XSIGHT LUNG TRACKING SYSTEM

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1 XSIGHT LUNG TRACKING SYSTEM

2 CYBERKNIFE SYSTEM HIGHLIGHTS Continual image guidance Without the need for staff intervention or treatment interruption, the CyberKnife s revolutionary image guidance technology continuously works in concert with the treatment delivery system to automatically track, detect and correct managing even the slightest target movements throughout the entire treatment. A COMPLETE ROBOTIC RADIOSURGERY SYSTEM The Accuray CyberKnife System allows clinicians to provide patients with more accurate treatments and an improved quality of life: Synchrony Respiratory Tracking System Linear Accelerator Light weight 6MV Continuously synchronizes beam delivery to X-band linear accelerator with an output of the motion of the tumor, allowing clinicians 800 MU/min, accurately delivers highly to significantly reduce margins while collimated beams of radiation providing eliminating the need for gating or breathholding superior conformality when treating patients. techniques. MultiPlan Treatment Planning System Xsight Lung Tracking System Tracks the This intuitive workflow-based workstation movement of the lung tumors directly, designed for radiosurgery, enables the without fiducials, with accuracy, reliability and creation of plans that have excellent self-adjusting repeatability. conformality and coverage with steep dose Xsight Spine Tracking System Eliminates gradients. the need for surgical implantation of fiducials Sequential Optimization With our userdefined, by using the bony anatomy of the spine to sequentially prioritized planning automatically locate and track tumors with objectives, treatment plans are custom sub-millimeter accuracy. tailored to the unique clinical characteristics of each patient. Iris Variable Aperture Collimator Using tungsten leaves to rapidly manipulate 4D Treatment Optimization and Planning beam geometry, the Iris Collimator enables System Takes into account not only the treatments of unrivaled conformality and movement of the target but also the unparalleled preservation of healthy tissue. movement and deformation of the surrounding tissue. Xchange Robotic Collimator Changer Automatically exchanges collimator sizes, Monte Carlo Dose Calculation Often allowing for highly conformal treatments to considered the gold standard dose be delivered more efficiently. calculation, the CyberKnife System s Monte Carlo Dose Calculation produces results RoboCouch Patient Positioning System in minutes compared to what typically Robotically aligns patients accurately with six requires hours or days with other systems. degrees of freedom, reducing patient setup times and enabling faster treatments. Flexible robotic maneuverability Driven by continual imaging and intelligent motion corrections, the CyberKnife s robotic manipulator automatically positions the linear accelerator to an unprecedented range of positions allowing for access to virtually any tumor from any direction. Dynamic motion targeting With constant updates of target position throughout the respiratory cycle, the CyberKnife System delivers beams synchronized in realtime to targets that move with respiration while adapting to changes in breathing patterns delivering highly conformal radiation with considerably smaller margins and unprecedented accuracy. Unrivaled dose conformality Unconstrained by clockwise/counter-clockwise gantry rotations, the robotic mobility of the CyberKnife System delivers diverse non-coplanar and non-isocentric treatments to precisely sculpt radiosurgical doses to the unique contours of the target.

3 XSIGHT LUNG TRACKING SYSTEM Seamless integration of the Xsight Lung Tracking System into the MultiPlan Treatment Planning System demonstrating a contoured right upper lobe lung tumor. Accuray introduces the Xsight tracking system, a breakthrough in tracking technology. The Xsight System is the only system that uses internal anatomy to directly track targets with radiosurgery accuracy and precision without the need for external frames or implanted fiducials. Breakthrough in tracking technology The Xsight Lung Tracking System delivers the ultimate in soft tissue tracking technology. Unlike anything ever introduced into the radiation oncology market, the Xsight Lung Tracking System uses the actual image intensity of the lung tumor for targeting the beam. By tracking the tumor directly, clinicians can use radiosurgery to treat lung tumors with confidence while minimizing dose to adjacent healthy tissue.

4 The CyberKnife System is the only system that uses internal anatomy to directly track targets using both the Xsight Lung Tracking System and Synchrony Respiratory Tracking Systems making lung radiosurgery completely non-invasive. Radiosurgery accuracy with no fiducials The Xsight Lung Tracking System eliminates the need for invasive placement of radiographic markers, such as fiducials, in the delivery of many lung radiosurgery treatments. The Xsight Lung Tracking System registers directly to the tumor to track, detect and correct for tumor movement in real-time throughout the treatment. A comprehensive tracking system A truly easy to use, non-invasive system, the Xsight Lung Tracking System provides a highly accurate, comfortable alternative for patients and facilitates faster, less complex treatments for clinicians. The Xsight Lung Tracking System is designed to work seamlessly with the Synchrony Respiratory Tracking System, allowing patients to breathe normally while delivering unparalleled accuracy of less than 1.5mm.* The Xsight Lung Tracking System uses advanced, highly sophisticated image processing and image registration techniques to automatically lock onto the tumor directly, tracking it throughout the entire procedure. This tracking innovation enables clinicians to easily treat patients without implanting fiducials. Based on observations and analysis of clinical patient data, the Xsight Lung Tracking System is able to track most peripherally located lung tumors that are at least 15mm in diameter.* These peripheral tumor sites are also the most challenging areas for placing fiducials within the lung. Clinical benefits include: Provides a completely non-invasive treatment alternative for medically inoperable patients Intelligently tracks, detects and corrects for tumor

5 XSIGHT LUNG TRACKING SYSTEM The Xsight Lung Tracking System uses the CyberKnife System s intelligent robotics to track, detect and correct for unpredicted lung tumor motions as seen here. Before Correction. After Correction. movement with continual image guidance throughout the treatment Eliminates invasive fiducial procedures decreasing time to treatment Eliminates the risk of pneumothorax and other complications of fiducial placement Tracks with unparalleled accuracy (less than 1.5mm)* Is fully integrated with the Synchrony Respiratory Tracking System Dynamically tracks targets that move with respiration Minimizes irradiation of healthy tissue and critical structures Allows patients to breathe normally no complex gating or painful breath-holding techniques *Data on file. The CyberKnife System and CyberKnife options may not be available in some countries. For a complete list of CyberKnife Systems and options available, please contact Accuray at sales@accuray.com.

6 ACCURAY INCORPORATED Accuray s philosophy, Our Business Begins with Patients TM, drives the company s commitment to advancing the field of robotic radiosurgery through innovation, while also establishing its products as the standard of care. Accuray s success is measured by the success of its customers in delivering the most advanced care to their patients. Medical institutions worldwide have expanded their clinical programs using Accuray s CyberKnife Robotic Radiosurgery System by treatingpatients that may have been considered untreatable, while building a more comprehensive oncology practice. To this end, Accuray has developed collaborative partnerships with clinicians, researchers and patients. These partnerships help educate clinicians and patients on the benefits of robotic radiosurgery, enabling Accuray to refine and upgrade its technology based on user and patient feedback. This feedback allows Accuray to develop innovative programs that improve clinician s success while differentiating Accuray from traditional medical device companies. The result, the CyberKnife Robotic Radiosurgery System, a pain-free treatment alternative for patients that eliminates invasive surgery and results in a significantly improved quality of life for cancer patients the world over. UNITED STATES ASIA EUROPE Accuray Corporate Headquarters 1310 Chesapeake Terrace Sunnyvale, CA USA Tel: Toll Free: Fax: sales@accuray.com TomoTherapy 1240 Deming Way Madison, WI USA Tel: Fax: Accuray Japan K.K. - Tokyo Daini Tekko Building 6F Marunouchi, Chiyoda-ku Tokyo Japan Tel: Fax: Accuray Asia Ltd. - Hong Kong Suites , Tower 6 The Gateway, Harbour City 9 Canton Road, T.S.T. Hong Kong Tel: Fax: Chengdu Twin-Peak Accelerator Technology #39 Huatai Road, Longtan Industrial Zone, Section 2 East, 3rd Ring Road, Chengdu, Sichuan China Accuray Europe Tour Atlantique 25e 1 Place de la Pyramide Paris La Défense Cedex France Tel: Fax: Tomotherapy Belgium BVBA Pegasuslaan Diegem Belgium Tel: +32 (0) Fax: +32 (0) / Accuray Incorporated. All Rights Reserved. Accuray, the stylized logo, CyberKnife, Synchrony, Xsight, Xchange and RoboCouchare trademarks and/or registered trademarks of Accuray Incorporated in the United States and other countries D

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