B. Cardiac rehabilitation-a cost analysis. J Intern Med 1991;3=230:427-34 Goel K, Lennon RJ, Tilbury RT, Squires RW, Thomas RJ. Impact of cardiac rehabilitation on mortality and cardiovascular events after percutaneous coronary intervention in the community. Circulation 2011; 123:2344-52

Medicare: Comparison of # Sessions 1 session 14% lower risk of death 12% lower risk of MI 12 sessions 22% lower risk of death 23% lower risk of MI 36 sessions 47% lower risk of death 31% lower risk of MI Hammill BG, Curtis LH, Schulman KA, Whellan DJ. Relationship Between Cardiac Rehabilitation and Long- Term Risks of Death and Myocardial Infarction Among Elderly Medicare Beneficiaries. Circulation. 121(2010); pp 63-70.

CR & SP: a Class 1A Treatment 56% AHA Get With the Guidelines found that nationally only 56% of eligible patients were referred to CR & SP prior to hospital discharge. Compared to other proven Class 1 therapies prior to discharge: 98% aspirin use 93% beta-blocker use 84% ACE inhibitor/arb use Source: Jolliffe JA, Rees K, Taylor RS, Thompson D, Oldridge N, Ebrahim S. Exercise-based rehabilitation for coronary heart disease. Cochrane Database Syst Rev. 2001; (1): CD001800. Smith SC. Risk reduction therapies for patients with coronary artery disease: A call for increased implementation. Am J Med. 1998; 194 (S1) : 23S-26S Brown TM, Hernandez AF, Bittner V, et al. Predictors of cardiac rehabilitation referral in coronary artery disease patients: findings from the American Heart Association s Get With The Guidelines Program. J Am Coll Cardiol. 2009; 54:515-521

The Phases of CR&SP Phase 1- in hospital Phase 2 - out-patient Phase 3 - maintenance

Overview of Inpatient CR&SP program Order sets include CR & SP consults for inpatient and outpatient programs. Inpatient staff provides the following services: Assess and assist with activity Evaluate need for discharge O2 support and for assistive devices with ambulation Provide patient/family with discharge instructions and education for safe activity guidelines Refer patient to outpatient CR

What to Expect from Outpatient CR&SP CR & SP is a supervised, monitored, individualized exercise program with integrated Secondary Prevention education and counseling. Provides case-management, allowing for interventions that may prevent rehospitalization and empowering patient to understand and manage their disease. Program is typically 3 days a week for 3 months (total 36 sessions). However, tailored to individual needs. American Association of Cardiovascular and Pulmonary Rehabilitation. Guidelines for Cardiac Rehabilitation and Secondary Prevention Programs, Fifth edition

Outpatient CR&SP Initial assessment Thorough H&P Medication Reconciliation, also done daily The Individual Treatment Plan (ITP) will address and follow Goals, Interventions, Education, Reassessments and Final Assessment for: Exercise Nutrition Psychosocial Other Core Measurements/Risk Factors (ie -DM, HTN, CHF) Orientation to exercise program Daily assessments (ie dysrhythmias, pain/symptoms, hemodynamics, weight, blood sugar, medications, etc.)

Outpatient CR&SP Education (incorporated throughout the program) Patient Education Packet Individual and group education provided and evaluated Family/Support persons encouraged to participate ITP reviewed at least monthly with Medical Director Communication with cardiologist as needed, but minimum is: Start of program Mid program Completion of program with data provided At completion of program: Post data obtained Individualized exercise prescription ITP reviewed with patient, discuss achievements and future goals

Outpatient CR&SP The exercise program is individualized to optimize functional capacity. Exercise Prescription follows most recent ACSM/AHA/AACVPR guidelines, tailoring the exercise program to enhance and progress all levels of physical abilities, in a safe manner. Frequency Intensity Time Type Volume Progression Strong focus on incorporating safe home/independent activity.

Benefits of CR&SP Components The benefits realized at CR & SP programs are a combination of all CR & SP components. Approximately half of the mortality reduction achieved by exercise-based cardiac rehabilitation can be attributed to reductions of major risk factors. Other factors may also contribute to the benefits of CR/SP: reduction in inflammation ischemic preconditioning improved endothelial function a more favorable fibrinolytic balance Taylor RS, Unal B, Critchley JA, et al. Mortality reductions in patients receiving exercise-based cardiac rehabilitation: how much can be attributed to cardiovascular risk factor improvements? Eur J Cardiovasc Prev Rehabil 2006; 13:369-74. Milani RV, Lavie C, Mehra MR. Reduction in C-reactive protein through cardiac rehabilitation and exercise training. J Am Coll Cardiol 2004;43:1056-61

Core Components of CR&SP Exercise Training Physical Assessment Nutrition Counseling Physical Activity Counseling Weight Management Psychosocial Management Blood Pressure Management Tobacco Cessation Diabetes Management Lipid Management

Physical assessment

Patient Assessment The first appointment is with a Registered Nurse (RN): History and Physical Review Medications Discover preferred method of learning Assess for learning barriers Together create goals and plans to achieve these goals RN Case Management throughout program: Daily assessment Assessing and reassessing educational needs Physician communication Teach patient how to take control of disease Understand how to self-assess, become aware of signs and symptoms and what to do.

Nutrition

Nutrition Counseling We review eating habits at the start of the program. Determine where changes can be made specific to risk factors (ie- Diabetes, Hypertension, Heart Failure, Kidney Disease) Reassess eating habits at end of program We provide Nutrition Classes taught by a Registered Dietician. Heart Healthy Nutrition Class monthly Heart Failure Nutrition Class monthly Nutrition topics are discussed in exercise room to generate conversation. Opportunity for 1:1 sessions with Registered Dietician

Weight Management and Body Mass Index BMI Classification 18.5 to 24.9 Normal weight 25 to 29.9 Overweight 30+ Obesity (including extreme obesity) 40+ Extreme obesity Being obese can: raise blood cholesterol and triglyceride levels. lower your good HDL cholesterol level. increase blood pressure. induce diabetes. In some people, diabetes makes other risk factors much worse. The danger of heart attack is especially high for these people. Obesity increases the risk for heart disease and stroke. But it harms more than just the heart and blood vessel system. It's also a major cause of gallstones, osteoarthritis and respiratory problems. American Heart Association

Weight Management We get some information when starting the program: Body Mass Index Waist Circumference Rate Your Plate Questionnaire We then set realistic and reasonable goals. Loss of 1-2 pounds a week Nutrition Counseling Establish a consistent exercise program We track progress by repeating these measurements at the end of the program

Blood Pressure Blood pressure is recorded as two numbers: Systolic blood pressure (the upper number) indicates how much pressure the blood is exerting against the artery walls when the heart beats. Diastolic blood pressure (the lower number) indicates how much pressure the blood is exerting against the artery walls while the heart is resting between beats. Hypertension BLOOD PRESSURE CATEGORY SYSTOLIC mm Hg (upper number) DIASTOLIC mm Hg (lower number) Hypotension NORMAL LESS THAN 120 and LESS THAN 80 ELEVATED 120 129 and LESS THAN 80 HIGH BLOOD PRESSURE (HYPERTENSION) STAGE 1 HIGH BLOOD PRESSURE (HYPERTENSION) STAGE 2 HYPERTENSIVE CRISIS (consult your doctor immediately) 130 139 or 80 89 140 OR HIGHER or 90 OR HIGHER HIGHER THAN 180 and/or HIGHER THAN 120

Blood Pressure Management Blood Pressure medication dosages are directed by physician B/Ps done daily Review Medications Education If taken consistently Education Provide education about high and low blood pressure Understand what the numbers mean. Communicate with Physician Too high or too low

What are Lipids Total Cholesterol- A person s total cholesterol score is calculated by adding their HDL and LDL cholesterol levels and 20 percent of their triglyceride level. Total cholesterol levels are considered in context with other risk factors, and treatment is recommended accordingly. HDL- High Density Lipoprotein(healthy)-Think of it as the healthy cholesterol, so higher levels are better. Experts believe HDL acts as a scavenger, carrying LDL cholesterol away from the arteries and back to the liver. There it s broken down and passed from the body. LDL- Low Density Lipoprotein(lousy)-Think of it as less desirable or even lousy cholesterol, because it contributes to fatty buildups in arteries Triglycerides-Triglycerides are the most common type of fat in the body; they store excess energy from your diet. A high triglyceride level combined with low HDL cholesterol or high LDL cholesterol is linked with fatty buildups in artery walls. This increases the risk of heart attack and stroke. American Heart Association

Lipid Management Cholesterol medication dosage is directed by physician Review Medications Education If taken consistently Education Review lipid levels pre and post Understand what the numbers mean What can be done to improve lipids

What is Diabetes Diabetes is a chronic disease that happens when the body can t make enough of the hormone insulin or can t properly use the insulin it has. Insulin helps the body digest sugar (glucose) that comes from food and drinks, which is then used for energy. Without enough insulin, glucose builds up in the body, which over time can damage your nerves, blood vessels, heart and kidneys. Type I Diabetes Type II Diabetes

Diabetes Management Diabetic medication and dosages are directed by physician Check blood sugars before and after exercise Education Blood sugar monitoring and frequency Signs and symptoms of hypoglycemia and hyperglycemia Medication Diet May refer to Registered Dietician Living with Diabetes Program at PMRI Communicate with family doctor or endocrinologist any concerns or abnormal results

Tobacco Cessation Smoking is the most preventable cause of premature death in the United States Almost one third of deaths from coronary heart disease are attributable to smoking and secondhand smoke Smoking decreases your tolerance for physical activity and increases the tendency for blood to clot. It decreases HDL (good) cholesterol. Risks increase greatly if you smoke and have a family history of heart disease. Smoking also creates a higher risk for peripheral artery disease and aortic aneurysm. It increases the risk of recurrent coronary heart disease after bypass surgery, too.

Tobacco Cessation Review smoking status and other tobacco products Determine Readiness to Quit Stage of Change Connect patient with a smoking cessation counselor Individual education and counseling provided Pharmacological support Assess progress and Stage of Change throughout the program

Psychosocial Management: Stress Stress is your body s response to change. The body reacts to it by releasing adrenaline (a hormone) that causes your breathing and heart rate to speed up, and your blood pressure to rise. These reactions help you deal with the situation the "fight or flight" response. The problems come when stress is constant (chronic) and your body remains in high gear, off and on, for days or weeks at a time. Chronic stress may cause an increase in heart rate and blood pressure. Not all stress is bad. Speaking to a group or watching a close football game can be stressful, but they can be fun, too. The key is to manage stress properly Stress may affect behaviors and factors that increase heart disease risk: high blood pressure and cholesterol levels, smoking, physical inactivity and overeating. American Heart Association

Psychosocial Management Quality of Life perception questionnaire Assess for depression Support Exercise room conversation provides support Stress Management class Connect with clinical psychologist If already in treatment, communicate with that healthcare provider Medication compliance Support Groups

Physical Activity Physical activity is defined as any bodily movement produced by skeletal muscles that requires energy expenditure. Physical inactivity has been identified as the fourth leading risk factor for global mortality causing an estimated 3.2 million deaths globally. The four main types of physical activity are: Aerobic- Makes your heart rate and respiratory rate increase, making your heart and lungs stronger over time. running, swimming, walking,biking, etc Muscle-strengthening- Improves strength, power and endurance of muscles Push-ups, sit-ups, weight lifting, stair climbing, etc Bone-strengthening with feet, legs or arms supporting body s weight, the muscles are pushed against the bones running, walking, lifting weights, etc Stretching- helps improve flexibility and ability to fully move joints Side stretches, yoga, etc World Health Organization National Institute of Health

Physical Activity Counseling History of recent activity levels What are individual activity needs Domestic Occupational Recreational We typically encourage gradual accumulation of 30-60 minutes a day, 5 times a week Education Guidelines for safe, effective exercise Exercise at home during program Exercise after graduation from program

Exercise Training Exercise is a type of physical activity that's planned and structured. Medically supervised, telemetry monitored, exercise program Individualized exercise prescription Frequency Intensity Time Type Volume Progression Warm up, Cooldown, Strength Training and Flexibility

Benefits of Exercise Improves blood circulation, which reduces the risk of heart disease Establishes good heart-healthy habits in children and counters the conditions (obesity, high blood pressure, poor cholesterol levels, poor lifestyle habits, etc.) that lead to heart attack and stroke later in life Reduces risk of developing CHD/CVD by 30-40 percent Reduced risk of stroke by 20 percent in moderately active people and by 27 percent in those who are highly active Improves blood cholesterol levels Prevents and manages high blood pressure Prevents bone loss Keeps weight under control Boosts energy level Helps manage stress Counters anxiety and depression Helps you fall asleep faster and sleep more soundly Increases muscle strength, increasing the ability to do other physical activities

Case Study: 66 yo black female PMH: Coronary stent-12 years PTA HTN ESRD Sleep Apnea Breast Ca Hyperparathyroidism of renal failure Vitamin D deficiency of renal failure Gout Event: Patient was receiving hemodialysis for ESRD for approximately one year. On renal transplant list, when 2 weeks PTA, she began experiencing chest tightness while being dialyzed. Symptoms prompted Cardiac Cath which revealed TVD. Patient had CABG x 3 with LIMA. Post-op course complicated with cardiac arrest in the OR and in the unit. Hospital readmission for Afib with RVR.

Case Study: Clinical Outcomes: Pre-Entry Post-Entry Goals Resting B/P: 154/70 120/62 6MWT (ft): 150 1050 METS from 6MWT: 1.22 2.52 Lipids: TC: 168 179 HDL: 33 51 LDL: 109 108 TG: 129 102 Weight-lbs: 160 147 (5-10% loss) Ht: 70 inches BMI: 22.9 21.03 (<25) Waist-inches: 36 33 (<35 F <40m) Psychosocial: lower=improved) 29 18 (worst=45, PHQ9: 20 6 (goal is < or=5) Behavior Outcomes: Smoking: 0 0 Dietary-Rate your Plate: good+>55) 43 56 (worst=23 Physical Activity-Met/Min/Week: 0 500 (350-500)

Summary: CR & SP is a program that looks at the entire patient, as a unique individual, to create a program that will promote increased physical abilities, quality of life, independence and confidence. CR & SP provides education and counseling by a diverse Healthcare population, with specific expertise, to ensure that the patient is aware of his/her risk factors and is provided with the tools to manage these risk factors. It is the role of CR & SP to empowered patients to understand and manage their disease in the earliest stage, to stop the progression of disease. Age should not be a barrier to participation. Both the younger and older population should be afforded the opportunity to receive the tools to manage their disease, return to a productive and satisfying life, limiting co-morbidity issues and impairment of life expectancy.