11 Eye. To be used in conjunction with NICE guidance/guidelines, the British National Formulary for adults and/or children, and

Transcription

1 11 Eye To be used in conjunction with NICE guidance/guidelines, the British National Formulary for adults and/or children, and The Royal College of Ophthalmologists guidelines Index 11.1 Administration of drugs to the eye 11.2 Control of microbial contamination 11.3 Anti-infective eye preparations 11.4 Corticosteroids and other anti-inflammatory preparations 11.5 Mydriatics and cycloplegics 11.6 Treatment of glaucoma 11.7 Local anaesthetics 11.8 Miscellaneous ophthalmic preparations 11.9 Contact lenses

2 11.1 Administration of drugs to the eye BNF notes on the administration of drugs to the eye Return to index

3 11.2 Control of microbial contamination BNF notes on the control of microbial contamination Return to index

4 11.3 Anti-infective eye preparations BNF notes on antifungals DRUG BRAND / FORMULATION NOTES Antibacterials Azithromycin dihydrate Chloramphenicol Ciprofloxacin Fusidic acid Gentamicin Levofloxacin Moxifloxacin Azyter 0.5% eye drops 10 ml 0.5% preservative-free eye drops 10 ml 0.5% eye drops single-use units x20 1% eye ointment 4 g 0.3% eye drops 5 ml 1% eye drops 5 g 0.3% eye drops 10 ml Gentamicin forte 1.5% preservative-free eye drops 10 ml 0.5% eye drops 5 ml 0.5% preservative-free eye drops single-use units x30 Moxivig

5 Neomycin sulfate Ofloxacin Propamidine isetionate Tobramycin Neomycin 0.3% eye drops 5 ml Brolene Tobravisc Antifungals Clotrimazole 1% preservative-free eye drops 10 ml Antivirals Aciclovir Ganciclovir Trifluorothymidine 3% eye ointment 4.5 g 0.15% ophthalmic gel 5 g 1% preservative-free eye drops 10 ml Return to index

6 11.4 Corticosteroids and other anti-inflammatory preparations NICE guidance on dexamethasone intravitreal implant for the treatment of macular oedema secondary to retinal vein occlusion Corticosteroids Betamethasone Betamethasone with neomycin Dexamethasone Dexamethasone with antibacterials Fluorometholone Hydrocortisone acetate Loteprednol etabonate Prednisolone 0.1% eye ointment 3 g Betnesol-N 0.1% eye drops 5 ml / 10ml 0.1% eye drops single-use units x20 (Maxitrol) Dexamethasone 0.1%/neomycin 0.35%/polymixin B sulphate 600 units/ml eye drops 5 ml (Maxitrol) Dexamethasone 0.1%/neomycin 0.35%/polymixin B sulphate 600 units/g eye ointment 3.5 g (Tobradex) Dexamethasone 0.1%/tobramycin 0.3% eye drops 5 ml 0.1% eye drops 5 ml / 10ml Hydrocortisone 0.5% eye drops 5 ml 0.5% eye drops 10 ml 0.5% eye drops single-use units x20

7 1% eye drops 5 ml / 10ml Rimexolone 1% eye drops 5 ml Intravitreal corticosteroids Dexamethasone 700 micrograms intravitreal injection Ozurdex As per NICE only (see link above) Other anti-inflammatory preparations Antazoline sulfate Azelastine hydrochloride Emedastine Epinastine hydrochloride Ketotifen Lodoxamide Nedocromil sodium Olopatadine Sodium cromoglicate (Otrivine-Antistin) Xylometazoline 0.05%/antazoline 0.5% eye drops 10 ml Optilast Emadine Relestat Zaditen 0.1% eye drops 10 ml 2% eye drops 5 ml Rapitil 1 mg/ml eye drops 5 ml Opatanol 2% eye drops 13.5 ml Catacrom

8 Return to index

9 11.5 Mydriatics and cycloplegics Antimuscarinics Atropine sulfate Cyclopentolate hydrochloride Homatropine hydrobromide Tropicamide Tropicamide with phenylephrine 1% eye drops 10 ml 1% preservative-free eye drops 10 ml 1% eye drops single-use units x20 0.5% eye drops 5 ml 0.5% eye drops single-use units x20 1% eye drops 5 ml 1% eye drops single-use units x20 Homatropine Mydriacyl 0.5% & 1% eye drops single-use units x20 See sympathomimetics, below Sympathomimetics Phenylephrine hydrochloride Phenylephrine hydrochloride with tropicamide 2.5% & 10% eye drops single-use units x20 Mydriasert Return to index

10 11.6 Treatment of glaucoma NICE quality standard for glaucoma NICE guideline on the diagnosis and management of chronic open angle glaucoma and ocular hypertension Beta-blockers Betaxolol Carteolol hydrochloride Levobunolol hydrochloride Timolol Timolol with bimatoprost Timolol with brimonidine Timolol with brinzolomide Timolol with dorzolamide Timolol with latanoprost 0.25% suspension eye drops 5 ml 0.5% eye drops 5 ml Carteolol 1% & 2% eye drops 5 ml 0.5% eye drops 5 ml 0.5% preservative-free eye drops single-use units x % & 0.5% eye drops 5 ml 0.5% preservative-free eye drops single-use units x % long acting eye drops 2.5 ml See prostaglandin analogues and prostamides, below See sympathomimetics, below See carbonic anhydrase inhibitors and systemic drugs, below See carbonic anhydrase inhibitors and systemic drugs, below See prostaglandin analogues and prostamides, below

11 Timolol with travoprost See prostaglandin analogues and prostamides, below Prostaglandin analogues and prostamides Bimatoprost Bimatoprost with timolol Latanoprost Latanoprost with timolol Tafluprost Travoprost Travoprost with timolol 0.01% & 0.03% eye drops 3 ml (Ganfort) Bimatoprost 0.3 mg/timolol 5 mg/ml eye drops 3 ml 50 micrograms/ml eye drops 2.5 ml Xalatan Latanoprost with Timolol (Xalacom) Latanoprost 0.005%/timolol 0.5% eye drops 2.5 ml 15 micrograms/ml eye drops single-use units x30 40 micrograms/ml eye drops 2.5 ml (DuoTrav) Travoprost 40 micrograms/timolol 5 mg/ml eye drops 2.5 ml Sympathomimetics Brimonidine tartrate Brimonidine tartrate with timolol 0.2% eye drops 5 ml (Combigan) Brimonidine 0.2%/timolol 0.5% eye drops 5 ml Carbonic anhydrase inhibitors and systemic drugs Acetazolamide 250 mg tablets x mg injection vial

12 250 mg sustained release capsules x 30 Brinzolamide Brinzolamide with timolol Dorzolamide Dorzolamide with timolol 10 mg/ml eye drops 5 ml (Azarga) Brinzolamide 10 mg/timolol 5 mg/ml eye drops 5 ml 2% eye drops 5 ml 2% preservative-free eye drops single-use units x60 Dorzolamide with Timolol (Cosopt) Dorzolamide 2%/timolol 0.5% eye drops 5 ml (Cosopt) Dorzolamide 2%/timolol 0.5% preservativefree eye drops single-use units x60 Miotics Pilocarpine 1%, 2% & 4% eye drops 10 ml 2% preservative-free eye drops 10 ml 2% eye drops single-use units x20 Return to index

13 11.7 Local anaesthetics Local anaesthetics Cocaine Lidocaine hydrochloride with fluorescein Oxybuprocaine hydrochloride Proxymetacaine hydrochloride Proxymetacaine hydrochloride with fluorescein Tetracaine hydrochloride 4% preservative-free eye drops 2 ml Lidocaine 4%/fluorescein 0.25% eye drops single-use units x20 0.4% eye drops single-use units x20 0.5% eye drops single-use units x20 Proxymetacaine 0.5%/fluorescein 0.25% eye drops single-use units x20 0.5% & 1% eye drops single-use units x20 Return to index

14 11.8 Miscellaneous ophthalmic preparations NICE guidance on ranibizumab and pegaptanib for the treatment of age-related macular degeneration NICE recommends ranibizumab for the treatment of diabetic macular oedema Tear deficiency, ocular lubricants, and astringents Acetylcysteine Carbomers Carmellose sodium Hydroxyethylcellulose Hydroxypropyl guar (Ilube) Acetylcysteine 5%/hypromellose 0.35% eye drops 10 ml Clinitas Gel GelTears Liposic Liquivisc Lumecare Long Lasting Tear Gel (Viscotears) Carbomer % eye drops 10 g (Viscotears) Carbomer % preservative-free eye drops single-use units x30 (Optive) Carmellose 0.5% in glycerol eye drops 10 ml Carmellose 0.5% & 1% eye drops single-use units x30 (Artificial Tears) 0.44% eye drops single-use units x20 (Systane) Hydroxypropyl guar 0.2% eye drops 10 ml Systane Ultra (Systane) Hydroxypropyl guar 0.2% preservative-free eye drops single-use units x28

15 Hypromellose Liquid paraffin Paraffin, yellow, soft Polyvinyl alcohol Sodium chloride Hypromellose 0.3% eye drops 10 ml Artelac Isopto Alkaline Isopto Plain Tear-Lac (Tears Naturale) Dextran %/hypromellose 0.3% eye drops 15 ml Hypromellose 0.3% preservative-free eye drops single-use units x30 Artelac SDU single use Hydromoor single use Lumecare Preservative Free Tear Drops single use Tears Naturale Single Dose Lacri-Lube eye ointment 3.5 g VitA-POS Simple Eye Ointment 4g Polyvinyl alcohol 1.4% eye drops 15 ml Liquifilm Tears Sno Tears Sodium chloride 0.9% eye drops single-use units x20 Sodium chloride 0.9% eye lotion 500 ml Sodium chloride 5% eye drops 10 ml Sodium chloride 5% eye ointment 5 g Sodium chloride 5% preservative-free eye drops 10 ml Balanced Salt Solution singles 19 ml

16 Sodium hyaluronate Balanced Salt Solution 500 ml bag x6 Balanced Salt Solution Plus 500 ml bottle Sodium hyaluronate 0.1% preservative-free eye drops 10 ml Sodium hyaluronate 0.2% preservative-free eye drops 10 ml Hyabak Hylo-Care Hylo-Forte Hylo-Tear Oxyal Vismed Multi Clinitas single use Lubristil single use Ocusan single use Vismed single use Vismed Gel single use Ocular diagnostic and peri-operative preparations and photodynamic treatment ocular diagnostic preparations Fluorescein sodium Fluorescein sodium with local anaesthetic Fluorescein 1% & 2% eye drops single-use units x20 Fluorescein 1 mg ophthalmic strips x100 Fluorescein 20% 5 ml injection ampoules x 5 / 10 See section 11.7 Local anaesthetics, above Ocular diagnostic and peri-operative preparations and photodynamic treatment ocular peri-operative drugs

17 Acetylcholine chloride Apraclonidine Bromfenac Diclofenac sodium Flurbiprofen sodium Ketorolac trometamol Nepafenac 20 mg intra-ocular injection 2 ml vial with diluent 0.5% eye drops 5 ml 1% eye drops single-use units 12 x 2 Yellox 0.1% eye drops single-use units x40 Ocufen 0.5% eye drops 5 ml Nevanac Ocular diagnostic and peri-operative preparations and photodynamic treatment subfoveal choroidal neovascularisation Pegaptanib sodium Macugen As per NICE only (see links above) Ranibizumab Ranibizumab 2.3 mg/0.23 ml intravitreal injection vial Lucentis As per NICE only (see links above) Verteporfin Verteporfin 15 mg injection vial Visudyne Miscellaneous Alteplase Ciclosporin Ciclosporin A 100 micrograms/0.1 ml intravitreal injection 2 ml vial 500 micrograms/2 ml intravitreal injection kit 0.06% preservative-free eye drops 10 ml 0.2% eye ointment 3.5 g

18 Disodium edetate Glycerol Hydroxypropyl methylcellulose IML blue solution Lissamine green Membrane Blue Mydricaine Oxane oil Perfluoradecalin heavy liquid Perfluoroctane liquid Polihexanide Potassium ascorbate Povidone iodine Silicone oil Sodium hyaluronate Trypan 0.37% eye drops 10 ml 0.37% sterile solution 20 ml 2% intra-ocular injection 2.5 ml syringe (Visicrom) 0.5 ml vials x 5 (Brilliant Peel) ophthalmic strips x100 sterile injection 0.5 ml dual syringe x5 No ml injection ampoules x ml vial 5 ml vial 5 ml vial 0.02% preservative-free eye drops 10 ml 10% preservative-free eye drops 10 ml 5% preservative-free eye drops 10 ml 2000 CPS 10 ml 5000 CPS 10 ml (Siluron) 1% & 1.2% intra-ocular injection 1 ml syringe 0.5 ml sterile solution vial x10 (Vision Blue) Return to index

19 11.9 Contact lenses BNF notes on contact lenses Miscellaneous contact lens preparations Eye drops Contact lense solutions Blink Contacts eye drops multi-dose bottle 10 ml Blink Contacts eye drops single-use units x20 Physiological saline preservative-free solution 30 ml vials x12 Amo Lens Plus Ocupure saline solution 360 ml Boston Advance/Bausch & Lomb cleaner solution 30 ml Boston Advance/Bausch & Lomb cleaner solution 120 ml I-Clean Contact Lens Cleaner solution 50 ml Synergi Multipurpose Contact Lens solution 250 ml x3 (3 month pack) Return to index