MEMBERSHIP OF PROFESSIONAL BODIES:

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1 PERSONAL DETAILS: Name: Address: Mr Nicos Kessaris BSc, MBBS, MSc, FRCS(Eng) Department of Nephrology and Transplantation 6th Floor, Borough Wing Guy's Hospital Great Maze Pond London SE1 9RT Telephone Numbers: +44 (0) (personal) Date of Birth: 8th October 1969 Present Appointment: -Consultant Transplant and General Surgeon, Guy s and St Thomas Hospital, London -Honorary Consultant Great Ormond Street Hospital for Children, London -Honorary Senior Lecturer, King s College, London AWARDS: BJS Prize Presentation, Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland, Edinburgh, September 2001 E-poster of distinction, Association of Surgeons of Great Britain and Ireland, Bournemouth, May 2008 HESPERIS Course Diploma, European Society for Organ Transplantation October 2009 E-poster of distinction, Association of Surgeons of Great Britain and Ireland, Glasgow, May 2009 ESOT 2009 Young Investigator Award, European Society for Organ Transplantation, Paris, September 2009 Highly Commended Poster, BTS, Glasgow, 2013 Adrian Tanner Prize, Surgery Section, Royal Society of Medicine, 2013 WTC Poster of Distinction, San Francisco, 2014 Poster of Distinction, ATC, Philadelphia, 2015 American Transplant Congress Young Investigator Award, ATC, Philadelphia, 2015 Medical Physics 3D Printer Competition 2015, 1 st Prize, Guy s and St Thomas Foundation Trust The Royal College of Surgeons & Worshipful Company of Cutlers' Clarke Medal and Cutler's Prize, 2015 Norman Tanner Prize, Surgery Section, Royal Society of Medicine, 2016 MEMBERSHIP OF PROFESSIONAL BODIES: GMC Registration: , July 1997 (Full) Medecins Sans Frontieres supporter Fellow of the Association of Surgeons of Great Britain and Ireland Member of the British Medical Association Member of the Vascular Access Society

2 Member of the British Transplantation Society Member of the European Society for Organ Transplantation Member of The Transplantation Society Member of the American Society of Transplantation Member of the International Pediatric Transplant Association CLINICAL WORK: Perform multiple clinics in kidney and pancreas transplantation, live donation and vascular access surgery. Perform kidney, pancreas and paediatric transplantation as well as hand-assisted retroperitoneoscopic live donor nephrectomy, vascular access and general surgery for the renal patients (including parathyroidectomy procedures). Active member of the ABO and HLA incompatible and Pancreas Transplant programmes. Lead for Peadiatric Transplant Surgery at Great Ormond Street and Evelina Hospitals in London. EDUCATION & TEACHING: I have been responsible for the supervision and instruction of Specialist Registrars/ST, Senior House Officers/CT, Pre-registration House Officers/F1 as well as medical students since I am regularly involved in assessing surgical trainees as an Educational and Clinical Supervisor through the Intercollegiate Surgical Curriculum Programme as well as F1 doctors through NHS eportofolios. I was one of three supervisors for a successful PhD student at St George's University of London investigating effects of ischaemia reperfusion injury in gene expression in apoptosis. I am involved in the regular teaching and assessment of two Phase 3 student firms at King s College, London (Deputy Lead for one). I am also one of two supervisors for two PhDs at King s College, London and had two students who successfully received their BSc degrees over the last two years. I became an Honorary Senior Lecturer at King s College, London in May External examiner for European Diploma in Transplant Surgery, European Union of Medical Specialists European Board of Transplant Surgery National representative & internal examiner since MANAGEMENT: I successfully set up the Antibody Incompatible Transplantation at St George s Hospital and performed 10 ABO-incompatible transplants as well as two HLA-incompatible transplants. I was the Director of Transplantation from I lead multiple meetings between clinicians and clinical scientists and established our "Retrospective crossmatching" programme in April 2011 at St George s Hospital. Marked abstract for ASGBI, International Surgical Congress 2017 as well as for ESOT Corrected abstracts for the ASBGI and ESOT in the past. RESEARCH & AUDIT Transplant checklist: I created and implemented this crucial patient safety mechanism in 2013, modelled on the WHO form, that is now used immediately prior to every transplant performed at Guy's or Evelina Hospitals. 2

3 Chief investigator in a multicentre study investigating patients' views on kidney allocation in the UK. Leading this project throughout the London Transplant Units. Every year since 2013, I have been assessing the deceased donor transplant outcomes (with particular interest in Expanded Criteria Donors) at Guy s Hospital as well as presenting these findings at our annual regional audit meetings. Paediatric Audit: Lead an audit of our paediatric transplant programme at Evelina and Great Ormond Street covering 9 years and 350 paediatric transplants of which 90 were < 20kg. Revealed excellent organ & patient outcomes. Currently involved in the Laminate (Study using an implant designed to improve maturation and patency rates of arteriovenous fistulas), Humacyte (study using a bioengineered blood vessel for vascular access) and POWAR (study assessing whether antibiotics are necessary before live donor kidney nephrectomy) studies. Was the local principal investigator for ABOUT-K and National Audit of Cold Ischaemia Time studies. The former is a prospective, multi-centre, observational study, run by Birmingham and Guy's, evaluating an antigen-specific antibody removal protocol for ABO-incompatible renal transplantation in the UK. Was the local principal investigator for REPAIR, international study investigating renal protection against ischaemia-reperfusion in transplantation and recruited 38 patients. PUBLICATIONS: Published papers over the last 10 years: N Kessaris, PP Tekkis, MP Saunders, NH Boyle. Consultant views on surgeons performance tables and sequential monitoring. Bulletin of the Royal College of England 2005; Renal transplantation in identical twins in United States and United Kingdom. Kessaris N, Mukherjee D, Chandak P, Mamode N. Transplantation Dec 15;86(11): Protective effect of pentoxifylline in the kidney perfusion fluid on the transplanted kidney. Jahromi AH, Kessaris N, Sharifian M, Roozbeh J. Saudi J Kidney Dis Transpl Mar;20(2): Use of the femoral artery route for placement of temporary catheters for emergency haemodialysis when all usual central venous access sites are exhausted. Frampton AE, Kessaris N, Hossain M, Morsy M, Chemla ES. Nephrol Dial Transplant Mar;24(3): How safe is hand-assisted laparoscopic donor nephrectomy?--results of 200 live donor nephrectomies by two different techniques. Chandak P, Kessaris N, Challacombe B, Olsburgh J, Calder F, Mamode N. Nephrol Dial Transplant Jan;24(1): Mechanical complications of long-term Tesio catheters. Ndzengue A, Kessaris N, Dosani T, Mustafa N, Papalois V, Hakim NS. J Vasc Access Jan-Mar;10(1):50-4. Encapsulating Peritoneal Sclerosis. C Baker, N Kessaris, D Oliveira. Snapshots in Surgery BJS 2009;96:1252. Inferior Epigastric Vein as an Interposition Graft for Renal Transplant Artery Reconstruction. Fronek J, Hearfield H, Fassiadis N, Magrill D, Morsy M, Kessaris N Transplantation. 2010;90(10):

4 A change in opinion on surgeon's performance indicators. Maytham G, Kessaris N. Interact Cardiovasc Thorac Surg Apr;12(4): Is laparoscopic donation safe for paediatric recipients?--a study of 85 paediatric recipients comparing open and laparoscopic donor nephrectomy. Chandak P, Kessaris N, Durkan A, Owusu-Ansah N, Patel J, Veitch P, McCarthy H, Marks SD, Mamode N. Nephrol Dial Transplant Jun 28 A successful live donor kidney transplantation after large angiomyolipoma excision. Abboudi H, Chandak P, Kessaris N, Fronek J. International Journal of Surgery Case Reports. 2012; 3(12): Clinically Significant Peripancreatic Fluid Collections After Simultaneous Pancreas-Kidney Transplantation. Singh RP, Vrakas G, Hayek S, Hayek S, Anam S, Aqueel M, Olsburgh J, Calder F, Mamode N, Callaghan C, Kessaris N, Pattison J, Hilton R, Koffman G, Taylor JD, Drage MW. Transplantation May 27;95(10): Acute page kidney complicating kidney transplant artery stenting: presentation of a case and novel management. Hamidian Jahromi A, Fronek J, Kessaris N, Bydawell G, Patel U, Macphee IA. Iran J Kidney Dis Sep;7(5): HLA antibody-incompatible kidney transplantation between jehovah's witnesses--a case report. Greenberg A, Macphee I, Popoola J, Sage D, Iqbal R, Fossati N, Heap S, Morsy M, Kessaris N. Transplant Proc Jun;45(5): Successful excision of a suspected mycotic transplant renal artery patch aneurysm with renal allograft autotransplantation. Chandak P, Kessaris N, Uwechue RU, Abboudi H, Hossain M, Harris F, Jones K, Fronek J. Transplantation Feb 15;97(3):e25-6. Benaragama SK, Tymkewycz T, John BJ, Davenport A, Lindsey B, Nicol D, Olsburgh J, Drage M, Mamode N, Calder F, Taylor J, Koffman G, Kessaris N, Morsy M, Cacciola R, Puliatti C, Fernadez- Diaz S, Syed A, Hakim N, Papalois V, Fernando BS. Do we need a different organ allocation system for kidney transplants using donors after circulatory death? BMC Nephrol May 22;15:83. doi: / Hossain MA, De Souza AI, Bagul A, MacPhee IA, Kessaris N, Morsy MA. HSP70, Peroxiredoxin-3 and -6 are upregulated during renal warm ischaemia in a donation after circulatory death model. J Proteomics Aug 28;108: Karunanithy N, Uwechue R, Calder F, Mamode N, Mailli L, Chandak P, Morsy M, Fronek J, Makanjuola D, Roebuck D, Kessaris N. Endovascular Repair of Late Onset Anastomosis Site Pseudoaneurysms Complicating Renal Transplantation. J Vasc Med Surg 2014, 2:4 Couzi L, Perera R, Manook M, Barnett AN, Shaw O, Kessaris N, Marks SD, Dorling A, Mamode N. Incidence and Outcome of C4d Staining With Tubulointerstitial Inflammation in Blood Groupincompatible Kidney Transplantation. Transplantation Jul;99(7): Couzi L, Manook M, Perera R, Shaw O, Ahmed Z, Kessaris N, Dorling D, Mamode N. Difference in Outcomes after Antibody Mediated Rejection between ABO-Incompatible and Positive Crossmatch Transplantations. Transplant International Oct;28(10): Stojanovic J, Adamusiak A, Kessaris N, Chandak P, Ahmed Z, Sebire NJ, Walsh G, Jones HE, Marks 4

5 SD, Mamode N. Immune Desensitization Allows Pediatric Blood Group Incompatible Kidney Transplantation. Transplantation Jul 12 Bentall A, R Barnett AN, Braitch M, Kessaris N, McKane W, Newstead C, McHaffie G, Brown A, Griffin S, Mamode N, Briggs D, Ball S. Clinical outcomes with ABO antibody titer variability in a multicenter study of ABO-incompatible kidney transplantation in the United Kingdom. Transfusion Aug 26. Adamusiak AM, Stojanovic J, Shaw O, Vaughan R, Sebire NJ, Drage M, Kessaris N, Marks SD, Mamode N. Desensitization protocol enabling pediatric crossmatch-positive renal transplantation: successful HLA-antibody-incompatible renal transplantation of two highly sensitized children. Pediatr Nephrol Sep 1. Chandak P, Kessaris N, Callaghan CJ, Calder F, Stojanovic J, Olsburgh J, Drage M, Hume-Smith H, Ahmed Z, Adamusiak A, Roebuck D, Forman C, Marks SD, Mamode N. Insights in Transplanting Complex Paediatric Renal Recipients With Vascular Anomalies. Transplantation Jan 17 Manook M, Koeser L, Ahmed Z, Robb M, Johnson R, Shaw O, Kessaris N, Dorling A, Mamode N. Post-listing survival for highly sensitised patients on the UK kidney transplant waiting list: a matched cohort analysis. Lancet Feb 18;389(10070): Mittal S, Adamusiak A, Horsfield C, Loukopoulos I, Karydis N, Kessaris N, Drage M, Olsburgh J, Watson CJ, Callaghan CJ. A Re-evaluation of Discarded Deceased Donor Kidneys in the UK: Are Usable Organs Still Being Discarded? Transplantation Jul;101(7): Published chapters: N.Kessaris, V Papalois, R Canelo, N Hakim. (2010) Live Kidney Transplantation (pp39-63), Living Related Transplantation, World Scientific. N Kessaris, N Mamode. (2012) Antibody incompatible kidney transplantation (pp ). In: I MacPhee and J Fronek (eds), Handbook of Renal and Pancreatic Transplantation, Wiley-Blackwell. J Fronek, N Kessaris. (2012) Live Donor Nephrectomy (pp ). In: I MacPhee and J Fronek (eds), Handbook of Renal and Pancreatic Transplantation, Wiley-Blackwell. J Fronek, N Kessaris. (2012) Living donor renal transplantation (pp ). In: I MacPhee and J Fronek (eds), Handbook of Renal and Pancreatic Transplantation, Wiley-Blackwell. N Kessaris, N S Hakim. (2012) Renal Transplantation (pp83-110). In: N S Hakim (ed), Introduction to Organ Transplantation, 2 nd Edition, Imperial College Press. E-Chapter on Long term outcomes after living donor nephrectomy for the ESOT education platform,

6 Personal Statement I have been an ESOT member for more than 10 years. With my experience in all aspects of Adult and Paediatric Renal Transplantation, I would like to make EKITA more accessible to its members in order to promote its goals of exchange of scientific information, views and ideas in providing the best service for patients in Europe requiring kidney transplantation. If elected as EKITA Board Member, I would first like to create a map of all European Kidney Transplant Centres where all units will be visible. Then, I would like to promote the exchange of doctors, nurses and other allied members for short periods between different units to learn from each other s experiences. These actions will promote best practice, exchange of ideas and collaboration.