FY 2008 Appropriations for R&D and Public Health Programs (in millions)

FY 2008 Appropriations for R&D and Public Health Programs (in millions) AGENCY PROGRAM FY 2008 Appropriations Status: http://thomas.loc.gov/home/approp/app08.html FY 2008 : http://www.whitehouse.gov/omb/budget/fy2007/ Agency s: http://www.asm.org/policy/index.asp?bid=48354 10/26/07 PB % PB % PB National Institutes of Health* $28,899 $28,621-1.0% $29,650 2.6% ** 3.6% $29,900 3.5%** 4.5% NCI $4,798 $4,782-0.3% $4,870 1.5% 1.8% $4,910 2.3% 2.7% NHLBI $2,923 $2,925 0.1% $2,966 1.5% 1.4% $2,992 2.4% 2.3% NIDCR $390 $390 0.0% $396 1.5% 1.5% $399 2.3% 2.3% NIDDK $1,706 $1,708 0.1% $1,732 1.5% 1.4% $1,748 2.5% 2.3% NINDS $1,536 $1,537 0.1% $1,559 1.5% 1.4% $1,573 2.4% 2.3% NIAID ** $4,368 $4,592 5.1% $4,632 6.0% 0.9% $4,668 6.9% 1.7% NIGMS $1,936 $1,941 0.3% $1,966 1.5% 1.3% $1,979 2.2% 2.0% NICHD $1,255 $1,265 0.8% $1,274 1.5% 0.7% $1,282 2.2% 1.3% NEI $667 $668 0.1% $677 1.5% 1.3% $682 2.2% 2.1% NIEHS $642 $637-0.8% $652 1.6% 2.4% $656 2.2% 3.0% NIA $1,047 $1,047 0.0% $1,063 1.5% 1.5% $1,073 2.5% 2.5% NIAMS $508 $508 0.0% $516 1.6% 1.6% $520 2.4% 2.4% NIDCD $394 $394 0.0% $400 1.5% 1.5% $403 2.3% 2.3% NIMH $1,404 $1,405 0.1% $1,426 1.6% 1.5% $1,436 2.3% 2.2% NIDA $1,001 $1,000-0.1% $1,016 1.5% 1.6% $1,023 2.2% 2.3% NIAAA $436 $437 0.2% $443 1.6% 1.4% $446 2.3% 2.1% NINR $137 $138 0.7% $140 2.2% 1.4% $140 2.2% 1.4% NHGRI $486 $484-0.4% $494 1.6% 2.1% $497 2.3% 2.7% NIBIB $297 $300 1.0% $303 2.0% 1.0% $304 2.4% 1.3% NCRR $1,133 $1,112-1.9% $1,171 3.4% 5.3% $1,178 4.0% 5.9% NCCAM $122 $122 0.0% $123 0.8% 0.8% $124 1.6% 1.6% NCMHD $199 $194-2.5% $203 2.0% 4.6% $204 2.5% 5.2% FIC $66 $67 1.5% $68 3.0% 1.5% $68 3.0% 1.5% NLM $329 $321-2.4% $325-1.2% 1.2% $328-0.3% 2.2% OD *** $1,047 $517-50.6% $1,114 6.4% 115.5% $1,146 9.5% 121.7% B&F $81 $136 67.9% $121 49.4% -11.0% $121 49.4% -11.0% * The FY 2007 and FY 2008 levels are based on the FY 2008 Committee Report. ** The FY 2008 Request for NIAID, the FY 2008 and the FY 2008 Committee, include $300 million that would transfer to the Global Fund for HIV/AIDS, TB; the FY 2007 Joint Resolution includes approximately $99 million for the Global Fund. The recommendation for NIH for FY 2008 is 2.8% over FY 2007, when adjusted for the Global Fund transfer and the recommendation is a 1.9 percent increase when adjusted. *** The FY 2007 funding level directs $483 million to be used for the Common Fund and $69 million is for the National Children's Study; the FY 2008 directs $495 million to the Common Fund and $110.9 million to the National Children's Study; the FY 2008 Committee directs $531 million to the Common Fund and $110.9 million to the National Children's Study. The and specify the amount for the Common Fund, authorized int he 2006 NIH Reform Act, and do not transfer the 1.3 percent each IC for the Common fund that is in the budget request for FY 2008. American Society for Microbiology 1

AGENCY PROGRAM PB % PB % PB Centers for Disease Control & Prevention * $6,203 $5,983-3.5% $6,449 4.0% 7.8% $6,427 3.6% 7.4% Infectious Diseases $1,804 $1,794-0.6% $1,912 6.0% 6.6% $1,775-1.6% -1.1% Pandemic Influenza $70 $158 125.7% $158 125.7% 0.0% $158 125.7% 0.0% HIV/AIDS, Viral Hepatities, STDs, TB Prevention ** $1,010 $1,057 4.7% $1,041 3.1% -1.5% $1,020 1.0% -3.5% Zoonotic, Vector-Borne, and Enteric Diseases $70 $63-10.0% $70 0.0% 11.1% $70 0.0% 11.1% Hanta Virus/Special Pathogens $4 $4 0.0% Lyme Disease $5 $5 0.0% West Nile Virus $37 $20-45.9% $37 0.0% 85.0% Food Safety $29 $29 0.0% Chronic Fatigue Syndrome $5 $5 0.0% Preparedness, Detection, and Control of Infectious Diseases $156 $130-16.7% $164 5.1% 26.2% $157 0.6% 20.8% Antimicrobial Resistance $17 $17 0.0% $19 11.8% 11.8% Patient Safety $3 $3 0.0% All Other Emerging Infectious Diseases $104 $109 4.8% $137 31.7% 25.7% Global Health $334 $380 13.8% $381 14.1% 0.3% $334 0.0% -12.1% Environmental Health and Injury $288 $288 0.0% $305 5.9% 5.9% $296 2.8% 2.8% Buildings & Facilities $134 $20-85.1% $20-85.1% 0.0% $220 64.2% 1000.0% Terrorism Preparedness and Response (Bioterrorism) $1,541 $1,504-2.4% $1,589 3.1% 5.7% $1,632 5.9% 8.5% * The adopted an amendment sponsored by Senators Harkin (D-IA), Kennedy (D-MA), and Specter (R-PA), that states $5,000,000 shall be for activities to reduce infections methicillin-resistant staphylococcus aureus (MRSA) and related infections. The $5 million will be provided by the appropriated sums under the Agency for Healthcare Research and Quality to focus on identifying and containing. * The adopted an amendment sponsored by Senator Coburn (R-OK), that eliminates wasteful spending by the Centers for Disease Control and Prevention, specifying that none of the funds provided to the CDC shall be used for the Ombudsman Program or additional rotating paste lights, zero-gravity chairs, or dry-heat saunas for its fitness center. * The FY 2007 and FY 2008 levels are based on the FY 2008 Committee Report. ** The adopted an amendment, sponsored by Senator Enzi (R-WY), that would bar the use of funds in the bill to modify funding formulas for HIV/AIDS programs under Title XXVI of the Public Health Service Act, preventing a redistribution of HIV/AIDS funds included in the bill. American Society for Microbiology 2

AGENCY PROGRAM PB % HHS-Wide Pandemic Influenza */** $164 $1,192 626.8% $1,146 Activities Funded with No-Year Funding PB % PB HHS Office of the Secretary Public Health and Social Services $948 $948 0.0% $888-6.3% Emergency Fund ** Vaccines and Antivirals: Achieve Production Capacity and/or Buy Vaccine $543 $652 20.1% Purchase Antivirals $248 Advanced Deveopment of Antigen Sparing Techniques and Antiviral Drugs Enhance Strategic National Stockpile State and Local Preparedness Antiviral Subsidy to States Vaccine Registry Rapid Diagnostics (CDC) $79 HHS Office of the Secretary $79 $78-1.3% $78-1.3% 0.0% $78-1.3% 0.0% Activities Funded in the Agency s CDC $70 $158 $158 125.7% 0.0% $158 0.0% FDA $50 $51 2.0% NIH $35 $35 0.0% $35 0.0% 0.0% * The FY 2007 and FY 2008 levels are based on the FY 2008 Committee Report. **The FY 2008 Request for HHS-Wide Pandemic Influenza activites includes $870 million to fund the development of vaccines, antiviral drugs, and new tests to rapidly diagnose the disease, while $322 million would fund ongoing activities withing the CDC, FDA, NIH, and the Office of the Secretary. The FY 2008 Committee for HHS-Wide Pandemic Influenza activites includes $652 million to be available until expended fund the pre-pandemic vaccine for stockpiling,vaccine development, antiviral drugs, and research and development of diagnostic tests, while $78 million would fund ongoing activities within the the Office of the Secretary, and $158 million would be trasferred to the CDC to fund ongoing pandemic influenza activities. The FY 2008 for HHS-Wide Pandemic Influenza activities includes $870 million to fund the development of vaccines, antiviral drugs, and new tests to rapidly diagnose the disease, while $271 million would fund ongoing activities withing the CDC, NIH, and the Office of the Secretary. Since FY 2006, the Federal government has provided approximately $7 billion for pandemic influenza. FY 2007 Emergency Supplemental Pandemic Influenza HHS Office of the Secretary Public Health and Social Services Emergency Fund * $663 * These funds are intended for the purchase of antivirals, vaccine capacity building, retrofitting production facilities and accelerating the development of cell-based vaccines. Tuberculosis (TB) CDC $137 $137 0.0% $147 7.3% 7.3% NIH NIAID $129 Department of State * $50 * The adopted an amendment by Donald M. Payne, D-N.J., to shift $50 million in the bill to tuberculosis treatment, by taking $25 million within the child survival and health account and $25 million the economic support fund. According to preliminary reports, funding would go to Africa, to purchase drugs, train health care workers and build and equip and operate laboratories. American Society for Microbiology 3

AGENCY PROGRAM HHS-Wide Bioterrorism and Emergency Response Activities PB % PB % PB $4,148 $4,289 3.4% Centers for Disease Control and Prevention $1,541 $1,504-2.4% $1,589 3.1% 5.7% $1,632 5.9% 8.5% Biosurveillance Initiative $78 $88 12.8% $81 3.8% -8.0% $78 0.0% -11.4% CDC Capacity $137 $137 0.0% $137 0.0% 0.0% $137 0.0% 0.0% State and Local Capacity $824 $698-15.3% $790-4.1% 13.2% $760-7.8% 8.9% Strategic National Stockpile $491 $581 18.3% $581 18.3% 0.0% $581 18.3% 0.0% Anthrax Research Study $14 $0 $10-28.6% Quarantine Stations $11 National Institutes of Health $1,731 $1,723-0.5% Biodefense Research $1,610 $1,628 1.1% Radiological/Nuclear/Chemical Countermeasures Research $97 $96-1.0% $95-2.1% -1.0% $96-1.0% 0.0% Extramural Laboratory Construction $25 $0 Food and Drug Administration $217 $242 11.5% Food Defense $156 $178 14.1% Vaccines/Drugs/Diagnostics $55 $57 3.6% Physical Security $7 $7 0.0% $652 $781 19.8% Operations $9 $13 44.4% Preparedness and Emergency Operations $15 $48 220.0% National Disaster Medical System $47 $53 12.8% $53 12.8% 0.0% $53 12.8% 0.0% HHS Office of the Secretary Hospital Preparedness Grants ** $367 $414 12.8% $451 22.9% 8.9% $439 19.6% 6.0% Training and Curriculum Development ** $21 $0 International Early Warning Surveillance $9 $9 0.0% Media/Public Information Campaign $3 $2-33.3% Other 19 30 57.9% BARDA *** $211 $162-23.2% Advanced Research and Development **** $99 $189 90.9% $140 41.4% -25.9% $189 90.9% 0.0% BioShield Management $22 $22 0.0% $22 0.0% * The FY 2007 and FY 2008 levels are based on the FY 2008 Committee Report. ** Reflects comparable adjustments in FY 2006 and FY 2007 the Health Resources and Services Administration (HRSA) to the Office of the Secretary for preparedness and emergency response programs. *** Biomedical Advanced Research and Development Authority (BARDA), a newly created authority to coordinate research and produce vaccines an countermeasures against potential plagues and bioweapons. **** Reflects comparable adjustments in FY 2006 and FY 2007 of $50 million the NIAID to the Office of the Secretary for advanced development of biodefense countermeasures. **** The adopted and amendment, sponsored by Senator Burr (R-NC), that increases funding for the Public Health and Social Services Emergency Fund (PHSSEF) by $30 million to be used for the development of biodefense medical countermeasures by fully funding the Biomedical Advanced Research and Development Authority (BARDA). It specifically inserts the following under the PHSSEF section that $189,000,000 shall be used to support advanced research and development of medical countermeasures, consistent with section 319L of the Public Health Service Act. This $30 million increase is funded through a $30 million decrease in the Department of Education appropriation. American Society for Microbiology 4

AGENCY PROGRAM PB % PB % PB Food and Drug Administration (Includes drug, device, and animal drug user fees; and Buildings and $1,982 $2,042 3.0% $1,710-13.7% -16.3% $2,281 15.1% 11.7% Facilities) Foods $457 $467 2.2% $467 2.2% 0.0% $522 14.2% 11.8% Human Drugs $315 $324 2.9% $324 2.9% 0.0% $356 13.0% 9.9% Biologics $145 $155 6.9% $155 6.9% 0.0% $159 9.7% 2.6% Animal Drugs and Feeds $95 $95 0.0% $95 0.0% 0.0% $98 3.2% 3.2% Medical Devices $231 $240 3.9% $240 3.9% 0.0% $243 5.2% 1.3% * The levels are based on the Appropriations Committee recommended levels. * The FY 2007 and FY 2008 levels are based on the FY 2008 Committee Report. Department of Homeland Security Science and Technology Directorate (Research, Development, Acquisitions, and Operations) $749 $657-12.3% $646-13.8% -1.7% $697-6.9% 6.1% Chemical and Biological * $229 $229 0.0% $215-6.1% -6.1% $216-5.7% -5.7% Laboratory Facilities ** $106 $88-17.0% $89-16.0% 1.1% $104-1.9% 18.2% University Programs $49 $39-20.4% $49 0.0% 25.6% $39-20.4% 0.0% BioWatch $78 $79 1.3% $77-1.3% -2.5% $79 1.3% 0.0% National Biosureillance Integration System $8 $8 0.0% $8 0.0% 0.0% $8 0.0% 0.0% * The FY 2007 level and FY 2008 reflect transfers of $84 million out of the Science and Technology Directorate Chemical and Biological program to the Office of Health Affairs for biosurveillance, the BioWatch program, and chemical response activities, which took place on March 31, 2007. The has also provided $28,170,000 for the Department s Science and Technology Directorate to fully fund the ongoing BioWatch generation 3 research to begin validation and pilot testing of three different prototypes and complete signatures to identify pathogens of concern. ** The FY 2008 and provide $11,000,000 is for the National Bio and Agrodefense Facility to be used to continue environmental studies necessary to determine which site will be selected for this nextgeneration biological and agricultural defense facility with construction is anticipated to begin in 2010. National Science Foundation * $5,981 $6,429 7.5% $6,499 8.7% 1.1% $6,553 9.6% 1.9% Biological Sciences Directorate $608 $633 4.1% Research & Related Activities $4,666 $5,132 10.0% $5,140 10.2% 0.2% $5,156 10.5% 0.5% Major Research Equipment & Facilities Construction $234 $245 4.7% $245 4.7% 0.0% $245 4.7% 0.0% Education & Human Resources $700 $750 7.1% $823 17.6% 9.7% $851 21.6% 13.5% * The adopted an amendment by Shelley Moore Capito (R-WV), to shift $10 million the NSF to the Office on Violence Against Women. American Society for Microbiology 5

AGENCY PROGRAM Department of Energy (Office Science) PB % PB % PB $3,797 $4,398 15.8% $4,514 18.9% 2.6% $4,497 18.4% 2.3% Basic Energy Sciences $1,197 $1,498 25.1% $1,498 25.1% 0.0% $1,512 26.3% 0.9% Biological and Environmental Research * / ** $462 $532 15.2% $582 26.0% 9.4% $605 31.0% 13.7% Biological Research $424 Climate Research $158 * The levels are based on the Appropriations Committee recommended levels. * The FY 2007 Joint Funding Resolution strips earmarks the BER budget, providing funding for the base BER research programs, the FY 2008 does the same. ** The FY 2008 notes that BER encompasses tow distinct efforts, Biological Research and Climate Research, and provides funding in separate subaccounts, and urges this practice in future fiscal years. Environmental Protection Agency * $7,725 $7,199-6.8% $8,086 4.7% 12.3% $7,773 0.6% 8.0% Science & Technology (not including the Superfund Transfers) $733 $755 3.0% $788 7.5% 4.4% $773 5.5% 2.4% Office of Research and Development $555 $540-2.7% $570 2.7% 5.6% Extramural Research Grants $14 STAR Grants ** $62 $56-9.7% STAR Fellowships $9 $6-33.3% $11 22.2% 83.3% * The levels are based on the Appropriations Committee recommended levels. ** The FY 2008 does not provide a specific funding level for the STAR Grants, but states that the Committee continues to stress the importance of the STAR program and has attempted to target increases in areas that will both expand research and support STAR programs, and finds reductions to STAR funding not acceptable. Targeted increases include a $20 million increase over FY 2007 in S&T Clean Air research, and a $5 million increase in S&T Clean Water research. American Society for Microbiology 6

AGENCY PROGRAM PB % PB % PB U.S. Department of Agriculture * $17,812 $17,830 0.1% $18,817 5.6% 5.5% $18,709 5.0% 4.9% CSREES $1,177 $1,044-11.3% $1,145-2.7% 9.7% $1,172-0.4% 12.3% National Research Initiative * $190 $257 35.3% $190 0.0% -26.1% $244 28.4% -5.1% Agricultural Research Service (not including Buildings and Facilities) $1,129 $1,022-9.5% $1,076-4.7% 5.3% $1,154 2.2% 12.9% Food Safety and Inspection Service $892 $930 4.3% $930 4.3% 0.0% $931 4.4% 0.1% APHIS (not including Buildings and $846 $946 11.8% $875 3.4% -7.5% $912 7.8% -3.6% Facilities) * The levels are based on the Appropriations Committee recommended levels. * Water Quality and Food Safety Integrated Activities, totaling $42 million, are shifted to NRI in the FY 2008 request and the Committee. The Committee does not include the transfer of programs, but does direct the Secretary to provide the requested increase for bioenergy and bio-based fuels research within the funds provided. National Aeronautics and Space Administration National Oceanic and Atmospheric Administration $16,264 $17,309 6.4% $17,599 8.2% 1.7% $17,460 7.4% 0.9% Science $5,251 $5,516 5.0% $5,696 8.5% 3.3% $5,655 7.7% 2.5% * The adopted an amendment, sponsored by Senator Mikulski (D-MD), appropriating $10 million to a cross-agency effort to distribute, in equal increments, to each of NASA s 10 centers for the development of educational activities in science, technology, engineering, and mathematics related to the civilian space program of the United States Operations, Research, and Facilities $2,813 $2,855 1.5% $2,860 1.7% 0.2% $3,037 8.0% 6.4% U.S. Geologic Survey $983 $975-0.8% $1,033 5.1% 5.9% $1,010 2.7% 3.6% Biological Research Division $178 $181 1.7% $187 5.1% 3.3% $182 2.2% 0.6% Water Resource Division $215 $212-1.4% $223 3.7% 5.2% $224 4.2% 5.7% * The levels are based on the Appropriations Committee recommended levels. American Society for Microbiology 7