Advanced Lung Disease Conference

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Advanced Lung Disease Conference Novel Therapies and www.dfcon.com Controversies www.bcm.edu/surgical-conference Scientific Program December 7-8 Four Seasons Hotel Houston www.dfcon.com #DFCon17 www.facebook.com/dfcon

Course-Directors Gabriel Loor, MD Cardiothoracic Transplant and Circulatory Support Co-Directors Amit D. Parulekar, MD, MS Pulmonary and Critical Care Medicine David J. Sugarbaker, MD General Thoracic Surgery Prasad Manian, MBBS, MD Pulmonary and Critical Care Medicine Kenneth McCurry, MD Cleveland Clinic Ramsey Hachem, MD Washington University School of Medicine in St. Louis

PROGRAM OVERVIEW The Advanced Lung Disease: Novel Therapies and Controversies Conference will have engaging state-of-the-art multidisciplinary lectures focused on the causes diagnosis, prevention, and treatment of diseases affecting the lungs, including cystic fibrosis, COPD, Interstitial Lung Disease, pulmonary hypertension and adult congenital heart diseases. The course will also feature panel sessions to provide clinicians the opportunity to discuss specific treatment challenges, the role of the caregivers, transplant coordinators and logistics of transplantation and methods that will be useful in their practices. Advanced lung diseases affects a large part of the population and contributes significantly to morbidity and mortality. Novel therapies for diseases such as cystic fibrosis, COPD, Interstitial Lung Disease, pulmonary hypertension and adult congenital heart diseases have given patients a chance at a new and healthier life. Transplantation is a major part of the innovation for providing these patients a new lease on life, but there are many steps and considerations along the way that can add to quality life years. The conference seeks to provide practitioners, trainees, patients and associated staff with a look at the horizon of advanced lung therapies. Novel therapies such as ex vivo lung perfusion, airway stenting, biopsies, gene therapy, stem cells, bronchial valves and lung volume reduction therapy will be discussed. Break out sessions will discuss the role of the caregivers, transplant coordinators and logistics of transplantation.

SPONSORED BY Baylor St. Luke s Medical Center PLANNING COMMITTEE Ronnetta Eaton Scott Holmes Rebecca Means Rizwan Moton Lauren Samuels Libby Schwenke Susan Ressler

Four Seasons Hotel Houston 1300 Lamar Street Houston, TX 77010 United States (713) 650-1300

CME INFORMATION The course will offer 14.50 AMA PRA Category 1 Credits for physicians. LEARNING OBJECTIVES Describe the background and evolution of individual pulmonary diseases, the evolving management strategies, and controversies. Understand the work up for lung or heart lung transplantation and the role of extracorporeal membrane oxygenation in acute exacerbations or as an adjunct to transplantation. Stress detailed operative descriptions of each presenter s approaches to pulmonary care. Provide valuable insight through video education and interactive panels of pulmonologists. TARGET AUDIENCE This activity is designed for pulmonologists, transplant pulmonologists, respiratory therapists, internal medicine physicians, thoracic surgeons, critical care specialists, general surgeons, nurses, residents, fellows, and advanced practice providers who are interested in optimizing their pulmonary outcomes.

Friday, December 7, 2018 7:30 Registration/Continental Breakfast 7:50 Welcome / Announcements / Opening Remarks Session I Advanced Lung Disease I: Obstructive Airway Disease Nicola Hanania, MD 8:00-8:20 COPD Classification, Phenotypes, and Risk Assessment Prasad Manian, MD 8:20 8:40 Pharmacotherapy in COPD Amir Sharafkaneh, MD 8:40 9:00 Asthma Classification and Management Amit Parulekar, MD 9:00 9:20 Revisiting Severe Asthma: Phenotypes, Biomarkers and Novel Targets of Therapy Nicola Hanania, MD 9:20 09:40 Panel Discussion 09:40 9:50 Break Session II Advanced Lung Disease II: Cystic Fibrosis and Interstitial Lung Disease Tara Barto, MD and Joseph Lasky, MD 9:50-10:10 Multidisciplinary Approach to Cystic Fibrosis Care Tara Barto, MD 10:10 10:30 Novel Therapies for Cystic Fibrosis Peter W. Hiatt, MD 10:30 10:50 Classification and Diagnosis of Diffuse Parenchymal Lung Disease Namrata Patel, MD 10:50 11:10 ILD Exacerbations and When to Refer for Lung Transplantation Jigna Zatakia, DO 11:10 11:30 Pharmacotherapy and Other Novel Therapies for IPF Joseph Lasky, MD 11:30 11:50 Panel Discussion

11:50 12:50 Lunch Keynote The Role of the Immune System in Lung Transplantation: Towards Improved Long-Term Results - Ramsey Hachem, MD 12:50-1:00 Break Session III ECMO for Respiratory Failure Subhasis Chatterjee, MD 1:00 1:20 ECMO as a Rescue Therapy for Severe Hypoxemic Respiratory Failure Pat Herlihy, MD 1:20 1:40 ECMO Technique and Pitfalls Aladdein Mattar, MD 1:40 2:00 Bedside Troubleshooting for ECMO Subhasis Chatterjee, MD 2:00 2:20 ECMO as Bridge to Transplant Matthew Hartwig, MD 2:20 2:40 Panel Discussion 2:40 2:50 Break Session IV Donor Logistics for Lung Transplantation - Macon Woodard, MHSM, BSN, RN 2:50 3:10 Donor Lung Allocation and Logistics Patrick Wood, MD 3:10 3:30 Donor and Recipient Team Transportation Roger Woolsey 3:30 3:50 Donor Lung Recruitment and Optimization Rajat Walia, MD 3:50 4:10 Breathing Lung transplantation: Lessons Learned and Future Implications Gabriel Loor, MD 4:10 4:30 Wrap Up / Final Comments 4:30 Adjourn

Saturday, December 8, 2018 7:30 Registration / Continental Breakfast 7:50 Welcome / Announcements / Opening Remarks Session I Pulmonary Hypertension Ajith Nair, MD 8:00 8:20 Evaluation and Classification of Pulmonary Arterial Hypertension Roham Zamanian, MD 8:20 8:40 Pharmacotherapy for Pulmonary Hypertension Ajith Nair, MD 8:40 9:00 Assessment and Treatment of the Failing Right Heart and Considerations for Transplant Referral Ziad Taimeh, MD 9:00 9:20 Panel Discussion 9:20 9:30 Break Session II Medical Aspects of Lung Transplantation Amit Parulekar, MD 9:30 9:50 Indications for Transplant Referral and Listing Goutham Dronavalli, MD 9:50 10:10 Postoperative Management of Lung Transplant Patients Amit Parulekar, MD 10:10 10:30 The Role of Esophageal Pathology in End-Stage Lung Disease and Lung Transplantation Lara Schaheen, MD 10:30 10:40 Break 10:40 11:00 Detection, Classification and Management of Rejection Christina Kao, MD 11:00 11:20 Post-Operative Outcomes and Risk Factors Gloria Li, MD 11:20 11:40 Panel Discussion

11:40 12:40 Lunch Keynote Safe Expansion of the Donor Pool and Recipient Indications: Lessons Learned from the Cleveland Clinic Experience Kenneth McCurry, MD 12:40 12:50 Break Session III Surgical Aspects of Lung Transplantation Gabriel Loor, MD 12:50 1:10 Donor and Recipient Surgical Procedures 101 Gabriel Loor, MD 1:10 1:30 Controversies in Lung Transplant: Single Versus Bilateral Lung Transplantation, On Pump Versus Off Pump Matthew Hartwig, MD 1:30 1:50 Complex Scenarios: Adjunctive Cardiac Procedures and Redo Lung Transplant - Kenneth McCurry MD 1:50 2:10 En Bloc Transplant Procedures: Bronchial Artery Revascularization and Heart-Lung Transplantation Gosta Pettersson, MD 2:10 2:30 Panel Discussion 2:30 2:45 Wrap up / Final Comments

Conference Faculty Tara Barto, MD Michael Beers, MD University of Pennsylvania, Perelman School of Medicine Subhasis Chatterjee, MD Goutham Dronavalli, MBBS Ramsey Hachem, MD Washington University School of Medicine, St. Louis Nicola Hanania, MD, MS Matthew Hartwig, MD Duke University School of Medicine Pat Herlihy, MD Peter Hiatt, MD Texas Children s Hospital Christina Kao, MD Joseph Lasky, MD Tulane University Gloria Li, MD Gabriel Loor, MD Prasad Manian, MBBS, MD Kenneth McCurry, MD Cleveland Clinic Ajith Nair, MD Amit Parulekar, MD, MS Gosta Pettersson, MD, PhD Cleveland Clinic Lara Schaheen, MD Amir Sharafkaneh, MD, PhD Ziad Taimeh, MD Rajat Walia, MD Norton Thoracic Institute St. Joseph s Hospital and Medical Center R. Patrick Wood, MD Baylor St. Luke s Medical Center Macon Woodard, MHSM, BSN, RN Baylor St. Luke s Medical Center Roger Woolsey Roham Zamanian, MD Stanford University Medical Center Jigna Zatakia, DO Aladdein Mattar, MD