- WG7 INTERNAL DOSIMETRY -

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1 EURADOS General Assembly (AM2016) Politecnico di Milano, February 10, WG7 INTERNAL DOSIMETRY - Network, Research, Dissemination of knowledge M.A. Lopez (CIEMAT, Spain) 1

2 WG7 INTERNAL DOSIMETRY Network Chairperson: Maria Antonia Lopez (CIEMAT, Spain) Secretary: Augusto Giussani (BfS, Germany) Task-coordinators: D. Nosske, BfS(7.2/7.3), D. Franck, IRSN & AL Lebacq, SCK-CEN (7.4), E. Blanchardon, IRSN (T.5), G. Etherington, PHE (7.6), W. Hofmann, Univ. Salzburg & W. Li, HMGU (7.7) and M.A. Lopez CIEMAT & A. Giussani, BfS(7.8) 35 Full members 63 Corresponding members 37 institutes of 21 countries Europe, America and Asia Link with ICRP: D. Nosske, G. Etherington, A. Giussani, E. Blanchardon, James W.Marsh Link withiso: P. Bérard, CEA Link with USTUR (DOE, USA): S. Tolmachev, USTUR Link withwho REMPAN: C. Li, HealthCanada Link with IAEA: R. Cruz-Suarez 2

3 WG7 BUDGET 2015: WG7 meetings TECHREC budget Date Topic and Location of the meeting Nº participants Costs ( ) February 2015 AM2015, WG7 (plenary) meeting + TECHREC meeting. Dubrovnik, April2015 July2015 TECHREC meeting IM2015, Bruges, Belgium TECHREC meeting CIEMAT, Madrid, Spain September 2015 WG7 (plenary) + TECHREC Meeting SSM, Stockholm, Sweden October 2015 Task-group 7.2/7.3 meeting CEA, Saclay, France November 2015 WG6 meeting (+ Task 7.7) IRSN, Fontenay-aux-Roses, France February 2016 AM2016, WG7 (plenary) meeting + TECHREC meeting. Milano, Italy February2016 TECHREC meeting. KIT, Karlsruhe, Germany September 2016 WG7 meeting, Oxford, UK 1st Europ. Radiat. Protection Week WG7+ TECHREC 11 TECHREC Budget 11 TECHREC Budget WG7+ TECHREC TECHREC Budget

4 WG7 Internal Dosimetry WORK PLAN Task 7.2./7.3- Implementation and QA of BiokineticModels. D. Nosske (BfS, Germany). Task Individual Monitoring and application of Monte Carlo methods to in-vivo monitoring. Radiological and Nuclear emergencies. D.Franck / A.L.Lebacq(SCK-CEN) Cathymara Project, (Chair: D. Broggio, IRSN, France) Task Uncertainty on Dose Assessments - E. Blanchardon (IRSN, Fr) Task Training on Internal Dosimetry G. Etherington (PHE, UK). TECHREC Project, May (Chair: G. Etherington, PHE, UK) Task Internal Microdosimetry. Collaboration with WG6 Computational Dosimetry W. Hofmann (Univ. Salzburg, Austria) / W. Li (HMGU, Germany Task Biodosimetryin case of accidental internal exposures. (WG10+WG7). M.A. Lopez (CIEMAT, Spain) / A. Giussani (BfS, Germany) 4

5 WG7 Internal Dosimetry WORK PLAN Task Update of IDEAS Guidelines. CM. Castellani (ENEA, Italy) IM2015 (Castellani et al) Rad Prot Dosimetry(2015) doi: /rpd/ncv457 EURADOS Report , translation to Spanish (SEPR, 2016) NEW: EURADOS Intercomparison on Dose Assessments when? to be discussed after publication of TECHREC and ICRP/OIR Reports Task 7.2 / Implementation and QA of BiokineticModels. D. Nosske, BfS(Germany) ICRP OIR (Occupational Intakes of Radionuclides) Reports I,II, III, IV, V OIR, Part I: ICRP130 (2015) ICRP Publication 130. Occupational Intakes of Radionuclides: Part 1. Ann. ICRP 44(2), F. Paquet, G. Etherington, M.R. Bailey, R.W. Leggett, J. Lipsztein, W. Bolch, K.F. Eckerman, J.D. Harrison NEW:Task-groupon Guidanceontheimplementationof ICRP OIR Models. H-3, Cs, EURADOS Report 2017 Improving the CONRAD DTPA therapy model. Meeting at CEA Oct-2015 A. Giussani/M. Kastl(HMGU and BfS, Germany) + CEA (France) 5

6 WG7 Internal Dosimetry WORK PLAN Task Individual Monitoring and Application of Monte Carlo Methods to in-vivo monitoring Coordination: D. Franck (IRSN,France) / A.L. Lebacq(SCK-CEN,Belgium) (I) In-vivo Intercomparisonof 241 Am in 3 Skull phantoms ( ) END - Coordination: P. Nogueira(HMGU, Germany). Radiation Measurements (2015) EURADOS YOUNG SCIENTIST AWARD 2015 (AM2016) - Annual Meeting of the Health Physics Society USTUR Session, Spokane (WA, USA). July M.A. Lopez (CIEMAT, Spain) (II) Monte Carlo simulation of in-vivo monitoring of 241 Am in Voxel Skull Phantoms using Ge detectors. Joint WG7-WG6 Action END- - Coordinator: T. Vrba (CTU-Prague) BEST POSTER AWARD IM2015 6

7 WG7 Internal Dosimetry WORK PLAN Task Cont. (III) EURADOS Survey on in-vivo monitoring data of exposed foreigners in Japan,obtained in their respective countries at early stage after the nuclear accident of Fukushima Daiichi NPP. END M.A. Lopez, D. Franck, P. Fojtik, J. Osko - IAEA2014 International Conference on Fukushima NPP accident, Feb EURADOS AM2015. Winter School, Dubrovnik, Feb-2015 ( - RENEB2015 Biodosimetry Network (ISS, Rome, Italy) IM2015(Lopez et al.) Rad Prot Dosimetry (2015) doi: /rpd/ncv510 - IRPA 2016, Cape Town, Southafrica: EARLY MEASUREMENTS OF GENERAL PUBLIC AFTER THE FUKUSHIMA DAIICHI NPP ACCIDENT: DATA MADE 7 AVAILABLE TO THE EURADOS SURVEY. P. Fojtik, D. Franck, M.A. Lopez, J. Osko

8 Task 7.4 (cont.) OPERRA (EC FP7) Call: CAThyMARA Project( ) APPROVED Chair: D. Broggio (IRSN, France) NEW NEW - Child and Adult Thyroid Monitoring After Reactor Accident -Kick-off meeting at IRSN in January 2016 EURADOS Report: Monte Carlo Applicationsto in-vivo monitoringof radionuclides. Coordination: T, Vrba, CTU-Prague (WG6+WG7) NEW WG7 Internal Dosimetry WORK PLAN LLNL (USA)/EURADOS Thyroid Radioiodine Monitoring Progam(TRIP) D. Hickman/Lori Collins (LLNL) & D. Franck /M.A. Lopez(EURADOS) IAEA/ANSI thyroid calibration neck phantom and NIST-traceableisotopes for 125 I and 131 I -21 participants (17 Europe, 2 Asia, 2 America) March EURADOS Intercomparisons: Knee, USTUR Leg, Lungs, Skull - EURADOS/KIT Training Course 8

9 WG7 Internal Dosimetry WORK PLAN Task 7.5.-Uncertainties on dose assessments Coordinator: E. Blanchardon (IRSN) NEW Dosimetry of workers addressed in connection with epidemiology studies. Objective: In the frame of an epidemiological study of occupational exposure to uranium, to validate the dose assessment protocol, to identify sources of uncertainty, and to discuss the assessment of uncertainty on dose. Exercise: to calculate lifetime doses for 3 uranium workers (deadline 30/6/15) Main objective: to review different approaches of thedose assessment process in order to feed the discussion on the assessment of dosimetricuncertainties. To reveal items missed inthedosimetry protocol of CURE Project to try to improve it in future projects. 9

10 WG7 Internal Dosimetry WORK PLAN Task Training on Internal Dosimetry. TECHREC Project Coordinator: G. Etherington(PHE, UK) - TC Fundamentals of internal dosimetry postponed - EURADOS-KIT TC on Monte Carlo calibration of WBC, 2014 IM2015(Breustedt et al.) Rad. Protect. Dosimetry 2016 New editionof thecourse? To be discussed TECHREC Project: Establishment of Technical Recommendations for Monitoring Individuals for Occupational Intakes of Radionuclides EC DG ENER ( ) Project Leader: George Etherington (PHE, UK) IM2015 (Etherington et al) Rad Protect Dosimetry 2015 doi: /rpd/ncv395 Presentation of TECHREC at Art 31 Group of Experts meeting, Luxembourg Nov nd Consultation Draft sent for comments on December-2015 Final TECHREC EC Report: May Available (open access) by the end of

11 WG7 Internal Dosimetry WORK PLAN Task Internal Microdosimetry Coordination: W. Hofmann (Univ. Salzburg, Austria) / W. Li (HMGU,Germany) Collaboration with WG6 Computational Dosimetry TG-Micro and Nano dosimetry Joint meeting in Paris (November 2016) Application of computational nanodosimetry to gold nanoparticles in diagnosis and therapy Microdosimetry of inhaled alpha emitters at low doses Balasz Mada(MTA-EK) - Microdosimetry of alpha-particles emitted by radon progeny for modelling the induction of mutations and hyperplasia in the bronchial epithelium EURADOS YOUNG SCIENTIST AWARD 2015 (AM2016) - * CONCERT CALL, TOPIC 1 11

12 EURADOS WG7 - Internal Dosimetry Task Biodosimetry in case of accidental internal exposures Coordination/Editorial team: WG10: H. Romm (BfS) / A. Testa(ENEA) WG7: M.A. Lopez (CIEMAT) / A. Giussani (BfS) Review on the use of biodosimetrymethods and internal dosimetry evaluations in scenarios involving internal exposures. 10 case scenario studies. Publication in process 1 st draft was discussed in Milano The contact persons of each case (1 WG10 & 1 WG7) will be contacted for agreement in the content of the manuscript Final revision by all WG10/WG7 participants of this joint study: summer 2016 Preliminary conclusions and gaps: Proper dosimetric quantities are required to be compared with the biological endpoints Special models must be developed for reliable blood dosimetry, to determine the blood dose and to know how this quantity correlates with the information provided by biological assays. Clinic studies: experiments can be conducted in cooperation with nuclear 12 medicine units (e.g. ENEA Study A. Testa)

13 EURADOS WG7 - Internal Dosimetry NEXT WG7 MEETING: - Radiation Protection Week: September, 20-23, Oxford, UK Contact person: Simon Bouffler(PHE, UK) In the light of greater integration of European research on Radiation Protection demonstrated by the CONCERT European Joint Programme, the RPW2016 will be organized on September in Oxford, UK. The meeting will bring together complementary strands of radiation protection research, with the established European platforms MELODI, EURADOS, NERIS and ALLIANCE as coorganisers, along with other relevant areas. - EURADOS WG7 meeting: 19 September

14 EURADOS WG7 Publications 2015 (1) 1.- PARAMETER UNCERTAINTYANALYSIS OF A BIOKINETIC MODEL OF CAESIUM W. B. Li, W. Klein, E. Blanchardon, M. Puncher, R.W. Leggett, U. Oeh, B. Breustedt, D. Noßke, M. A. Lopez. Radiat. Prot. Dosim. 163, 37-57(2015) 2.- LESSONS LEARNED FROM THE EURADOS SURVEY ON INDIVIDUAL MONITORING DATA AND INTERNAL DOSE ASSESSMENTS OF FOREIGNERS EXPOSED IN JAPAN FOLLOWING THE FUKUSHIMA DAIICHI NPP ACCIDENT. M. A. Lopez, P. Fojtik, D. Franck, J. Osko, U. Gerstmann, C. Scholl, A.L. Lebacq, B. Breustedt, L. del Risco Norrid. Radiat. Prot. Dosim. doi: /rpd/ncv510(2015) 3.-TECHNICAL RECOMMENDATIONS FOR MONITORING INDIVIDUALS FOR OCCUPATIONAL INTAKES OF RADIONUCLIDES. G. Etherington, P.Bérard, E. Blanchardon, B. Breustedt, CM Castellani, C. Challethosn de Vathaire, A. Giussani, D. Franck, M.A. Lopez, J.W. Marsh, D. Nosske. Radiat. Prot. Dosim. doi: /rpd/ncv395 (2015) 4.- EURADOS-IDEAS GUIDELINES (VERSION 2) FOR THE ESTIMATION OF COMMITTED DOSES FROM INCORPORATION MONITORING DATA. CM Castellani, J.W. Marsh, C. Hurtgen, E. Blanchardon, P. Bérard, A. Giussani, M.A. Lopez, Radiat. Prot. Dosim. 14 doi: /rpd/ncv457(2015)

15 EURADOS WG7 Publications 2015 (2) 5.-EURADOS 241 Am skullmeasurementintercomparison P. Nogueira, W. Rühm, M.A. Lopez, T. Vrba, RW. Buchholz, P. Fojtik, G. Etherington, D. Broggio, J. Huikari, O. Marzocchi, D. Leone, J. Scott, A. Shutt, B. Hauck, K. Capello, B. Perez, JF Navarro. S.Y. Tolmachev. Radiation Measurements (2015) 6.-EURADOS intercomparisonexercise on MC modelling for the in-vivo monitoring of Am-241 in skull phantoms (Part II and III). Vrba Tomas, Broggio David, Caldeira Margarida, Capello Kevin, Fantinova Karin, Franck Didier, Gomez-Ros, Jose Maria, Hunt John, Kinase Sakae, Leone Debora, Lombardo Pasquale Alessandro, Manohari Murugan, Marzocchi Olaf, Moraleda Montserrat, Nogueira Pedro, Ośko Jakub, Arron Shutt,Suhl Soheigh, Takahashi Masa, Teles Pedro, Tremblay Marilyn, Tymińska Katarzyna, Lopez Maria Antonia, Tanner Rick. Radiation Physics and Chemistry 113(2015) 7.-Counting 241 Am in thebfs Human skullphantomoncontact Evaluationin thehuman MonitoringLaboratory. C. Li, P. B. Hauck, K. Capello, P. Nogueira, M.A. Lopez, G.H. Kramer. Health Physics(2015) 15

16 THANKS FOR YOUR ATTENTION!