Get your runny, stuffy nose to cool it. Available in-office. Drip. Sniff. Drip. Minimal downtime. Enjoy life without tissues

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1 Get your runny, stuffy nose to cool it. Drip. Sniff. Drip. Enjoy life without tissues Available in-office Minimal downtime

2 Get Your Life Back With a cool treatment, using ClariFix cryotherapy. Enjoy Life Without Tissues After ClariFix cryotherapy, patients report a reduction in runny & stuffy nose symptoms Available In-Office Treatment can typically be done in your doctor s office with local anesthesia Minimal Downtime Most patients typically return to normal activity the same day I couldn t focus on my work. My nose was constantly dripping. It was a horrible thing. The Doctor gave me every pill, nose spray, and shot, and nothing touched it. After cryotherapy with the ClariFix device, all my symptoms started to subside and within 3 weeks to a month, my symptoms were gone. I stopped sneezing, my nose stopped dripping, and I ve had nothing but quality of life since. Actual ClariFix Patient and 3 year chronic rhinitis sufferer

3 Are you one of the 24+ MILLION Americans who suffers with Chronic Rhinitis? 1 Chronic rhinitis is frequent inflammation of the nose with symptoms such as: Runny nose Nasal congestion Post nasal drip (mucus in the throat) Nasal sprays not working? What Causes Chronic Rhinitis? Out of balance nerves may be sending too many signals to your nose, telling it to drip, run and swell more than necessary. If treatments, such as nasal sprays, drops and pills are not working for you, or you are looking for a solution that lasts longer without the side effects of medications, it s time to try ClariFix.

4 How Does ClariFix Work? Using cold treatment called cryotherapy, the ClariFix device reduces your runny, stuffy nose by interrupting the signals these out of balance nerves send. Goes to the root of the problem: the inflamed nasal lining and underlying nerves Delivers cold temperatures to the out of balance nerves in the back of the nose Stops the source of the symptoms for lasting relief The Cool Effects of ClariFix Cryotherapy Decrease in runny nose and congestion Patients reported a significant decrease in runny nose and congestion compared to initial symptoms. 2,3 Lasting improvement 4 out of 5 patients reported longlasting symptom improvement. 2,3

5 Frequently Asked Questions How long until I see an improvement? Most patients begin to see improvement between 2 and 6 weeks post-treatment. What does the treatment feel like? You may experience slight pressure, a cooling sensation in the nose and/or around the molars, or some discomfort during and/or after the treatment. What are the side effects? The most common side effects associated with ClariFix cryotherapy are temporary increased congestion and transient pain or discomfort.* How long does it take? You can typically expect to spend about an hour in the doctor s office.

6 Is ClariFix Right For You? If your answer is YES to any of these questions, talk to your ENT doctor. SYMPTOMS Do you experience these symptoms frequently or on a regular basis? Watery Runny Nose Yes No Nasal Congestion Yes No Congestion in the Morning Yes No Post-Nasal Drip Yes No Clearing of the Throat Yes No Available by Rx only. Only your doctor can determine if ClariFix is right for you. The ClariFix device is intended to be used as a cryosurgical tool for the destruction of unwanted tissue during surgical procedures, including in adults with Chronic Rhinitis. *Adverse events were those usually associated with post-cryosurgery in nasal passageways and included: pain/discomfort, headache, facial pain, bleeding, dry nose, ear blockage. By day 90, symptoms had either resolved or rated as mild. ARRINEX, INC E Bayshore Rd, Ste 26A Redwood City, CA CDC: Accessed Nov 15, K162608, Data on File: A Clinical Report, Arrinex 3 Hwang P, et al. Cryosurgical Posterior Nasal Tissue Ablation for the Treatment of Rhinitis. Int Forum Allergy Rhinol Oct;7(10): Arrinex, Inc. All rights reserved. ClariFix is a registered trademark of Arrinex, Inc. MRK-0552 Rev D

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