One Lung Ventilation in Obese patients

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One Lung Ventilation in Obese patients YUSNI PUSPITA DEPARTEMEN ANESTESIOLOGI DAN TERAPI INTENSIF FAKULTAS KEDOKTERAN UNIVERSITAS SRIWIJAYA/RSMH PALEMBANG

One Lung Ventilation Lung isolation techniques are used in thoracic, esophageal, vascular, and nonthoracic surgical setting in the perioperative period. Method current use to achieve lung isolation : (1) Double lumen tube (DLT) technology (left and right double lumen endotracheal tubes (2) Bronchial blocking technology

OLV Perioperative hypoxemia during OLV is not uncommon caused by intrapulmonary shunt (this is related to collapse of the non-dependent lung and increased atelectatic areas in the dependent lung). Therefore the primary aim during OLV to provide adequate oxygenation and CO2 elimination, while the potential harmful effects of ventilatory strategy were initially disregarded. The use of high VT and high airway pressures during OLV increased risk of post pneumonectomy ARDS The use of low VT better outcome after thoracic surgery and less lung water content 4-6 ml/kgpbw

Summary of Lung Isolation Devices and Recommendations for Placement

Conversion Measurements of Tracheal Widths Based on Chest Radiograph and Bronchial Diameter Measurements Based on Computed Tomography Scan of the Chest and the Predicted Left-sided Double-lumen Endotracheal Tube Size

(A) Univent bronchial blocker; the optimal position of the Univent in the left mainstem bronchus. (B) Wire-guided endobronchial blocker (WEB); the optimal position of the WEB blocker in the left mainstem bronchus.

Techniques of OLV There are 3 techniques in OLV : Double-Lumen Endotracheal Tube (DLT) Single-Lumen Endotracheal Tube (SLT) Bronchial Blockers (BB) Usually used in practice DLT Usually used in obese patients BB

Bronchial blockers

EZ-Blockers

EZ Blocker is only BB that can be placed blindly without bronchoscopy Used in very small ETT (no pediatric FOB available) During emergencies ( blind without FOB) When airway cannot be visualized ie hemorrhage Miller CA, Sabhlok S, Brodsky JB. "Blind" placement of a bronchial blocker in a patient with a difficult airway. J Cardiothorac Vasc Anesth. 2013 Oct;27(5):e61 2.

Example of DLT positioning (LEFT) (A) View of the tracheal carina, towards the left side the endobronchial lumen is visible, the left main bronchus with the outer surface of the endobronchial balloon is seen below tracheal carina. (B) View of the 3 orifices of the right upper lobe bronchus (apical, anterior, and posterior segments). (C) Clear view of the left upper and left lower bronchus.

The DLT vs BB Controversy

The DLT vs BB Controversy Campos et al found both technique (DLT or BB) produce similar results in term the incidens of : Failed first attempts Malposition after achieving lateral decubitus position Time to lung deflation or surgical exposure

Favors DLT Displacement less frequent CPAP easily applied Allows suctioning before re inflation of operative lung during surgery Used for operations on contra lateral lung if main bronchus is obstructed faster and easier to place blind placement possible more rapid lung deflation sequential surgery split lung ventilation in ICU Favors BB Placed through ETT or LMA Difficult airway or when DLT impossible to use Can be used in situ ETT (no need to change to DL) Better when tube exchange dangerous, especially if postoperative ventilation needed multiport adaptor allows ventilation during placement less potential for serious airway trauma allows selective lobar isolation smallr airways and pediatrics

For most patients either a DLT or BB can be safely used the choice is one of personal preference No significant differences in the quality of lung isolation Both have advantages in specific clinical situations Anesthesiologists should be skilled in both techniques Clayton Smith A, et al. A comparison of the efficacy and adverse effects of double lumen endobronchial tubes and bronchial blockers in thoracic surgery: A systemic review and meta analysis of randomized controlled trials. J Cardiothor Vasc Anesth (2015) 29: 955 966

OLV in obese patient Literatur mengenai OLV pada pasien obese masih langka Seiring meningkatnya angka obesitas, perlu di pahami mengenai OLV pada pasien obesitas

Why does it matter? Because: The prevalence of Obesity is increasing worldwide

Why does it matter? Because: Difficult air way access short and redundant neck, limited extension, and Abundant fatty tissue on the neck, thoracic wall and abdomen

Why does it matter? Because: There are physiological changes

OLV in Obese Patient Essensial principles of ventilator management in obese pasient seems not to be different from the choices used in non-obese patient Past : Vt of 10 12 ml/kgpbw during OLV was recommended to maintain gas exchange and normalize arterial oxygen and carbon dioxide values (study by Katz) Fact : perioperative hypoxemia during OLV is not common, which results from an intrapulmonary shunt related to collapse of the nondependent lung and increased atelectatic areas in the dependen lung

OLV in Obese Patient Obese patient tend to suffer from collapse due to their decreased chest wall compliance The setting of optimal PEEP level to keep lung open may be crucial; inadequate PEEP level cannot prevent alveolar re-collapse after an alveolar recruitment maneuver Attention while performing recruitment maneuver : Temporary desaturation Decreased preload Hypotension Arrhytmias barotrauma

OLV in Obese Patient PEEP is crucial to treat and prevent atelectasis and hypoxemia Best level of PEEP during OLV remains unclear Ferrando et al. : individualized PEEP in a PEEP Decremental Trial resulted in better oxygenation and lung mechanics after an alveolar recruitment maneuver than administering a standardized 5 cmh2o of PEEP

OLV in Obese patient Alveolar recruitment strategies during OLV better oxygenation and decrease dead-space variables Excessive airway pressure increase pulmonary vascular resistance and shift blood flow to the non-dependent lung Michele et al. found that : 5-10 cmh2o PEEP improved oxygenation and ccontinuous lung volume recruitment 15 cmh2o PEEP overdistention and increased shunt Although PEEP is crucial to treat and prevent atelectasis HAVE TO BE CAREFUL when used

Watanabe et al: Sequential changes of arterial oxygen tension in the supine position during one lung ventilation. Anesth Analg. 2000; 90:28-34 Position and PaO 2 During OLV Left lateral decubitus Left semilateral Supine

Volume Control Volume Controlled One-Lung Ventilation (Controversy 2006) Protective Low Volume Ventilation Slinger P. Pro: Low tidal volume is indicated during one-lung ventilation. Anesth Analg. 2006;103: 268-70 Conventional High Volume Ventilation Gal TJ. Con: Low tidal volumes are indicated during one-lung ventilation. Anesth Analg. 2006;103: 271-3

Protective OLV minimizes VALI Volume controlled OLV Low tidal volume (4 6 ml/kg/ibw) Dependent lung PEEP Lowest FiO 2 (to maintain SpO 2 ) Recruitment maneuvers dependent lung Low ventilatory pressure Della Rocca G, et al. Acute lung injury in thoracic surgery. Curr Opin Anaesthesiol. 2013; 26: 40 6

Conventional OLV (VT 10 ml/kg, FiO2 1.0 + 0 PEEP) vs Protective OLV (VT 6 ml/kg, FiO2 0.5. + 5 cmh20 PEEP) PaO2 and PaO2/FiO2 higher in conventional group Interleukin 6 and malondialdehyde increased in both groups/no differences between groups No differences in post operative abnormalities orcxr NO ADVANTAGE TO PROTECTIVE OLV Ahn HJ, et al. Comparison between conventional and protective one lung ventilation for ventilator assisted thoracic surgery. Anaesth Intensive Care 2012; 40: 780 8

Summary OLV is a separation lung technique usually used in thoracic surgery Obese patients (moreover in morbidly obese patients) have higher risk in airway management including OLV because there are physiological changes. There are 3 techniques in OLV, but the most commonly used in obese patient is BB or SLT with BB. During OLV in obese patients, anaesthesiologists have to pay attention to VT, pressure, and PEEP Other considerations are: fluid, positions and volume control