Comprehensive Surgical Approaches to the Skull Base:

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The University of Texas MD Anderson Cancer Center Comprehensive Surgical Approaches to the Skull Base: Indications for Open and Endoscopic Approaches in the Management of Complex Benign and Malignant Pathology Sept. 26-30, 2018 The University of Texas MD Anderson Cancer Center Microsurgical and Endoscopic Center for Clinical Applications Laboratory Baylor College of Medicine DeBakey Building 6450 E. Cullen Street Houston, Texas

Comprehensive Surgical Approaches to the Skull Base GOAL The goal of this activity is to improve the understanding regarding relative indication for open and endoscopic skull base approaches, improve anatomic understanding of the full spectrum of open and endoscopic skull base approaches needed to treat skull base pathology, improve understanding regarding the indications and goals for surgery in the management of skull base malignancies. This activity will include pre-recorded lectures on temporal bone and anterior/ anterolateral skull base. These lectures will be available for participants to review before the activity, to allow for optimal time in the cadaver labs. The live activity will consist of four and a half days of short didactic lectures (tumor boards) followed by a hands-on workshop. The workshop will allow participants to gain experience with dissections and watch demonstrations by experts in skull base tumors. Educational Objectives After attending the conference, participants should be able to: Evaluate the role of surgery within the context of multimodality care in the management of skull base malignancies. Assess the relative indications for endoscopic and open skull base approaches in the management of complex skull base pathology and implement them into practice. Understand the anatomical basis of various open and endoscopic skull base approaches in the management of malignant tumors of the anterior and anterolateral skull base. Target audience Neurosurgeons, head and neck surgeons, otolaryngologists, rhinologists, otologists and neuro-otologists. Educational methods Lecture Case Study Panel Discussion Hands-on Workshop Skills-Based Training Skills This course has been certified as a Level 2 course according to the AMA Guidelines on New Procedures and Skills Courses. Level 2 Course: Verification of satisfactory completion of course objectives: the physician satisfactorily met all specified learning objectives. Accreditation/ Credit Designation The University of Texas MD Anderson Cancer Center is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The University of Texas MD Anderson Cancer Center designates this live activity for a maximum of 38.50 AMA PRA Category 1 Credits TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. CME Certificates and Attendance Verification Certificates Certificates awarding AMA PRA Category 1 Credit or certificates documenting attendance will be distributed to participants when an individual departs the conference. To obtain a CME certificate, physicians must submit a completed evaluation questionnaire and a CME Verification Form. Upon request, a record of attendance (certificate) will be provided on-site to other health care professionals for requesting credits in accordance with state nursing boards, specialty societies, or other professional associations. Evaluation The activity evaluation will provide participants with the opportunity to comment on the value of the activity content to their practice decisions, performance improvement activities, or possible impact on patient health status. Participants will also have the opportunity to comment on any perceived commercial bias in the presentations as well as to identify future educational topics.

Comprehensive Surgical Approaches to the Skull Base Program Committee Shaan M. Raza, M.D., FAANS Assistant Professor of Neurosurgery and Franco DeMonte, M.D., FRCS(C), FACS, FAANS (Former President, North American Skull Base Society) Professor of Neurosurgery and Head and Neck Surgery Ehab Hanna, M.D., FACS (Former President, North American Skull Base Society) Professor of and Neurosurgery Paul W. Gidley, M.D., FACS Professor of and Neurosurgery Jennifer Everts Program Coordinator, Neurosurgery Kristi English CHCP Manager, CME/Conference Management MD Anderson Course Faculty Shaan M. Raza, M.D., FAANS Neurosurgery @DrShaanRaza Franco DeMonte, M.D., FRCS(C), FACS, FAANS Neurosurgery Ehab Hanna, M.D., FACS Paul W. Gidley, M.D., FACS @PaulGidleyMD Michael E. Kupferman, M.D., FACS @mekupferman Shirley Y. Su, M.B.B.S., FRACS @DrShirleySu Marc-Elie Nader, M.D., FRCS(C) @DrMarcElieNader Richard C. Allen, M.D., Ph.D. @RichardAllenMD Matthew Hanasono, M.D., FACS Plastic Surgery Peirong Yu, M.D., FACS Plastic Surgery Temporal Bone Module Translabrynthine Transcohclear Extended Middle Fossa Combined Petrosal Temporal Bone Resection for Cancer Hearing Rehabilitation Facial Nerve Rehabilitation Pre-Recorded Lectures The lectures below will be available to course participants before the conference via a secure web link. Anterior/Anterolateral Skull Base Module Zone I (Anterior Skull Base/Sinonasal Cavity/Paranasal Sinuses) Open Approaches - Bifrontal/Transbasal Craniotomy - Transfacial Approaches: Lateral Rhinotomy and Weber-Fergusson Endoscopic Approaches - Endoscopic transcribriform Zone II (Orbit/Middle Fossa (Cavernous Sinus/Sellar/Parasellar)/Infratemporal Fossa) Open Approaches - Transconjunctival/Transpalpeberal - Orbitozygomatic Craniotomy - Subtemporal-Infratemporal Fossa - Mandibular Swing Endoscopic - Endoscopic endonasal transpterygoid - Endoscopic endonasal transtubercular/transplanum Zone III (Posterior Fossa) Endoscopic - Endoscopic endonasal transclival Open - Maxillary Swing

Course Schedule Temporal Bone Module 11 a.m. 12 p.m. Wednesday, Sept. 26 Onsite registration Welcome Shaan Raza 1:45 p.m. 2 to 6 p.m. Hearing Rehabilitation Therapy Marc-Elie Nader Participant Dissection: Jugular Foramen (Fisch C Approach) Instructor Demonstration: Transcochlear Approach 12:15 p.m. With Lunch 1 to 5 p.m. 7 p.m. Tumor Board for Vestibular Schwannomas Participant Dissection: Translabyrinthine Approach Instructor Demonstration: Middle Fossa Approach Course dinner Thursday, Sept. 27 Anterior/Anterolateral Skull Base Approaches Module 7:30 a.m. 8 a.m. 8:15 a.m. Friday, Sept. 28 Breakfast and onsite registration Welcome Shaan Raza Multidisciplinary Tumor Board Shirley Su, Richard Allen 7 a.m. 8 a.m. 9 a.m. to 1 p.m. 1:15 p.m. With Lunch Breakfast Tumor Board for Temporal Bone Cancers Participant Dissection: Lateral Temporal Bone Resection for Malignancy Instructor Demonstration: Subtotal Temporal Bone Resection Soft Tissue Reconstruction Considerations for Lateral Skull Base Cancers Matthew Hanasono, Peirong Yu 9:15 a.m. to 1 p.m. 1:15 p.m. With Lunch Participant Dissection: Zone I Approaches: (Open or Endoscopic) Instructor Demonstration: Transbasal Approach and Lateral Rhinotomy Instructor Demonstration: Endoscopic Transcribriform Approach Shirley Su Soft Tissue Reconstruction for Open Skull Base Resections Matthew Hanasono, Peirong Yu

Course Schedule Anterior/Anterolateral Skull Base Approaches Module Friday, Sept. 28 1 p.m. With Lunch Tumor Board (Review of cases submitted by participants) Shirley Su, Radiation Oncology faculty, Medical Oncology faculty 1:45 p.m. 2 to 6 p.m. Reconstruction Considerations for Endoscopic Skull Base Resections Shaan Raza Participant Dissection: Zone I Approaches to Clivus (Open and Endoscopic) Instructor Demonstration: Endoscopic Transclival Instructor Demonstration: Endoscopic Maxillary Swing Shirley Su 2 to 6 p.m. 7 a.m. Cadaver Dissection: Zone II Approach (Open or Endoscopic) Prosection: Endoscopic Transpterygoid Shirley Su Sunday, Sept. 30 Breakfast 7:30 p.m. Course Dinner 8 a.m. to 12 p.m. Free Dissection Period Saturday, Sept. 29 7:30 a.m. Breakfast 8 a.m. Tumor Board (Emphasis on Multimodality Management) Shirley Su, Radiation Oncology faculty, Medical Oncology faculty 9 a.m. to 1 p.m. Participant Dissection: Zone II Approaches (Open or Endoscopic) Instructor Demonstration: Endoscopic Transpterygoid Instructor Demonstration: Subtemporal Infratemporal Fossa Shirley Su

Comprehensive Surgical Approaches to the Skull Base About the MECCA Lab Registration The course will take place in the David C. Nicholson Microsurgical and Endoscopic Center for Clinical Applications Laboratory, a multidisciplinary state-of-the-art cadaveric surgical lab for education, training and research. It features 17 integrated stations with LED surgical lights and in-line cameras. Bidirectional video feeds and multiple 3D screens create a modern surgical operatory setting and allow the feed from a central workstation to be easily broadcast to the entire room. The lab is housed in Baylor College of Medicine s DeBakey Building and co-managed by MD Anderson and Baylor. On-site registration opens at 11 a.m. on Wednesday, Sept. 26, 2018, at Baylor College of Medicine, MECCA Lab, 1 Baylor Plaza, Houston, Texas. The conference will begin at noon on Wednesday, Sept. 26, and will adjourn on Sunday, Sept. 30, 2018, at 12 p.m. Advanced registration is encouraged as space and materials are limited. Registration Fees Temporal Bone Module: Early Registration Fee...$750.00 Late Registration...$1,000.00 14 Participants Max/ 1 Registration per Fully Injected Cadaver Head Anterior/Anterolateral Skull Base Module: Early Registration Fee...$1,250.00 Late Registration...$1,500.00 24 Participants Max/ 2 Participants per Fully Injected Cadaver Head Early registration: Before Aug. 1, 2018. Late registration: After Aug. 1, 2018. Register online: www.mdanderson.org/conferences. Register by mail or fax: See registration at the end of this brochure for instructions. We accept the following forms of payment: Check (payable through U.S. banks only) Money order Credit cards (MasterCard, Visa and American Express) Cash (on-site registration only) Scenes from past training courses in the MECCA Lab. If you register online, a receipt/confirmation letter will be automatically emailed to the email address you list on the registration form. If you register by fax or mail, a receipt/ confirmation letter will be sent to you within 10 working days of the receipt of your fee.

Comprehensive Surgical Approaches to the Skull Base Registration Refund/Cancellation Policy The registration fee, minus a $50 administrative handling fee, is refundable if a written request is received on or before Aug., 24, 2018. No refunds will be granted after that date. The request for a registration refund must include the tax identification number of the company or institution if registration was paid by a company or institution check. For additional information, contact CME/Conference Management at 713-792-2223 or toll free at 866-849-5866. The Department of CME/Conference Management reserves the right to cancel activities prior to the scheduled date, if low enrollment or other circumstances make it necessary. Each registrant will be notified by mail, email, or at the phone or fax numbers given on the registration form. In case of activity cancellation, the liability of the Department of CME/Conference Management is limited to the registration fee. CME/Conference Management will refund the full registration fee. The Department of CME/Conference Management reserves the right to limit the number of participants in a program and is not responsible for any expenses incurred by an individual whose registration is not confirmed and for whom space is not available. Please check the website www.mdanderson.org/conferences. Special Assistance Contact the Department of CME/Conference Management at 713-792-2223 or toll free at 866-849-5866 if you have any special dietary or ADA accommodation needs. Transportation and Accommodations Houston is served by two airports, George Bush Intercontinental (IAH) and William P. Hobby (HOU). Taxicabs are available at an estimated cost of $50-60 to or from each airport. SuperShuttle also operates a shuttle bus between each airport and area hotels. For more information, call 713-523-8888 or toll-free at 800-258-3826. Visit www.mdanderson.org/conferences for a list of area hotels. Conference Registration The University of Texas MD Anderson Cancer Center Comprehensive Surgical Approaches to the Skull Base (D120685) Sept. 26-30, 2018 THIS IS NOT A SELF-MAILER ADDRESS TO: CME/Conference Management Unit 1781 The University of Texas MD Anderson Cancer Center PO Box 301407, Houston, TX 77230-1407 Or fax to 713-794-1724. Make check or money order payable to: UT MD Anderson Cancer Center. Last Name First MI Highest degree Department (include unit) Institution Specialty Physician Street City State/Country/Zip or Mail code Email address Daytime phone Cell phone Fax Emergency contact Credit card holder name (first and last) Phone Yes No Authorized signature (required) Credit card number Expiration date CVV number (back of card) Credit card holder billing address & zip code MD Anderson Interdepartmental Transfer (IDT) No.: Business Unit Department Fund Group Fund Fund Type Authorized signature (required) IDT approver name (print first and last) MD Anderson employee ID No. (required) IDT approver email Registration Fees: Early registration postmarked by 8/1/18. Late registration postmarked after 8/1/18. Temporal Bone Module Early registration fee: $750.00 Late registration fee: $1,000.00 Anterior/Anterolateral Skull Base Module Early registration fee: $1,250.00 Late registration fee: $1,500.00

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