Biology 42A Human Physiology Gerstenzang 124 M, W, Th 8:00am- 8:50am Instructor Dr. Maria Miara, PhD mmiara@brandeis.edu Volen 208 (enter through 206) Office hours: Tuesdays 9:30-10:30, Fridays 10:00-11:00 Teaching Assistant Elena Insley einsley@brandeis.edu Course Description Physiology, according to American Physiological Society, is the study of life, and how genes, cells, tissues, and organisms function. Physiologists are occupied with research on key physiological concepts of body systems function. The investigation of living systems at many levels includes molecular processes, cell function, and behavior of isolated tissues, organ systems and the whole organism. The physiologists work is not limited to cell and tissue culture and animal experiments but includes research in human subjects. Physiological studies of normal function provide the basis to understanding abnormal function that occurs in pathological states. Physiologists are always trying to understand the functional body responses to a variety of internal and external environmental challenges. In this context the physiology course is designed to provide students with an understanding of the function and regulation of organ systems and integration of all systems in the human body. In addition, the importance of mechanisms of communication and control/ regulation to integrate all organ systems to maintain the homeostasis will be emphasized. Course content will include principles of homeostasis, neural & hormonal control mechanisms, sensory systems, muscle physiology, bone physiology, cardiovascular, respiratory, digestive and metabolism, renal, endocrine and reproductive systems. Prerequisites It will be assumed that students taking this class will have successfully completed courses in cell biology and genetics. At Brandeis this would include BIOL 14a or BIOL 22A and BIOL 15b or BIOL 22b. Students who feel they need a refresher on these topics should refer to Biology: How Life Works, James Morris et al. 2013 and/or read Chapters 2 through 5 in Vander s Human Physiology (see below).
Textbook Vander s Human Physiology, 13 th edition, Widmaier et al. 2013. McGraw Hill Publishers Copies of the book are available for purchase or rent through the Brandeis bookstore. Also, I have requested that multiple copies be placed on reserve at the library. Earlier editions of the text are available at more economical prices and you are free to use them if you wish. However, all references to the text (page numbers, figure numbers, etc) will be based on the 13 th edition. Academic Honesty You are expected to be familiar with and to follow the University s policies on academic integrity (see http://www.brandeis.edu/studentlife/sdc/ai ). Faculty may refer any suspected instances of alleged dishonesty to the Office of Student Development and Conduct. Instances of academic dishonesty may result in sanctions including but not limited to, failing grades being issued, educational programs, and other consequences. Disabilities If you are a student who needs academic accommodations because of a documented disability, please contact me and present your letter of accommodation as soon as possible. If you have questions about documenting a disability or requesting academic accommodations, you should contact Beth Rodgers- Kay in Academic Services (x6-3470 or brodgers@brandeis.edu.) Letters of accommodation should be presented at the start of the semester to ensure provision of accommodations. Accommodations cannot be granted retroactively. Student Responsibilities 1. Students are expected to be familiar with all information presented on this syllabus and to check the course Latte site regularly for changes 2. Students are expected to attend lectures and be knowledgeable of all material presented therein including all announcements 3. Students should contact the professor in a timely manner if there are any questions or concerns about their performance in the class. 4. Students should arrive on time and be prepared for all lectures 5. Students should read all e- mails sent by the professor or Teaching Assistants 6. Students should regularly check the LATTE course website for handouts, course information and any changes to the syllabus.
Evaluation This syllabus is subject to change. Please check back frequently for updates. 30 Points Class Participation 1 point per lecture 0.5 point for being physically present 0.5 point for being mentally present Cannot earn more than 30 points 20 Points - Weekly Responses Due at noon every Sunday Links to response forms are available on the course Latte site In order to access the form students must be logged in to their Brandeis account and logged out of any personal Google account. 2 points each, complete 10 out of 13 for full credit. 40 Points Group Presentation 18 minute presentation, 5 minutes of questions Describe the pathophysiology of a medical disease or disorder See handout for more details Students who have not signed up by January 21 using Latte form will be assigned a group 80 Points 2 best scores of: 40 Points - Test 1, Monday, February 23rd Relates to material covered during lectures 1-13 40 Points Test 2, Monday, March 30 Relates to material covered during lectures 14-27 40 Points Test 3, Taken with Final exam, tentatively scheduled for May 4, 1:30pm Relates to material covered during lectures 28-37 30 Points Cumulative Final Exam, Tentatively scheduled for May 4, 1:30pm 200 Points TOTAL ***THERE WILL BE NO OPPORTUNITIES FOR EXTRA CREDIT***
Lecture Date Day Topic Reading 1 01/12 M Introduction, Homeostasis and Feedback cycles Chapter 1 2 02/14 W Homeostatic Controls and Processes 3 01/15 Th Nervous System I Chapter 6 4 01/21 W Nervous System II 5 01/22 Th Sensory System I Chapter 7 6 01/26 M Sensory System II 7 01/28 W SNOW DAY 8 01/29 Th The Brain Chapter 8 9 02/02 M SNOW DAY 10 02/04 W Groups 1 and 2 Present 11 02/05 Th Muscle I Chapter 9 12 02/09 M Muscle II Chapter 10 13 02/11 W Bone : Growth and Maintenance Chapter 11.17-11.22 14 02/12 Th Endocrine I: Hormones Chapter 11.1-11.7 TEST 1 02/23 M Test 1 Covering Lectures 1-13 15 02/25 W Endocrine II:Hypothalamus, Pituitary and Thyroid Chapter 11.8-11.12 16 02/26 Th Endocrine III: Stress and Growth Chapter 11.13-11.16 17 03/02 M Groups 3 and 4 Present 18 03/04 W Cardiovascular I: Cardiac Cycle Chapter 12.1-12.7 19 03/05 Th Cardiovascular II: Vascular System Chapter 12.8-12.12 20 03/09 M Cardiovascular III: Control and Pathophysiology Chapter 12.13-12.25 21 03/11 W Respiratory I: Ventilation Chapter 13.1-13.2 22 03/12 Th Respiratory II: Gas exchange Chapter 13.3-13.6 23 03/16 M Respiratory III: Control and Pathophysiology Chapter 13.7-13.9 24 03/18 W Groups 5 and 6 Present 25 03/19 Th Renal I: Structure and Basic Function Chapter 14.1-14.5 26 03/23 M Renal II: Maintaining Water Balance Chapter 14.6-14.15 27 03/25 W Renal III: Maintaining Ion Balance, Pathophysiology Chapter 14.16-14.20 28 03/26 Th Digestion, Absorption and Digestive Regulation Chapter 15. 1-15.6
TEST 2 03/30 M Test Covering Lectures 14-27 29 04/01 W Groups 7 and 8 Present 30 04/02 Th Energy Balance Chapter 16 31 04/13 M Reproduction I: Introduction, Male Physiology Chapter 17.1-17.11 32 04/15 W Reproduction II: Female Physiology Chapter 17.12-17.18 33 04/16 Th Groups 9 and 10 Present Immune System I: 34 04/20 M Introduction, Innate Immune Chapter 18.1-18.2 Responses 35 04/22 W Immune System II: Adaptive Immune Responses Chapter 18.3-18.4 36 04/23 Th Immune System III: Immunoviruses, Harmful Immune Responses Chapter 18.6 37 04/27 M Groups 11 and 12 Present