UNIVERSITY OF MALTA FACULTY OF MEDICINE & SURGERY PHARMACY DEPARTMENT MATERIAL SAFETY DATA SHEET POTASSIUM DIHYDROGEN PHOSPHATE

Transcription

1 Table of Contents Page 1. Chemical Product 2 2. Composition and Information on Ingredients 2 3. Hazards Identification 2 4. First Aid Measures 3 5. Fire and Explosion Data 4 6. Accidental Release Measures 5 7. Handling and Storage 5 8. Exposure Controls/ Personal Protection 6 9. Physical and Chemical Properties Stability and Reactivity Data Toxicological Information Ecological Information Disposal Considerations References Appendices Revision History 9 Page 1 of 9

2 1. Chemical Product Product Name: Potassium dihydrogen phosphate Chemical name: Potassium dihydrogen phosphate Synonyms: Monopotassium phosphate, potassium dihydrogen phosphate, phosphoric acid, monopotassium salt Chemical Formula: KH 2 O 4 2. Composition and Information on Ingredients Composition: Potassium phosphate monobasic 100% by weight Toxicological Data on Ingredients: N/A 3. Hazards Identification Potential Acute Health Effects: Hazardous in case of skin contact (irritant), eye contact (irritant), ingestion and inhalation, and slightly hazardous in case of skin contact (permeator). Potential Chronic Health Effects: CARCINOGENIC EFFECTS: N/A MUTAGENIC EFFECTS: N/A TERATOGENIC EFFECTS: N/A DEVELOPMENTAL TOXICITY: N/A. Repeated or prolonged exposure is not known to aggravate medical condition. Page 2 of 9

3 4. First Aid Measures General measures: N/A Skin contact: In case of contact, immediately flush skin with plenty of water and cover the irritated skin with an emollient. Remove any contaminated clothing and shoes, and wash clothing with cold water, and thoroughly clean shoes before reuse. Seek medical attention. Serious skin contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention. Eye contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention. Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel, and never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband. Serious indigestion: N/A Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention. Serious inhalation: N/A Page 3 of 9

4 5. Fire and Explosion Data Flammability of the Product: Non flammable. Auto-Ignition Temperature: Not applicable. Flash points: Not applicable. Flammable limits: Not applicable. Products of Combustion: N/A Fire Hazards in Presence of Various Substances: Not applicable. Explosion Hazards in Presence of Various Substances: - Risks of explosion of the product in presence of mechanical impact: N/A - Risks of explosion of the product in presence of static discharge: N/A Fire fighting media and Instructions: Not applicable. Special Remarks on Fire Hazards: N/A Special Remarks on Explosion Hazards: N/A Page 4 of 9

5 6. Accidental Release Measures NB: Wear appropriate protective equipment/clothing including gloves before removing any spills. Small spill: Use appropriate tools to place the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of the material according to local and regional authority requirements. Large spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow the mixture to evacuate through the sanitary system. 7. Handling and Storage Precautions: Do not ingest or breathe in dust, and wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes and keep away from incompatibles such as alkalis. Storage: Keep container tightly closed and store in a cool, well-ventilated area. Page 5 of 9

6 8. Exposure Controls/Personal Protection Airborne Exposure Limits: N/A Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal Protection: Splash goggles, lab coat, dust respirator, making sure to use an approved/certified respirator or equivalent, and gloves. 9. Physical and Chemical Properties Physical state and appearance: White solid (Crystalline solid. Granular powder solid). Odour: Odourless Taste: N/A Molecular Weight: g/mole ph (1% solution/water): 4.5 [Acidic.] in a 5% soln/water Boiling Point: N/A Melting Point: 253 C (487.4 F) Critical Temperature: N/A Specific Gravity (Water = 1): 2.34 Vapour Pressure (mmhg): Not applicable. Vapour Density: N/A Volatility: N/A Odour Threshold: N/A Water/Oil Distribution Coefficient: N/A Ionicity (in Water): N/A Dispersion Properties: See solubility in water. Solubility: Soluble in cold water and insoluble in alcohol. Page 6 of 9

7 10. Stability and Reactivity Data Stability: The product is stable. Corrosivity: Non-corrosive in presence of glass. Instability temperature: N/A Conditions of Instability: Incompatible materials. Incompatibles: Non-corrosive in presence of glass. Polymerization: Will not occur. 11. Toxicological Information Toxicity to animals: Acute dermal toxicity (LD50): >4640 mg/kg [Rabbit]. Effects on humans: Acute potential health effects: - Skin: May cause skin irritation. Risk of skin absorption is slight. - Eye: Dust may cause eye irritation. - Inhalation: Inhalation may cause respiratory tract irritation, coughing and choking. - Ingestion: Ingestion of large amounts may cause nausea, vomiting, abdominal discomfort (cramps) and diarrhoea. Also, symptoms of potassium poisoning may occur, which may include slow heartbeat, peripheral vascular collapse with fall in blood pressure, cardiac arrhythmias, heart block, accelerated breathing, and muscle weakness, heaviness of the legs, flaccid paralysis, cold skin and gray pallor. May affect behaviour (listlessness, mental confusion). Chronic potential health effects: Dermatitis may develop from repeated or prolonged skin contact. MUTAGENIC EFFECTS: N/A TERATOGENIC EFFECTS: N/A DEVELOPMENTAL TOXICITY: N/A Other information: Hazardous in case of skin contact (irritant), ingestion and inhalation, and slightly hazardous in case of skin contact (permeator). Page 7 of 9

8 12. Ecological Information Ecotoxicity: N/A 13. Disposal Considerations Waste Disposal: Waste must be disposed of in accordance with local environmental control regulations. 14. References - Sciencelab.com. Material Safety Data Sheet; Potassium dihydrogen phosphate [Online] [cited 2012 Oct 10]. Available from: URL: - Bakerbro.com. Material Safety Data Sheet; Potassium dihydrogen phosphate [Online] [cited 2012 Oct 10]. Available from: URL: hydrous_msds.pdf - Cen.iitb.ac.in. Material Safety Data Sheet; Potassium dihydrogen phosphate [Online] [cited 2012 Oct 10]. Available from: URL: - Westliberty.edu. Material Safety Data Sheet; Potassium dihydrogen phosphate [Online] [cited 2012 Oct 10]. Available from: URL: Page 8 of 9

9 15. Appendices N/A 16. Revision History Version Number Amendments/ Reasons for change 01 Initial Release Page 9 of 9