Methylation SNPs. Sample Personalized Report. = Optional Foundational Support. Yellow / Red = Highly Recommended Nutritional Support

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Sample Personalized Report Green = Optional Foundational Support Yellow / Red = Highly Recommended Nutritional Support Grey = No genotype exists for this SNP Methylation SNPs Gene SNP What this SNP means Diet & Lifestyle CBS C699T This SNP may affect homocysteine levels. COMT V158M You may have difficulty metabolizing estrogens and certain neurotransmitters. FUT2 G772A This SNP may reduce risk of B12 deficiency, but it may also reduce the numbers of friendly bacteria in your digestive tract. You may need a vitamin B12 supplement. Your health care provider will determine the dose that is right for B12 5000 liquid 30 ml,puregenomics MTHFR A1298C ability to utilize folic acid. Eat plenty of green, leafy vegetables, which provide folate in a form the body can use. Discuss supplement options with your health care provider. Folate 1000,PureGenomics MTHFR C677T ability to utilize folic acid. Eat plenty of green, leafy vegetables, which provide folate in a form the body can use. Discuss supplement options with your health care provider. Folate 1000,PureGenomics

MTR A2756G This SNP may increase vitamin B12 requirements. MTRR A66G This SNP may increase vitamin B12 requirements. You may need a vitamin B12 supplement. Your health care provider will determine which product and what dose is right for PureGenomics TCN2 C766G This SNP may increase vitamin B12 requirements.

Vitamin SNPs Gene SNP What this SNP means Diet & Lifestyle ability to make vitamin A from BCMO1 A379V dietary beta carotene. Vitamin A is essential for immune defenses, healthy skin night vision, and macular health. BCMO1 R267S ability to make vitamin A from dietary beta carotene. Vitamin A is essential for immune defenses, healthy skin night vision, and macular health. Ensure adequate intake of vitamin A. If you do not eat foods like organ meats, eggs, cod liver oil and dairy products, your health care provider may recommend a supplement. Vitamin A + Carotenoids 90's GC Studies have linked this SNP with lower vitamin D levels, even with adequate dietary intake and/or sunlight exposure. You may need extra vitamin D. Your health care provider may recommend a supplement. Detoxification and Antioxidant Defenses Gene SNP What this SNP means Diet & Lifestyle GPx1P1 Pro198Leu Individuals with this SNP may benefit from extra selenium and higher intake of certain antioxidants. You may need extra vitamin D. Your health care provider may recommend a supplement. DIM Detox,Nrf2 Detox GSTP1 I105V This SNP may reduce the body s ability to eliminate certain toxins. No recommendations are available for this SNP.

SOD2 VAL16ALA Individuals with this SNP may have increased antioxidant requirements.

Metabolism & Weight Management SNPs Gene What this SNP means Diet & Lifestyle ADIPOQ No recommendations No recommendations No recommendations are available for this SNP. APOA2 No recommendations No recommendations No recommendations are available for this SNP. Reduced ability to FADS1 convert omega-3 fatty acid precursors (linolenic acid from flaxseed oil and other plant sources) to active omega-3 fatty acids (EPA and DHA). Ensure adequate intake of omega-3 fatty acids from cold-water fish or fish oil. Plant sources of omega-3 precursors, such as nuts, seeds and seed oils, may not provide optimal support. not to address this SNP for Genetic predisposition FTO to a higher body weight and body fat percentage. This is due, in part, to increased appetite and diminished satiety after meals. Carriers may be more likely to lose weight through diet and lifestyle modifications than non-carriers. Increase protein intake Consume a whole food based diet with an emphasis on colorful fruits and vegetables. The Mediterranean diet may reduce the impact of the FTO SNP on metabolic health. Get adequate sleep, which helps to reduce cravings Exercise regularly PureLean Protein Blend Chocolate Flavor

Methylation Pathway Vitamin D Vitamin A

Detoxification and Antioxidant Defenses Weight Management and Metabolic Health Essential Fatty Acids