ACG S IBD SCHOOL WESTERN REGIONAL COURSE

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2019 ACG'S IBD SCHOOL & WESTERN REGIONAL POSTGRADUATE COURSE JANUARY 18-20, 2019 THE COSMOPOLITAN, LAS VEGAS, NV ACG S IBD SCHOOL EARN UP TO CME EARN 8. 5 CREDITS UP TO 8. 5 MOC POINTS WESTERN REGIONAL COURSE EARN UP TO CME EARN 12. 5 CREDITS UP TO 12. 5 MOC POINTS REGISTER ONLINE: MEETINGS.GI.ORG

2019 ACG'S IBD SCHOOL & WESTERN REGIONAL POSTGRADUATE COURSE MARK YOUR CALENDAR FOR ACG S IBD SCHOOL AND WESTERN REGIONAL POSTGRADUATE COURSE, JANUARY 18-20, 2019, AT THE COSMOPOLITAN, LAS VEGAS, NEVADA. Learn and earn CME and MOC while you stay and play in Las Vegas! Maximize your time and learning when you attend ACG s IBD School and the 2019 ACG Western Regional Postgraduate Course on Friday-Sunday, January 18-20, at The Cosmopolitan in Las Vegas. On Friday, January 18, prior to the start of the weekend course, the College will offer its popular one-day program, ACG s IBD School. Spend the day immersed in learning the art and science of IBD diagnosis, treatment, and monitoring. The Western Regional Postgraduate Course on Saturday and Sunday features leading experts who will delve into the common and not-so-common GI and hepatology disorders. Attend and you ll leave Las Vegas with clinical pearls you can incorporate in your practice. 2 ACG MEMBERS PAY ONLY $99 $ FOR 1-DAY IBD SCHOOL! Both programs will take place at The Cosmopolitan of Las Vegas. Centrally located on the Las Vegas Strip next to the Bellagio and across from Paris, you can also enjoy world-class entertainment, dynamic nightlife, a gourmet s paradise, and some casino action while attending these programs.

January 18-20, 2019 THE COSMOPOLITAN LAS VEGAS, NEVADA PROGRAM DESCRIPTION ACG's IBD School IBD is an area of gastroenterology that continues to see rapid developments in diagnostic and medical therapeutic options. ACG s IBD School is a day-long educational program that combines an immersion in IBD management with a clinical update on new therapeutic and monitoring approaches. The goals of this course are to improve clinical judgment and to address the art and science of IBD management. The program will educate attendees in a practical manner regarding the natural history of disease, modifiable risk factors for adverse outcomes, diagnostic and prognostic testing, and rational decision making for medical treatment. The program will also address changes in epidemiologic trends, advances in laboratory, radiographic and endoscopic modalities that directly impact diagnosis and management of IBD, as well as developments in surveillance of dysplasia in ulcerative colitis and Crohn's colitis. Some of the most challenging clinical scenarios, such as the approach to primary medication failure or secondary loss of response, will be discussed in great detail. This program is designed for gastroenterologists, gastroenterology trainees, primary care physicians, nurses, physician assistants, and nurse practitioners interested in the latest information on IBD management. Western Regional Postgraduate Course The field of gastroenterology continues to experience introductions of new and novel diagnostic techniques and therapeutic options affecting numerous areas of gastrointestinal disease management and patient care. This program is designed to explore those areas and will address management updates in a variety of GI and hepatic areas. The program will explore common problems using case-based presentations on chronic vomiting, abdominal pain and bloating, hereditary colon cancer, Barrett s esophagus, refractory IBD, eosinophilic esophagitis, as well as state-of-the-art updates on ergonomics in endoscopy, improving quality in your practice, enteral feeding, recurrent obscure GI bleeding, HCC, NAFLD, hepatitis C treatment, EMR and large polyps, esophageal strictures, LAMS, acute upper GI bleeding, pancreatic cystic lesions, PSC and cholangiocarcinoma, and practice management. The structure of the program includes a mix of didactic presentations delivered by expert faculty, question and answer periods, video presentations, smaller afternoon general sessions, and non-cme hands-on workshop sessions. This program is designed for gastroenterologists, primary care physicians, nurses, physician assistants, and nurse practitioners interested in the latest information on diagnostic GI and liver diseases and state-of-the-art treatment of these illnesses. 3

ACG'S IBD SCHOOL AGENDA COURSE DIRECTORS: Sunanda V. Kane, MD, MSPH, FACG, and David T. Rubin, MD, FACG FRIDAY, JANUARY 18, 2019 7:00 am Registration and Continental Breakfast 8:00 am Welcome and Introductions David T. Rubin, MD, FACG 8:10 am Understanding the Epidemiology and Natural History of IBD for Clinicians Michael V. Chiorean, MD 4 Describe the epidemiology, natural history, and theories regarding the development of IBD, and differentiate IBD from its mimics. 8:30 am Goals of Caring for the IBD Patient David T. Rubin, MD, FACG Analyze the available data and positioning in IBD management of patient-centered goals and published algorithms of care. 8:55 am Thoughtful Application of Diagnostic Tools in IBD: When to Use What Christina Y. Ha, MD, FACG Discuss the appropriateness and timing of various diagnostic tools in IBD and review pearls for their proper use. 9:15 am How to Think About Immune Suppressive Agents in the Era of Biologics Jonathan A. Leighton, MD, FACG Explain the roles and positioning of immune suppressive agents including steroids, thiopurines, methotrexate, and tacrolimus. 9:35 am Biological Therapies in IBD: The Revolution in IBD Fernando S. Velayos, MD, MPH 10:15 am Q & A Recognize the role of biologics including appropriate candidates, the various mechanisms of action, and data to support each. 10:30 am Refreshment Break 10:50 am Getting Your Patient the Medication You Prescribed: Tips and Tricks Shivani Patel, PharmD, BCPS Adapt a methodical approach to obtaining pre-authorizations and appealing denials for medical therapies in IBD. 11:10 am Drug and Disease Monitoring Gauree G. Konijeti, MD Critically analyze the available data supporting therapeutic drug monitoring, recommendations for pre-therapy testing, and proactive management while receiving therapies. 11:35 am Timing of Surgery and Prevention of Postoperative Recurrence Nimisha K. Parekh, MD, FACG Outline the management of IBD patients who are surgical candidates, and describe the management of patients in the postoperative period.

2019 ACG'S IBD SCHOOL AND WESTERN REGIONAL POSTGRADUATE COURSE JANUARY 18 20, 2019 THE COSMOPOLITAN, LAS VEGAS, NV 11:55 am Lunch and Q & A With the Faculty All faculty 1:30 pm Cancer Prevention in IBD Fernando S. Velayos, MD, MPH Summarize primary and secondary cancer prevention in IBD patients including the use of chromoendoscopy. 1:50 pm Management of EIM: Disease-Related, Disease-Unrelated, and Therapy-Related Jonathan A. Leighton, MD, FACG Identify non-gastrointestinal conditions associated with IBD and their management. 2:20 pm Complementary and Alternative Medicine in IBD Michael V. Chiorean, MD Interpret the evidence base for popular alternative therapies including medical marijuana, herbal remedies, and probiotics. 2:45 pm Refreshment Break 3:00 pm Diet and Nutrition Gauree G. Konijeti, MD Outline the evidence for different diets in managing patients with IBD. 3:25 pm The Pregnant Patient With IBD Christina Y. Ha, MD, FACG Discuss IBD management strategies before and during pregnancy. 3:50 pm Microscopic Colitis Nimisha K. Parekh, MD, FACG Describe the epidemiology and management of microscopic colitis. 4:15 pm Q & A with the Faculty All faculty 5:15 pm Course Wrap-Up and Take-Away Points David T. Rubin, MD, FACG 5:30 pm Course Adjourns MOBILE APP INFORMATION Included with your registration is complimentary access to the course presentations via the ACG Mobile App. The app can be used to view faculty presentations on tablets, mobile devices, and laptops. Attendees will be able to take notes and highlight key points on the presentation slides at the event, and can continue reviewing them after the course. PDFs of the presentations can be downloaded directly from the app or can be printed from the website version of the app. Pre-registrants will receive access to the app prior to the course to view, download, or print the presentation slides. (NOTE: A printed syllabus will not be provided.) 5

WESTERN REGIONAL POSTGRADUATE COURSE AGENDA COURSE DIRECTORS: Walter J. Coyle, MD, FACG, and Raquel E. Davila, MD, FACG SATURDAY, JANUARY 19, 2019 6:30 am Registration and Continental Breakfast in the Exhibit Hall 7:30 am Welcome Remarks and Announcements Walter J. Coyle, MD, FACG, and Raquel E. Davila, MD, FACG SESSION 1: A Day in the Life of a Gastroenterologist: Morning Clinic Case-Based Presentations Moderator: Walter J. Coyle, MD, FACG 7:35 am Chronic Vomiting in the Young Adult Case of a 19-Year-Old Man With Refractory Vomiting Walter J. Coyle, MD, FACG Discuss the evaluation and management of the patient with chronic vomiting, and consider possible etiologies including cannabinoid hyperemesis syndrome. 7:55 am Management of Abdominal Pain and Bloating Case of a 42-Year-Old Woman With Intermittent Abdominal Pain and Postprandial Bloating Lawrence R. Schiller, MD, MACG Define the diagnostic and therapeutic approaches to the patient with abdominal pain and bloating including the role of diet and FODMAPs. 8:15 am Approach to the Patient With Hereditary Colon Cancer Case of a 34-Year-Old Man With a Family History of Colon Cancer Carol A. Burke, MD, FACG Recognize key issues in hereditary colon cancer including diagnostic criteria, screening and surveillance strategies, and surveillance for extracolonic malignancies. 6 8:35 am Panel Discussion / Q & A

2019 ACG'S IBD SCHOOL AND WESTERN REGIONAL POSTGRADUATE COURSE JANUARY 18 20, 2019 THE COSMOPOLITAN, LAS VEGAS, NV SESSION 2: A Day in the Life of a Gastroenterologist: Afternoon Clinic- Case-Based Presentations Moderator: Raquel E. Davila, MD, FACG 8:55 am Endoscopic Management of Barrett s Esophagus and Early Cancer Case of a 53-Year-Old Man With Barrett s and High-Grade Dysplasia Raquel E. Davila, MD, FACG Analyze the available endoscopic therapies for Barrett s esophagus and early esophageal cancer including EMR, RFA, and cryoablation. 9:15 am Approach to the Refractory IBD Patient Case of a 22-Year-Old Man With Refractory Crohn s Disease David T. Rubin, MD, FACG Propose treatment alternatives for the patient with refractory IBD and define when inpatient treatment is indicated. 9:35 am New Issues in the Diagnosis and Management of Eosinophilic Esophagitis Case of a 26-Year-Old Man With Dysphagia Fouad J. Moawad, MD, FACG Illustrate the newest guidelines for eosinophilic esophagitis including updated diagnosis and management recommendations. 9:55 am Fecal Microbiota Transplantation Case of a 57-Year-Old Woman With Metastatic Melanoma and Suspected Recurrent C. difficile Colitis Neil H. Stollman, MD, FACG Identify current uses and indications for FMT, including immune mediated colitis, C. difficile colitis, and IBD, and discuss patient selection, procedural logistics, and patient outcomes. 10:15 am Panel Discussion / Q & A 10:35 am Refreshment Break / Visit the Exhibit Hall SESSION 3: Video Presentations: A Day in Your Endoscopy Unit Moderator: Douglas G. Adler, MD, FACG 10:55 am How to Approach the Large Polyp on Colonoscopy John C. Fang, MD Evaluate proper assessment of large polyps, and discuss advanced EMR techniques to ensure complete resection and avoid complications. 11:10 am Endoscopic Management of Difficult Esophageal Strictures Fouad J. Moawad, MD, FACG Discuss the different types of esophageal strictures, and review technical aspects of stricture dilation while avoiding perforation. 11:25 am Current Uses of Lumen-Apposing Metal Stents Douglas G. Adler, MD, FACG Describe the latest indications for lumenapposing metal stents (LAMS), and their use as an alternative to surgery, as well as their technical success, and complications. 11:40 am Endoscopic Techniques in the Management of Acute Upper GI Bleeding Elizabeth Rajan, MD Demonstrate and compare the currently available techniques for achieving successful hemostasis in upper GI bleeding. 11:55 am Panel Discussion / Q & A 12:15 pm Break / Lunch Provided 12:40 pm Luncheon Presentation: Ergonomics in Endoscopy Patrick E. Young, MD, FACG Assess the repetitive use injuries commonly sustained by endoscopists, and explore techniques to avoid injury. 1:40 pm Break / Dessert in the Exhibit Hall 7

WESTERN REGIONAL POSTGRADUATE COURSE AGENDA SATURDAY AFTERNOON GENERAL SESSIONS / HANDS-ON WORKSHOP SESSIONS: *Hands-on workshops do not offer CME. 2:00 pm Improving Quality in Your Practice Irving M. Pike, MD, FACG Describe current methods of monitoring quality in your practice, and discuss how to implement measures to ensure quality. OR Hands-on Workshop Session* 2:50 pm Everything You Need to Know About PEGs, PEJs, and Enteral Feeding John C. Fang, MD Identify the indications for endoscopic placement of enteral feeding tubes, patient selection, contraindications, technical aspects, and management of complications. OR Hands-on Workshop Session* 3:40 pm Year in Review: Best of The American Journal of Gastroenterology in 2018 Brennan M. Spiegel, MD, MSHS, FACG Outline the best AJG articles and guidelines with the highest impact on clinical practice. OR Hands-on Workshop Session* 4:30 pm Approach to the Patient With Recurrent Obscure GI Bleeding Carol E. Semrad, MD, FACG Choose an organized strategy for the diagnosis and management of obscure GI bleeding, and discuss the challenges of managing the patient with left ventricular assist devices and anticoagulation issues. OR Hands-on Workshop Session* 5:15 pm Adjourn for the Day 8 HANDS-ON WORKSHOPS Attendees have the opportunity to participate in the hands-on workshops at no additional charge. These sessions focus on specific endoscopic procedures, and offer participants a chance to gain tactile experience using a variety of tools and techniques. Faculty will demonstrate a device and/or technique, and attendees will be able to practice. While the handson workshop sessions do not offer CME, they are a valuable learning experience, and provide an opportunity for attendees to interact with the experts. Hands-on workshops will be concurrent with the general sessions Saturday afternoon. There are limited spaces available. Registrants are able to select their top two stations when they register for the course. The College will assign stations based on availability. HANDS-ON WORKSHOP SESSIONS 8 hands-on stations will be offered. The stations are: EMR Foreign Body Removal ESD Mucosal Ablation: RFA ERCP Mucosal Ablation: Cryotherapy Hemostasis Hemorrhoid Banding

2019 ACG'S IBD SCHOOL AND WESTERN REGIONAL POSTGRADUATE COURSE JANUARY 18 20, 2019 THE COSMOPOLITAN, LAS VEGAS, NV SUNDAY, JANUARY 20, 2019 7:00 am Registration and Continental Breakfast in the Exhibit Hall 7:55 am Welcome and Announcements Walter J. Coyle, MD, FACG, and Raquel E. Davila, MD, FACG SESSION 4: Current Issues in Liver Disease Moderator: Catherine T. Frenette, MD 8:00 am Diagnosis and Management of HCC Catherine T. Frenette, MD Discuss screening strategies for tumor detection, and specify current management options for hepatocellular carcinoma (HCC). 8:20 am What s New in NAFLD Stephen A. Harrison, MD Describe risk factors, diagnosis, disease progression, and current treatment options for nonalcoholic fatty liver disease (NAFLD). 8:40 am Challenges in Hepatitis C Treatment Norah A. Terrault, MD, FACG Summarize the advances in hepatitis C therapy, and discuss the approach to patients who may be challenging to treat. 9:00 am Panel Discussion / Q & A 9:20 am Refreshment Break / Visit the Exhibit Hall SESSION 5: Clinical Challenges in Your GI Practice Moderator: Carol E. Semrad, MD, FACG 9:40 am Diet, Probiotics, and Other Options in IBS Linda Anh B. Nguyen, MD Evaluate the myriad of complementary treatments for IBS including diet, probiotics, supplements, and alternative therapies. 10:00 am Global Management of the IBD Patient Nimisha K. Parekh, MD, FACG Discuss the global care of the IBD patient including vaccinations, bone health, diet, alternative therapies, pain management, cannabis use, and reduction of narcotic use. 10:20 am Challenging Issues in the Management of Gluten Sensitivity and Celiac Disease Carol E. Semrad, MD, FACG Explain current challenges in the care of patients with gluten sensitivity and celiac disease, and outline treatment strategies. 10:40 am Panel Discussion / Q & A SESSION 6: Update on Pancreatic and Biliary Diseases Moderator: Uzma D. Siddiqui, MD 11:00 am Evaluation and Management of Pancreatic Cystic Lesions Walter J. Coyle, MD, FACG Identify the types of pancreatic cysts, discuss diagnostic evaluation, and examine the varied guidelines for cyst management. 11:20 am Endoscopic Management of PSC and Cholangiocarcinoma Uzma D. Siddiqui, MD Outline the approach to managing primary sclerosing cholangitis (PSC) strictures, and discuss the role of ERCP and EUS in the early detection, diagnosis, staging, and management of cholangiocarcinoma. 11:40 am Panel Discussion / Q & A 12:00 pm Course Wrap-Up and Take-Away Points Walter J. Coyle, MD, FACG, and Raquel E. Davila, MD, FACG 12:15 pm Course Adjourns REGISTER BY DECEMBER 21 AND SAVE: MEETINGS.GI.ORG 9

PROGRAM DESCRIPTION / REGISTRATION INFORMATION REGISTRATION INFORMATION There are separate registration fees for ACG s IBD School and the Western Regional Postgraduate Course. The registration fee for each course includes admission to all sessions, continental breakfasts, lunch on Friday for ACG s IBD School attendees, lunch on Saturday for Western Regional Postgraduate Course attendees, and refreshment breaks. All registrants must pay the full registration fee; partial registration is not available. Full refund of registration fees will be given, less a $25 administrative fee, if written notice of cancellation is received by ACG by December 21, 2018. No refunds will be given after this date. ACG'S IBD SCHOOL REGISTRATION WESTERN REGIONAL COURSE REGISTRATION ACG MEMBER TYPE EARLY BIRD (by 12/21) FEE (After 12/21) ACG MEMBER TYPE EARLY BIRD (by 12/21) FEE (After 12/21) Physician $99 $200 Physician $449 $499 Resident / Trainee / Candidate $99 $200 Associate / Advanced Practice Provider $99 $200 NON-MEMBER TYPE Physician / PharmD / PhD / Guest $149 $250 Resident / Trainee $149 $250 NP / PA / Allied Health (RN, LPN) $149 $250 Resident / Trainee / Candidate $179 $254 Associate / Advanced Practice Provider $289 $364 NON-MEMBER TYPE Physician / PharmD / PhD / Guest $549 $599 Resident / Trainee $229 $304 ACG's IBD School is only $99 for ACG Members! NP / PA / Allied Health (RN, LPN) $289 $424 10

2019 ACG'S IBD SCHOOL AND WESTERN REGIONAL POSTGRADUATE COURSE JANUARY 18 20, 2019 THE COSMOPOLITAN, LAS VEGAS, NV ACCREDITATION / CME / MOC The American College of Gastroenterology is accredited by the American Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. ACG s IBD School The American College of Gastroenterology designates this live activity for a maximum of 8.5 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 8.5 MOC points in the American Board of Internal Medicine s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Western Regional Postgraduate Course The American College of Gastroenterology designates this live activity for a maximum of 12.5 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 12.5 MOC points in the American Board of Internal Medicine s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. ACCOMMODATIONS Both programs will be held at The Cosmopolitan of Las Vegas, centrally located on the Las Vegas Strip. Enjoy the Vegas nightlife and entertainment when you attend the course. To make reservations, please call The Cosmopolitan at 855-435- 0005 or 702-698-7575, or make your reservation online at https://book.passkey. com/go/samgi9. Special meeting rates per night are $239 single/double plus $25 discounted resort fee and 13.38% tax. The hotel accepts all major credit cards. Hotel reservations must be made by December 21, 2018 in order to receive the special meeting rate. Only a certain number of rooms are available at these rates and are available on a first-come, first-served basis. Once ACG s room block is sold out, the hotel may charge a higher rate for any additional rooms made available. Requests for reservations received after this date will be on a space-available basis only. Cancellations made within 72 hours of arrival will be charged one night s room and tax. Check-in is at 3:00 p.m. Check-out is at 11:00 a.m. The Cosmopolitan is located at 3708 Las Vegas Boulevard South, Las Vegas, Nevada. MORE INFORMATION For more information about these programs, contact ACG at education@gi.org. Americans with Disabilities Act (ADA): Attendees of these programs who need additional reasonable accommodations or who have special needs (including dietary needs) should contact the ACG office by email at registration@gi.org no later than December 21, 2018. 11

AMERICAN COLLEGE OF GASTROENTEROLOGY 6400 Goldsboro Road, Suite 200 Bethesda, MD 20817 2019 ACG'S IBD SCHOOL & WESTERN REGIONAL POSTGRADUATE COURSE JANUARY 18-20, 2019 THE COSMOPOLITAN, LAS VEGAS, NV REGISTER BY DECEMBER 21 AND SAVE! meetings.gi.org