LOS ANGELES COUNTY DEPARTMENT OF HEALTH SERVICES HIV EPIDEMIOLOGY PROGRAM

Transcription

1 DEPARTMENT OF HEALTH SERVICES HIV EPIDEMIOLOGY PROGRAM ADVANCED HIV DISEASE (AIDS) QUARTERLY SURVEILLANCE SUMMARY Cases Reported as of March 31, 2001 Issued April 15, S. Commonwealth Ave., Suite 1920 Los Angeles, CA (Phone) (213) (Fax) (213)

2 HIV Epidemiology Program GORDON BUNCH, M.A., Acting Director 600 South Commonwealth Avenue, Suite 1920 Los Angeles, California TEL (213) FAX (213) April 15, 2001 Dear Colleague: Enclosed you will find the April 15, 2001 issue of the Advanced HIV Disease (AIDS) Quarterly Surveillance Summary for Los Angeles County. As of March 31, 2001, 42,572 persons with AIDS were reported in Los Angeles County. As of January 1, 2001, our Data Acquisition and Data Analysis units have been combined into one unit, HIV/AIDS Surveillance. Mi Suk Yu-Harlan, Epidemiologist, is the Chief of the HIV/AIDS Surveillance Unit. This unit is presently responsible for the collection and analysis of local AIDS case data and the duties of this unit will expand to include HIV surveillance when California adopts HIV reporting in the near future. Within the HIV/AIDS Surveillance Unit, AIDS surveillance activities are conducted by Linda Cardenas-Ochoa, PHN; Luisa Chong, PHN; Robert Simcik, PHI; Napoleon Suarez; and Anita Williams, PHN. For questions regarding AIDS surveillance data, please call the phone number listed above and ask for Virginia Hu, Zhijuan Sheng, or Mi Suk Yu-Harlan. Thank you for your continued interest in our data and we appreciate the support of health care providers who contribute greatly to the timely, accurate and complete reporting of AIDS in Los Angeles County. Data presented in this report and other HIV Epidemiology Program data are available on our webpage at If you need additional copies of this Quarterly Surveillance Summary or have questions about confidential AIDS case reporting, please contact our office. Sincerely, Gordon Bunch, M.A. Acting Director GB:MSY:mt

3 Los Angeles County Department of Health Services HIV Epidemiology Program Advanced HIV Disease (AIDS) Quarterly Surveillance Summary, January-March, 2001 Los Angeles County 1 New cases reported this quarter* 362 New cases reported year-to-date* 362 Deaths reported this quarter* 115 Deaths reported year-to-date* 115 Cumulative cases 42,572 Cumulative deaths 26,669 Living cases 15,903 Cumulative case-fatality rate 63% California 2 Cumulative cases 120,802 Cumulative deaths 73,992 Living cases 46,810 Cumulative case-fatality rate 61% United States 3 Cumulative cases 753,907 Cumulative deaths 438,795 Living cases 315,112 Cumulative case-fatality rate 58% 1 Includes all cases reported to the HIV Epidemiology Program as of March 31, California Office of AIDS. Preliminary California AIDS Update, March 31, Centers for Disease Control and Prevention. HIV/AIDS Surveillance Report, June 2000, Vol.12, No.1. * Totals may not be consistent with previous quarterly reports due to periodic updates of the database, including the deletion of duplicate cases and the reclassification of previously reported AIDS cases as non-cases. 1

4 FIGURE 1. CASES OF ADVANCED HIV DISEASE (AIDS) AND DEATHS BY YEAR OF DIAGNOSIS Cases 4500 Dead 4000 Alive** * Year of Diagnosis * Data are provisional for ** Alive includes vital status unknown. TABLE 1. CASES, DEATHS AND CASE-FATALITY RATES OF ADVANCED HIV DISEASE (AIDS) BY YEAR OF DIAGNOSIS, REPORTED BY MARCH 31, 2001, Year of Diagnosis Cases Deaths (1) Case-fatality Rate (2) % 95% 91% 88% 84% 76% 65% 52% 34% 22% 18% 15% 13% 10% Total (3) % 1. Deaths are reported by the year of AIDS diagnosis. 2. Data are provisional due to reporting delay. 3. Total includes 3375 cases that were diagnosed before

5 TABLE 2. CUMULATIVE CASES OF ADVANCED HIV DISEASE (AIDS) BY GENDER, AGE GROUP AND RACE/ETHNICITY REPORTED BY MARCH 31, 2001 Race/Ethnicity Age at Diagnosis White Black Hispanic Asian (1) AI/AN (2) Total (3) (years) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) MALE <13 26 ( 0) 46 ( 1) 56 ( 1) 2 ( 0) 1 ( 1) 131 ( 0) ( 0) 28 ( 0) 61 ( 1) 3 ( 0) 1 ( 1) 119 ( 0) ( 12) 1225 ( 17) 2480 ( 23) 106 ( 14) 30 ( 29) 6334 ( 16) ( 45) 3308 ( 45) 5030 ( 46) 320 ( 42) 47 ( 45) ( 45) ( 28) 1953 ( 27) 2265 ( 21) 246 ( 32) 16 ( 15) ( 26) ( 11) 603 ( 8) 727 ( 7) 72 ( 9) 7 ( 7) 3566 ( 9) ( 4) 186 ( 3) 255 ( 2) 17 ( 2) 3 ( 3) 1195 ( 3) Male subtotal [% of subtotal] [ 51] [ 19] [ 28] [ 2] [ 0] [100] FEMALE <13 17 ( 2) 33 ( 3) 51 ( 5) 3 ( 5) 0 ( 0) 104 ( 3) ( 1) 13 ( 1) 20 ( 2) 2 ( 3) 0 ( 0) 42 ( 1) ( 19) 254 ( 22) 279 ( 26) 9 ( 14) 2 ( 13) 683 ( 22) ( 37) 462 ( 40) 383 ( 35) 16 ( 24) 5 ( 33) 1147 ( 37) ( 22) 276 ( 24) 201 ( 18) 19 ( 29) 5 ( 33) 670 ( 22) ( 9) 93 ( 8) 109 ( 10) 13 ( 20) 2 ( 13) 284 ( 9) ( 9) 34 ( 3) 51 ( 5) 4 ( 6) 1 ( 7) 160 ( 5) Female subtotal [% of subtotal] [ 24] [ 38] [ 35] [ 2] [ 0] [100] Total [% of total] [ 49] [ 20] [ 28] [ 2] [ 0] [100] 1. Includes <5 Burmese, 19 Cambodian, 74 Chinese, 254 Filipino, 14 Guamanian, 26 Hawaiian, 6 Indian, 10 Indonesian, 109 Japanese, 33 Korean, <5 Loatian, 8 Malayan, <5 N Marianan, 5 Pacific Islander, <5 Pakistani, 26 Samoan, <5 Singaporean, <5 Sri Lankan, <5 Tahitian, 18 Taiwanese, 56 Thai, <5 Tongan, and 56 Vietnamese; 89 are of unknown Asian ethnicity. 2. AI/AN=American Indian/Alaska Native. 3. Includes 114 males and 6 females whose race/ethnicity is unknown. 3

6 TABLE 3. CUMULATIVE ADULT/ADOLESCENT CASES OF ADVANCED HIV DISEASE (AIDS) BY GENDER, EXPOSURE CATEGORY AND RACE/ETHNICITY REPORTED BY MARCH 31, 2001 Race/Ethnicity Adult/Adolescent White Black Hispanic Asian AI/AN (2) Total (3) Exposure Category (1) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) MALE Male-male sexual contact ( 85) 4776 ( 65) 7671 ( 71) 629 ( 82) 79 ( 76) ( 77) Injection drug user (IDU) 684 ( 3) 824 ( 11) 664 ( 6) 10 ( 1) 5 ( 5) 2191 ( 6) Male-male sexual contact/idu 1430 ( 7) 654 ( 9) 570 ( 5) 23 ( 3) 12 ( 12) 2691 ( 7) Hemophilia or coagulation disorder 87 ( 0) 22 ( 0) 41 ( 0) 8 ( 1) 0 ( 0) 161 ( 0) Heterosexual contact (4) 126 ( 1) 182 ( 2) 241 ( 2) 7 ( 1) 0 ( 0) 558 ( 1) Transfusion recipient 138 ( 1) 39 ( 1) 90 ( 1) 18 ( 2) 1 ( 1) 287 ( 1) Other/Undetermined 645 ( 3) 806 ( 11) 1541 ( 14) 69 ( 9) 7 ( 7) 3075 ( 8) Male subtotal [% of subtotal] [ 51] [ 19] [ 27] [ 2] [ 0] [100] FEMALE Injection drug user (IDU) 242 ( 33) 343 ( 30) 163 ( 16) 7 ( 11) 6 ( 40) 765 ( 26) Hemophilia or coagulation disorder 7 ( 1) 2 ( 0) 2 ( 0) 0 ( 0) 0 ( 0) 11 ( 0) Heterosexual contact (4) 309 ( 43) 488 ( 43) 542 ( 52) 30 ( 48) 5 ( 33) 1375 ( 46) Transfusion recipient 75 ( 10) 46 ( 4) 98 ( 9) 15 ( 24) 0 ( 0) 234 ( 8) Other/Undetermined 94 ( 13) 253 ( 22) 238 ( 23) 11 ( 17) 4 ( 27) 601 ( 20) Female subtotal [% of subtotal] [ 24] [ 38] [ 35] [ 2] [ 1] [100] Total [% of total] [ 50] [ 20] [ 28] [ 2] [ 0] [100] 1. Exposure categories are ordered hierarchically. Except for the combination listed, cases with multiple exposure categories are included in the category listed first. 2. AI/AN=American Indian/Alaska Native. 3. Includes 114 males and 6 females whose race/ethnicity is unknown. 4. Heterosexual contact with a person who is HIV-infected or at increased risk for HIV. 4

7 TABLE 4. ANNUAL ADULT/ADOLESCENT CASES OF ADVANCED HIV DISEASE (AIDS) AND RATES PER 100,000 BY GENDER, YEAR OF DIAGNOSIS AND RACE/ETHNICITY REPORTED BY MARCH 31, 2001 Race/Ethnicity White Black Hispanic Other Total (1) Year of Diagnosis No. (Rate) No. (Rate) No. (Rate) No. (Rate) No. (Rate) MALE (131) 755 (227) 1048 ( 77) 110 ( 28) 3898 (109) (119) 701 (213) 1070 ( 77) 76 ( 19) 3632 (100) (107) 701 (215) 988 ( 69) 89 ( 21) 3374 ( 92) ( 97) 593 (183) 987 ( 67) 78 ( 18) 3092 ( 83) ( 73) 490 (152) 803 ( 53) 63 ( 14) 2417 ( 64) ( 44) 422 (132) 713 ( 46) 51 ( 11) 1814 ( 48) ( 37) 366 (116) 647 ( 40) 45 ( 9) 1590 ( 41) ( 30) 281 ( 90) 585 ( 35) 47 ( 9) 1333 ( 34) 2000 (2) 299 ( 21) 223 ( 71) 462 ( 28) 22 ( 4) 1007 ( 26) Male subtotal(3) FEMALE ( 5) 97 ( 25) 82 ( 6) 6 ( 1) 263 ( 7) ( 5) 106 ( 27) 113 ( 9) 2 ( 0) 300 ( 8) ( 3) 140 ( 37) 100 ( 7) 7 ( 2) 297 ( 8) ( 5) 128 ( 34) 128 ( 9) 10 ( 2) 341 ( 9) ( 4) 99 ( 26) 116 ( 8) 7 ( 1) 278 ( 7) ( 3) 117 ( 32) 90 ( 6) 8 ( 2) 261 ( 7) ( 2) 72 ( 20) 83 ( 5) 5 ( 1) 194 ( 5) ( 2) 79 ( 22) 64 ( 4) 4 ( 1) 182 ( 5) 2000 (2) 27 ( 2) 67 ( 18) 75 ( 5) 4 ( 1) 173 ( 4) Female subtotal(3) Total (3) Total includes cases whose race/ethnicity is unknown. 2. Data are provisional due to reporting delay. 3. Includes cases diagnosed prior to

8 TABLE 5. ADULT/ADOLESCENT CASES OF ADVANCED HIV DISEASE (AIDS) BY GENDER, EXPOSURE CATEGORY AND YEAR OF DIAGNOSIS, REPORTED BY MARCH 31, 2001, LA COUNTY Year of Diagnosis Cumulative Adult/Adolescent (2) Total (3) Exposure Category (1) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) MALE Male-male sexual contact 3093 ( 79) 2825 ( 78) 2596 ( 77) 2340 ( 76) 1781 ( 74) 1183 ( 65) 1004 ( 63) 846 ( 63) 583 ( 58) ( 77) Injection drug user (IDU) 252 ( 6) 257 ( 7) 248 ( 7) 183 ( 6) 161 ( 7) 129 ( 7) 98 ( 6) 75 ( 6) 63 ( 6) 2191 ( 6) Male-male sexual contact/idu 267 ( 7) 272 ( 7) 207 ( 6) 194 ( 6) 136 ( 6) 98 ( 5) 85 ( 5) 58 ( 4) 41 ( 4) 2691 ( 7) Hemophilia or coagulation disorder 20 ( 1) 13 ( 0) 17 ( 1) 12 ( 0) 4 ( 0) 10 ( 1) 1 ( 0) 2 ( 0) 2 ( 0) 161 ( 0) Heterosexual contact (4) 53 ( 1) 47 ( 1) 45 ( 1) 66 ( 2) 47 ( 2) 61 ( 3) 56 ( 4) 42 ( 3) 26 ( 3) 558 ( 1) Transfusion recipient 27 ( 1) 17 ( 0) 18 ( 1) 15 ( 0) 14 ( 1) 7 ( 0) 2 ( 0) 3 ( 0) 3 ( 0) 287 ( 1) Other/Undetermined 186 ( 5) 201 ( 6) 243 ( 7) 282 ( 9) 274 ( 11) 326 ( 18) 344 ( 22) 307 ( 23) 289 ( 29) 3075 ( 8) Male subtotal [% of subtotal] [ 10] [ 9] [ 9] [ 8] [ 6] [ 5] [ 4] [ 3] [ 3] [100] FEMALE Injection drug user (IDU) 87 ( 33) 73 ( 24) 81 ( 27) 90 ( 26) 70 ( 25) 66 ( 25) 37 ( 19) 36 ( 20) 26 ( 15) 765 ( 26) Hemophilia or coagulation disorder 0 ( 0) 2 ( 1) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 1 ( 1) 0 ( 0) 0 ( 0) 11 ( 0) Heterosexual contact (4) 130 ( 49) 159 ( 53) 154 ( 52) 185 ( 54) 139 ( 50) 121 ( 46) 86 ( 44) 80 ( 44) 64 ( 37) 1375 ( 46) Transfusion recipient 17 ( 6) 26 ( 9) 21 ( 7) 15 ( 4) 9 ( 3) 6 ( 2) 3 ( 2) 1 ( 1) 1 ( 1) 234 ( 8) Other/Undetermined 29 ( 11) 40 ( 13) 41 ( 14) 51 ( 15) 60 ( 22) 68 ( 26) 67 ( 35) 65 ( 36) 82 ( 47) 601 ( 20) Female subtotal [% of subtotal] [ 9] [ 10] [ 10] [ 11] [ 9] [ 9] [ 6] [ 6] [ 6] [100] Total [% of total] [ 10] [ 9] [ 9] [ 8] [ 6] [ 5] [ 4] [ 4] [ 3] [100] 1. Exposure categories are ordered hierarchically. Cases with multiple exposure categories are included in the category listed first. 2. Data are provisional due to reporting delay. 3. Includes cases diagnosed prior to Heterosexual contact with a person who is HIV-infected or at increased risk for HIV. 6

9 TABLE 6. WHITE ADULT/ADOLESCENT CASES OF ADVANCED HIV DISEASE (AIDS) BY GENDER, EXPOSURE CATEGORY AND YEAR OF DIAGNOSIS, REPORTED BY MARCH 31, 2001, LA COUNTY Year of Diagnosis Cumulative Adult/Adolescent (2) Total (3) Exposure Category (1) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) MALE Male-male sexual contact 1699 ( 86) 1489 ( 84) 1320 ( 83) 1178 ( 83) 866 ( 82) 470 ( 75) 389 ( 73) 308 ( 74) 217 ( 73) ( 85) Injection drug user (IDU) 75 ( 4) 88 ( 5) 79 ( 5) 52 ( 4) 49 ( 5) 38 ( 6) 32 ( 6) 20 ( 5) 13 ( 4) 684 ( 3) Male-male sexual contact/idu 131 ( 7) 128 ( 7) 103 ( 7) 92 ( 6) 72 ( 7) 45 ( 7) 38 ( 7) 32 ( 8) 22 ( 7) 1430 ( 7) Hemophilia or coagulation disorder 9 ( 0) 4 ( 0) 7 ( 0) 8 ( 1) 2 ( 0) 6 ( 1) 1 ( 0) 1 ( 0) 1 ( 0) 87 ( 0) Heterosexual contact (4) 13 ( 1) 14 ( 1) 8 ( 1) 15 ( 1) 5 ( 0) 10 ( 2) 9 ( 2) 12 ( 3) 2 ( 1) 126 ( 1) Transfusion recipient 11 ( 1) 5 ( 0) 5 ( 0) 5 ( 0) 2 ( 0) 2 ( 0) 0 ( 0) 2 ( 0) 0 ( 0) 138 ( 1) Other/Undetermined 38 ( 2) 46 ( 3) 60 ( 4) 74 ( 5) 63 ( 6) 56 ( 9) 61 ( 12) 44 ( 11) 44 ( 15) 645 ( 3) Male subtotal [% of subtotal] [ 10] [ 9] [ 8] [ 7] [ 5] [ 3] [ 3] [ 2] [ 1] [100] FEMALE Injection drug user (IDU) 35 ( 45) 27 ( 35) 24 ( 48) 21 ( 28) 23 ( 42) 16 ( 35) 10 ( 30) 13 ( 38) 8 ( 30) 242 ( 33) Hemophilia or coagulation disorder 0 ( 0) 1 ( 1) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 7 ( 1) Heterosexual contact (4) 37 ( 47) 37 ( 47) 18 ( 36) 37 ( 50) 23 ( 42) 24 ( 52) 17 ( 52) 17 ( 50) 8 ( 30) 309 ( 43) Transfusion recipient 4 ( 5) 3 ( 4) 4 ( 8) 4 ( 5) 0 ( 0) 1 ( 2) 1 ( 3) 0 ( 0) 0 ( 0) 75 ( 10) Other/Undetermined 2 ( 3) 10 ( 13) 4 ( 8) 12 ( 16) 9 ( 16) 5 ( 11) 5 ( 15) 4 ( 12) 11 ( 41) 94 ( 13) Female subtotal [% of subtotal] [ 11] [ 11] [ 7] [ 10] [ 8] [ 6] [ 5] [ 5] [ 4] [100] Total [% of total] [ 10] [ 9] [ 8] [ 7] [ 5] [ 3] [ 3] [ 2] [ 2] [100] 1. Exposure categories are ordered hierarchically. Cases with multiple exposure categories are included in the category listed first. 2. Data are provisional due to reporting delay. 3. Includes cases diagnosed prior to Heterosexual contact with a person who is HIV-infected or at increased risk for HIV. 7

10 TABLE 7. BLACK ADULT/ADOLESCENT CASES OF ADVANCED HIV DISEASE (AIDS) BY GENDER, EXPOSURE CATEGORY AND YEAR OF DIAGNOSIS, REPORTED BY MARCH 31, 2001, LA COUNTY Year of Diagnosis Cumulative Adult/Adolescent (2) Total (3) Exposure Category (1) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) MALE Male-male sexual contact 500 ( 66) 480 ( 68) 455 ( 65) 378 ( 64) 297 ( 61) 239 ( 57) 216 ( 59) 171 ( 61) 110 ( 49) 4776 ( 65) Injection drug user (IDU) 93 ( 12) 92 ( 13) 97 ( 14) 64 ( 11) 66 ( 13) 51 ( 12) 31 ( 8) 22 ( 8) 21 ( 9) 824 ( 11) Male-male sexual contact/idu 74 ( 10) 58 ( 8) 54 ( 8) 57 ( 10) 30 ( 6) 23 ( 5) 25 ( 7) 10 ( 4) 9 ( 4) 654 ( 9) Hemophilia or coagulation disorder 3 ( 0) 2 ( 0) 2 ( 0) 1 ( 0) 1 ( 0) 0 ( 0) 0 ( 0) 1 ( 0) 0 ( 0) 22 ( 0) Heterosexual contact (4) 24 ( 3) 10 ( 1) 18 ( 3) 18 ( 3) 17 ( 3) 21 ( 5) 11 ( 3) 10 ( 4) 10 ( 4) 182 ( 2) Transfusion recipient 2 ( 0) 2 ( 0) 6 ( 1) 3 ( 1) 1 ( 0) 1 ( 0) 1 ( 0) 0 ( 0) 0 ( 0) 39 ( 1) Other/Undetermined 59 ( 8) 57 ( 8) 69 ( 10) 72 ( 12) 78 ( 16) 87 ( 21) 82 ( 22) 67 ( 24) 73 ( 33) 806 ( 11) Male subtotal [% of subtotal] [ 10] [ 10] [ 10] [ 8] [ 7] [ 6] [ 5] [ 4] [ 3] [100] FEMALE Injection drug user (IDU) 33 ( 34) 26 ( 25) 39 ( 28) 44 ( 34) 29 ( 29) 33 ( 28) 14 ( 19) 16 ( 20) 14 ( 21) 343 ( 30) Hemophilia or coagulation disorder 0 ( 0) 1 ( 1) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 2 ( 0) Heterosexual contact (4) 49 ( 51) 54 ( 51) 66 ( 47) 64 ( 50) 42 ( 42) 53 ( 45) 28 ( 39) 29 ( 37) 22 ( 33) 488 ( 43) Transfusion recipient 3 ( 3) 7 ( 7) 8 ( 6) 3 ( 2) 2 ( 2) 2 ( 2) 1 ( 1) 1 ( 1) 0 ( 0) 46 ( 4) Other/Undetermined 12 ( 12) 18 ( 17) 27 ( 19) 17 ( 13) 26 ( 26) 29 ( 25) 29 ( 40) 33 ( 42) 31 ( 46) 253 ( 22) Female subtotal [% of subtotal] [ 9] [ 9] [ 12] [ 11] [ 9] [ 10] [ 6] [ 7] [ 6] [100] Total [% of total] [ 10] [ 10] [ 10] [ 9] [ 7] [ 6] [ 5] [ 4] [ 3] [100] 1. Exposure categories are ordered hierarchically. Cases with multiple exposure categories are included in the category listed first. 2. Data are provisional due to reporting delay. 3. Includes cases diagnosed prior to Heterosexual contact with a person who is HIV-infected or at increased risk for HIV. 8

11 TABLE 8. HISPANIC ADULT/ADOLESCENT CASES OF ADVANCED HIV DISEASE (AIDS) BY GENDER, EXPOSURE CATEGORY AND YEAR OF DIAGNOSIS, REPORTED BY MARCH 31, 2001, LA COUNTY Year of Diagnosis Cumulative Adult/Adolescent (2) Total (3) Exposure Category (1) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) MALE Male-male sexual contact 791 ( 75) 781 ( 73) 736 ( 74) 711 ( 72) 568 ( 71) 436 ( 61) 365 ( 56) 336 ( 57) 241 ( 52) 7671 ( 71) Injection drug user (IDU) 81 ( 8) 77 ( 7) 67 ( 7) 66 ( 7) 43 ( 5) 39 ( 5) 34 ( 5) 33 ( 6) 29 ( 6) 664 ( 6) Male-male sexual contact/idu 59 ( 6) 82 ( 8) 48 ( 5) 41 ( 4) 30 ( 4) 28 ( 4) 20 ( 3) 15 ( 3) 8 ( 2) 570 ( 5) Hemophilia or coagulation disorder 5 ( 0) 6 ( 1) 7 ( 1) 3 ( 0) 0 ( 0) 4 ( 1) 0 ( 0) 0 ( 0) 1 ( 0) 41 ( 0) Heterosexual contact (4) 15 ( 1) 20 ( 2) 18 ( 2) 32 ( 3) 25 ( 3) 29 ( 4) 36 ( 6) 19 ( 3) 13 ( 3) 241 ( 2) Transfusion recipient 12 ( 1) 9 ( 1) 7 ( 1) 5 ( 1) 11 ( 1) 3 ( 0) 1 ( 0) 0 ( 0) 3 ( 1) 90 ( 1) Other/Undetermined 85 ( 8) 95 ( 9) 105 ( 11) 129 ( 13) 126 ( 16) 174 ( 24) 191 ( 30) 182 ( 31) 167 ( 36) 1541 ( 14) Male subtotal [% of subtotal] [ 10] [ 10] [ 9] [ 9] [ 7] [ 7] [ 6] [ 5] [ 4] [100] FEMALE Injection drug user (IDU) 18 ( 22) 19 ( 17) 17 ( 17) 22 ( 17) 15 ( 13) 15 ( 17) 12 ( 14) 6 ( 9) 4 ( 5) 163 ( 16) Hemophilia or coagulation disorder 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 1 ( 1) 0 ( 0) 0 ( 0) 2 ( 0) Heterosexual contact (4) 39 ( 48) 67 ( 59) 67 ( 67) 78 ( 61) 72 ( 62) 42 ( 47) 38 ( 46) 31 ( 48) 31 ( 41) 542 ( 52) Transfusion recipient 10 ( 12) 15 ( 13) 7 ( 7) 7 ( 5) 7 ( 6) 2 ( 2) 1 ( 1) 0 ( 0) 1 ( 1) 98 ( 9) Other/Undetermined 15 ( 18) 12 ( 11) 9 ( 9) 21 ( 16) 22 ( 19) 31 ( 34) 31 ( 37) 27 ( 42) 39 ( 52) 238 ( 23) Female subtotal [% of subtotal] [ 8] [ 11] [ 10] [ 12] [ 11] [ 9] [ 8] [ 6] [ 7] [100] Total [% of total] [ 10] [ 10] [ 9] [ 9] [ 8] [ 7] [ 6] [ 5] [ 5] [100] 1. Exposure categories are ordered hierarchically. Cases with multiple exposure categories are included in the category listed first. 2. Data are provisional due to reporting delay. 3. Includes cases diagnosed prior to Heterosexual contact with a person who is HIV-infected or at increased risk for HIV. 9

12 TABLE 9. CUMULATIVE PEDIATRIC CASES OF ADVANCED HIV DISEASE (AIDS) BY EXPOSURE CATEGORY AND RACE/ETHNICITY REPORTED BY MARCH 31, 2001 Race/Ethnicity Pediatric (<13 years) White Black Hispanic Other Total Exposure Category (1) No. (%) No. (%) No. (%) No. (%) No. (%) Hemophilia/coagulation disorder 3 ( 7) 0 ( 0) 3 ( 3) 1 ( 17) 7 ( 3) Mother with/at risk for HIV 20 ( 47) 64 ( 81) 77 ( 72) 1 ( 17) 162 ( 69) Transfusion recipient 20 ( 47) 13 ( 16) 25 ( 23) 4 ( 67) 62 ( 26) Other/Undetermined 0 ( 0) 2 ( 3) 2 ( 2) 0 ( 0) 4 ( 2) Total [% of total] [ 18] [ 34] [ 46] [ 3] [100] 1. Exposure categories are ordered hierarchically. Except for the combination listed, cases with multiple exposure categories are included in the category listed first. TABLE 10. PEDIATRIC CASES OF ADVANCED HIV DISEASE (AIDS) BY EXPOSURE CATEGORY AND YEAR OF DIAGNOSIS REPORTED BY MARCH 31, 2001 Year of Diagnosis Before Pediatric (<13 years) (2) Exposure Category (1) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) Hemophilia/coagulation disorder 7 ( 3) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) Mother with/at risk for HIV 141 ( 66) 9 (100) 6 (100) 3 (100) 1 (100) 2 ( 67) Transfusion recipient 62 ( 29) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) Other/Undetermined 3 ( 1) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 1 ( 33) Total [% of total] [ 91] [ 4] [ 3] [ 1] [ 0] [ 1] 1. Exposure categories are ordered hierarchically. Except for the combination listed, cases with multiple exposure categories are included in the category listed first. 2. Data are provisional due to reporting delay. 10

13 TABLE 11. PEDIATRIC CASES OF ADVANCED HIV DISEASE (AIDS) BY RACE/ETHNICITY AND YEAR OF DIAGNOSIS REPORTED BY MARCH 31, 2001 Year of Diagnosis Before Pediatric (<13 years) (1) Race/Ethnicity No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) White 42 ( 20) 0 ( 0) 1 ( 17) 0 ( 0) 0 ( 0) 0 ( 0) Black 67 ( 31) 5 ( 56) 3 ( 50) 2 ( 67) 1 (100) 1 ( 33) Hispanic 98 ( 46) 4 ( 44) 2 ( 33) 1 ( 33) 0 ( 0) 2 ( 67) Other 6 ( 3) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) 0 ( 0) Total [% of total] [ 91] [ 4] [ 3] [ 1] [ 0] [ 1] 1. Data are provisional due to reporting delay. 11

14 TABLE 12. CUMULATIVE ADULT/ADOLESCENT CASES OF ADVANCED HIV DISEASE (AIDS) BY GENDER, RACE/ETHNICITY AND DEFINITION CATEGORY REPORTED BY MARCH 31, 2001 Definition Category (1) Pre Definition(4) Total Race/Ethnicity Definition(2) Definition(3) Clinical Criteria CD4 Criteria No. (%) No. (%) No. (%) No. (%) No. (%) MALE White ( 57) 2591 ( 49) 136 ( 21) 5191 ( 44) ( 51) Black 3411 ( 16) 1172 ( 22) 234 ( 37) 2486 ( 21) 7303 ( 19) Hispanic 5229 ( 24) 1433 ( 27) 246 ( 38) 3910 ( 33) ( 27) Asian 430 ( 2) 95 ( 2) 15 ( 2) 224 ( 2) 764 ( 2) AI/AN (5) 43 ( 0) 12 ( 0) 7 ( 1) 42 ( 0) 104 ( 0) Male subtotal (6) [% of subtotal] [ 55] [ 14] [ 2] [ 30] [100] FEMALE White 302 ( 27) 112 ( 26) 15 ( 15) 298 ( 22) 727 ( 24) Black 401 ( 36) 150 ( 35) 54 ( 55) 527 ( 39) 1132 ( 38) Hispanic 375 ( 34) 148 ( 34) 21 ( 21) 499 ( 37) 1043 ( 35) Asian 20 ( 2) 13 ( 3) 4 ( 4) 26 ( 2) 63 ( 2) AI/AN (5) 4 ( 0) 4 ( 1) 1 ( 1) 6 ( 0) 15 ( 1) Female subtotal (6) [% of subtotal] [ 37] [ 14] [ 3] [ 45] [100] Total [% of total] [ 53] [ 14] [ 2] [ 31] [100] 1. Definition categories are ordered hierarchically. 2. MMWR 1985; 34: MMWR 1987; 36[suppl.No.1s]:1s-15s. This revision added HIV encephalopathy, wasting syndrome, and presumptive diagnosis of certain AIDS indicator-conditions. 4. MMWR 1992; 41[suppl.No.RR-17]:1-19. Clinical criteria includes pulmonary tuberculosis, recurrent pneumonia, and invasive cervical cancer. CD4 criteria includes persons with less than 200 CD4+ T-lymphocytes/ul or a CD4+ T-lymphocyte percent less than 14, and no AIDS indicator clinical conditions. 5. AI/AN=American Indian/Alaska Native. 6. Includes 114 males and 6 females whose race/ethnicity is unknown. 12

15 TABLE 13. CUMULATIVE ADULT/ADOLESCENT AND PEDIATRIC CASES OF INJECTION DRUG-ASSOCIATED ADVANCED HIV DISEASE (AIDS) BY GENDER, EXPOSURE CATEGORY AND RACE/ETHNICITY REPORTED BY MARCH 31, 2001 Race/Ethnicity White Black Hispanic Other Total (2) Exposure Category (1) No. (%) No. (%) No. (%) No. (%) No. (%) ADULT/ADOLESCENT Male Injection drug user (IDU) 684 ( 32) 824 ( 53) 664 ( 50) 15 ( 29) 2191 ( 43) Male-male sexual contact/idu 1430 ( 66) 654 ( 42) 570 ( 43) 35 ( 67) 2691 ( 53) Sex with IDU 57 ( 3) 83 ( 5) 98 ( 7) 2 ( 4) 241 ( 5) Adult male subtotal [% of subtotal] [ 42] [ 30] [ 26] [ 1] [100] Female Injection drug user (IDU) 242 ( 74) 343 ( 73) 163 ( 62) 13 ( 81) 765 ( 71) Sex with IDU 85 ( 26) 125 ( 27) 98 ( 38) 3 ( 19) 311 ( 29) Adult female subtotal [% of subtotal] [ 30] [ 43] [ 24] [ 1] [100] Adult subtotal [% of subtotal] [ 40] [ 33] [ 26] [ 1] [100] PEDIATRIC (<13 YEARS) Mother was IDU 9 ( 64) 17 ( 68) 7 ( 33) 0 ( 0) 33 ( 54) Mother had sex with IDU 5 ( 36) 8 ( 32) 14 ( 67) 1 (100) 28 ( 46) Pediatric subtotal [% of subtotal] [ 23] [ 41] [ 34] [ 2] [100] Total [% of total] [ 40] [ 33] [ 26] [ 1] [100] 1. Exposure categories are ordered hierarchically. Except for the combination listed, cases with multiple exposure categories are included in the category listed first. 2. Total includes cases whose race/ethnicity is unknown. 13

16 TABLE 14. ADULT/ADOLESCENT ADVANCED HIV DISEASE (AIDS) INDICATOR CONDITIONS AT TIME OF AIDS DIAGNOSIS (1) BY GENDER REPORTED BY MARCH 31, 2001 Gender Male Female Total Indicator Condition (2) No. (%) No. (%) No. (%) Candidiasis of bronchi, trachea, or lungs 154 ( 0) 17 ( 1) 171 ( 0) Candidiasis of esophagus 902 ( 2) 130 ( 4) 1032 ( 2) Carcinoma, invasive cervical. (.) 16 ( 1) 16 ( 0) Coccidioidomycosis, disseminated or extrapulmonary 62 ( 0) 4 ( 0) 66 ( 0) Cryptococcosis, extrapulmonary 726 ( 2) 49 ( 2) 775 ( 2) Cryptosporidiosis, chronic intestinal 371 ( 1) 14 ( 0) 385 ( 1) Cytomegalovirus disease other than retinitis 621 ( 2) 45 ( 2) 666 ( 2) Cytomegalovirus retinitis 418 ( 1) 30 ( 1) 448 ( 1) HIV encephalopathy 437 ( 1) 33 ( 1) 470 ( 1) Herpes simplex: chronic ulcers, pneumonitis or esophagitis 522 ( 1) 48 ( 2) 570 ( 1) Histoplasmosis, disseminated or extrapulmonary 73 ( 0) 8 ( 0) 81 ( 0) Isosporiasis, chronic intestinal 76 ( 0) 5 ( 0) 81 ( 0) Kaposi's sarcoma 1827 ( 5) 12 ( 0) 1839 ( 4) Lymphoma, Burkitt's 105 ( 0) 7 ( 0) 112 ( 0) Lymphoma, immunoblastic 357 ( 1) 17 ( 1) 374 ( 1) Lymphoma, primary in brain 63 ( 0) 2 ( 0) 65 ( 0) Mycobacterium avium or M. kansasii, disseminated 435 ( 1) 24 ( 1) 459 ( 1) M. tuberculosis, pulmonary 981 ( 2) 104 ( 3) 1085 ( 3) M. tuberculosis, disseminated or extrapulmonary 461 ( 1) 57 ( 2) 518 ( 1) Mycobacterium, other or unidentified species 107 ( 0) 13 ( 0) 120 ( 0) Pneumocystis carinii pneumonia 4898 ( 12) 352 ( 12) 5250 ( 12) Pneumonia, recurrent 128 ( 0) 23 ( 1) 151 ( 0) Progressive multifocal leukoencephalopathy 90 ( 0) 3 ( 0) 93 ( 0) Salmonella septicemia, recurrent 36 ( 0) 3 ( 0) 39 ( 0) Toxoplasmosis of the brain 423 ( 1) 40 ( 1) 463 ( 1) Wasting syndrome 1340 ( 3) 99 ( 3) 1439 ( 3) CD4 < 200ul ( 49) 1974 ( 66) ( 50) 1. The table provides only a minimum estimate of indicator conditions because date of diagnosis may be missing for some indicator conditions. 2. Cases may have more than one condition at time of AIDS diagnosis. 14

17 TABLE 15. ANNUAL CASES OF ADVANCED HIV DISEASE (AIDS) AND RATES PER 100,000 BY SERVICE PLANNING AREA/HEALTH DISTRICT OF RESIDENCE AND YEAR OF DIAGNOSIS REPORTED BY MARCH 31, 2001 Year of Diagnosis Cumulative Service Planning Area/ (1) Total (2) Health District No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Antelope Valley[1] 40 ( 1) ( 1) 9 23 ( 1) 7 19 ( 1) 6 12 ( 1) ( 1) Antelope Valley 40 ( 1) ( 1) 9 23 ( 1) 7 19 ( 1) 6 12 ( 1) ( 1) East[7] 186 ( 7) ( 7) ( 6) ( 7) 8 89 ( 8) ( 6) Bellflower 52 ( 2) ( 1) 6 23 ( 1) 6 23 ( 2) 6 14 ( 1) ( 1) East Los Angeles 39 ( 1) ( 2) ( 1) 7 22 ( 1) 9 22 ( 2) ( 1) San Antonio 55 ( 2) ( 3) ( 3) ( 2) 7 37 ( 3) ( 2) Whittier 40 ( 1) ( 1) 9 12 ( 1) 4 27 ( 2) 8 16 ( 1) ( 1) Metro[4] 949 ( 35) ( 35) ( 35) ( 31) ( 31) ( 39) Central 282 ( 10) ( 13) ( 13) ( 11) ( 11) ( 11) Hollywood-Wilshir 575 ( 21) ( 18) ( 19) ( 15) ( 16) ( 24) Northeast 92 ( 3) ( 3) ( 3) ( 4) ( 5) ( 4) San Fernando[2] 345 ( 13) ( 13) ( 14) ( 13) ( 13) ( 14) East Valley 141 ( 5) ( 5) ( 5) ( 5) ( 4) ( 6) Glendale 45 ( 2) ( 2) ( 2) 9 20 ( 1) 6 13 ( 1) ( 2) San Fernando 26 ( 1) 7 23 ( 1) 6 20 ( 1) 5 21 ( 1) 6 16 ( 1) ( 1) West Valley 133 ( 5) ( 5) ( 6) ( 6) ( 6) ( 5) San Gabriel[3] 176 ( 7) ( 7) ( 7) ( 8) 7 98 ( 8) ( 7) Alhambra 25 ( 1) 7 21 ( 1) 6 18 ( 1) 5 13 ( 1) 4 15 ( 1) ( 1) El Monte 41 ( 2) 9 30 ( 1) 7 40 ( 2) 9 46 ( 3) ( 3) ( 2) Foothill 30 ( 1) ( 1) ( 1) 6 13 ( 1) 4 19 ( 2) ( 1) Pasadena 39 ( 1) ( 1) ( 1) ( 2) ( 1) ( 1) Pomona 41 ( 2) 8 40 ( 2) 8 35 ( 2) 7 24 ( 2) 4 20 ( 2) ( 2) South[6] 252 ( 9) ( 12) ( 11) ( 13) ( 14) ( 9) Compton 51 ( 2) ( 2) ( 2) ( 2) ( 2) ( 2) South 43 ( 2) ( 2) ( 2) ( 2) ( 2) ( 1) Southeast 39 ( 1) ( 2) ( 2) ( 2) ( 3) ( 1) Southwest 119 ( 4) ( 6) ( 5) ( 6) ( 7) ( 5) South Bay[8] 423 ( 16) ( 15) ( 16) ( 17) ( 18) ( 15) Harbor 22 ( 1) ( 1) 8 17 ( 1) 8 15 ( 1) 7 7 ( 1) ( 1) Inglewood 83 ( 3) ( 3) ( 4) ( 3) ( 3) ( 3) Long Beach 266 ( 10) ( 10) ( 9) ( 12) ( 13) ( 9) Torrance 52 ( 2) ( 1) 4 32 ( 2) 7 21 ( 1) 5 21 ( 2) ( 2) West[5] 139 ( 5) ( 4) ( 4) ( 4) ( 3) ( 6) West 139 ( 5) ( 4) ( 4) ( 4) ( 3) ( 6) Total (3) 2704 (100) 2081 (100) 1787 (100) 1516 (100) 1183 (100) (100) 1. Data are provisional due to reporting delay. 2. Includes cases diagnosed prior to Total includes cases with no information on health district/spa. 15

18 TABLE 16. ANNUAL CASES OF ADVANCED HIV DISEASE (AIDS) AND RATES PER 100,000 BY CITY/AREA (1) OF RESIDENCE AND YEAR OF DIAGNOSIS TOP 35 CITIES RANKED BY 1999 RATE, REPORTED BY MARCH 31, 2001 Year of Diagnosis Cumulative (2) Total (3) City/Area No. (Rate) No. (Rate) No. (Rate) No. (Rate) No. (Rate) No. West Hollywood 202 (542.7) 160 (427.2) 78 (206.8) 70 (184.3) 47 (123.0) 2626 Downtown 26 (116.7) 18 ( 79.7) 14 ( 61.1) 20 ( 86.1) 23 ( 97.6) 305 Wholesale 92 (207.9) 82 (182.5) 103 (225.8) 81 (174.9) 31 ( 65.9) 799 Hollywood 394 (168.0) 294 (125.1) 208 ( 88.3) 187 ( 79.2) 137 ( 57.9) 5386 Los Feliz 87 (205.8) 38 ( 89.5) 36 ( 84.4) 31 ( 72.4) 23 ( 53.4) 1101 Adams-La Brea 30 ( 53.0) 25 ( 44.1) 30 ( 52.8) 21 ( 36.9) 25 ( 43.8) 389 Slvlke-Chinatn 121 (139.5) 73 ( 82.6) 63 ( 69.9) 48 ( 52.3) 41 ( 43.8) 1521 Long Beach 316 ( 72.1) 262 ( 59.4) 200 ( 45.0) 158 ( 35.3) 174 ( 38.7) 3845 Miracle Mile S 41 ( 94.8) 35 ( 82.0) 25 ( 59.2) 18 ( 43.2) 15 ( 36.5) 540 Wilshire Ctr N 39 ( 53.2) 25 ( 33.5) 28 ( 36.9) 27 ( 35.0) 25 ( 31.8) 611 N Hollywood 68 ( 59.5) 72 ( 62.8) 47 ( 40.8) 38 ( 32.8) 36 ( 31.0) 1133 Crenshaw 40 ( 59.0) 22 ( 32.7) 33 ( 49.4) 23 ( 34.7) 20 ( 30.4) 502 Westlake 68 ( 50.1) 58 ( 41.7) 42 ( 29.5) 42 ( 28.8) 45 ( 30.1) 817 S Vermont 36 ( 36.7) 39 ( 39.6) 30 ( 30.3) 21 ( 21.1) 26 ( 26.0) 458 Graham 10 ( 39.6) * ( * ) 5 ( 19.0) * ( * ) 7 ( 25.6) 74 Green Meadows 17 ( 31.8) 23 ( 42.6) 13 ( 23.8) 15 ( 27.2) 14 ( 25.1) 241 Miracle Mile N 41 (113.9) 31 ( 87.8) 23 ( 66.4) 17 ( 50.1) 8 ( 24.1) 593 Venice 36 ( 92.3) 15 ( 38.7) 10 ( 26.0) 9 ( 23.5) 9 ( 23.7) 366 Studio City 43 ( 96.6) 29 ( 66.3) 21 ( 48.8) 20 ( 47.4) 9 ( 21.8) 682 Beverly Hills 21 ( 63.3) 9 ( 26.9) 7 ( 20.8) 6 ( 17.7) 7 ( 20.5) 198 El Sereno 14 ( 26.2) 12 ( 21.9) 9 ( 16.0) 6 ( 10.4) 12 ( 20.4) 168 Boyle Heights 28 ( 22.8) 20 ( 15.8) 14 ( 10.7) 20 ( 14.9) 28 ( 20.1) 391 W Adms-Expo Pk 45 ( 33.9) 37 ( 27.6) 40 ( 29.4) 30 ( 21.8) 28 ( 20.1) 670 Eagle Rk-Glasl 34 ( 47.6) 25 ( 34.5) 14 ( 19.1) 11 ( 14.8) 15 ( 19.9) 535 Lawndale 12 ( 41.1) 6 ( 20.3) * ( * ) * ( * ) 6 ( 19.5) 92 Tujunga-Sunland 7 ( 12.3) 7 ( 12.3) * ( * ) 6 ( 10.7) 10 ( 18.0) 140 Lennox * ( * ) 7 ( 22.3) 5 ( 15.6) * ( * ) 6 ( 17.9) 71 Pasadena 49 ( 35.4) 39 ( 28.0) 28 ( 19.9) 20 ( 14.1) 25 ( 17.6) 565 V Nuys-Sher Oaks 64 ( 37.5) 51 ( 29.8) 34 ( 19.8) 34 ( 19.8) 30 ( 17.4) 828 Wilshire Ctr S 47 ( 49.1) 39 ( 39.9) 31 ( 31.1) 19 ( 18.7) 17 ( 16.4) 519 Bell * ( * ) * ( * ) 5 ( 13.7) * ( * ) 6 ( 16.1) 79 Walnut Park 8 ( 47.4) * ( * ) * ( * ) * ( * ) * ( * ) 56 Watts 8 ( 22.7) * ( * ) 5 ( 13.7) * ( * ) 6 ( 15.9) 128 Willowbrook 8 ( 22.2) 12 ( 32.9) 7 ( 18.9) 6 ( 16.0) 6 ( 15.8) 120 Encino-Tarzana 16 ( 25.9) 9 ( 14.8) 11 ( 18.4) 6 ( 10.2) 9 ( 15.6) Includes cities with more than 15,000 residents. The city of Los Angeles is broken down into "areas" or geographic units with more than 15,000 residents. 2. Data are provisional due to reporting delay. 3. Includes cases diagnosed prior to 1995 and after * Fewer than five cases. 16

19 TABLE 17. CUMULATIVE CASES OF ADVANCED HIV DISEASE (AIDS) BY SUPERVISORIAL DISTRICT, GENDER, AGE GROUP, RACE/ETHNICITY, AND EXPOSURE CATEGORY REPORTED BY MARCH 31, 2001 Supervisorial District Total (1) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) GENDER Male 6155 ( 91) 7298 ( 88) ( 97) 5509 ( 93) 3348 ( 91) ( 93) Female 631 ( 9) 1009 ( 12) 535 ( 3) 438 ( 7) 330 ( 9) 3090 ( 7) AGE GROUP <13 59 ( 1) 62 ( 1) 41 ( 0) 28 ( 0) 31 ( 1) 235 ( 1) ( 1) 53 ( 1) 26 ( 0) 23 ( 0) 20 ( 1) 161 ( 0) ( 18) 1596 ( 19) 2383 ( 15) 970 ( 16) 531 ( 14) 7017 ( 16) ( 43) 3572 ( 43) 7463 ( 46) 2786 ( 47) 1536 ( 42) ( 45) ( 25) 2022 ( 24) 4327 ( 27) 1481 ( 25) 985 ( 27) ( 26) ( 9) 718 ( 9) 1492 ( 9) 495 ( 8) 399 ( 11) 3850 ( 9) ( 4) 284 ( 3) 454 ( 3) 164 ( 3) 176 ( 5) 1355 ( 3) RACE/ETHNICITY (2) White 1905 ( 28) 1624 ( 20) ( 69) 3512 ( 59) 2108 ( 57) ( 49) Black 894 ( 13) 4364 ( 53) 1472 ( 9) 849 ( 14) 551 ( 15) 8514 ( 20) Hispanic 3802 ( 56) 2159 ( 26) 3186 ( 20) 1432 ( 24) 891 ( 24) ( 28) Asian 151 ( 2) 132 ( 2) 297 ( 2) 125 ( 2) 105 ( 3) 832 ( 2) AI/AN (3) 25 ( 0) 15 ( 0) 44 ( 0) 23 ( 0) 10 ( 0) 120 ( 0) EXPOSURE CATEGORY Male-male sexual contact 4281 ( 63) 4994 ( 60) ( 82) 4307 ( 72) 2487 ( 68) ( 71) Injection drug user (IDU) 563 ( 8) 816 ( 10) 589 ( 4) 494 ( 8) 296 ( 8) 2956 ( 7) Male-male sexual contact/idu 417 ( 6) 528 ( 6) 1007 ( 6) 419 ( 7) 171 ( 5) 2691 ( 6) Hemophilia/coagulation disorder 26 ( 0) 34 ( 0) 40 ( 0) 39 ( 1) 33 ( 1) 179 ( 0) Heterosexual contact 374 ( 6) 608 ( 7) 349 ( 2) 302 ( 5) 218 ( 6) 1933 ( 5) Transfusion recipient 119 ( 2) 132 ( 2) 139 ( 1) 86 ( 1) 90 ( 2) 583 ( 1) Mother with/at risk for HIV 46 ( 1) 46 ( 1) 24 ( 0) 18 ( 0) 18 ( 0) 162 ( 0) Other/Undetermined 960 ( 14) 1149 ( 14) 700 ( 4) 282 ( 5) 365 ( 10) 3680 ( 9) Total 6786 (100) 8307 (100) (100) 5947 (100) 3678 (100) (100) 1. Include cases with unknown Supervisorial District. 2. Does not include cases whose race/ethnicity is unknown. 3. AI/AN: American Indian, Alaskan Native. 17

20 TABLE 18. ANNUAL CASES OF ADVANCED HIV DISEASE (AIDS) AND RATES PER 100,000 BY SUPERVISORIAL DISTRICT AND YEAR OF DIAGNOSIS REPORTED BY MARCH 31, 2001 Supervisorial District No. [Rate] No. [Rate] No. [Rate] No. [Rate] No. [Rate] DIAGNOSIS YEAR [ 34] 837 [ 46] 1599 [ 90] 612 [ 34] 386 [ 21] [ 36] 802 [ 44] 1449 [ 81] 552 [ 31] 359 [ 19] [ 32] 760 [ 41] 1368 [ 76] 483 [ 27] 318 [ 17] [ 30] 650 [ 35] 1184 [ 66] 523 [ 28] 319 [ 17] [ 22] 550 [ 29] 893 [ 50] 412 [ 22] 216 [ 11] [ 20] 462 [ 24] 606 [ 34] 295 [ 16] 168 [ 9] [ 16] 402 [ 21] 553 [ 31] 254 [ 13] 139 [ 7] [ 14] 347 [ 18] 408 [ 23] 258 [ 13] 122 [ 6] 2000 (1,2) 235 [ 11] 301 [ 16] 302 [ 17] 206 [ 11] 85 [ 4] 1. Rates for year 2000 are calculated using 1999 population estimates. 2. Data are provisional due to reporting delay. 18

21 TABLE 19. PERSONS LIVING WITH ADVANCED HIV DISEASE (AIDS)(1) AND RATE PER 100,000 AT THE END OF CALENDAR YEAR, BY GENDER, AGE, RACE/ETHNICITY AND EXPOSURE CATEGORY REPORTED BY MARCH 31, 2001, Calendar Year (2) No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Rate (3) GENDER Male 8788 (93) (92) (91) (91) (90) (90) (90) (90) 293 Female 633 ( 7) ( 8) ( 9) ( 9) (10) (10) (10) (10) 32 AGE GROUP (4) <13 59 ( 1) 3 63 ( 1) 3 64 ( 1) 3 60 ( 1) 3 59 ( 0) 3 54 ( 0) 3 51 ( 0) 3 49 ( 0) ( 0) 3 37 ( 0) 4 45 ( 0) 5 42 ( 0) 4 45 ( 0) 5 47 ( 0) 5 46 ( 0) 5 49 ( 0) (13) (12) (11) (10) ( 8) ( 7) ( 6) ( 5) (47) (46) (46) (45) (43) (42) (40) (37) (28) (30) (31) (32) (33) (35) (37) (39) ( 8) ( 9) ( 9) (10) (11) (12) (13) (15) ( 3) ( 2) ( 3) ( 3) ( 3) ( 3) ( 4) ( 4) 48 RACE/ETHNICITY (5) White 4666 (50) (47) (45) (45) (43) (41) (40) (39) 194 Black 1840 (20) (21) (21) (21) (21) (21) (22) (22) 403 Hispanic 2656 (28) (30) (31) (32) (33) (34) (35) (36) 129 Asian 188 ( 2) ( 2) ( 2) ( 2) ( 2) ( 2) ( 2) ( 2) 29 AI/AN 24 ( 0) ( 0) ( 0) ( 0) ( 0) ( 0) ( 0) ( 0) 93 EXPOSURE CATEGORY (6) MSM 7013 (74) 7501 (73) 7880 (71) 8418 (70) 9038 (69) 9591 (68) (67) (66) IDU 703 ( 7) 803 ( 8) 874 ( 8) 955 ( 8) 1056 ( 8) 1119 ( 8) 1160 ( 8) 1204 ( 8) MSM/IDU 665 ( 7) 715 ( 7) 723 ( 7) 748 ( 6) 774 ( 6) 819 ( 6) 845 ( 6) 851 ( 5) Hemophi/Transfusion 159 ( 2) 180 ( 2) 182 ( 2) 178 ( 1) 184 ( 1) 181 ( 1) 179 ( 1) 183 ( 1) Heterosexual contact 416 ( 4) 501 ( 5) 631 ( 6) 719 ( 6) 845 ( 6) 933 ( 7) 1012 ( 7) 1068 ( 7) Mother w/at HIV risk 47 ( 0) 52 ( 1) 56 ( 1) 56 ( 0) 58 ( 0) 59 ( 0) 58 ( 0) 59 ( 0) Other/Undetermined 418 ( 4) 538 ( 5) 699 ( 6) 883 ( 7) 1180 ( 9) 1470 (10) 1757 (12) 2043 (13) Total 9421 (100) (100) (100) (100) (100) (100) (100) (100) Includes persons with AIDS whose vital status is unknown. 2. Data are provisional due to reporting delay. 3. Rates for year 2000 are based on 1999 population estimates. 4. Age as of the end of year. 5. Does not include cases whose race/ethnicity is unknown. 6. Rate by exposure category is not available. 19

22 TABLE 20. PERSONS LIVING WITH ADVANCED HIV DISEASE (AIDS) (1,2,3) AND RATE PER 100,000 AS OF DECEMBER 31, 2000 BY SERVICE PLANNING AREA, GENDER, AGE, RACE/ETHNICITY AND EXPOSURE CATEGORY, Service Planning Antelope Valley San Fernando San Gabriel Metro West South East South Bay/LB Total (1) Area No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Rate No. (%) Rate GENDER Male 147 (84) (91) (84) (94) (93) (80) (87) (89) (90) 293 Female 27 (16) ( 9) (16) ( 6) ( 7) (20) (13) (11) (10) 32 AGE GROUP (4) <13 0 (.). * ( 0) 1 6 ( 1) 2 10 ( 0) 4 * ( 0) 3 9 ( 1) 3 9 ( 1) 3 6 ( 0) 2 49 ( 0) * ( *) 4 5 ( 0) 4 8 ( 1) 6 5 ( 0) 5 * ( 0) 4 11 ( 1) 12 * ( 0) 3 13 ( 1) ( 0) ( 5) ( 5) ( 5) ( 4) ( 3) ( 8) ( 7) ( 4) ( 5) (39) (35) (39) (36) (35) (36) (38) (39) (37) (37) (39) (37) (40) (41) (36) (36) (38) (39) (14) (16) (13) (15) (17) (13) (13) (15) (15) ( 4) ( 6) ( 5) ( 4) ( 4) ( 5) ( 4) ( 3) ( 4) 48 RACE/ETHNICITY (5) White 86 (49) (50) (28) (45) (62) ( 5) (19) (44) (39) 194 Black 42 (24) (11) (21) (17) (15) (57) ( 8) (26) (22) 403 Hispanic 46 (26) (35) (46) (35) (20) (37) (71) (27) (36) 129 Asian 0 (.). 59 ( 3) ( 4) ( 2) ( 2) 28 5 ( 0) ( 2) ( 2) ( 2) 29 AI/AN 0 (.). 11 ( 1) 78 * ( 0) ( 0) 349 * ( 0) 65 * ( 0) ( 1) ( 1) ( 0) 93 EXPOSURE CATEGORY (6) MSM 88 (51) 1311 (64) 613 (56) 4404 (74) 630 (74) 732 (48) 574 (59) 1645 (67) (66) IDU 29 (17) 162 ( 8) 114 (10) 290 ( 5) 47 ( 6) 154 (10) 74 ( 8) 239 (10) 1204 ( 8) MSM/IDU 9 ( 5) 101 ( 5) 39 ( 4) 337 ( 6) 43 ( 5) 65 ( 4) 43 ( 4) 152 ( 6) 851 ( 5) Hemophi/Transfusion * ( *) 24 ( 1) 25 ( 2) 30 ( 1) 13 ( 2) 25 ( 2) 22 ( 2) 33 ( 1) 183 ( 1) Heterosexual contact 18 (10) 160 ( 8) 118 (11) 209 ( 4) 35 ( 4) 186 (12) 90 ( 9) 202 ( 8) 1068 ( 7) Mother w/at HIV risk 0 (.) * ( 0) 7 ( 1) 12 ( 0) * ( 0) 12 ( 1) 10 ( 1) 7 ( 0) 59 ( 0) Other/Undetermined 27 (16) 284 (14) 170 (16) 682 (11) 79 ( 9) 349 (23) 154 (16) 162 ( 7) 2043 (13) Total 174 (100) (100) (100) (100) (100) (100) (100) (100) (100) Includes persons with AIDS whose vital status is unknown. 2. Data are current as of March 31, Data are provisional due to reporting delay. 4. Age as of December 31, Does not include cases whose race/ethnicity is unknown. 6. Rate for exposure category is not available. * Fewer than five cases. 20

23 TABLE 21. CASES, DEATHS AND PREVALENCE OF ADVANCED HIV DISEASE (AIDS) BY YEAR REPORTED BY MARCH 31, 2001 Number of Cases Number of Deaths Number of Living (1,2) Year Diagnosed Occurred AIDS Cases (3) 955 (3) (4) Total (5) 1. Includes persons with AIDS whose vital status is unknown. 2. Includes persons living with AIDS at the end of each year. 3. Includes cases prior to Data are provisional due to reporting delay. 5. Includes cases whose date of death is unknown. 21

24 TABLE 22. ADVANCED HIV DISEASE (AIDS) CASES REPORTED IN THE FIRST 3 MONTHS OF BY GENDER, RACE/ETHNICITY, EXPOSURE CATEGORY AND PERCENTAGE CHANGE REPORTED BY MARCH 31, 2001 CASES REPORTED 01/99-03/99 01/00-03/00 01/01-03/01 % change % change % change No. No. No. from 98 to 99 from 99 to 00 from 00 to 01 GENDER Male % -26% -10% Female % -4% -15% RACE/ETHNICITY White % -32% -12% Black % -29% -20% Hispanic % -13% -4% EXPOSURE CATEGORY Male-male sexual contact % -20% -23% Male-male sexual contact/idu % -48% -7% Male IDU % -42% -44% Female IDU % -27% +13% Male heterosexual contact % +20% -83% Female heterosexual contact % 0% -40% Total % -24% -11% DEATHS REPORTED GENDER Male % -16% -14% Female % -30% -21% RACE/ETHNICITY White % -6% -36% Black % -11% +13% Hispanic % -33% 0% EXPOSURE CATEGORY Male-male sexual contact % -15% -31% Male-male sexual contact/idu % +43% -70% Male IDU % -10% +67% Female IDU % -33% -50% Male heterosexual contact % -50% +200% Female heterosexual contact % -50% +20% Total % -18% -15% Persons of other race/ethnicities including Asian, American Indian and Alaskan Native were not included due to small numbers which result in unstable estimates. 22

25 FIGURE 2. MALE ADOLESCENT/ADULT AIDS RATES 1 BY RACE/ETHNICITY 2 AND YEAR OF DIAGNOSIS,, AIDS case definition change Rate per 100, Asian/Pacific Islander Males Year of AIDS Diagnosis 150 Rate Year of AIDS Diagnosis White African-American Latino FIGURE 3. FEMALE ADOLESCENT/ADULT AIDS RATES 1 BY ACE/ETHNICITY 2 AND YEAR OF DIAGNOSIS,, Rate per 100, AIDS case definition change Rate per 10 Asian/Pacific Islander Females Year of AIDS Diagnosis Data are adjusted for reporting delay only. 2 AIDS rates for Native Americans and Alaskan Natives are not presented here because small numbers may result in unstable estimates. Year of AIDS Diagnosis White African-American Latino 23

26 FIGURE 4. PERCENT OF ADULT/ADOLESCENT ADVANCED HIV DISEASE (AIDS) CASES BY RACE/ETHNICITY AND YEAR OF DIAGNOSIS, Percent of Total Cases Year of AIDS Diagnosis White Black Hispanic Other* * Other race/ethnicity includes Asian, American Indian and Alaskan Native. 24

27 Appendix 1: 1993 Revised Classification System for HIV Infection 1 and Expanded Surveillance Case Definition for Adolescents and Adults 2 Clinical categories CD4+ T-cell Categories (A) Asymptomatic, acute (primary) HIV or PGL 3 (B) Symptomatic, not (A) or (C) conditions (C) AIDS-indicator conditions (1) $500/FL A1 B1 C1 (2) /FL A2 B2 C2 (3) <200/FL AIDS-indicator T-cell count A3 B3 C3 1 Criteria for HIV infection for persons ages $13 years: a) repeatedly reactive screening test for HIV antibody (e.g., enzyme immunoassay) with specific antibody identified by the use of supplemental tests (e.g., Western blot, immunofluorescence assay); b) direct identification of virus in host tissues by virus isolation; c) HIV antigen detection; or d) a positive result on any other highly specific licensed test for HIV. 2 The shaded cells illustrate the expanded AIDS surveillance case definition. Persons with an AIDS-indicator condition (Category C) as well as those with CD4+ T-lymphocyte counts <200/FL (Categories A3 or B3) are reportable as AIDS cases in the United States and Territories, effective January 1, PGL=persistent generalized lymphadenopathy. Clinical Conditions Included in the 1993 AIDS Surveillance Case Definition! Candidiasis of bronchi, trachea, or lungs! Candidiasis, esophageal! Cervical cancer, invasive*! Coccidioidomycosis, disseminated or extrapulmonary! Cryptococcosis, extrapulmonary! Cryptosporidiosis, chronic intestinal (>1 month duration)! Cytomegalovirus disease (other than liver, spleen, or nodes)! Cytomegalovirus retinitis (with loss of vision)! Encephalopathy, HIV-related! Herpes simplex: chronic ulcer(s) (>1 month duration) or bronchitis, pneumonitis, or esophagitis! Histoplasmosis, disseminated or extrapulmonary! Isosporiasis, chronic intestinal (>1 month duration)! Kaposi's sarcoma! Lymphoma, Burkitt's (or equivalent term)! Lymphoma, immunoblastic (or equivalent term)! Lymphoma, primary in brain! Mycobacterium avium complex or M. kansasii, disseminated or extrapulmonary! Mycobacterium tuberculosis, any site (pulmonary* or extrapulmonary)! Pneumocystis carinii pneumonia! Pneumonia, recurrent*! Progressive multifocal leukoencephalopathy! Salmonella septicemia, recurrent! Toxoplasmosis of brain! Wasting syndrome due to HIV * Added in the 1993 expansion of the AIDS surveillance case definition. 25

28 Appendix 2: Surveillance Notes Report Delay Report delay is defined as the time interval between the date an AIDS diagnosis was made and the date the case was reported. The median report delay for all cases reported in 1999 was 3 months (range 0 to 158 months). The impact of report delay must be considered when evaluating trends in case numbers and rates over time (Figure 1 and Tables 1, 4-8, 10, 11, 15-16, 18-19, 21). Rates For Table 4, Table 15, Table 16, Table 18, Table 19, and Table 20, AIDS case rates for cases diagnosed in 1990 or after are calculated using population estimates derived from the 1990 census. Exposure Categories Exposure categories are assigned in a hierarchical fashion (listed from highest to lowest in the column headed "Exposure Category"). Cases for which more than one exposure category have been identified are assigned to the category listed highest in the hierarchy. For example, a man who reports sexual contact with another man and heterosexual contact with an HIV-positive women would be classified as "male-male sexual contact." The only exception to this rule includes those men who report both sexual contact with another man and injection-drug use. A separate exposure category has been created for these cases. The "Undetermined" exposure category includes persons with no history of exposure to HIV through one of the defined exposure categories. Cases reported as undetermined include some persons still under investigation. If the investigation identifies a mode of exposure, the case is reclassified into the corresponding exposure category. AIDS-Indicator Conditions At the time of initial case report, all available information about AIDS-defining conditions is collected. However, after a case has been reported, systematic follow-up is not done to identify subsequent AIDS-defining conditions. Therefore, the information presented in Table 14 reflects initial AIDS-defining condition(s) and should be considered a minimum estimate of all AIDS-defining conditions. All persons meeting the CDC AIDS case definition are reportable as required by the California Code of Regulations, Title 17, Section If you have questions on how to report a case, would like a case report form and/or information on the case definition, would like assistance establishing an AIDS surveillance system, or to receive the quarterly surveillance summary and other periodic reports, contact the HIV Epidemiology Program at the address below: HIV Epidemiology Program Los Angeles County Department of Health Services 600 South Commonwealth Avenue, Room 805 Los Angeles, California Phone: (213) FAX: (213)