Annotation SNPEff_ Annotation SNPEff_. SNPEff_. Annotation. SNPEff_. Annotation. SNPEff_. Annotation. SNPEff_. Annotation

Transcription

1 Chr Gene p-value Binned_ variants Phenotype Biological_Feature Note 11 DRD Asthma Gene 16 CES Asthma Gene 19 LDLR Asthma Gene 10 ARID5B Asthma Gene 10 CYP2C Asthma Gene 7 CYP3A Asthma Gene 5 DRD BPH Gene 11 BDNF BPH Gene 13 HTR2A Cataracts Gene 5 NR3C Cataracts Gene 10 CYP2C Cataracts Gene 1 DPYD Cataracts Gene 9 ABCA Cataracts Gene 1 CACNA1S Diverticulosis Gene 1 PEAR Diverticulosis Gene 5 HTR1A GERD Gene 10 ARID5B GERD Gene 16 HSD11B Hypertension Gene 7 GLCCI Hypertension Gene 17 CRHR Hypothyroidism Gene 1 DPYD Hypothyroidism Gene 16 VKORC Hypothyroidism Gene 14 TCL1A Hypothyroidism Gene 10 CYP2C Hypothyroidism Gene 6 ESR Hypothyroidism Gene 11 BDNF Type II Diabetes Gene 19 CYP2A Type II Diabetes Gene 11 SLCO2B Type II Diabetes Gene 15 CYP1A Type II Diabetes Gene 10 CYP2C Uterine Fibroids Gene 10 CYP2C Uterine Fibroids Gene 2 UGT1A Uterine Fibroids Gene 20 PTGIS Uterine Fibroids Gene 6 SLC22A Uterine Fibroids Gene 10 ABCC Uterine Fibroids Gene 13 HTR2A Uterine Fibroids Gene 5 HTR1A Uterine Fibroids Gene 12 SLCO1B Uterine Fibroids Gene 3 SCN5A Uterine Fibroids Gene 10 ARID5B ASTHMA 19 LDLR ASTHMA 4 NR3C ASTHMA 10 GRK ASTHMA 7 CYP3A ASTHMA 9 ABCA ASTHMA 2 ABCB ASTHMA PRIME_ DOWNSTREAM _

2 12 SLCO1A ASTHMA 16 CES ASTHMA 19 CYP2A ASTHMA 11 SLCO2B ASTHMA 7 POR ASTHMA 7 AHR ASTHMA 5 SLC6A ASTHMA 10 ALOX ASTHMA 11 DRD ASTHMA 22 CYP2D BPH 16 CES BPH 6 SLC22A BPH 4 GRK BPH 13 HTR2A Cataracts 10 CACNB Cataracts 20 PTGIS Cataracts 7 KCNH Cataracts 5 NR3C Cataracts 9 PTGS Cataracts 4 NR3C Cataracts 9 NTRK Cataracts 15 CYP1A Diverticulosis 14 TCL1A Diverticulosis 16 CES Diverticulosis 4 NR3C Diverticulosis 19 LDLR Diverticulosis 7 CYP3A Diverticulosis PRIME_ PRIME_ PRIME_ PRIME_

3 1 PEAR Diverticulosis 5 SLC6A Diverticulosis 7 AHR Diverticulosis 10 CYP2C Diverticulosis 7 TBXAS Diverticulosis 10 GRK Diverticulosis 1 CACNA1S Diverticulosis 16 CES Diverticulosis 12 CACNA1C GERD 10 ARID5B GERD 19 CYP2B GERD 7 GLCCI Hypertension 6 SLC22A Hypothyroidism 17 CRHR Hypothyroidism 1 DPYD Hypothyroidism 10 CYP2C Hypothyroidism 12 VDR Hypothyroidism 17 SLC47A Hypothyroidism 14 TCL1A Hypothyroidism 1 NPR Hypothyroidism 5 SLC6A Hypothyroidism 7 AHR Hypothyroidism 17 SLC47A Hypothyroidism 17 CRHR Hypothyroidism 6 ESR Hypothyroidism 7 TBXAS Hypothyroidism 9 ABCA Hypothyroidism PRIME_ PRIME_ PRIME_ PRIME_ PRIME_ PRIME_

4 22 COMT Hypothyroidism 16 CES Hypothyroidism 6 ESR Hypothyroidism 15 CYP1A Hypothyroidism 11 BDNF Type II Diabetes 16 ZNF Type II Diabetes 11 SLCO2B Type II Diabetes 11 SLCO2B Type II Diabetes 11 BDNF Type II Diabetes 12 CACNA1C Type II Diabetes 9 NTRK Type II Diabetes 17 SLC47A Type II Diabetes 15 CYP1A Type II Diabetes 6 SLC22A Type II Diabetes 5 NR3C Type II Diabetes 10 ALOX Type II Diabetes 19 CYP2A Type II Diabetes 20 PTGIS Type II Diabetes 6 SLC22A Type II Diabetes 10 CACNB Type II Diabetes 15 CYP1A Type II Diabetes 10 CYP2C Uterine Fibroids 2 UGT1A Uterine Fibroids 17 SLC47A Uterine Fibroids 9 DBH Uterine Fibroids 11 SLCO2B Uterine Fibroids 16 CES Uterine Fibroids PRIME_ PRIME_ SPLICE_SITE_ REGION_LOW PRIME_ PRIME_

5 3 SCN5A Uterine Fibroids 11 BDNF Uterine Fibroids 10 CYP2C Uterine Fibroids 7 TBXAS Uterine Fibroids 19 LDLR Uterine Fibroids 13 HTR2A Uterine Fibroids 5 NR3C Uterine Fibroids 12 CACNA1C Uterine Fibroids 11 DRD Uterine Fibroids X MAOA Uterine Fibroids 17 SLC47A Uterine Fibroids 6 SLC22A Uterine Fibroids PRIME_ PRIME_