P powered by. Patient Experience

Transcription

1 P powered by Patient Experience

2 P : game changer in improving cancer patient outcomes Digital Personalised Medicine Solutions...the use of anonymised, real-time improving patient experience & Patient Reported Outcome data to outcomes, uniquely combined with improve clinical outcomes # 1 2 Smart apps which have demonstrated to improve the patient physician relationship Advanced data-analytics to large-scale data providing real world evidence into the effectiveness of treatments

3 disrupting cancer care with patient-driven, real time impact patient experience clinical outcomes hospital efficiency

4 NUTS & BOLTS

5 treating patients as individuals patient better informed & more at ease personalised treatment information all personal information in 1 place tools improving patient experience

6 empowering patients & informing clinicians improves patient-doctor dialogue track & share data on well-being better insight in to situation advanced privacy & security

7 real-time insights for clinicians

8 EVIDENCE & TRIALS

9 research supporting impact OWise Pitkethly M et al. (2008) Recordings or summaries of consultations for people with cancer. Cochrane Database of Systematic Reviews. Issue 3. Art. No.: CD Scott JT et al. (2003) Recordings or summaries of consultations for people with cancer. Cochrane Database of Systematic Reviews. Issue 2. Art. No.: CD Brandes K, et al. (2015) The characteristics and effectiveness of Question Prompt List interventions in oncology: a systematic review of the literature. Psycho-Oncology. Vol 24(3): Greene J & Hibbard JH (2012) Why Does Patient Activation Matter? An Examination of the Relationships Between Patient Activation and Health-Related Outcomes. J Gen Intern Med 27: 520 Basch E et al. (2017) Overall Survival Results of a Trial Assessing Patient-Reported Outcomes for Symptom Monitoring During Routine Cancer Treatment. JAMA. June 4, 2017 Basch E et al. (2016) Symptom Monitoring with Patient-Reported Outcomes During Routine Cancer Treatment: A Randomized Controlled Trial. Journal of Clinical Oncology. Vol 34: 6 Barbera et al. (2015) Does routine symptom screening with ESAS decrease ED visits in breast cancer patients undergoing adjuvant chemotherapy? Support Care Cancer. Vol 23: 3025

10 US study: patient lives extended by 5 months when using electronic PRO-system Cancer patients receiving the electronic PRO solution were 100% 90% Rela=ve improvements by using e-proms 2,3 less frequently admitted to the ER or hospitalised 2 80% 70% 60% 50% remained on chemotherapy longer (~ 2 months) 3 40% 30% 20% 10% Living longer (~5 months) 3 0% Healh related Quality of Life Less likely to worsen Less likely to be addmi7ed to ER Overall survival Less likely to be hospitalised 2. Basch et al Journal of Medical Oncology: Symptom Monitoring With Patient-Reported Outcomes During Routine Cancer Treatment: A Randomized Controlled Trial 3. Basch E et al JAMA: Overall Survival Results of a Trial Assessing Patient-Reported Outcomes for Symptom Monitoring During Routine Cancer Treatment

11 Direct impact OWise é survival é quality of life ê A&E visits é information recall é patient satisfaction ê anxiety é patient activation

12 independently validated & published in peer-reviewed medical journal JMIR CANCER Original Paper Young-Afat et al JMIR Cancer 2016 Patients and Health Care Providers Opinions on a Supportive Health App During Breast Cancer Treatment: A Qualitative Evaluation JMIR CANCER Young-Afat et al Conclusions: This evaluation of a supportive health app shows positive experiences among patients and their medical teams. Based on experiences in this study, patients may need to be actively encouraged to regularly register symptoms within health apps to generate sufficient patient-reported app data for use in clinical practice and scientific research. (JMIR Cancer 2016;2(1):e8) doi: /cancer.5334 KEYWORDS breast cancer; health apps; quality of life; patient-reported outcomes; PROs Results: A total of 15 patients aged years participated. The medical team consisted of 7 physicians and 3 specialized breast cancer nurses. Out of the 15 patients, 12 (80%) used the app to obtain information on breast cancer and treatment. A total of 11 out of 12 patients (92%) evaluated this information as useful. All 15 patients used the app to record consultations with practitioners, and 14 (93%) found this useful. Symptom registration was used by 8 out of 15 patients (53%), and was found useful by 4 out of these 8 patients (50%). Overall, 14 out of 15 patients (93%) would recommend the app to other patients. The app, in particular the recording function, was rated as useful by 9 out of 10 medical professionals (90%), and they reported that it did not increase consultation time. These 9 professionals would recommend the app to their patients.

13 results from independent pilot study on OWise Young-Afat et al JMIR-Cancer

14 valued by patients & doctors every day 90% 90% I can now explain much better to my doctors how I have been feeling in between hospital visits, Yve, 41 years For almost one year I have used OWise and tracked by well being intensively for that time. I can say from the bottom of my heart that it has been a tremendous support for me, Jolijn, 56 years The OWise patient appears to deal with her emotional issues much earlier in the process, breast cancer surgeon, UMC Utrecht

15 Tech firms working to extend cancer survival rates by up to five months Published: 16:15

16 NOVEMBER 2017 The Growing Value of Digital Health Evidence and Impact on Human Health and the Healthcare System Top 25 Apps CONDITION MANAGEMENT TOP FREE AND PUBLICLY AVAILABLE 318, , ,169 98,456 66, Cancer Asthma Diabetes CONDITION MANAGEM OWise Breast Cancer by Px HealthCare B.V. Helps individuals regain control during chaotic times of illness and treatment AsthmaMD by Mobile Breeze Asthma management application. Asthma diary and visualize asthma activity on a color graph. mysugr by mysugr GmbH PRESCRIPTION FILLING AND C Auto-logs data via connected devices for blood glucose and activity tracking. Gamification of blood sugar control

17 no cost for patient no cost for clinician

18 Cancer Treatment Helpline

19 patients at the centre & in control Share my data OWise implementation in NHS Lothian: 1) smart alerts for medical support 2) real time PRO-data incorporated in EPR Share my data Edinburgh Cancer Centre New hospital Wednesday or clinic 1 November 2017 Alert: You are experiencing a lot of pain, please contact the CTH Note: With Dr. Jon McGregor Data access key Stop data sharing A C D 4 E Share my data Cancer Treatment Helpline

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21 As a breast cancer patient, the OWise App is an invaluable tool to give peace of mind to the patient, that during stressful treatment periods, monitoring is thorough and continuous. It is easy to use with clear guidance. Julie, OWise User As a team the OWISE group are very collaborative working with stakeholders across the cancer journey trying to identify ways to maximise the impact of PROs. Their interest in feedback and ongoing assessment of research into PROs should ensure that the system continues to develop and improve in the future. Lucy, Medical Oncologist, ECC I think the app is brilliant. I can record everything so when I go to chemo every 3 weeks and they ask how I've been, I have precise record of side effects & when they happened during the cycle. Sheila, OWise User

22 impact on clinical outcomes, patient wellbeing & hospital efficiency Two clinical trials

23 two clinical trials underway NHS Lothian, inves0ga0ng the integrated version of OWise and comparing the effects to a previously studied pa0ent cohort EQ5D Toxici0es Hospital Resources The Royal Marsden Hospital, North West London Hospitals, Ins0tute of Cancer Research & Imperial College Health Partners comparing the impact in two popula0ons (with and without OWise) PAM EQ5D Medical resource use

24 ADVANCED DATA ANALYTICS

25 P : applying advanced data-analytics to improve outcomes Insights from large-scale Patient-Reported-Outcome data real-time patient health data identifying correlations & trends patient subgroups improved treatment efficacy & safety patient population data treatment efficacy & treatment effects improved health safety drug-drug interactions disease prognosis outcomes

26 examples of initial insights from OWise chemotherapy data in the Netherlands & UK Chemotherapy NL Chemotherapy UK AC CAF AC CAF CMF CAF FEC EC FEC EC EC

27 PRO-insights from NL/UK Chemo PRO Anthracyclines PRO CMF 90% 80% 70% 60% 50% 40% 30% 20% 10% Sleep quality Fa7gue Physical effort Appe7te Sore mouth (ulcers) Sickness Low mood FEC Skin rash AC Stool (watery/mushy) Weight loss 0% Reported Nega7ve Trends

28 breast cancer in development: OWise 2.0 benefitting all cancer patients 2.0 for all cancers

29 Thank You!

30 P Patient Experience O ptimising O ncology O utcomes anne@pxhealthcare.com