Asthma Prevention and Management Guidelines
|
|
- Annabel Pierce
- 6 years ago
- Views:
Transcription
1 DOI: / Asthma Prevention and Management Guidelines 2003, Japan (JGL 2003): English summary Report of the Research Group for Asthma Prevention and Management Guidelines, supported by the Immunology & Allergy Research Study Project Ministry of Health, Labour and Welfare, Japan Guest Editors Sohei Makino Ken Ohta Sankei Nishima Akihiro Morikawa 12 figures and 20 tables, 2005 Basel Freiburg Paris London New York Bangalore Bangkok Singapore Tokyo Sydney
2 S. Karger Medical and Scientific Publishers Basel Freiburg Paris London New York Bangalore Bangkok Singapore Tokyo Sydney Drug Dosage The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center (see General Information ). Copyright 2005 by S. Karger AG, P.O. Box, CH 4009 Basel (Switzerland) Printed in Switzerland on acid-free paper by Reinhardt Druck, Basel ISBN Fax karger@karger.ch
3 Vol. 136, Suppl. 1, 2005 Contents 1 Foreword Chapter 1 Definition, Diagnosis, Disease Types, and Classification of Asthma 3 Definitions 3 Definition of Adult Asthma 3 Definition of Childhood Asthma 3 Asthma Classification Based on Severity and Frequency of Asthma Attacks Chapter 2 Epidemiology of Asthma 5 Epidemiology of Asthma 5 Survey Methods 5 Survey Results 5 Current Prevalence of Asthma Symptoms 5 Changes over Time in Asthma Symptom Prevalence 6 Regional Differences in Asthma Prevalence 7 Male-Female Ratio 7 Age at Onset 8 Family History of Asthma 8 Number and Percentage of Patients Diagnosed with Asthma 8 Asthma Deaths 10 Asthma Deaths in Adults 12 Asthma Deaths in Children 13 Countermeasures to and Prevention of Asthma Deaths 13 References 13 Further Reading 2005 S. Karger AG, Basel Fax karger@karger.ch Access to full text and tables of contents, including tentative ones for forthcoming issues:
4 Chapter 3 Pharmacologic Control of Asthma 14 Pharmacologic Treatment for Long-Term Management of Asthma 14 Drugs 14 Controller Medications 15 Corticosteroids 17 Sustained-Release Theophylline Agonists 17 Anti-Allergic Agents 19 Reliever Medications 19 Corticosteroids Agonists 20 Subcutaneous Epinephrine Injection 20 Aminophylline/Theophylline 20 Inhaled Anti-Cholinergic Drugs 20 Other Drugs and Therapy 20 Traditional Chinese Herbal Medicines (Kampo) 21 Hyposensitization Therapy 21 Nonspecific Therapy 22 A Stepwise Plan of Pharmacologic Therapy in Adults 22 Goal of Asthma Control 22 Implementation of Asthma Therapy 22 Four Steps in Long-Term Management of Asthma 22 Step 1: Mild Intermittent Asthma 22 Step 2: Mild Persistent Asthma 23 Step 3: Moderate Persistent Asthma 23 Step 4: Severe Persistent Asthma 25 Supplement: Intractable Asthma 25 Follow-Up Evaluation and Testing 25 Management of Acute Exacerbation (Attacks) in Adults 25 Management of Patients at Home 26 Standard Drugs Used for the Treatment of Asthma Attacks (Reliever Medications) 26 Inhaled 2 -Agonists 26 Subcutaneous Epinephrine 26 Theophylline 27 Factors Which Affect Serum Theophylline Level 27 Corticosteroids 29 Oxygen 29 Other Therapy 29 Procedures for Emergency Outpatient Treatment IV Int Arch Allergy Immunol Vol. 136, Suppl. 1, 2005 Contents
5 29 Management and Treatment of Childhood Asthma 29 Management of Acute Attacks in Childhood Asthma 29 Home Management of Patients 31 Treatment in a Medical Facility 31 Treatment of Mild Attacks 31 Treatment of Moderate Attacks 34 Treatment of Severe Attacks 35 Treatment for Acute Respiratory Failure 36 Indications for Hospitalization 36 Medication Plans for Long-Term Management of Childhood Asthma 37 Controller Medications 37 Anti-Allergic Drugs 37 Inhaled Corticosteroids 40 Sustained-Release Theophylline Agonists 41 Stages in Long-Term Asthma Management (Treatment Steps) 41 Important Considerations when Treatment Is Stepped up or Stepped down 41 Assessing Treatment Step-Down 41 Sustaining Asthma Control 42 Assessing Treatment Step-Up 42 Discontinuing Long-Term Asthma Medication 42 Steps in Asthma Treatment 42 Mild Intermittent Asthma (Step 1) 42 Mild Persistent Asthma (Step 2) 43 Moderate Persistent Asthma (Step 3) 43 Severe Persistent Asthma (Step 4) 43 Early Intervention 44 Primary Prevention 44 Secondary Prevention 45 References 49 Further Reading Contents Int Arch Allergy Immunol Vol. 136, Suppl. 1, 2005 V
6 The following groups participated in the preparation of the Asthma Prevention and Management Guidelines 2003, Japan (Update from: JGL1998). 1995/1996 Research Group of Bronchial Asthma (Research group director S. Makino and 40 members), Allergy Division, Long-Term Chronic Disease Research Projects, supported by Ministry of Health, Labour and Welfare, Japan Research Group for Asthma Prevention and Management Guidelines (Research group director S. Makino and 44 members), Division of Effective Approaches for Treatment of Immunological and Allergic Disorders, Immunology and Allergy Research Study Project, supported by Ministry of Health, Labour and Welfare, Japan S. Karger AG, Basel Fax Accessible online at:
7 Members of the research groups are as follows: Director: Dr. Sohei Makino Prof. Emeritus, Dokkyo University School of Medicine; Tokyo Allergic Disease Research Institute/Jobu Hospital of Pulmonary Medicine Members (alphabetical order): Dr. Mitsuru Adachi Dr. Yukihiro Ago Dr. Kazuo Akiyama Dr. Minoru Baba Dr. Yosuke Egashira Dr. Masaki Fujimura Dr. Takeshi Fukuda Dr. Kenshi Furusho Dr. Yoji Iikura Dr. Hiroshi Inoue Dr. Koji Ito Dr. Itsuo Iwamoto Dr. Junzaburo Kabe Dr. Yuichiro Kamikawa Dr. Yoshikazu Kawakami Dr. Norio Kihara Dr. Satoshi Kitamura Dr. Koichiro Kudo Dr. Kenji Mano Dr. Takehiko Matsui First Department of Internal Medicine, Showa University School of Medicine National Center of Neurology and Psychiatry (Present Bunkyo Gakuin University) Research Center for Allergy and Rheumatology, National Sagamihara Hospital (Present Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital) Doai Memorial Hospital Tamana Central Hospital (Present Kyushu University of Nursing and Social Welfare) Third Department of Internal Medicine, Kanazawa University School of Medicine Department of Pulmonary Medicine and Clinical Immunology, Dokkyo University School of Medicine Kishiwada City Hospital (Present Kokura Allergy Clinics) Department of Pediatrics, Showa University School of Medicine Third Department of Internal Medicine, Iwate Medical University Department of Allergy and Respiratory Disease, Doai Memorial Hospital (Present Yugawara Kosei-Nenkin Hospital) Clinical Cell Biology, Graduate School of Medicine, Chiba University Yugawara Kosei-Nenkin Hospital (Present Taiheiyo Cement Corp. Clinics) Department of Pharmacology, Dokkyo University School of Medicine First Department of Medicine, Hokkaido University School of Medicine (Present Kohnan Hospital) Kihara Hospital Department of Pulmonary Medicine, Jichi Medical School (Present Minami-Tochigi Hospital) International Medical Center of Japan Department of Internal Medicine, Teikyo University School of Medicine (Present Taikyo College of Medical Technology) Department of Pediatrics, Tokyo Metropolitan Ebara General Hospital Int Arch Allergy Immunol Vol. 136, Suppl. 1, 2005 VII
8 Dr. Haruki Mikawa Dr. Seishiro Miyagi Dr. Terumasa Miyamoto Dr. Yutaka Morita Dr. Yukio Nagasaka Dr. Takemasa Nakagawa Dr. Shigenori Nakajima Dr. Tsugio Nakazawa Dr. Sankei Nishima Dr. Ken Ohta Dr. Takao Okubo Dr. Hiroki Sakakibara Dr. Yasuyuki Sano Dr. Keisuke Shinomiya Dr. Kenzo Takagi Dr. Kiyoshi Takahashi Dr. Gen Tamura Dr. Hisao Tomioka Dr. Kyoichiro Toyoshima Dr. Kazuharu Tsukioka Dr. Nobuo Ueda Dr. Michio Yamakido Prof. Emeritus, University of Kyoto, Kansaidenryoku Hospital Okinawa Chubu Hospital (Present Muribushi-Okinawa, Muribushi Project for Okinawa Residency Program) Prof. Emeritus, University of Tokyo; Japan Clinical Allergy Research Institute Department of Respiratory Medicine, Graduate School of Medicine, University of Tokyo (Present Ochanomizu University) Fourth Department of Internal Medical, Kinki University School of Medicine (Present Department of Medicine and Pulmonology, Kinki University Sakai Hospital) Department of Internal Medicine, St. Marianna University School of Medicine Life Science Research Institute, Kinki University School of Medicine (Present Kinki University Nara Hospital) Gunma University School of Health Sciences National Hospital Organization, Fukuoka National Hospital Department of Medicine, Teikyo University School of Medicine Prof. Emeritus, Yokohama City University; International University of Health and Welfare Division of Pulmonology and Allergology, Fujita Health University School of Medicine Department of Allergy and Respiratory Medicine, Doai Memorial Hospital Former Department of Pediatrics, National Himeji Hospital Nagoya University School of Health Sciences National Hospital Organization, Minami-Okayama Medical Center Department of Respiratory and Infectious Diseases, Tohoku University School of Medicine Prof. Emeritus, Toho University Osaka Prefectural Habikino Hospital (Present Toyoshima Pediatric Clinics) Niigata Allergic Disease Research Institute Ehime Prefectural Central Hospital Second Department of Internal Medicine, Hiroshima University Faculty of Medicine (Present Kure Kyosai Hospital) Collaborators: Dr. Susumu Hosoi Dr. Hironori Sagara Department of Pediatrics, Graduate School of Medicine, Kyoto University (Present Ako City Hospital) Department of Pulmonary Medicine and Clinical Immunology, Dokkyo University School of Medicine VIII Int Arch Allergy Immunol Vol. 136, Suppl. 1, 2005
Asthma Prevention and Management Guidelines
Asthma Prevention and Management Guidelines 1998, Japan (JGL 1998): English version Report of the Research Group for Asthma Prevention and Management Guidelines, supported by the Immunology & Allergy Research
More informationNutrition and Kidney Disease: A New Era
Nutrition and Kidney Disease: A New Era Contributions to Nephrology Vol. 155 Series Editor Claudio Ronco Vicenza Nutrition and Kidney Disease: A New Era Volume Editors Hiromichi Suzuki Saitama Paul L.
More informationTHC:CBD Daily Practice Evidence in MS Spasticity Management: The Moment of Large Databases
THC:CBD Daily Practice Evidence in MS Spasticity Management: The Moment of Large Databases Almirall-Sponsored Satellite Symposium of the 31 st Congress of the European Committee for Treatment and Research
More informationBrain, Stroke and Kidney
Brain, Stroke and Kidney Contributions to Nephrology Vol. 179 Series Editor Claudio Ronco Vicenza Brain, Stroke and Kidney Volume Editor Kazunori Toyoda Osaka 21 figures and 20 tables, 2013 Basel Freiburg
More informationPineal Region Tumors. Diagnosis and Treatment Options
Pineal Region Tumors. Diagnosis and Treatment Options Progress in Neurological Surgery Vol. 23 Series Editor L. Dade Lunsford Pittsburgh, Pa. Pineal Region Tumors Diagnosis and Treatment Options Volume
More informationNeurobiology of Drug Abuse
Neurobiology of Drug Abuse Monographs in Neural Sciences Vol. 13 Series Editor Maynard M. Cohen, Chicago, Ill. KARGER Basel Miinchen. Paris London New York New Delhi Singapore Tokyo Sydney Neurobiology
More informationKarger Basel München Paris London New York New Delhi Singapore -Tokyo Sydney
22 Progress in Respiration Research Editor: H. Herzog A. Zapletal, M. Šamánek, T. Paul Lung Function in Children and Adolescents Lung Function in Children and Adolescents Progress in Respiration Research
More informationThe Developing Testis. Physiology and Pathophysiology
The Developing Testis. Physiology and Pathophysiology Endocrine Development Vol. 5 Series Editor Martin O. Savage London The Developing Testis Physiology and Pathophysiology Volume Editor Olle Söder Stockholm
More informationScientific Aspects of Women s Gymnastics
Scientific Aspects of Women s Gymnastics Medicine and Sport Science Vol. 45 Series Editors J. Borms, Brussels M. Hebbelinck, Brussels A.P. Hills, Brisbane Basel Freiburg Paris London New York New Delhi
More informationDetection, Assessment, Diagnosis and Monitoring of Caries
Detection, Assessment, Diagnosis and Monitoring of Caries Monographs in Oral Science Vol. 21 Series Editors A. Lussi Bern G.M. Whitford Augusta, Ga. Detection, Assessment, Diagnosis and Monitoring of Caries
More informationChronic Myeloproliferative Disorders
Chronic Myeloproliferative Disorders Chronic Myeloproliferative Disorders Cytogenetic and Molecular Genetic Abnormalities Editor Barbara J. Bain, London 15 figures, 4 in color, and 18 tables, 2003 ABC
More informationOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO. Genetic Disorders of Endocrine Neoplasia
Genetic Disorders of Endocrine Neoplasia Frontiers of Hormone Research Vol. 28 Series Editor Ashley B. Grossman London ABC Genetic Disorders of Endocrine Neoplasia Volume Editors P.L.M. Dahia Boston, Mass.
More informationPediatric and Inflammatory Bowel Disease: Perspective and Consequences
Pediatric and Inflammatory Bowel Disease: Perspective and Consequences Pediatric and Adolescent Medicine Vol. 14 Series Editors David Branski Jerusalem Wieland Kiess Leipzig Pediatric and Inflammatory
More informationAttention-Deficit Hyperactivity Disorder (ADHD) in Adults
Attention-Deficit Hyperactivity Disorder (ADHD) in Adults Key Issues in Mental Health Vol. 176 Series Editors A. Riecher-Rössler Basel M. Steiner Hamilton Attention-Deficit Hyperactivity Disorder (ADHD)
More informationDiseases of the Thyroid in Childhood and Adolescence
Diseases of the Thyroid in Childhood and Adolescence Pediatric and Adolescent Medicine Vol. 11 Series Editors Wieland Kiess, Leipzig David Branski, Jerusalem Diseases of the Thyroid in Childhood and Adolescence
More informationActive Middle Ear Implants
Active Middle Ear Implants Advances in Oto-Rhino-Laryngology Vol. 69 Series Editor W. Arnold Munich Active Middle Ear Implants Volume Editor Klaus Böheim St. Pölten 25 figures, 4 in color, and 1 table,
More informationProgress in Experimental Tumor Research
COX-2 Progress in Experimental Tumor Research Vol. 37 Series Editor Joseph R. Bertino, New Brunswick, N.J. Basel Freiburg Paris London New York Bangalore Bangkok Singapore Tokyo Sydney COX-2 A New Target
More informationPathogenesis and Management of Atopic Dermatitis
Pathogenesis and Management of Atopic Dermatitis Current Problems in Dermatology Vol. 41 Series Editors Peter Itin Basel Gregor Jemec Roskilde Pathogenesis and Management of Atopic Dermatitis Volume Editor
More informationDisorders of the Human Adrenal Cortex
Disorders of the Human Adrenal Cortex Endocrine Development Vol. 13 Series Editor P. Mullis Bern Disorders of the Human Adrenal Cortex Volume Editors Christa E. Flück Bern Walter L. Miller San Francisco,
More information17w Dandy Walker Syndrome
17w Dandy Walker Syndrome Anthony J. Raimondi Kiyoshi Sato Takeyoshi Shimoji The JJrnidy-W«lλ er Sωίdrοme 13 figures and 6 tables, 1984 KARGER S. Karger Basel München Paris London New York Tokyo Sydney
More informationEndocrine Control of Skeletal Maturation
Endocrine Control of Skeletal Maturation Ze ev Hochberg Endocrine Control of Skeletal Maturation Annotation to Bone Age Readings 70 figures and 2 tables, 2002 Basel Freiburg Paris London New York New Delhi
More informationPheochromocytoma. Pathophysiology and Clinical Management
Pheochromocytoma. Pathophysiology and Clinical Management Frontiers of Hormone Research Vol. 31 Series Editor Ashley B. Grossman London Pheochromocytoma Pathophysiology and Clinical Management Volume Editor
More informationAntiplatelet Therapy in ACS and A-Fib
Antiplatelet Therapy in ACS and A-Fib Advances in Cardiology Vol. 47 Series Editor Jeffrey S. Borer New York, N.Y. Antiplatelet Therapy in ACS and A-Fib Volume Editors Victor L. Serebruany Towson, Md.
More informationControversies in Pediatric and Adolescent Hematology
Controversies in Pediatric and Adolescent Hematology Pediatric and Adolescent Medicine Vol. 17 Series Editors David Branski Jerusalem Wieland Kiess Leipzig Controversies in Pediatric and Adolescent Hematology
More informationSchizophrenia: Positive and Negative Symptoms and Syndromes
Schizophrenia: Positive and Negative Symptoms and Syndromes Modern Problems of Pharmacopsychiatry Founded 1968 by F.A. Freyhant, N. Petrilowitscht, and P. Pichot Vol. 24 Series Editors T.A. Ban, Nashville,
More informationTextiles and the Skin
Textiles and the Skin Current Problems in Dermatology Vol. 31 Series Editor G. Burg, Zurich Textiles and the Skin Volume Editors Peter Elsner, Jena Kathryn Hatch, Tucson Walter Wigger-Alberti, Jena 66
More informationThe Cytology of Soft Tissue Tumours
The Cytology of Soft Tissue Tumours Monographs in Clinical Cytology Vol.16 Series Editor Svante R. Orell Kent Town The Cytology of Soft Tissue Tumours Måns Åkerman, Patologisk/Cytologisk Klinik, Lund Henryk
More informationFNA Cytology of Soft Tissue and Bone Tumors
FNA Cytology of Soft Tissue and Bone Tumors Monographs in Clinical Cytology Vol. 22 Series Editor Philippe Vielh Dudelange, Luxembourg Henryk A. Domanski Lund Charles S. Walther Lund FNA Cytology of Soft
More informationDiabetes and Cancer. Epidemiological Evidence and Molecular Links
Diabetes and Cancer. Epidemiological Evidence and Molecular Links Frontiers in Diabetes Vol. 19 Series Editors M. Porta Turin F.M. Matschinsky Philadelphia, Pa. Diabetes and Cancer Epidemiological Evidence
More informationUltrasound Imaging in Acute and Chronic Kidney Disease
Ultrasound Imaging in Acute and Chronic Kidney Disease Contributions to Nephrology Vol. 188 Series Editor Claudio Ronco Vicenza Ultrasound Imaging in Acute and Chronic Kidney Disease Volume Editors Mario
More informationLatest Achievements of Diabetes Research Reviewed Contents of 1984's Major Diabetes Congresses
Latest Achievements of Diabetes Research Reviewed Contents of 1984's Major Diabetes Congresses Frontiers in Diabetes Vol. 7 Series Editor F. Belfiore, Catania karger s. Karger Basel Munchen Paris London
More informationPediatric Infectious Diseases
Pediatric Infectious Diseases Pediatric and Adolescent Medicine Vol. 4 Series Editor D. Branski, Jerusalem KAR.GER. Basel Freiburg Paris London New York. New Delhi Bangkok Singapore Tokyo Sydney Pediatric
More informationPrader-Willi Syndrome as a Model for Obesity
Prader-Willi Syndrome as a Model for Obesity This symposium was held in memoriam for Andrea Prader. Drawing of Andrea Prader by his friend and colleague, Emile Gautier, formerly Chairman of the Department
More informationRadiofrequency in Cosmetic Dermatology
Radiofrequency in Cosmetic Dermatology Aesthetic Dermatology Vol. 2 Series Editor David J. Goldberg New York, N.Y. Radiofrequency in Cosmetic Dermatology Volume Editors Moshe Lapidoth Petach Tikva Shlomit
More informationAdvances in Nutrition and Top Sport
Advances in Nutrition and Top Sport Medicine and Sport Science Vol. 32 Series Editors M. Hebbelinck, Brussels R.J. Shephard, Toronto Founder and Editor from 1969 to 1984 E. Jokl, Lexington, Ky. KARG E
More informationVitamin D and Rickets
Vitamin D and Rickets Endocrine Development Vol. 6 Series Editor Martin O. Savage London Vitamin D and Rickets Volume Editor Ze ev Hochberg Haifa 66 figures, 5 in color, and 23 tables, 2003 Basel Freiburg
More informationPhosphate and Vitamin D in Chronic Kidney Disease
Phosphate and Vitamin D in Chronic Kidney Disease Contributions to Nephrology Vol. 180 Series Editor Claudio Ronco Vicenza Phosphate and Vitamin D in Chronic Kidney Disease Volume Editor Mohammed S. Razzaque
More informationProgress in Tumor Research
Immuno-Oncology Progress in Tumor Research Vol. 42 Series Editors Rolf A. Stahel Zurich Solange Peters Lausanne Immuno-Oncology Volume Editors Olivier Michielin Lausanne George Coukos Lausanne 8 figures,
More informationLeukocyte Depletion in Cardiac Surgery and Cardiology
Leukocyte Depletion in Cardiac Surgery and Cardiology Leukocyte Depletion in Cardiac Surgery and Cardiology Editors Georg Matheis Frankfurt Anton Moritz Frankfurt Martin Scholz Frankfurt 32 figures and
More information... Psychoanalysis in Childhood and Adolescence
Psychoanalysis in Childhood and Adolescence.. Psychoanalysis in Childhood and Adolescence Editors Kai von Klitzing, Basel Phyllis Tyson, La Jolla, Calif. Dieter Bürgin, Basel 3 figures, 2000 Kai von Klitzing,
More informationGenetics in Ophthalmology
Genetics in Ophthalmology Developments in Ophthalmology Vol. 37 Series Editor W. Behrens-Baumann, Magdeburg Basel Freiburg Paris London New York Bangalore Bangkok Singapore Tokyo Sydney Genetics in Ophthalmology
More informationControversies in Gastrointestinal Tumor Therapy
Controversies in Gastrointestinal Tumor Therapy Frontiers of Radiation Therapy and Oncology Vol. 38 Series Editors J.L. Meyer San Francisco, Calif. W. Hinkelbein Berlin 6th International Symposium on Special
More information(j) [MOOffij~OO. Modern Problems of Pharmacopsychiatry. Vol. 22. Founded 1968 by F.A. Freyhant, N. Petrilowitscht, and F. Pichot
Anxiety Modern Problems of Pharmacopsychiatry Founded 1968 by F.A. Freyhant, N. Petrilowitscht, and F. Pichot Vol. 22 Series Editors T.A. Ban, Nashville, Tenn.; P. Pichot, Paris; W. Poldinger, Basel (j)
More informationMedicine in Sports Training and Coaching
Medicine in Sports Training and Coaching Medicine and Sport Science Vol. 35 Series Editors M. Hebbelinck, Brussels R.J. Shephard, Toronto, Ont. Founder and Editor from 1969 to 1984 E. Jokl, Lexington,
More informationAcute Kidney Injury From Diagnosis to Care
Acute Kidney Injury From Diagnosis to Care Contributions to Nephrology Vol. 187 Series Editor Claudio Ronco Vicenza Acute Kidney Injury From Diagnosis to Care Volume Editors Xiaoqiang Ding Shanghai Claudio
More informationKAR.GER. Antibiotics and Chemotherapy. Vol. 45. Series Editor H. SchOnfeld, Grenzach
Bacterial Meningitis Antibiotics and Chemotherapy Vol. 45 Series Editor H. SchOnfeld, Grenzach KAR.GER. Basel Miinchen Paris London New York. New Delhi Bangkok Singapore Tokyo Sydney Bacterial Meningitis
More informationSmall for Gestational Age. Causes and Consequences
Small for Gestational Age. Causes and Consequences Pediatric and Adolescent Medicine Vol. 13 Series Editors Wieland Kiess Leipzig David Branski Jerusalem Small for Gestational Age Causes and Consequences
More informationEpidemiology of Injury in Adventure and Extreme Sports
Epidemiology of Injury in Adventure and Extreme Sports Medicine and Sport Science Vol. 58 Series Editors J. Borms Brussels M. Hebbelinck Brussels A.P. Hills Brisbane T. Noakes Cape Town Epidemiology of
More informationUrological Complications in Gynecological Surgery and Radiotherapy
Urological Complications in Gynecological Surgery and Radiotherapy Contributions to Gynecology and Obstetrics Vol. 11 Series Editor P. J. Keller, Zürich ]11Wξ]1 Contributions to S. Karger Basel München
More informationTIA as Acute Cerebrovascular Syndrome
TIA as Acute Cerebrovascular Syndrome Frontiers of Neurology and Neuroscience Vol. 33 Series Editor J. Bogousslavsky Montreux TIA as Acute Cerebrovascular Syndrome Volume Editors S. Uchiyama Tokyo P. Amarenco
More informationCataract Pathogenesis: Results of Epidemiological Studies and Experimental Models
Cataract Pathogenesis: Results of Epidemiological Studies and Experimental Models Developments in Ophthalmology Vol. 26 Κ 8' µ G Ε Ε Basel Freiburg Paris London New York New Delhi Bangkok Singapore Tokyo.
More informationChina's Sports Medicine
China's Sports Medicine Medicine and Sport Science Founder and Editor from 1969 to 1984 E. Jokl, Lexington, Ky. Vol. 28 Series Editors M. Hebbelinck, Brussels R.J. Shephard, Toronto, Ont. KARGDER ΈΜΗ Basel
More informationGenetics in Diabetes Type 2 Diabetes and Related Traits
Genetics in Diabetes Type 2 Diabetes and Related Traits Frontiers in Diabetes Vol. 23 Series Editors M. Porta Turin F.M. Matschinsky Philadelphia, Pa. Genetics in Diabetes Type 2 Diabetes and Related Traits
More informationClinical Pathology of Fibro-Osteo-CementalLesions in the Cranio-Facial and Jaw Bones. A New Approach to Differential Diagnosis
Clinical Pathology of Fibro-Osteo-CementalLesions in the Cranio-Facial and Jaw Bones A New Approach to Differential Diagnosis 281 figures and 24 tables, 1983 Karger S. Karger Basel Mnchen Paris London
More information... Glandular Mechanisms of Salivary Secretion
Glandular Mechanisms of Salivary Secretion.. Frontiers of Oral Biology Vol. 10 Series Editor R.W.A. Linden, London Glandular Mechanisms of Salivary Secretion Volume Editors J.R. Garrett, London J. Ekström,
More informationNew Directions in Tardive Dyskinesia Research
New Directions in Tardive Dyskinesia Research Modern Problems of Pharmacopsychiatry Founded 1968 by F.A. Freyhant, N. Petrilowitscht, and F. Pichot Vol. 21 Series Editors T.A. Ban, Nashville, Tenn.; P.
More informationClinical Pathology of Fibro-Osteo-Cemental Lesions in the Cranio-Facial and Jaw Bones A New Approach to Differential Diagnosis
Clinical Pathology of Fibro-Osteo-Cemental Lesions in the Cranio-Facial and Jaw Bones A New Approach to Differential Diagnosis Μ. Ι/Ίαkek Clinicαl Pathology of Fίbrο-Οsteο-Cementαl Lesions in the Craniο-Fαcία1
More informationBasel München Paris London New York New Delhi Singapore Tokyo Sydney
The Delusional Misidentification Syndromes Bibliotheca Psychiatrica No. 164 Series Editors P. Berner, Wien E. Gabriel, Wien KARGER Basel München Paris London New York New Delhi Singapore Tokyo Sydney The
More informationAn International System for Human Cytogenetic Nomenclature (2013)
ISCN 2013 An International System for Human Cytogenetic Nomenclature (2013) Editors Lisa G. Shaffer Jean McGowan-Jordan Michael Schmid Recommendations of the International Standing Committee on Human Cytogenetic
More informationPharmacological Treatment of Endocrinopathies
Pharmacological Treatment of Endocrinopathies Progress in Basic and Clinical Pharmacology Vol. 5 Series Editors P. Lomax, Los Angeles, Calif. E.S. Vesell, Hershey, Pa. KARGER Basel München Paris. London
More informationKARG E R. Stroke Prevention. Editors Wolfgang Domdorf, Giessen Peter Marx, Berlin. 26 figures and 29 tables, 1994
Stroke Prevention Stroke Prevention Editors Wolfgang Domdorf, Giessen Peter Marx, Berlin 26 figures and 29 tables, 1994 KARG E R Basel Freiburg Paris. London. New York New Delhi. Bangkok Singapore. Tokyo
More informationPerinatal Stress, Mood and Anxiety Disorders
Perinatal Stress, Mood and Anxiety Disorders Bibliotheca Psychiatrica No. 173 Series Editors A. Riecher-Rössler Basel M. Steiner Hamilton Perinatal Stress, Mood and Anxiety Disorders From Bench to Bedside
More informationKey words: Mucocutaneous Lymph Node Syndrome, Incidence Rate, Geographical Distribution, Temporal Distribution, Japan. METHODS
doi:10.2188/jea.je2008030 Original Article Monthly Observation of the Number of Patients with Kawasaki Disease and its Incidence Rates in Japan: Chronological and Geographical Observation from Nationwide
More informationRegulation of the IgE Antibody Response
Regulation of the IgE Antibody Response Progress in Allergy vaι. s2 Series Editors Kimishige Ishizaka, Baltimore, Md.; Paul KaΙΙόs, Helsingborg; Byron H. Waksman, New York, N.Y., and Alain L. de Weck,
More informationItch Management in Clinical Practice
Itch Management in Clinical Practice Current Problems in Dermatology Vol. 50 Series Editors Peter Itin Basel Gregor B.E. Jemec Roskilde Itch Management in Clinical Practice Volume Editors Jacek C. Szepietowski
More informationOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO. Hysteroscopy. State of the Art
Hysteroscopy. State of the Art Contributions to Gynecology and Obstetrics Vol. 20 Series Editor Ossi R. Köchli, Basel ABC Basel W Freiburg W Paris W London W New York W New Delhi W Bangkok W Singapore
More informationObesity and Binge Eating Disorder
Obesity and Binge Eating Disorder Bibliotheca Psychiatrica No. 171 Series Editors Anita Riecher-Rössler Meir Steiner Hamilton Basel Obesity and Binge Eating Disorder Volume Editors Simone Munsch Basel
More informationLeksell Gamma Knife Society
Proceedings of the 9th International Meeting of the Leksell Gamma Knife Society Hong Kong, November 1998 Editors J.C. Ganz, Graz Ph.L. Gildenberg, Houston, Tex. P.O. Franklin, Houston, Tex. 55 figures
More informationFine Needle Aspiration of Bone Tumours
Fine Needle Aspiration of Bone Tumours Monographs in Clinical Cytology Vol. 19 Series Editor Svante R. Orell Kent Town Fine Needle Aspiration of Bone Tumours The Clinical, Radiological, Cytological Approach
More informationCleft Lip and Palate
Cleft Lip and Palate Frontiers of Oral Biology Vol. 16 Series Editor Paul T. Sharpe London Cleft Lip and Palate Epidemiology, Aetiology and Treatment Volume Editor Martyn T. Cobourne London 28 figures
More informationThe current evidence of dental care and oral health for achieving healthy longevity in an aging society 2015
The current evidence of dental care and oral health for achieving healthy longevity in an aging society 2015 Appendix Summaries of selected research Japan Dental Association Japan Dental Association URL
More informationIntracranial Atherosclerosis: Pathophysiology, Diagnosis and Treatment
Intracranial Atherosclerosis: Pathophysiology, Diagnosis and Treatment Frontiers of Neurology and Neuroscience Vol. 40 Series Editor J. Bogousslavsky Montreux Intracranial Atherosclerosis: Pathophysiology,
More informationCurrent Research in Head and Neck Cancer
Current Research in Head and Neck Cancer Advances in Oto-Rhino-Laryngology Vol. 62 Series Editor W. Arnold Munich Current Research in Head and Neck Cancer Molecular Pathways, Novel Therapeutic Targets,
More informationDiabetic Retinopathy
Diabetic Retinopathy Developments in Ophthalmology Vol. 39 Series Editor W. Behrens-Baumann, Magdeburg Diabetic Retinopathy Volume Editor Gabriele E. Lang, Ulm 35 figures, 3 in color, and 25 tables, 2007
More informationCurrent state and need for improvement of system for antibody testing and counseling for HIV infection at public health centers in Japan
J Med Dent Sci 2005; 52: 177 182 Original Article Current state and need for improvement of system for antibody testing and counseling for HIV infection at public health centers in Japan Chika Miyazaki
More informationThe Development of Intentional Action. Contributions to Human Development
The Development of Intentional Action Contributions to Human Development Vol. 22 Series Editor Deanna Kuhn, New York, N.Y. KARGER Basel Munchen Paris London NewYork. New Delhi Bangkok Singapore Tokyo Sydney
More informationFluorescent Imaging: Treatment of Hepatobiliary and Pancreatic Diseases
Fluorescent Imaging: Treatment of Hepatobiliary and Pancreatic Diseases Frontiers of Gastrointestinal Research Vol. 31 Series Editor Choitsu Sakamoto Tokyo Fluorescent Imaging Treatment of Hepatobiliary
More informationEndocrine Immunology
Endocrine Immunology Frontiers of Hormone Research Vol. 48 Series Editor Ezio Ghigo Turin Co-Editor Federica Guaraldi Turin Endocrine Immunology Volume Editors Wilson Savino Rio de Janeiro Federica Guaraldi
More informationTuberculosis Surveillance Center-RIT/JATA TUBERCULOSIS IN JAPAN
Tuberculosis Surveillance Center-RIT/JATA J a p a n TUBERCULOSIS IN JAPAN ANNUAL REPORT 2016 About the Tuberculosis Surveillance Center The Tuberculosis Surveillance Center, located within the Department
More informationAlopecias Practical Evaluation and Management
Alopecias Practical Evaluation and Management Current Problems in Dermatology Vol. 47 Series Editors Peter Itin Basel Gregor B.E. Jemec Roskilde Alopecias Practical Evaluation and Management Volume Editors
More informationAdvances in Biological
Depressive Illness Advances in Biological Psychiatry Vol. 7 Series Editors J. Mendlewicz, Brussels, and H.M. van Praag, Utrecht S. Karger' Basel. Miinchen. Paris' London' New York' Sydney Symposium on
More informationTopical Glucocorticoids with Increased Benefit/Risk Ratio. Current Problems in Dermatology. Vol. 21. Series Editor G. Burg, Zurich
Topical Glucocorticoids with Increased Benefit/Risk Ratio Current Problems in Dermatology Vol. 21 Series Editor G. Burg, Zurich KARGER Basel Freiburg Paris London New York New Delhi Bangkok Singapore Tokyo
More informationThe Craniocervical Syndrome and MRI
The Craniocervical Syndrome and MRI The Craniocervical Syndrome and MRI Editors Francis W. Smith Jay S. Dworkin London Melville, N.Y. 75 figures, 8 in color, 7 tables, and online supplementary material,
More informationHandbook of. Nephrology. Irfan K. Moinuddin, MD. David J. Leehey, MD
Handbook of Nephrology First Edition Irfan K. Moinuddin, MD Assistant Professor of Medicine Southern Illinois University Springfield, Illinois David J. Leehey, MD Professor of Medicine Loyola University
More informationBasel München Paris London New York New Delhi Bangkok Singapore Tokyo Sydney
Endothelial Cell Function in Diabetic Microangiopathy: Problems in Methodology and Clinical Aspects Frontiers in Diabetes Vol. 9 Series Editor F. Belfiore, Catania KARGER Basel München Paris London New
More informationThe Chemical Languages of the Nervous System
The Chemical Languages of the Nervous System Josef Donnerer Fred Lembeck THE CHEMICAL LANGUAGES OF THE NERVOUS SYSTEM HISTORY OF SCIENTISTS AND SUBSTANCES 6 figures, 1 in color, 2006 III Basel Freiburg
More informationBone Marrow Biopsies Updated
Bone Marrow Biopsies Updated Bibliotheca Haematologica Haematologíca rτo. No. 50 Series Editor A. Hässig, Bern Haematologica S.Karger Basel München Paris London NewYork Tokyo Sydney Satellite Symposium
More informationComplications in Neurosurgery I
Complications in Neurosurgery I Progress in Neurological Surgery VOI.11 Series Editor A. M. Landolt, Zürich Editorial Board P. Derome, La Celle-Saint Cloud; J. C. de Villiers, Cape Town; H. Kikuchi, Osaka;
More informationStroke. Natan M. Bornstein Tel Aviv. Practical Guide for Clinicians. Editor. Section Title. 18 figures, 4 in color, and 35 tables, 2009
Stroke Section Title Stroke Practical Guide for Clinicians Editor Natan M. Bornstein Tel Aviv 18 figures, 4 in color, and 35 tables, 2009 Basel Freiburg Paris London New York Bangalore Bangkok Shanghai
More informationjournal Ebisawa et al. World Allergy Organization Journal (2015) 8:11 DOI /s
Ebisawa et al. World Allergy Organization Journal (2015) 8:11 DOI 10.1186/s40413-015-0062-3 journal ORIGINAL RESEARCH Open Access Intermittent and episode-driven use of pranlukast to reduce the frequency
More informationSports Endocrinology
Sports Endocrinology Frontiers of Hormone Research Vol. 47 Series Editor Ezio Ghigo Turin Co-Editor Federica Guaraldi Turin Sports Endocrinology Volume Editors Fabio Lanfranco Turin Christian J. Strasburger
More informationPrevention of Coronary Heart Disease From the Cholesterol Hypothesis to ω6/ω3 Balance
Prevention of Coronary Heart Disease From the Cholesterol Hypothesis to ω6/ω3 Balance World Review of Nutrition and Dietetics Vol. 96 Series Editor Artemis P. Simopoulos The Center for Genetics, Nutrition
More informationLaparoscopic Hernia Repair: Α New Standard?
Laparoscopic Hernia Repair: Α New Standard? Progress in Surgery Vol.21 Series Editors M.W. Büchler, Bern E.H. Farthmann, Freiburg i. Br. ~/ A Basel Freiburg Paris London New York ΚΑ R C R New Delhi Bangkok
More informationConsultation-Liaison Psychiatry in Germany, Austria and Switzerland
Consultation-Liaison Psychiatry in Germany, Austria and Switzerland Advances in Psychosomatic Medicine Vol. 26 Series Editor T.N. Wise Falls Church, Va. Editors G.A. Fava Bologna I. Fukunishi Tokyo M.B.
More informationNew Insights in Intracerebral Hemorrhage
New Insights in Intracerebral Hemorrhage Frontiers of Neurology and Neuroscience Vol. 37 Series Editor J. Bogousslavsky Montreux New Insights in Intracerebral Hemorrhage Volume Editors Kazunori Toyoda
More informationHistopathology of Chronic Constipation
Histopathology of Chronic Constipation Histopathology of Chronic Constipation William A. Meier-Ruge, Basel Elisabeth Bruder, Basel 105 figures, 93 in color, 6 tables, 2012 Basel Freiburg Paris London New
More informationPediatric Ear Diseases
Pediatric Ear Diseases Yasushi Naito Pediatric Ear Diseases Diagnostic Imaging Atlas and Case Reports 242 figures, 7 in color and 5 tables, 2013 Basel Freiburg Paris London New York New Delhi Bangkok
More informationNews Release. Identification of the cause of chronic active Epstein Barr virus (EBV) infection and the mechanism by which EBV causes cancer
News Release Title Identification of the cause of chronic active Epstein Barr virus (EBV) infection and the mechanism by which EBV causes cancer Key Points A research group in Japan, led by Dr. Hiroshi
More informationIAEA/RCA Regional Training Course on Theragnostics and Dementias
International Atomic Energy Agency Department of Technical Cooperation And Nuclear Medicine and Diagnostic Imaging Section Division of Human Health TN-RAS6083-1702276 IAEA/RCA Regional Training Course
More informationPathology of Chronic Constipation in Pediatric and Adult Coloproctology
Pathobiology 2005;72:1 106 DOI: 10.1159/000082310 Pathology of Chronic Constipation in Pediatric and Adult Coloproctology William A. Meier-Ruge, Basel Elisabeth Bruder, Basel 213 figures, 186 in color,
More information