STTR TRANSFORMATIVE TEAM GRANTS APPLICATION

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2015 STTR TRANSFORMATIVE TEAM GRANTS APPLICATION Application Deadline: May 20, 2015 BLADDER BRAIN BREAST COLORECTAL HEAD & NECK LUNG OVARIAN PANCREAS PROSTATE

APPLICATION REQUIREMENTS Solid Tumor Translational Research (STTR) Transformative Team Grants Opportunity: Multiple $50,000 grants are available to STTR faculty. Requirements: Innovative and collaborative translational research proposals with clear hypothesis, aims and outcomes to propel the field. Favorable scoring will be given to projects that articulate a clear plan to move to a clinical trial within the next five (5) years. Suggested collaborations might include a computational biologist and a cancer biologist using existing data sets, a clinician and a researcher, a clinician and a pathologist, or a radiologist and a scientist using mouse models. STTR will release $50,000 direct cost awards, with no additional F&A (at UW/UWMedicine, it is up to you to consult the sign off process for awards received without F&A as per your departmental guidelines. At Fred Hutch, awardees are approved to use for direct cost, salary and fringe.). Staffing: Must include one STTR Fred Hutch employee (primary appointment is at Fred Hutch) and, at least, one other STTR faculty from a different discipline. APPLICATION SUBMISSION IMPORTANT DATES Letter of Intent Deadline February 20, 2015 LOI Decisions / Invitations for Full Proposals March 20, 2015 Application Deadline ** May 20, 2015 Applicant Notified of Award June 26, 2015 STTR Conference / Retreat presentation of results ** UW Investigators: Final applications must be submitted to OSP three full business days before the submission deadline, per UW policy (GIM 19) Completed applications must be submitted electronically in a single PDF document to Jalle Gebisa, Research Coordinator, STTR (STTRCancer@fredhutch.org). All deadlines are due by 11:59 pm PT. TBD 1

2015 STTR TRANSFORMATIVE TEAM GRANTS LETTER OF INTENT FORM STTR CANCER TYPE: Bladder Breast Head & Neck Ovary Prostate Brain Colorectal Lung Pancreas Sarcoma Project Title: Project Team Name Primary Appointment (Fred Hutch or UW/UWM) Department/ Division Title/Position (PI/Co-PI, Co-I) Email Letter of Intent (maximum one page): State your major aims and desired funding amount. Include one image or diagram to represent your proposal. Deadline: February 20, 2015 2

2015 STTR TRANSFORMATIVE TEAM GRANTS FUNDING APPLICATION FORM STTR CANCER TYPE: Bladder Breast Head & Neck Ovary Prostate Brain Colorectal Lung Pancreas Sarcoma Project Title: Project Team Name Primary Appointment (Fred Hutch or UW/UWM) Department / Division Title/Position (PI/Co-PI, Co-I) Email Funding duration is one year. Proposals for $50,000 grants must include two STTR faculty from two different disciplines (one STTR member must have a primary Fred Hutch appointment). Abstract (in 250 words or less): 3

2015 STTR TRANSFORMATIVE TEAM GRANTS BUDGET Name ROLE (PI/Co-PI/Key Personnel) Time & Effort (%) Direct Cost / Salary and Fringe Benefits SUPPLIES (specify and attach justification) SUBTOTAL: TRAVEL (specify and attach justification) PATIENT CARE COSTS (specify and attach justification) EQUIPMENT or MANUFACTURED PRODUCT (specify and attach justification) OTHER COSTS (specify and attach justification) TOTAL (DIRECT COSTS, should NOT exceed $50,000): Of the $50,000, TOTAL amount spent at Fred Hutchinson Cancer Research Center: 4

LAYMAN PROPOSAL: Use the format below. DO NOT exceed one (1-2) pages. 1. Layman Proposal: explains the significance of the research to the community, patient or disease. Language used must be at a high school reading level. This document will be used to distribute to potential donors via the FH Development and UWM Advancement Offices and, possibly, via the marketing departments at both institutions on the website to garner more exposure for your research. 2. Include one image or diagram to represent your proposal SCIENTIFIC PROPOSAL: Use the format below. DO NOT exceed five (5) pages for this section, including pictures, tables and figures. 1. Specific Aims 2. Background and Significance 3. Preliminary Data 4. Methods and Strategies. Attach in Additional Information below your approved or draft protocol, if available. 5. Timeline 6. Tables and Figures ADDITIONAL INFORMATION: 1. References 2. Biographical Sketch (NIH format: http://grants.nih.gov/grants/funding/phs398/biosketchsample.pdf) 3. IRB protocol, if applicable PRESENTATION: STTR Grant awardees will need to present at a future STTR retreat. Additional information will be presented to the awardees as the date approaches. 5