WPW syndrome and AVRT

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WPW syndrome and AVRT Myung-Yong Lee, MD, PhD Division of Cardiology Department of Internal Medicine School of Medicine Dankook University, Cheonan, Korea

Supraventricular tachycardia (SVT) Paroxysmal supraventricular tachycardia (PSVT) Atrial fibrillation (AF) Sinus tachycardia Physiologic sinus tachycardia Inappropriate sinus tachycardia Atrial tachycardia (AT) Focal AT Sinus node reentry tachycardia Multifocal atrial tachycardia (MAT) Atrial flutter Cavotricuspid isthmus dependent atrial flutter: typical Cavotricuspid isthmus dependent atrial flutter: reverse typical Atypical or non cavotricuspid isthmus dependent atrial flutter Junctional tachycardia Atrioventricular nodal reentrant tachycardia (AVNRT) Typical AVNRT Atypical AVNRT Accessory pathway Manifest accessory pathways Concealed accessory pathway Pre-excitation pattern Asymptomatic pre-excitation (isolated pre-excitation) Wolff-Parkinson-White syndrome Atrioventricular reentrant tachycardia (AVRT) Orthodromic AVRT Antidromic AVRT Permanent form of junctional reciprocating tachycardia An umbrella term used to describe tachycardias (atrial and/or ventricular rates in excess of 100 bpm at rest), the mechanism of which involves tissue from the His bundle or above. A clinical syndrome characterized by the presence of a regular and rapid tachycardia of abrupt onset and termination. PSVT represents a subset of SVT. Richard L. Page et al. Circulation. 2016;133:e506-e574

Supraventricular tachycardia (SVT) Paroxysmal supraventricular tachycardia (PSVT) An umbrella term used to describe tachycardias (atrial and/or ventricular rates in excess of 100 bpm at rest), the mechanism of which involves tissue from the His bundle or above. A clinical syndrome characterized by the presence of a regular and rapid tachycardia of abrupt onset and termination. PSVT represents a subset of SVT. Atrial fibrillation (AF) Sinus tachycardia Physiologic sinus tachycardia Inappropriate sinus tachycardia Atrial tachycardia (AT) Focal AT Sinus node reentry tachycardia Multifocal atrial tachycardia (MAT) Atrial flutter Cavotricuspid isthmus dependent atrial flutter: typical Cavotricuspid isthmus dependent atrial flutter: reverse typical Atypical or non cavotricuspid isthmus dependent atrial flutter Junctional tachycardia Atrioventricular nodal reentrant tachycardia (AVNRT) Typical AVNRT Atypical AVNRT Accessory pathway Manifest accessory pathways Concealed accessory pathway Pre-excitation pattern Asymptomatic pre-excitation (isolated pre-excitation) Wolff-Parkinson-White syndrome Atrioventricular reentrant tachycardia (AVRT) Orthodromic AVRT Antidromic AVRT Permanent form of junctional reciprocating tachycardia (PJRT) Richard L. Page et al. Circulation. 2016;133:e506-e574

Accessory Pathways Atrium and ventricle: insulated by cardiac skeleton Normally, AV node is the only electrical connection between A and V Gray's Anatomy. Published January 1, 2008 Copyright from The Royal College of Surgeons of England

Accessory Pathways and Reentry WPW syndrome Sinus rhythm Orthodromic Antidromic SAN SAN SAN AVN AVN AVN Concealed AP PJRT Mahaim SAN SAN SAN AVN AVN AVN

Accessory Pathways and Reentry WPW syndrome Sinus rhythm SAN AVN

Accessory Pathways and Reentry WPW syndrome Antidromic SAN AVN

Accessory Pathways and Reentry WPW syndrome Orthodromic SAN AVN

Differential Diagnosis of Narrow QRS tachycardia QRS duration Regularity P waves RP interval Richard L. Page et al. Circulation. 2016;133:e506-e574

Typical AVNRT Pseudo r in V1 Pseudo S in the inferior leads 2015 KHRS_ARC_3_DKUH_#1 10

AVRT with Retrograde P RP interval 100 msec

ECG algorithm for AP localization J Cardiovasc Electrophysiol 1998;9:2

Accessory Pathway: Left Free Wall

Accessory Pathway: Septal

Accessory Pathway: Right Free Wall

Differentiation of PSVT in EPS Baseline Observations and Tachycardia Features Prevalence (%) Positive Predictive Value (%) AVNRT ORT AT Pre-excitation present during sinus rhythm 15 10 86 3 Extranodal response to para-hisian pacing 18 17 83 0 VA block cycle length > 600 msec at baseline 11 41 5 55 Septal VA interval > 70 msec 53 17 59 24 Eccentric atrial activation 31 0 76 24 Spontaneous AV block during tachycardia 10 60 0 40 Spontaneous termination with AV block 28 66 34 0 Development of LBBB 12 4 92 4 Increase in VA interval > 20 msec with BBB 7 0 100 0

Eccentric Atrial Activation Distal CS Distal CS His His HRA Proximal CS RV HRA RV Proximal CS 2015 KHRS_ARC_3_DKUH_#3 17

Induction with AH Jump and Concentric Atrial Activation

His Synchronious Ventricular Extrastimulation (V reset) 406 msec 382 msec

His Synchronious Ventricular Extrastimulation (V reset) 20 msec

PPI-TCL: AVRT 510 msec 442 msec PPI-TCL = 68 (<115)

PPI-TCL: AVNRT 521 msec 337 msec PPI-TCL = 184 ( 115)

Coumel s law Positive Prediction Value: 100% in ORT Ipsilateral BBB produces prolonged TCL Narrrow QRS Ipsilateral BBB Contralateral BBB SAN SAN SAN AVN AVN AVN

Coumel s law 294 msec 251 msec 243 msec

294 msec 251 msec 243 msec SAN SAN SAN AVN AVN AVN +43 ms Ipsilateral BBB Narrrow QRS Contralateral BBB TCL: 294 ms TCL: 251 ms

Acute treatment of orthodromic AVRT Richard L. Page et al. Circulation. 2016;133:e506-e574

Acute treatment of orthodromic AVRT Richard L. Page et al. Circulation. 2016;133:e506-e574

Ongoing management of orthodromic AVRT Richard L. Page et al. Circulation. 2016;133:e506-e574

Success and Complication Rate for Ablation of AVRT Acute success rate: 93% Recurrent Rate: 8% Major Complications Overall 2.8% PPM 0.3% Death 0.1% Tamponade 0.4% Spector P, et al. Am J Cardiol. 2009;104:671 7. Calkins H, et al. Circulation. 1999;99:262 70.

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