Outbreak investigation

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Outbreak investigation Dr. Marius Masiulis FAO international consultant, State Food and Veterinary Service of Lithuania Regional Workshop on FMD and other TADs Yur'evets, Vladimir, Russian Federation 29/11/2017-30/11/2017 Outbreak investigation and traceability Does the practical & feasible measures to improve traceability systems for live animals, food products, feed, focusing on the challenges, that Veterinary Services face when investigating the origin and possible spread of disease, exist?... 2 1

Phases du plan THE 3 MAIN PHASES Watching over Suspicion Confirmation Setting up and updating of Contingency plans (CP) Identification of animals and updating of data basis; Training of the actors; Raising awareness; On duty 24h organization; Maintenance of alert network (vets, lab); Checking (transport, markets, slaughterhouses ) CP actors mobilization Sequestration of concerned & linked holdings Samplings for analysis Epidemiologic survey Notification (24 hours) (ADNS, WAHIS); Animal, products, people control; Protection and surveillance zones; Crises center set up; Experts groups mobilization; Culling + carcasses destruction; Decontamination. 3 Outbreak Who introduced? Who did spread? When introduced? When spread? How introduced? How spread? Where from introduced? Where to spread? How to prevent further spread? 4 2

Outbreak preparedness and investigation Outbreak preparedness Surveillance Planning Outbreak investigation Confirmation and assessment; Case definition; Case finding; Outbreak description; Hypothesis generation from the existing outbreak data; Analytic epidemiology; Conclusions. 5 Outbreak 6 3

LEGISLATION!!! Epidemiological inquiry... shall ensure that the epidemiological inquiry in relation to suspected cases or outbreaks of animal contagious diseases (FMD, CSF, ASF, AI and etc.) is carried out by specifically trained veterinarians on the basis of questionnaires, prepared within the framework of the contingency plans, to ensure standardised, speedy and targeted inquiries 7 Targeted inquiries the length of time during which the animal contagious disease may have been present on a holding before being suspected or notified; the possible origin of the animal contagious disease virus on a holding and the identification of other holdings where there are animals suspected of being infected or animals suspected of being contaminated from the same source; 4

Targeted inquiries the possible extent to which animals of susceptible species may have been infected or contaminated; the movement of animals, persons, vehicles and the substances (stocks of milk, milk products, meat, meat products, carcasses, hides and skins, wool, semen, embryos, ova, slurry, manure as well as animal feed and litter on the holding) likely to have carried the animal contagious disease virus / phatogen to or from the holdings in question. Outbreak investigation forms o Standard format to collect a standard set of data; o Should be space for non-standard information o Easy to complete; o Detailed information in combination with short and useful data; o Information for questionnaire is only the key for outbreak investigation really more on your eyes that on piece of paper 10 5

Tracing Direct interviewing on spot and thorough inspection of the farm and surrounding; Usage of all available data (validation, cross check, ID&R database, movement data and etc ) Usage of different sources of information on the same subject and logical checks and prove of theories; Data waste should be avoided 11 Other sources of information for veterinary service? Family, employees; Private veterinarians; Animal dealers; Slaughterhouses; Rendering plants; Feed suppliers; Neighbours. 12 6

Priorities for Tracing The number of contacts to be traced can become very large; Resources for investigations are not unlimited; Time can be critical Need to prioritise highest risk contacts! 13 KEY COMPONENTS TO AN OUTBREAK INVESTIGATION 1. Establish trust; 2. Be patient; 3. Keep an open mind; 4. Listen to what the farmer and his staff says; 5. Explain yourself and answer any questions they have; 6. Remember farmers talk to each other. 14 7

Traceability because identification alone does not ensure OIE (Code): ability to follow an animal or group of animals during all stages of its life; ISO (8402): ability to trace the history, application or location of an entity by means of recorded identifications. 15 Tracing Movements of animals, carcasses, semen, ova, meat or any material which could have carried virus or phatogen; Persons; Vehicles, equipment; Feed; Water, products, by-products; Other live vectors or wild animals; others (unknown?) 16 8

Tracing Collaboration with other authorities (municipalities, agricultural / rural organisations, associations, breeding services ); Continuous summarizing of knowledge and transmission of the information to decision makers (if any exist ); Use of external support (e.g. epidemiological services, task forces, etc.) difficult, but reasonable Continuous generation of hypothesis 17 Animal movement - Tracing Animal Identification and Registration Database; National Animal Disease reporting system; National / International documents leading animal during transportation or movement / animal health certificate; TRACES. 18 9

Steps towards animal traceability Holding registration; Animal identification; Movement records on farm; Central movement recording (group); Central movement recording (individual). 19 Outbreak commercial farm 20 10

Outbreak backyard farm 21 An example of one country Outbreak of ASF in commercial farm - pigs died with lesions resembling poisoning; -location of seropositive pigs. 22 11

Tracing the movement of pigs 23 Protection and surveillance zones The geographical delimitation of those two zones must take into account the administrative borders and natural barriers, where will be taken the surveillance and control measures that can stop animal disease virus spreading. Protection zone will have a radius of a minimum 3 kilometres, having the centre into outbreak, and the surveillance zone will have a radius of a minimum 10 kilometres, having the same centre. These two zones will be at least of 3 and 10 kilometres, but they might be enlarged, not necessary as a circle, but as any other geometrical form, varying with natural barriers and the administrative borders. 12

Measures in contact holdings Official supervision; Temporal restrictions: no meat, pig products, semen, ova or embryos of pigs, animal feed, utensils, materials or waste likely to transmit ASF may leave the holding without an authorization; no animal carcases may leave the holding without an authorisation No pigs may enter or leave the holding; Clinical examination, thermometry and observations; Sampling and testing in order to rule out the disease. 25 Measures in slaughterhouses Meat of animals slaughtered during the period between the probable introduction of the disease into the holding and the taking of official measures is wherever possible to be traced and processed under official supervision 26 13

What can be done additionally? Veterinary certification rules could be drawn up and implemented: before the movement of sustebtible animals from their keeping place clinical examination should be carried out and veterinary certificate should be issued 24 hours prior their movement Regular update of the Animal Identification and Registration Database; Additional training for animal keepers, private veterinarians and hunters on biosecurity requirements, clinical signs and diagnosis of animal contagious diseases, animal registration and identification, pig keeping welfare requirements 27 PREVENTION IS BETTER THAN CURE ON-FARM BIO-SECURITY MEASURES ARE CHEAPER THAN OUTBREAK ERADICATION 28 14

Any questions?! 29 Thank you for your attention 29-30 November 2017 Regional Workshop on FMD and other TADs 30 15