Material Safety Data Sheet NFPA HMIS Personal Protective Equipment 0 Health Hazard Fire Hazard 0 See Section 5. Section. Chemical Product and Company Identification Common Name/ Trade Name Manufacturer Neomycin sulfate SPECTRUM LABORATORY PRODUCTS INC. 4422 S. SAN PEDRO STREET GARDENA, CA 90248 Catalog Number(s). CAS# RTECS TSCA NE 405-0-3 QP4375000 Page Number: T SCA 8 (b ) i n ve n t o ry: Neomycin sulfate Commercial Name(s) Synonym Chemical Name Fradiomycin Sulfate; Bykomycin; Mycigient; Mycaifradin sulfate; Neofracin; Neomycine sulfate; Neomycin sulphate Neomycin, sulfate (salt) CI# IN CASE OF EMERGENCY CHEMTREC (24hr) 800-424-9300 Chemical Family Chemical Formula Supplier SPECTRUM LABORATORY PRODUCTS INC. 4422 S. SAN PEDRO STREET GARDENA, CA 90248 CALL (30) 56-8000 Section 2.Composition and Information on Ingredients Name CAS # Exposure Limits TWA (mg/m 3 ) STEL (mg/m 3 ) CEIL (mg/m 3 ) % by Weight ) Neomycin sulfate 405-0-3 00 Toxicological Data on Ingredients Section 3. Hazards Identification Potential Acute Health Effects Potential Chronic Health Effects Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. CARCINOGENIC EFFECTS: MUTAGENIC EFFECTS: TERATOGENIC EFFECTS: DEVELOPMENTAL TOXICITY: Repeated or prolonged exposure is not known to aggravate medical condition.
Neomycin sulfate Page Number: 2 Section 4. First Aid Measures Eye Contact Skin Contact Serious Skin Contact Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 5 minutes. Cold water may be used. Get medical attention if irritation occurs. Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold water may be used. Inhalation Serious Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Ingestion Serious Ingestion Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear. Section 5. Fire and Explosion Data Flammability of the Product Auto-Ignition Temperature Flash Points Flammable Limits Products of Combustion May be combustible at high temperature. Fire Hazards in Presence of Various Substances Explosion Hazards in Presence of Various Substances Fire Fighting Media and Instructions Fire Hazards Explosion Hazards Slightly flammable to flammable in presence of heat. Risks of explosion of the product in presence of mechanical impact: Risks of explosion of the product in presence of static discharge: SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet. Section 6. Accidental Release Measures Small Spill Large Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.
Neomycin sulfate Page Number: 3 Section 7. Handling and Storage Precautions Storage Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Do not breathe dust. If ingested, seek medical advice immediately and show the container or the label. Keep away from incompatibles such as acids. Keep container tightly closed. Keep container in a cool, well-ventilated area. Store at ambient (room) temperatures ranging from 5 to 30 degrees Celsius. Section 8. Exposure Controls/Personal Protection Engineering Controls Personal Protection Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of a Large Spill Exposure Limits Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Section 9. Physical and Chemical Properties Physical state and appearance Molecular Weight ph (% soln/water) Solid. 908.87 g/mole Odor Taste Color Boiling Point Melting Point Critical Temperature Specific Gravity Vapor Pressure Vapor Density Volatility Odor Threshold Water/Oil Dist. Coeff. Ionicity (in Water) Dispersion Properties See solubility in water. Solubility Partially soluble in cold water. Insoluble in diethyl ether, acetone. Solubility in Water: 6.3 mg/ml at 28 deg.c. Slightly soluble in alcohol. Practically insoluble in Chloroform.
Neomycin sulfate Page Number: 4 Section 0. Stability and Data Stability Instability Temperature Conditions of Instability Incompatibility with various substances Corrosivity The product is stable. Excess heat, incompatible materials Reactive with acids. Non-corrosive in presence of glass. Corrosivity Polymerization Will not occur. Section. Toxicological Information Routes of Entry Toxicity to Animals Chronic Effects on Humans Other Toxic Effects on Humans Toxicity to Animals Chronic Effects on Humans other Toxic Effects on Humans Inhalation. Ingestion. Acute oral toxicity (LD50): >8000 mg/kg [Mouse]. Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation. Acute Potential Health Effects: Skin: May cause mild skin irritation. Eyes: May cause eye irritation. Inhalation: May cause respiratory tract irritation. Ingestion: May cause anorexia, increased thirst, nausea, vomiting, diarrhea, skin rash. May affect behavior/central nervous system/nervous system (somnolence, dizziness, muscle twitching, clumsiness, hallucinations, convulsions/seizures, numbness, tingling). Chronic Potential Health Effects: Ingestion: Repeated or prolonged ingestion of large amounts may affect the urinary system (amount or frequency of urination, kidneys- interstitial nephritis, renal failure, tubular necrosis), blood (changes in serum composition), hearing (hearing loss, ringing or buzzing in the ears) and also cause symptoms similar to that of acute ingestion. Medical Conditions Aggravated by Exposure: Hypersensitivity to material; myasthenia gravis, Parsinson's disease; impaired kidney function; eighth-cranial nerve (hearing) impairment; ulcerative lesions of the bowl; intestinal obstruction; dehydration. Section 2. Ecological Information Ecotoxicity BOD5 and COD Products of Biodegradation Toxicity of the Products of Biodegradation the Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Neomycin sulfate Page Number: 5 Section 3. Disposal Considerations Waste Disposal Waste must be disposed of in accordance with federal, state and local environmental control regulations. Section 4. Transport Information DOT Classification Identification Not a DOT controlled material (United States). Special Provisions for Transport DOT Section 5. Other Regulatory Information and Pictograms Federal and State Regulations California Proposition 65 Warnings Other Regulations California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer, birth defects or other reproductive harm, which would require a warning under the statute: Neomycin sulfate California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: Neomycin sulfate TSCA 8(b) inventory: Neomycin sulfate California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: Neomycin sulfate EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS No. 25-773-). Canada: Listed on Canadian Domestic Substance List (DSL). China: Not lhisted on National Inventory. Japan: Not listed on National Inventory (ENCS). Korea: Listed on National Inventory (KECI). Philippines: Not listed on National Inventory (PICCS). Australia: Listed on AICS. Other Classifications WHMIS (Canada) Not controlled under WHMIS (Canada). DSCL (EEC) This product is not classified according to the EU regulations. HMIS (U.S.A.) Health Hazard Fire Hazard 0 National Fire Protection Association (U.S.A.) Health 0 Flammability Personal Protection E Specific hazard WHMIS (Canada)
Neomycin sulfate Page Number: 6 DSCL (Europe) TDG (Canada) ADR (Europe) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety glasses. Section 6. Other Information MSDS Code References Other Special Considerations N350 Validated by Sonia Owen on 2/6/2009. Verified by Sonia Owen. Printed 3/3/2009. CALL (30) 56-8000 Notice to Reader All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products, Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.