NCI-designated Cancer Centers & Colorectal Cancer Screening

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NCI-designated Cancer Centers & Colorectal Cancer Screening MD Anderson s Cancer Prevention & Control Platform Transforming Science into Actions to Realize the Promise of Prevention & Control The function of protecting and developing health must rank even above that of restoring it when it is impaired. Hippocrates Ernest Hawk, M.D., M.P.H. VP for Cancer Prevention T. Boone Pickens Distinguished Chair for Early Cancer Prevention Head, Division of Cancer Prevention & Population Sciences Director, Duncan Family institute Co-director, Cancer Prevention & Control Platform

MD Anderson s Mission To eliminate cancer in Texas, the nation and the world Research Clinical Care Individuals Education & Training Future generations Cancer Prevention & Control Community

Colorectal Cancer Screening in Texas Texas Ranks 41 st in the Percentage of 50+ Meeting CRC Screening Rec s: 62.7% Texas 1 2/3 4/5N 6/5S 7 8 9/10 11 3.6% 4.0% 2.9% 4.6% 4.5% 2.9% 4.0% 4.6% 1.7% Colorectal Cancer Stage at Diagnosis by Health Service Region, 2008-2012 In-Situ Localized Regional 34.8% 33.9% 34.0% 38.0% 32.5% 38.0% 34.5% 37.2% 36.2% 30.7% 33.5% 32.0% 30.4% 30.3% 31.2% 28.2% 28.8% 29.5% 19.1% 19.4% 19.2% 19.1% 17.8% 20.6% 17.6% 19.5% 19.4% 11.8% 8.0% 11.6% 10.3% 13.5% 9.3% 11.2% 10.6% 15.5% Source:Prepared by the Texas Department of State Health Services, Cancer Epidemiologyand Surveillance Branch, Texas Cancer ACS: CRC Facts & Figures, 2017-2019; NCI & CDC State Cancer Profiles

Figure from Zauber, AG, Meester, RG, Fedewa, S et al. (2016, May). The National Colorectal Cancer Roundtable Campaign to Screen 80% for Colorectal Cancer by 2018: Mapping Progress by State to Focus Screening Effort. Poster presented at the Digestive Disease Week conference, San Diego, CA.

Translational Research Phases Resulting in Evidence-Based Clinical & Public Health Actions to Drive Impactful Cancer Control (Based in part on a drug-approval paradigm) White paper The 2016 AACR Cancer Prevention Summit; Manuscript submitted, Cancer Prev Res 2017

MD Anderson s Cancer Control Platform Develop and deliver comprehensive evidence-based strategies (PES) in cancer prevention, screening, early detection and survivorship to achieve a measurable and lasting reduction in the cancer burden, especially among the underserved. Actions Policies Education public & professional Services beyond MD Anderson s walls Expertise Gov l Relations Health Policy Public Education Professional Education D&I of Community-based Services Tobacco cessation Nutrition Physical activity Cancer screening Vaccination Partners UT Sister Institutions American Cancer Society Harris Health & LBJ Hospital FQHCs & CHCs TX Dept State Health Svsc Cancer Alliance of Texas Texas Medical Association Local & nat l health coalitions Funding Grants CPRIT Medicaid 1115 Waiver Institutional Philanthropic Corporate Individual

MD Anderson CRC Group Education Program Delivered by Community Relations & Education Department Colorectal Cancer: Reduce Your Risk Educates on CRC screening exams, risk factors, preventive behaviors Presented in 1-3 sessions Colorectal cancer 101 Healthy cooking demonstration Physical activity class Also available in English, Spanish & Vietnamese Conducted 39 programs reaching 1,134 people in FY17 Outcome: 67% report they intend to get a screening test as result of program Cost: $2 per participant, not incl. staff salaries Attendance: 73% Hispanic, 20% Asian, 2% African American; 65% uninsured Information & data provided by Stephanie Kim, Director; Community Relations & Education, Strategic Communications, MD Anderson

MD Anderson Program to Increase CRC Screening Services for Poor & Underserved Communities Program Components Partnerships: FQHCs & CHCs Patient education - culturally- & linguistically-tailored EHR reminder systems Clinician/staff education - to identify eligible pts. based on clinical & financial criteria Standing orders Take-home FIT test (results to clinic & MDACC) Patient navigation Referral to community endoscopists for diagnosis Funded thru Medicaid Waiver & CPRIT prev. grant Medicaid Health Plan (Community Health Choice credentialing, claims) as Third Party Administrator Project Staff Navigation Responsibilities Partner with ACS team to deliver pt. education Track FITs distributed & returned Navigate pt referrals for evaluation of + tests to community GIs for colonoscopy/polyp removal F/U pts diagnosed with polyps to arrange further assessment Navigate pts diagnosed with cancer to treatment Data analysis & reporting to funding agency Provide audit & feedback to clinics Eliminates financial barriers by covering cost of endoscopy & polypectomy

MD Anderson CRC Screening Partner Map

Project & Funding Source Colorectal Cancer Screening - Metrics to Date Navigation & practice change expanded into 20 clinic systems with 68 sites FIT-FLU (CPRIT-funded Project) 1115Waiver Project (43 sites) Reporting Dates 2011-2012 10/01/2013 9/20/2017 Total FITs Distributed ACT (CPRIT-funded Project 25 sites) 02/22/2016 09/20/2017 Total 2011-2017 900 17,473 3,999 22,372 Total Returned 576 (64%) 11,996 (68.7%) 2562 (64%) 15,134 (67.6%) Number Positive 22 (3.8%) 722 (6.0%) 194 (7.6%) 938 (6.2%) Colonoscopies Completed Pts with Polyps Removed Cancers Diagnosed 20 460 113 593 8 264 42 314 1 35 7 43

Challenges in Providing CRC Screening Services to Rural & Underserved Populations in Texas Cultural misalignment Transportation concerns Lack of support for CRC screening in the uninsured CPRIT funds screening, but not diagnostic or treatment services Few specialists & facilities equipped to perform endoscopies Specialists may not accept reimbursement rates Limited financial assistance for treating uninsured & low-income patients No financial assistance for unauthorized patients

Project ECHO: Telementoring, not Telemedicine (Leads -Ellen Baker, MD & Melissa Lopez, MSc) Connects MD Anderson experts with community providers serving underserved populations to promote skill development & raise self-efficacy in novel areas of medical practice Weekly/monthly videoconferences (45 min cases, 15 min didactic) Community providers present cases (e.g., patient histories, lab results, treatment plans, challenges) Feedback and guidance provided by MD Anderson s (or partners ) specialists Community providers & specialists forge stronger working relationships toward the shared goal of high-quality care delivery

MD Anderson s ECHO Projects Launched Expanding Exploring Survivorship Palliative Care Pathology Cervical Cancer Prevention- Texas-Mexico Border ECHO Zambia ECHO Mozambique ECHO Latin America ECHO Tobacco Cessation Tobacco Cessation Latin America Pharmacy in Zambia Radiation therapy Dr. Sriram Yennu Palliative Care Dr. Lewis Foxhall Survivorship Dr. Irene Tami-Maury Tobacco Cessation Dr. Anuja Jhingran Radiation Therapy Dr. Kathleen Schmeler Cervical Screening Dr. Janice Blalock Tobacco Cessation Dr. Mary Edgerton Pathology Dr. Shon Black Breast Surg. Oncology Dr. Oliver Bogler GAP

Suggestions for ACS/NCI/CDC to Promote CRC Screening in NCI-designated Cancer Centers Clearly define and communicate the difference between D&I research vs. D&I actions (control) Strengthen the current Community Outreach & Engagement section of the CCSG core grant Clarify criteria (e.g., focus on disparities of all types; integrated actions, not research alone) Outline best practices (e.g., partnerships with FQHCs) Establish metrics/expectations Work with CDC and/or other federal agencies to fund such actions (transitioning CCSG to a collaborative, cross-agency program) Advocate for: More funding of cancer control, not just cancer research A national cancer control plan, establishing clear national goals and priorities across administrations Coverage for cancer screening (incl. CRC) for all, not just those with insurance Commercial EHR vendors to build patient/provider reminder systems into their products Develop and disseminate patient/provider screening decision-support materials