Louisiana Cancer Facts & Figures, Liver and Intrahepatic Bile Duct Cancer, 2016

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1 Louisiana Cancer Facts & Figures, Liver and Intrahepatic Bile Duct Cancer, 16 Louisiana Tumor Registry March, 17

2 Liver and Intrahepatic Bile Duct Cancer Liver and intrahepatic bile duct cancer was the 4th most common cancer and the nd leading cause of cancer death in Louisiana from 9 to Between 9 and 13, the average annual incidence rate of Liver and Intrahepatic Bile Duct Cancer was 8. per 1, population in Louisiana and 7.6 per 1, population in the U.S. Between 9 and 13, the average annual mortality rate of Liver and Intrahepatic Bile Duct Cancer was 7.9 per 1, population in Louisiana and 6.1 per 1, population in the U.S. 1. Data source: NCI state cancer profile.. Data source: National Cancer Institute, State Cancer Profiles.

3 Liver and Intrahepatic Bile Duct Cancer: Age-Specific Incidence Rates, Louisiana, 9-13 Rate Per 1, White Male Black Male White Female Black Female Age at Diagnosis

4 Rate Per 1, Liver and Intrahepatic Bile Duct Cancer: Age-Specific Incidence Rates by Gender, 9-13 LA Male U.S. Male LA Female U.S. Female Age at Diagnosis U.S. data source: 18 SEER registries.

5 Rate per 1, Liver and Intrahepatic Bile Duct Cancer: Age-Specific Incidence Rates by Race, 9-13 LA White U.S. White LA Black U.S. Black Age at Diagnosis U.S. data source:18 SEER registries.

6 Liver and Intrahepatic Bile Duct Cancer: Incidence Rates 1,, % U.S. Louisiana Rate Per 1, % 3.9 %* % 4.6 White Male Black Male White Female Black Female 1 Age-adjusted to the U.S. standard population. U.S. Incidence data source: 18 SEER registries. * Incidence rate of Louisiana is significantly different from that of the U.S.

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8 Rate per 1, Liver and Intrahepatic Bile Duct Cancer Incidence Rates 1, by Region: Louisiana, Whites, # # 7 6.# # Age-adjusted to the U.S. standard population. Data source for the U.S. was the 18 SEER registries. * Incidence rate of regions/louisiana is significantly different from that of the U.S.

9 Rate per 1, Liver and Intrahepatic Bile Duct Cancer Incidence 1, by Region: Louisiana, Blacks, # Age-adjusted to the U.S. standard population. Data source for the U.S. was the 18 SEER registries. * Incidence rate of regions/louisiana is significantly different from that of the U.S.

10 Liver and Intrahepatic Bile Duct Cancer: Trends of Incidence Rates 1,, Whites, Rate per 1, LA Male LA Female U.S.Male U.S.Female Year of Diagnosis 1 Age-adjusted to the U.S. standard population. U.S. data source: 18 SEER registries.

11 Liver and Intrahepatic Bile Duct Cancer: Trend of Incidence Rates 1,,Blacks Rate per 1, LA Male LA Female U.S.Male U.S.Female Age-adjusted to the U.S. standard population. U.S. data source: 18 SEER registries. Year of Diagnosis

12 Liver and Intrahepatic Bile Duct Cancer: Mortality Rates 1 Louisiana vs. U.S., 9-13 Rate Per 1, %* U.S. Louisiana %* 17%* White Male White Female Black Male Black Female %* 1 Age-adjusted to the U.S. standard population. Mortality data source was the National Center of Health Statistics (NCHS). * Mortality rate of Louisiana is significantly different from that of the U.S.

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14 Liver and Intrahepatic Bile Duct Cancer: Trends of Mortality Rates 1,,Whites, Rate per 1, U.S. Male U.S. Female LA Male LA Female Year of Death 1 Age-adjusted to the U.S. standard population. Data source: National Center of Health Statistics (NCHS).

15 Liver and Intrahepatic Bile Duct Cancer: Trends of Mortality Rates 1,, Blacks, Rate per 1, U.S. Male U.S. Female LA Male LA Female Year of Death 1 Age-adjusted to the U.S. standard population. Data source: National Center of Health Statistics (NCHS).

16 Liver and Intrahepatic Bile Duct: Trends of Incidence and Mortality Rates by Race, Louisiana, Rate per 1, White Mortality (APC :.*) Black Mortality (APC:.7*) White Incidence (APC: 3.4*) Black Incidence (APC: 5.1*) Year of Diagnosis/Death *APCs were calculated using weighted least squares method

17 Liver and Intrahepatic Bile Duct: Trends of Incidence and Mortality Rates by Gender, Louisiana, Rate per 1, Male Mortality (APC :.3*) Female Mortality (APC: 1.6*) Male Incidence (APC: 4.1*) Female Incidence (APC:.7*) Year of Diagnosis/Death *APCs were calculated using weighted least squares method

18 Liver and Intrahepatic Bile Duct Cancer 1 : Louisiana 5-Year Relative Survival by Stage, White Males, year Relative Survival Rate (%) 3% 5% % 15% 1% 5% % localized Regional Distant Distant 19% Regional 7% Percent of Cases by Stage Unstaged* 6% localized 48% 1 Liver and intrahepatic bile duct cancer includes first primary only (sequence number or 1). The stage distribution is based on Summary Stage. * The survival rate for unstaged cases could not be calculated.

19 Liver and Intrahepatic Bile Duct Cancer 1 : Louisiana 5-Year Relative Survival by Stage, Black Males, year Relative Survival Rate (%) 3% 5% % 15% 1% 5% Distant % Regional 9% Percent of Cases by Stage Unstaged 7% localized 44% % localized Distant Unstaged 1 Liver and intrahepatic bile duct cancer includes first primary only (sequence number or 1). The stage distribution is based on Summary Stage. * The survival rate for cases diagnosed at a regional stage could not be calculated.

20 Liver and Intrahepatic Bile Duct Cancer 1 : Louisiana 5-Year Relative Survival by Stage, White Females, % Percent of Cases by Stage 5-year Relative Survival Rate (%) % 15% 1% 5% 1.% 13.% 3.1% Distant % Regional 19% Unstaged 9% localized 5% % localized Regional Distant Unstaged 1 Liver and intrahepatic bile duct cancer includes first primary only (sequence number or 1). The stage distribution is based on Summary Stage. * The survival for unstaged cases not be calculated.

21 5-year Relative Survival Rate (%) Liver and Intrahepatic Bile Duct Cancer 1 : Louisiana 5-Year Relative Survival by Stage, Black Females, % % 15% 1% 5% %.3%.%.% Regional 31% Distant 18% Percent of Cases by Stage Unstaged % localized 51% localized Regional Distant Unstaged 1 Liver and intrahepatic bile duct cancer includes first primary only (sequence number or 1). The stage distribution is based on Summary Stage. * The survival rate for unstaged cases could not be displayed due to fewer than 16 cases.

22 Data Sources Surveillance, Epidemiology, and End Results (SEER) Program ( SEER*Stat Databases, National Cancer Institute, DCCPS, Surveillance Research Program, Surveillance Systems Branch, released April 16, based on the November 15 submission. For Incidence: Incidence - SEER 18 Regs Research Data + Hurricane Katrina Impacted Louisiana Cases, Nov 15 Sub (-13) <Katrina/Rita Population Adjustment> SEER*DMS - LTR , June 7, 16 For Mortality: Mortality all COD, aggregated with States, Total U.S. ( ) <Katrina/Rita Population Adjustment> For Survival: Incidence - SEER 18 Regs Research Data + Hurricane Katrina Impacted Louisiana Cases, Nov 15 Sub ( varying)

23 Acknowledgements Hospital cancer registries ( Louisiana Cancer Registrars Association ( Physicians and staff members in: Medical records offices Pathology laboratories Physician offices and clinics Hospice programs and nursing homes Regional and central offices of the Louisiana Tumor Registry ( School of Public Health, LSU Health Sciences Center New Orleans Louisiana Cancer and Lung Trust Fund Board Coroners offices

24 Sources of LTR Funding National Cancer Institute, SEER Program National Program of Cancer Registries, CDC Louisiana Health Care Services Division

25 Editors Xiangrong Li, MD, MSPH Meichin Hsieh, PhD, MSPH, CTR Lauren Maniscalco, MPH Xiaocheng Wu, MD, MPH, CTR Contributors Brent Mumphrey, BS Tina Lefante, MPH Lisa Pareti, BS, RHIT, CTR Yong Yi, PhD, MS

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