Alireza Rafiei, DVM, PH.D

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1 Dept. Immunology, Sari Medical School, Mazandaran University of Medical Sciences, Sari, Iran, P.O.Box: Phone: Fax : Mail: rafiei@mazums.ac.ir rafiei1710@gmail.com Alireza Rafiei, DVM, PH.D Personnel Information Current academic position First name: Alireza Last name: Rafiei Nationality: Iranian Place of Birth: Mobarakeh, Esfahan, Iran Marital status: Married Professor of Immunology Director of Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences Founder and Editor in chief of Research in Molecular Medicine (RMM) Education 1-Doctor of Veterinary Medicine (DVM) faculty of veterinary medicine, Tehran University, Tehran 2- Ph.D. Medical Immunology Faculty of Medicine, Tehran University of Medical Sciences, Tehran, 3- Research Fellowship for DNA Vaccine Hamamatsu Medical University (Japan), Faculty of Medicine, Laboratory of Immunology and Biology,

2 Major administrative Responsibilities present Editor in chief of Research in Molecular Medicine (RMM) present Professor of Immunology, Department of Immunology, Molecular and Cell Biology Research Center, Department of Immunology, Faculty of Medicine, Mazandaran University of Medical Sciences Associated Professor Department of Microbiology and Immunology, Faculty of medicine, Mazandaran University of Medical Sciences Vice Chancellor for Education and Research, Faculty of medicine,, Mazandaran University of Medical Sciences Vice Chancellor for Research, Faculty of medicine,, Mazandaran University of Medical Sciences Member of Research board, Mazandaran University of Medical Sciences Fonder and director of Molecular and Cell Biology Research Center (MCBRC), Mazandaran University of Medical Sciences, Sari, Iran Assistant professor Department of Microbiology and Immunology, Faculty of medicine, Mazandaran University of Medical Sciences Award for Excellence in Researching (Mazandaran University of Medical Sciences ) Award and Honors Award for Excellence in teaching (Mazandaran University of Medical Sciences ) Award for Excellence in teaching (Mazandaran University of Medical Sciences ) Received a letter of appreciation from Ministry of Health, Treatment and Medical Education, Dr Kamran Bagheri Lankarani Award for Excellence in Researching (Mazandaran University of Medical Sciences )

3 Journal Publication Ramazani M, Asnaashari M, Ahmadi R, Zarenejad N, Rafiei A, Yazadani Charati J. The Effect of Final Rinse Agitation with Ultrasonic or Diode laser on Coronal Microleakage of Root-Canal Treated Teeth. Iranian Endodontic Journal 2018;13(1): Ghanbarimasir Z, Bekhradnia A, Morteza-Semnani K, Rafiei A, Razzaghi-Asl N, Kardan M. Design, synthesis, biological assessment and molecular docking studies of new 2-aminoimidazolequinoxaline hybrids as potential anticancer agents. Spectrochim Acta A Mol Biomol Spectrosc Dec 29;194: doi: /j.saa Rafiei A, Mohammadjafari H, Ahifar A, Alipour A, Mirabi AM. The urinary and serum levels of IL- 32 in children with febrile urinary tract infections. Future Sci OA Sep 14;3(4):FSO242. doi: /fsoa Abedi SM, Mohammadjafari H, Rafiei A, Bazi S, Yazdani P. Urinary matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 biomarkers for predicting renal scar in children with urinary tract infection. Turk J Urol Dec;43(4): Hosseini SH, Rafiei A, Gaemian A, Tirgari A, Zakavi A, Yazdani J, Bolhari J, Golzari M, Esmaeili Douki Z, Vaezzadeh N. Comparison of the Effects of Religious Cognitive Behavioral Therapy (RCBT), Cognitive Behavioral Therapy (CBT), and Sertraline on Depression and Anxiety in Patients after Coronary Artery Bypass Graft Surgery: Study Protocol for a Randomized Controlled Trial. Iran J Psychiatry Jul;12(3): Bagheri-Nesami M, Rezai MS, Ahangarkani F, Rafiei A, Nikkhah A, Eslami G, Shafahi K, Hajalibeig A, Khajavi R. Multidrug and co-resistance patterns of non-fermenting Gram-negative bacilli involved in ventilator-associated pneumonia carrying class 1 integron in the North of Iran. Germs Sep 1;7(3): doi: /germs PMID: Morsaljahan Z, Rafiei A, Valadan R, Abedini M, Pakseresht M, Khajavi R. Association between interleukin-32 polymorphism and multiple sclerosis. J Neurol Sci Aug 15;379: doi: /j.jns Zare Z, Tehrani M, Rafiei A, Valadan R, Mohammadi M. Differential expression of glutamate transporters in cerebral cortex of paraoxon-treated rats. Neurotoxicol Teratol Jul;62: doi: /j.ntt PMID: Naghavi-Alhosseini M, Tehrani M, Ajami A, Rafiei A, Taghvaei T, Vahedi-Larijani L, Hossein-Nataj H, Asgarian-Omran H. Tim-3 Up-regulation in Patients with Gastric Cancer and Peptic Ulcer Disease. Asian Pac J Cancer Prev Mar 1;18(3): PMID: Sabbaghian E, Roodbari F, Amani J, Rafiei A. In vitro evaluation of a polytope DNA construct as a novel DNA vaccine strategy against human cytomegalovirus-associated diseases. Acta Virol. 2017;61(1): doi: /av_2017_01_97. PMID: Shafia S, Vafaei AA, Samaei SA, Bandegi AR, Rafiei A, Valadan R, Hosseini-Khah Z, Mohammadkhani R, Rashidy-Pour A. Effects of moderate treadmill exercise and fluoxetine on behavioural and cognitive deficits, hypothalamic-pituitary-adrenal axis dysfunction and alternations in hippocampal BDNF and mrna expression of apoptosis - related proteins in a rat

4 model of post-traumatic stress disorder. Neurobiol Learn Mem Mar;139: doi: /j.nlm PMID: Amjadi O, Rafiei A, Haghshenas M, Navaei RA, Valadan R, Hosseini-Khah Z, Omran AH, Arabi M, Shakib RJ, Mousavi T, Ashrafi GH. A systematic review and meta-analysis of seroprevalence of varicella zoster virus: A nationwide population-based study. J Clin Virol Feb;87: doi: /j.jcv PMID: Alizadeh-Navaei R, Rafiei A, Abedian-Kenari S, Asgarian-Omran H, Valadan R, Hedayatizadeh- Omran A. Comparison of leucine-rich repeat-containing G protein-coupled receptor 5 expression in different cancer and normal cell lines. Biomed Rep Jul;5(1): Bagheri-Nesami M, Rafiei A, Eslami G, Ahangarkani F, Rezai MS, Nikkhah A, Hajalibeig A. Assessment of extended-spectrum β-lactamases and integrons among Enterobacteriaceae in device-associated infections: multicenter study in north of Iran. Antimicrob Resist Infect Control Dec 1;5:52. ecollection PMID: Farhadi R, Rafiei A, Hamdamian S, Zamani H, Yazdani J. Pentraxin 3 in neonates with and without diagnosis of pulmonary hypertension. Clin Biochem Mar;50(4-5): doi: /j.clinbiochem PMID: Mesali H, Ajami A, Hussein-Nattaj H, Rafiei A, Rajabian Z, Asgarian-Omran H, Hosseini V, Taghvaei T, Tehrani M. Regulatory T Cells and Myeloid-Derived Suppressor Cells in Patients with Peptic Ulcer and Gastric Cancer. Iran J Immunol Sep;13(3): doi: IJIv13i3A2. PMID: Fakhraei F, Haghshenas MR, Hosseini V, Rafiei A, Naghshvar F, Alizadeh-Navaei R. Detection of human papillomavirus DNA in gastric carcinoma specimens in a high-risk region of Iran. Biomed Rep Sep;5(3): Epub 2016 Jul 29. Rafiei A, Ajami A, Mirabi AM, Saffar MJ, Amjadi O, Haghshenas MR, Abedian F, Khaje-Enayati P. Serum Levels of Soluble CD26, A Novel Prognostic Marker for Hepatitis E Infection. Jundishapur J Microbiol February; 9(2): e Alizadeh-Navaei R, Rafiei A, Abedian-Kenari S, Asgarian-Omran H, Valadan R, Hedayatizadeh- Omran A. Effect of First Line Gastric Cancer Chemotherapy Regime on the AGS Cell Line - MTT Assay Results. Asian Pac J Cancer Prev. 2016;17(1): Yazdannejat H, Hosseinimehr SJ, Ghasemi A, Pourfallah TA, Rafiei A. Losartan sensitizes selectively prostate cancer cell to ionizing radiation. Cell Mol Biol (Noisy-le-grand) Jan 11;62(1):30-3. PMID: Amjadi O, Mousavi T, Rafiei A, Afzali M A, Yousefpour M, Ghaemi A. Therapeutic and Nutritional Effects of Pomegranate from the Perspective of Islamic Texts, Traditional and Modern Medicine. J Mazandaran Univ Med Sci. 2016; 25 (134) : Ghaemi A, Fakheri H, Rafiei A, hosseini V, Homayounfar R, Amiri Z, et al. Interaction between C677T and A1298C MTHFR Gene Polymorphisms and Weight Loss Diet in Treatment of NAFLD. J Mazandaran Univ Med Sci. 2016; 25 (133) :10-24 Karkhane M, Marzban A, Rafiei A, Akhtari J. Cancer Stem Cells: Cell Heterogeneity in Cancer and Nanotechnology Approaches for Their Treatment. J Mazandaran Univ Med Sci. 2016; 25 (133) :

5 Abedini M, Paksersht M, Rafiei A, Valadan R, Amjadi O, Khajavi R, et al. Demographic and Clinical Characteristics of Multiple Sclerosis. J Mazandaran Univ Med Sci. 2016; 25 (132) :13-22 Eslami G, Rezaie M S, Salehifar E, Rafiei A, Langaie T, Rafati M R et al. Epidemiology of Extended Spectrum Beta Lactamases Producing E. coli Genes in Strains Isolated from Children with Urinary Tract Infection in North of Iran. J Mazandaran Univ Med Sci. 2016; 25 (132) : Mousavi T, Rafiei A, Amjadi O, Yoosefpour M, Zakavi A. Medicinal and Nutritional Properties of Grapes in Islamic References, Traditional, and Modern Medicine. J Mazandaran Univ Med Sci. 2015; 25 (130) : Esmaelizad M Jafari S Rafiei A. Absolute quantification of murine interleukine-4, interleukine- 10 and interferon-γ gene transcripts using Real Time PCR. Archives of Razi Institute. 2015; 70 (2): Kheradmand M, Enayati A, Rafiei A, Moosazadeh M. Population Based Cohort Studies in Iran: A Review Article. J Mazandaran Univ Med Sci. 2015; 25 (125) : Moradian F, Farziyan M A, Rafiei A R. Anticancer Effect of Bovine Lactoferrin on Human Esophagus Cancer Cell Line. Res Mol Med. 2016; 4 (1) :18-23 Zarenejad N, Asgary S, Ramazani N, Haghshenas MR, Rafiei A, Ramazani M. Coronal microleakage of three different dental biomaterials as intra-orifice barrier during nonvital bleaching. Dent Res J (Isfahan) Nov-Dec;12(6): PMID: Shadman M, Rajabian Z, Ajami A, Hussein-Nattaj H, Rafiei A, Hosseini V, Taghvaei T, Abbasi A, Tehrani M. Frequency of γδ T Cells and Invariant Natural Killer T Cells in Helicobacter Pyloriinfected Patients with Peptic Ulcer and Gastric Cancer. Iran J Allergy Asthma Immunol Oct;14(5): Valadan R, Hedayatizadeh-Omran A, Alhosseini-Abyazani MN, Amjadi O, Rafiei A, Tehrani M, Alizadeh-Navaei R. Data supporting the design and evaluation of a universal primer pair for pseudogene-free amplification of HPRT1 in real-time PCR. Data Brief Jul 6;4: doi: /j.dib ecollection 2015 Sep. PMID: Hedayatizadeh-Omran A, Valadan R, Rafiei A, Tehrani M, Alizadeh-Navaei R. VERO stable cell lines expressing full-length human epidermal growth factor receptors 2 and 3: platforms for subtractive phage display. DNA Cell Biol Sep;34(9): doi: /dna Epub 2015 Jun 29. PMID: Rezai MS, Salehifar E, Rafiei A, Langaee T, Rafati M, Shafahi K, Eslami G. Characterization of Multidrug Resistant Extended-Spectrum Beta-Lactamase-Producing Escherichia coli among Uropathogens of Pediatrics in North of Iran. Biomed Res Int. 2015;2015: doi: /2015/ Epub 2015 May 3. PMID: Rafiei A, Mohammadjafari H, Bazi S, Mirabi AM. Urinary neutrophil gelatinase-associated lipocalin (NGAL) might be an independent marker for anticipating scar formation in children with acute pyelonephritis. J Renal Inj Prev Jun 1;4(2): doi: /jrip ecollection PMID: Hedayatizadeh-Omran A, Rafiei A, Alizadeh-Navaei R, Tehrani M, Valadan R, Moradzadeh K, Panbechi M, Taghavi SM. Role of HER2 in brain metastasis of breast cancer: a systematic review and meta-analysis. Asian Pac J Cancer Prev. 2015;16(4): PMID: Farzaneh Fakhraei, Mohammad Reza Haghshenas, Vahid Hosseini, Alireza Rafiei, Farshad Naghshvar and Reza Alizadeh-Navaei. Detection of HPV DNA in Gastric carcinoma specimens

6 from the Mazandaran, northern Iran during International Journal of Genomics, 2015 in press. Amjadi O, Rafiei A, Ajami A, Valadan R, Janbaabaei G. Blood groups: In Health and Diseases. Res Mol Med. 2015; 3 (4) :1-9 Khalatbary A, Mohammadnegad B, Ghaffari E, Rafiei A. Oleuropein Attenuates Deltamethrininduced Apoptosis in Rat Cerebellar Purkinje Neurons. Res Mol Med. 2015; 3 (4) : Valadan R, Rafiei A, Hashemitabr G, Bassami MR, Protein A-Specific Enrichment of Insertcontaining Phage in Antibody Phage Display Library. J Mazandaran Univ Med Sci 2015; 24(120): Amjadi O, Abedini M, Rafiei A, Safaii S, Ajami A, Hosseinian A. Interferons in Autoimmune Diseases: Friend or Foe. J Mazandaran Univ Med Sci. 2015; 24 (121) : Pakseresht M, Shobeyri S, Rafiei A, Amjadi O, Abedini M. The Role of Infectious Agents on Pathogenesis of Multiple Sclerosis. J Mazandaran Univ Med Sci. 2015; 24 (122) :0-0 Hedayatizadeh-Omran A, Valadan R, Rafiei A, Ajami A, Tehrani M, Alizadeh-Navaei R. Generation of CHO Stable Cell Line Overexpressing HER2: an In Vitro Model for Breast Cancer. Res Mol Med. 2015; 3 (3) :6-10 Brzezinski P, Chiriac A, Keng Hoong C, Rafiei A, Babbi L, Al-Qattan MM, Giangaspero M, Millet C, Duprez J-P. Dermatology Eponyms sign Lexicon (O). Our Dermatol Online. 2015;6(1): Amiri F, Moradian F, Rafiei A. Anticancer effect of lactoferrin on Gastric Cancer Cell Line AGS. Res Mol Med. 2015; 3 (2) :11-16 Valadan R, Rafiei A, Gholamreza Hashemi Tabar G, Bassami MR, Endogenous expression of EGFR and ErbB2 mrna and protein in some commonly used laboratory cell lines. Protein Expression and Purification. Under review. Mohammadjafari H, Rafiei A, Kosaryan M, Yeganeh Y, Hosseinimehr SJ. Determination of the severity of ureteropelvic junction obstruction using urinary epidermal growth factor and kidney injury molecule 1 levels. Biomark Med. 2014;8(10): Sabbaghian E, Roodbari F, Rafiei A, Amani J. In Silico Design of a Multimeric Polytope as a Highly Immunogenic DNA Vaccine Against Human Cytomegalovirus. Journal of Applied Biotechnology Reports, 2014; 1 (4): Akhtari J, Ebrahimnejad P, Rafiei A. A Review on the Use of Nanoparticles in the Release of Growth Factors. J Mazandaran Univ Med Sci. 2015; 24 (122) : Mousavi T, Rafiei A, Yoosefpour M, Nutritional Value and Health Benefits of Dates According to Islamic Recourses and Traditional Medicine. J Mazandaran Univ Med Sci 2014; 24(117): (Persian). Mousavi T, Haghshenas MR, Rafiei A, Navaei RA, Khah ZH. Hepatitis B Virus Genotypes Distribution with HBsAg Positive in the North of Iran (Mazandaran) During Med Arch Dec;68(6): Alizadeh-Navaei R, Rafiei A, Hedayatizadeh-Omran A, Mohammadzadeh I, Arabi M. Gene susceptibility in Iranian asthmatic patients: a narrative review. Ann Med Health Sci Res Nov;4(6):

7 Houshmand B, Amjadi O, Rafiei A, Rouzegar M, Abrishami M, Talebi Ardakani M. The potential of human-derived periodontal ligament stem cells to osteogenic differentiation: An In vitro investigation. Res Mol Med. 2014; 2 (4) : Mohammadjafari H, Rafiei A, Mousavi SA, Alaee A, Yeganeh Y. Role of urinary levels of endothelin-1, monocyte chemotactic Peptide-1, and N-acetyl glucosaminidase in predicting the severity of obstruction in hydronephrotic neonates. Korean J Urol Oct; 55 (10): Mousavi T, Rafiei A, Yoosefpour M. Nutritional Value and Health Benefits of Dates According to Islamic Recourses and Traditional Medicine. J Mazandaran Univ Med Sci. 2014; 24 (117): Iradj Maleki, Mahmood Reza Aminafshari, Tarang Taghvaei, Vahid Hosseini, Alireza Rafiei, Zhila Torabizadeh, Maryam Barzin, Elahe Orang. Serum immunoglobulin A concentration is a reliable biomarker for liver fibrosis in non-alcoholic fatty liver disease. World J Gastroenterology, 2014; Sep 21;20(35): Ahanjan M, Kholdi S, Rafiei A. Antibiotic-resistance Patterns and Frequency of TEM and CTX Type Extended-spectrum β-lactamases in Acinetobacter Clinical Isolates. J Mazandaran Univ Med Sci. 2014; 24 (116) : Amjadi O, Rafiei A, Yousofpoor M. Remedial astonishments of fig in the holy Quran and medicine. Religion and Health. 2014; 2 (1) :10-10 Hosseini khah Z, Bahadori Z, Rafiei A, Hajilooi M. Association of FCγRIIA (CD32) polymorphism with susceptibility to brucellosis. Res Mol Med. 2014; 2 (3) : Mohammadjafari H, Rafiei A, Abedi M, Aalaee A, Abedi E. The role of urinary TIMP1 and MMP9 levels in predicting vesicoureteral reflux in neonates with antenatal hydronephrosis. Pediatr Nephrol. 2014: 29(5): Amjadi O, Rafiei A, Ajami A, Hosseini V, Asgarian-Omran H. Inflammation, a key factor in cancer ambush. Res Mol Med. 2014; 2 (2):1-15. Ahmad Daryani; Mehdi Sharif; Hamed Kalani; Alireza Rafiei; Farzad Kalani; Ehsan Ahmadpour Electrophoretic Patterns of Toxoplasma gondii Excreted/Secreted Antigens and Their Role in Induction of the Humoral Immune Response. Jundishapur J Microbiol April; 7(4): e9525. Maleki I, Rastgar A, Hosseini V, Taghvaei T, Rafiei A, Barzin M, Torabizadeh Z, Naghshvar F, Khalilian A. High sensitive CRP and pentraxine 3 as noninvasive biomarkers of nonalcoholic fatty liver disease. Eur Rev Med Pharmacol Sci Jun;18(11): Mojtaba Shadman, Abolghasem Ajami, Alireza Rafiei, Hadi Hussein-Nattaj, Vahid Hosseini, Tarang Taghvaei, Hamideh Mesali, Mohsen Tehrani. Phenotypic evaluation of natural killer (NK) and natural killer T (NKT)-like cells in patients with peptic ulcer and gastric cancer caused by Helicobacter pylori infection. J Mazand Univ Med Sci 2014; 23(110): (Persian). Fatemeh Moradian, Ramisa Sharbafi, Alireza Rafiei. Lactoferrin, Isolation,Purification and Antimicrobial Effects. Journal of Medical and Bioengineering, 2014: 3 (3): Rafiei A, Amjadi O, Babamahmoodi F. Leptospirosis or Rice Field Fever: A review on the Pathogenesis. 2014; 2 (1) :23-39 Rafiei A, Amjadi O, Ghavibonieh Kh. Mystery of the Holy Quran and narratives emphasize the consumption of olive. J Rel Health. 2013; 1 (1): Hosseinzadeh-Colagar H, Amjadi O, Valadan R, Rafiei A. Minimal HER1 and HER2 expressions in CHO and HEK-293 cells cause them appropriate negative cells for HERs-related studies. Res Mol Med. 2013; 1: (3): 6-16.

8 Rafiei A, Hosseini V, Janbabai G, Ghorbani A, Ajami A, Farzmandfar T, Azizi MD, Gilbreath JJ, Merrell DS. Polymorphism in the interleukin-17a promoter contributes to gastric cancer. World J Gastroenterol Sep 14;19 (34): PMID: Alireza Ghaemi, Fourugh Azam Taleban, Azita Hekmatdoost, Alireza Rafiei, Vahid Hosseini, Zohreh Amiri, Reza Homayounfar, Hafez Fakheri. How Much Weight Loss is Effective on Nonalcoholic Fatty Liver Disease? Hepat Mon December; 13(12): e Ghaemi AR, Taleban FA, Hekmatdoost A, Rafiei AR, Hosseini V, Amiri Z, Homayounfar R, Fakheri H. Effect of weight reduction diet on non-alcoholic fatty liver disease. Iranian Journal of Nutrition Sciences & Food Technology. 2013; 8 (2): MohamadJafari H, Rafiei A, Abedi M, Aalaee A, Mirabi AM, Abedi E. Urinary neutrophilgelatinase associated lipocalin is a more prognostic biomarker to distinguish antenatal hydronephrosis in neonates. Res Mol Med (RMM). 2013; 1 (2): Farazmandfar T, Rafiei A, Hashemi-Sotehoh MB, Valadan R, Alavi SM, Moradian F. A simplified protocol for producing Taq DNA polymerase in biology laboratory. Res Mol Med (RMM). 2013; 1 (2): Rafiei A, Gilbreath JJ, Merrell DS. Response to Abadi and Kusters, World J Gastroenterol 19: World J Gastroenterol Jun 21;19 (23): PMID: Rafiei A, Darzyani AM, Taheri S, Haghshenas MR, Hosseinian A, Makhlough A. Genetic diversity of HCV among various high risk populations (IDAs, thalassemia, hemophilia, HD patients) in Iran. Asian Pac J Trop Med Jul;6(7): PMID: Valadan R, Rafiei A, Tehrani M, Nejatollahi F. Resistance to HER2-targeted therapy. Res Mol Med (RMM). 2013; 1 (1):1-9. Mottaghi-Dastjerdi N, Soltany-Rezaee-Rad M, Ajami A, Rafiei A, Abediankenari S, Gharaee E, Hashemi Sooteh M, Rahbarizadeh F. Production of Cyclin D1 specific sirnas by double strand processing for gene therapy of ESCC. Res Mol Med (RMM). 2013; 1 (1) : Ajami A, Shadman M, Rafiei A, Hosseini V, TalebiBezmin Abadi A, Alizadeh A, Hosseini-khah Z. Prevalence of EPIYA motifs in Helicobacter pylori strains isolated from patients with gastroduodenal disorders in northern Iran. Res Mol Med (RMM). 2013; 1 (1) : Rafiei A, Hosseini SH, Taheri M, Hosseni-khah Z, Hajilooi M, Mazaheri Z. Influence of IL-1RN intron 2 variable number of tandem repeats (VNTR) polymorphism on bipolar disorder. Neuropsychobiology. 2013; 67(2): doi: / , PMID: Rafiei A, Amjadi O. Personalized medicine; a bridge between current medicine and the future healthcare. J Clin Exc 2013; 1(2): (Persian). Abolghasem Ajami, Mojtaba Shadman, Alireza Rafiei, Vahid Hosseini, Amin Talebi- BezminAbadi, Ahad Alizadeh, Zahra Hosseini-khah. Prevalence of EPIYA motifs in Helicobacter pylori strains isolated from patients with dyspeptic disorders in northern Iran. Res Mol Med, 2013; 1 (1): Haghshenas M, Golini-Moghaddam T, Rafiei A, Emadeian O, Shykhpour A, Ashrafi GH. Prevalence and type distribution of high-risk human papillomavirus in patients with cervical cancer: a population-based study. Infect Agent Cancer Jun 6;8(1):20. PMID: Hosseinimehr SJ, Mahmoudzadeh A, Rafiei A. Arginine increases genotoxicity induced by methyl methanesulfonate in human lymphocytes. Cytotechnology. 2013; 65 (3): doi: /s x. PMID: [PubMed]

9 Safar MJ, Khalilian AR, Rafee AR, Parsaei MR, Imanikhani S, Shojaei J, Saffar H. Bordetella Pertussis IgG and IgA Antibodies Seroprevalence Among 1-35 y-old Population: The Role of Subclinical Pertussis Infection. Indian J Pediatr Mar;79(3): Houshmand B, Rafiei A, Hajilooi M. Influence of cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms in periodontitis. Arch Oral Biol. 2012;57(9): doi: /j.archoralbio PMID: Mohammad Reza Haghshenas, Farhang Babamahmoodi, Alireza Rafiei, Vahid Vahedi, Reza Alizadeh-Navaei, Prevalence of Hepatitis C virus genotypes in the Northern of iran (Mazandaran) from 2009 to Health Med, 2012, Houshmand B, Hajilooi M, Rafiei A, Bidgoli M, Soheilifar S. Evaluation of IL-8 gene polymorphisms in patients with periodontitis in Hamedan, Iran. Dent Res J (Isfahan). 2012; 9 (4): PMID: Mohammadi Gorji S, Karimpor Malekshah AA, Hashemi-Soteh MB, Rafiei A, Parivar K, Aghdami N. Effect of mesenchymal stem cells on Doxorubicin-induced fibrosis. Cell J. 2012;14(2): PMID: Rafiei A, Hedayati Zadeh omran A, Babamahmoodi F, Alizqadeh Navaee R, Valadan R. Review of Leptospirosis in Iran. J Mazandaran Univ Med Sci. 2012; 22 (94) : Nadi E, Hajilooi M, Babakhani D, Rafiei A. Platelet endothelial cell adhesion molecule-1 polymorphism in patients with bronchial asthma. Iran J Allergy Asthma Immunol. 2012; 11(4): PMID: Rafiei A, Abedini M, Hosseini SH, Hosseini-Khah Z, Bazrafshan B, Tehrani M. Toll Like Receptor-4 896A/G Gene Variation, a Risk Factor for Migraine Headaches. Iran J Immunol Sep;9(3): PMID: Fakhar M, Mirzaei M, Rafiei A, Armat S, Mojtahedian M. Comparative Evaluation of Hydatid Cyst Fluid and Fetal Bovine Serum (FBS) in Culture Medium of Rat Fibroblast Cells. J Mazandaran Univ Med Sci. 2012; 21 (86) : Rafiei A, Hosseini V, Janbabai G, Fazli B, Ajami A, Hosseini-Khah Z, Gilbreath J, Merrell DS. Inducible nitric oxide synthetase genotype and Helicobacter pylori infection affect gastric cancer risk. World J Gastroenterol. 2012; 18(35): PMID: Rafiei A, Khajavi R, Haghshenas M, Hosseini-khah Z, Farazmandfar T, Sharbafi R. Association between Interleukin-28B Genetic Variants and Hepatitis C. J Mazandaran Univ Med Sci. 2012; 22 (95): Hosseinian Amiri A, Rafiei A. Alkaptonuria in a middle-aged female. Caspian J Intern Med Fall;3 (4): PMID: Ghorbani A, Hosseini V, Ajami A, Rafiei A, Hosseini-khah Z, Janbabai G. Association between polymorphism of interleukin 17 (IL-17F) and increased susceptibility to gastric cancer. J Mazandaran Univ Med Sci. 2012; 22 (91) : Moslemizade N, Rafiei A, Yazdani F, Yusefnezhad K, The effect of magnesium sulfate on bleeding time and nitric oxide production in preeclamsia. Pak J Biol Sci. 2011; 14(2): Hassannia H, Abediankenari S, Ghaffari J, Rafiei A, Yazdani J, Jeivad F et al. Association between T Cell Immunoglobulin and Mucin Domain-1 Gene Polymorphisms with Allergic Rhinitis. J Mazandaran Univ Med Sci. 2011; 21 (85) :2-8 Heidari, M., Malekshah, A.K., Parivar, K., Khanbabaei, R., Rafiei, A. Effect of fibroblast co-culture on in vitro maturation and fertilization of mouse preantral follicles International Journal of Fertility and Sterility, 2011; 5 (1), pp. 1-8.

10 Talebi Bezmin Abadi A, Rafiei A, Ajami A, Hosseini V, Taghvaei T, Jones KR, Merrell DS. Helicobacter pylori homb, but not caga, is associated with gastric cancer in Iran. J Clin Microbiol Sep;49 (9): doi: /JCM Epub 2011 Jul 6. PMID: Ghaffari J, Rafiei A.R, Ajami A, Mahdavi M, Hoshiar B. Serum interleukins 6 and 8 in mild and severe asthmatic patients, is it difference? Caspian Journal of Internal Medicine, 2011; 2 (2), pp Hosseinian A, Pakravan N, Rafiei A, Feyzbakhsh SM. Aluminum phosphide poisoning known as rice tablet: A common toxicity in North Iran. Indian J Med Sci Apr;65(4): doi: / PMID: Ghorbanalipoor, S., Ajami, A., Rafiei, A., Taghvaei, T., Hosseini, V., Paylakhi, S.H. Expression of interleukin 11 (IL-11) in benign and malignant lesions of the gastric mucosa Journal of Mazandaran University of Medical Sciences,2011; 21 (84), pp Rafiei, A., Haghshenas, M.R., Azizi, M.D., Taheri, S., Babamahmoudi, F., Makhlough, A., Hoseini, S.H. Risk factors for Hepatitis C virus among high-risk populations (Intravenous drug addicts and patients with Thalassemia, Hemophilia, hemodialysis) in Mazandaran, Journal of Mazandaran University of Medical Sciences, 2011; 20 (81), pp Haghshenas M, Babamahmoodi F, Rafiei A, Vahedi V. The Correlation between HCV Genotypes and Liver Damage in HCV Patients. J Mazandaran Univ Med Sci. 2011; 21 (85) : Amiri, A.H., Rafiei, A. Analysis of patients with post-chemotherapy Arthralgia and Arthritis in breast cancer, Indian Journal of Medical Sciences, 2010; 64 (5), pp Sharbafi R, Moradian F, Rafiei A, Barzegar A. Isolation and Purification of Bovine Lactoferrin. J Mazandaran Univ Med Sci. 2011; 21 (84) : Ghaffari J, Khademloo M, Saffar MJ, Rafiei A, Masiha F. Hypersensitivity to house dust mite and cockroach is the most common allergy in north of Iran. Iran J Immunol. 2010; 7(4): doi: IJIv7i4A5. PMID: Hedayatizadeh-Omran A, Rafiei A, Hajilooi M, Haghshenas M. Interferon-gamma low producer genotype over presented in patients with focal brucellosis. Pak J Biol Sci Nov 1;13 (21): PMID: Ajami A, Rafiei A, Naghshvar F, Sedghei M, Elisay A, Hedayatizadeh-Omran A. Association of human leukocyte antigen and esophageal cancer in North of Iran. Pak J Biol Sci Dec 15;12(24): PubMed PMID: Hedayatizadeh-Omran A, Rafiei A, Hajilooi M, Haghshenas M. Interferon-gamma low producer genotype over presented in patients with focal brucellosis. Pak J Biol Sci Nov 1;13 (21): Daryani A, Sharif M, Meigouni M, Mahmoudi FB, Rafiei A, Gholami Sh, Khalilian A, Gohardehi Sh, Mirabi AM. Prevalence of intestinal parasites and profile of CD4+ counts in HIV+/AIDS people in north of Iran, Pak J Biol Sci Sep 15;12(18): PubMed PMID: Amiri AH, Tarrahi MJ, Rafiei A. Clinical finding and outcome in suicidal attempt due to intravenous injection of kerosene. Pak J Biol Sci Mar 1;12(5): PubMed PMID: Houshmand B, Rafiei A, Hajilooi M, Mani-Kashani K, Gholami L. E-selectin and L-selectin polymorphisms in patients with periodontitis. J Periodontal Res Feb;44(1): Epub 2008 Oct 7. PubMed PMID:

11 Haidari M, Hajilooi M, Rafiei AR, Rezaii AA, Hoseinipanah SM. E-selectin genetic variation as a susceptibility factor for ischemic stroke. Cerebrovasc Dis. 2009;28(1): Epub 2009 May 6. PubMed PMID: Rezaii AA, Hoseinipanah SM, Hajilooi M, Rafiei AR, Shikh N, Haidari M. Interleukin-1 receptor antagonist gene polymorphism and susceptibility to ischemic stroke. Immunol Invest. 2009;38(3-4): PubMed PMID: Talebi Bezminabadi A, Mohabati Mobarez A, Ajami A, Rafiei A, Taghvaei T. Evaluation on antibiotic resistance of H. pylori isolated from patients admitted to Tooba Medical Center, Sari. J. Mazandaran University of Medical Sciences, 2009 June-July; 19(70): Rafiei AR, Hasanjani Roushan MR, Hoseini Khah Z, Ajami A, Orouji Z. Comparison of Serum Levels of Soluble CD26 and CD30 in Patients with Brucellosis and Controls. J Babol Univ Med Sci; 2009 Jun- Jul; 11(2): Reza JS, Alireza R, Mostafa A, Alireza K, Mehrdad H. Association of tumor necrosis factoralpha-308 (G-->A) polymorphism and susceptibility to brucellosis. J Microbiol Immunol Infect Feb;42(1):22-6. PubMed PMID: Rafiei A, Ajami A, Hajilooi M, Etemadi A. Th-1/Th-2 cytokine pattern in human amoebic colitis. Pak J Biol Sci Oct 15;12(20): PubMed PMID: Aoshi T, Nagata T, Suzuki M, Uchijima M, Hashimoto D, Rafiei A, Suda T, Chida K, Koide Y. Identification of an HLA-A*0201-restricted T-cell epitope on the MPT51 protein, a major secreted protein derived from Mycobacterium tuberculosis, by MPT51 overlapping peptide screening. Infect Immun Apr;76(4): Epub 2008 Jan 22. PubMed PMID: ; Hooshmand B, Hajilooi M, Rafiei A, Mani-Kashani KH, Ghasemi R. Interleukin-4 (C-590T) and interferon-gamma (G5644A) gene polymorphisms in patients with periodontitis. J Periodontal Res Feb;43(1): PubMed PMID: Rafiee AR, Makhlough A, Hashemi Nasab S, Hosseinian Amiri A, Abedian F. The Th1 and Th2 cytokine profile in patients with chronic kidney disease. J Mazand Univ Med Sci 2008; 18(63):37-45 Rafiei A, Makhlough A. Hashemi Nasab S, Mahdavi MR, Mirabi AM. Comparison of serum levels of CD26 and CD30 in chronic renal failure and hemodialytic patients, Journal of Babol University of Medical Sciences, 2008; 10(1): Hedayati MT., Hajhaydari Z., Bromand S., Shokohi T., Rafiei A, MohammadpourRA. A study on specific IgE against Candida albicans in atopic dermatitis patients referred to Boali Hospital, Sari- Iran. J. Mazandaran University of Medical Sciences 2007 Oct, Nov; 17(60): Rafiei A, Hajilooi M, Vahedi M, Shakib RJ. The Ser128Arg polymorphism for E-selectin gene and brucellosis. Infect Genet Evol Jul;7(4): Epub 2007 Mar 1. PubMed PMID: Rafiei A., Hosseini khah Z., Ghasemian R., Agami A., Rowshan R. Association of FC RIIA polymorphism with brucellosis. Journal of Mazandaran University of Medical Sciences. 2007; 55: Rafiee A, Hoseini Khah Z, Ajami A, Ghasemian R, Hasanjani Roshan M, Soltani H, et al. Association between FCγ RIIA polymorphism and brucellosis. J Mazandaran Univ Med Sci. 2007; 16 (56) :21-28 Ajami A, Rafiei A. Cytokine production in Hymenolepis nana infection. Iran J Immunol Dec;4(4): PubMed PMID:

12 Nadi E, Hajilooi M, Zeraati F, Ansari M, Tavana S, Hashemi SH, Rafiei A. E-selectin S128R polymorphism leads to severe asthma. Iran J Allergy Asthma Immunol Jun;6(2): PubMed PMID: Hedayati M, Hajhaydari Z, Bromand S, Shokohi T, Rafiei A, Mohamadpour R. A Study on Specific IgE Against Candida Albicans in Atopic Dermatitis Patients Referred to Boali Hospital, Sari- Iran. J Mazandaran Univ Med Sci. 2007; 17 (60) : Rafiei A, Hajilooi M, Shakib RJ, Alavi SA. Transforming growth factor-beta1 polymorphisms in patients with brucellosis: an association between codon 10 and 25 polymorphisms and brucellosis. Clin Microbiol Infect Jan;13(1): PubMed PMID: Rafiei A, Ardestani SK, Kariminia A, Keyhani A, Mohraz M, Amirkhani A. Dominant Th1 cytokine production in early onset of human brucellosis followed by switching towards Th2 along prolongation of disease. J Infect Nov;53(5): Epub 2006 Feb 20. PubMed PMID: Mazaheri S, Hajilooi M, Rafiei A. The G-308A promoter variant of the tumor necrosis factor-alpha gene is associated with migraine without aura. J Neurol Dec;253(12): Epub 2006 Oct 24. PubMed PMID: Hajilooi M, Rafiei A, Reza Zadeh M, Tajik N. Association of interleukin-1 receptor antagonist gene polymorphism and susceptibility to human brucellosis. Tissue Antigens Oct;68 (4): PubMed PMID: Rafiei A, Hajiloee M. Association between Phe206Leu allele polymorphism of L-selectin gene and coronary artery disease. J Mazandaran Univ Med Sci. 2006; 16 (52) : Rezazadeh M, Hajilooi M, Rafiei A, Haidari M, Nikoopour E, Kerammat F, Mamani M, Ranjbar M, Hashemi H. TLR4 polymorphism in Iranian patients with brucellosis. J Infect Sep;53(3): Epub 2005 Dec 15. PubMed PMID: Sharif M, Gholami Sh, Ziaei H, Daryani A, Laktarashi B, Ziapour SP, Rafiei A, Vahedi M. Seroprevalence of Toxoplasma gondii in cattle, sheep and goats slaughtered for food in Mazandaran province, Iran, during Vet J Sep;174(2): Epub 2006 Aug 21. PubMed PMID: Rafiei A., Hajilooi M. Association between Phe206Leu allele polymorphism of L-selectin gene and coronary artery disease. Journal of Mazandaran University of Medical Sciences. 2006; 16 (52): Rafiei A, Hajilooi M, Shakib RJ, Shams S, Sheikh N. Association between the Phe206Leu polymorphism of L-selectin and brucellosis. J Med Microbiol May;55(Pt 5): PubMed PMID: Haidari M, Hajilooi M, Rezazadeh M, Rafiei A, Alavi SA, Keramat F. Polymorphism in the promoter region of the CD14 gene and susceptibility to Brucellosis. Immunol Invest. 2006; 35(2) : PubMed PMID: Rezazadeh M, Hajilooi M, Haidari M, Rafiei A, Alavi SA, Keramat F. Association of susceptibility to brucellosis and interleukin-4 promoter polymorphism. Scand J Infect Dis. 2006;38(11-12): PubMed PMID: Rafiei A., Kariminia A. Evaluation of cellular immunity of patients with brucellosis by measuring interferon gamma (IFN- ) and Interleukine-13 (IL-13) by flow cytometry and ELISA. J Medical faculty Guilan University of Medical Sciences, 2005; 14(55): Rafiei A., Karimina A., Mohraz M., Evaluation of cell proliferation and interferon gamma (IFN- ) expression in patients with brucellosis. J Hamadan University of Medical Sciences. 2005; 12 (1):

13 Rafiei A. Karimina A. Ajami A. Diminished IFN- production but increased IL-12 production in chronic human brucellosis. Journal of Mazandaran University of Medical Sciences. 2004; 14 (42): Rafiei A, Kariminia A, Ajami A, Kabodalyan ardestani S. Reduction in production of IFN-γ is accompanied with an increase in production of IL-12 in chronic brucellosis patients. J Mazandaran Univ Med Sci. 2004; 14 (42) : Rafiei A. Keyhani A., Kariminia A., Ajami A. Detection of intracellular cytokine expression in human brucellosis. The journal of faculty of medicine, Tehran University of Medical Sciences, 2004; 62 (5). Nasiri E., Noori M. Rafiei A. Amizargar A. Effect of obstructive cholestasis on gonadotropin and germ cell apoptosis in the adult male rat. Yakhteh (The cell), 2003; 5(18): Rafiei A. Prions (review). Journal of Iranian veterinary association, vol. 3, no 5, 2001

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