Prostate-Specific Antigen (PSA) Test

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1 Prostate-Specific Antigen (PSA) Test Early Detection of Prostate Cancer Who should get tested? If you are a man over the age of 50, it s recommended that you speak with your doctor about your risk of developing prostate cancer and whether you should have a PSA test. Your healthcare provider may recommend a PSA test if you: men in Canada will be diagnosed with prostate cancer in their lifetime. The third leading cause of cancer death, when prostate cancer is detected early, it s more likely to be successfully treated. What is PSA and how is it connected to prostate cancer? Prostate-specific antigen (PSA) is a protein produced within the prostate gland. PSA is mostly found in semen, but small amounts can also be found in the blood of healthy men. PSA levels depend on age and naturally go up as you age. There are many reasons why PSA levels fluctuate and higher levels may indicate the presence of prostate cancer or other prostate conditions. Prostate cancer is typically a slow growing cancer that can be present for many years before causing symptoms. Prostate cancer is highly treatable if diagnosed in the early stages and a PSA test can be valuable in aiding early detection. are almost 50 years old have a family history of prostate cancer are of African ancestry have symptoms of prostate cancer have already been diagnosed with prostate cancer and are being monitored When is this test ordered? A PSA test may be ordered by your healthcare provider to: help detect prostate cancer early even if you don t have any signs or symptoms check for cancer if you are experiencing signs or symptoms of prostate cancer confirm a diagnosis when other tests suggest prostate cancer predict a prognosis (outcome) for prostate cancer predict if cancer has spread outside the prostate plan treatment for prostate cancer monitor you if you are already being treated for prostate cancer determine if cancer treatments are working determine if cancer has come back after treatment What is a prostate-specific antigen (PSA) test? A prostate-specific antigen (PSA) test is a simple blood test that measures the amount of PSA protein in your blood. Measuring PSA levels can be an useful tool in diagnosing prostate cancer as well as monitoring the progress of the disease in someone who has already been diagnosed with prostate cancer.

2 How can I get tested? Testing is completed by LifeLabs at a Patient Service Centre or via our mobile lab service (available in select cities) through a simple blood sample. You will require a completed test requisition from your healthcare provider. Understanding your results Test results will be provided directly to your healthcare provider for discussion with you. The report will indicate: 1. Total PSA level in the blood 2. Free PSA level 3. Ranges for PSA levels PSA levels depend on your age. As you get older, your PSA level will naturally go up. If you have a high PSA level, your doctor will talk to you about your options. A higher than normal PSA level doesn t always mean you have prostate cancer. High PSA levels can also indicate: an enlarged prostate due to benign prostatic hyperplasia an inflamed or infected prostate (called prostatitis) a urinary tract infection How is the test performed? Blood sample How much does it cost? The price of this test varies by province. The test may be covered by your private insurance or provincial health plan under some circumstances. Talk to your doctor about your options. When will I get my results? Results are available to your healthcare provider within 2 weeks. Sources Statistics Canada: Prostate cancer trends in Canada, 1995 to 2012 Prostate Cancer Canada Canadian Cancer Society It s important for you to discuss your PSA level results with your doctor. Your doctor will help you determine your risk of prostate cancer in relation to your age, family history and other personal information.

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4 Laboratory Requisition This requisition form, when completed, constitutes a referral to LifeLabs laboratory physicians. It is for the use of authorized health care providers only. COMPLETE and ACCURATE information is required in all shaded areas. THIS AREA IS FOR LAB USE Patient Surname (from CareCard) First Initial(s) Date of Birth Sex Bill to: MSP ICBC WorkSafeBC Patient Other DAY MONTH YEAR Chart Number F Room # (LTC use only) M PHN I.D. Number Patient Address City, Province Postal Code Patient Telephone Number Ordering Physician, Address, MSP Practitioner Number Locum for: C0 Number Date/Time of Collection Phlebotomist Data Entry Physician Date/Time/Name of Medication Copy to: Address, MSP Practitioner Number MSC # Pregnant Fasting Phone Fax Yes No hours prior to test Diagnosis and indications for guideline protocol and special tests Telephone Requisition Received By: INITIAL/DATE For tests indicated with a shaded tick box, consult provincial guidelines and protocols ( HEMATOLOGY LABEL ALL SPECIMENS WITH MICROBIOLOGY URINE TESTS PATIENT S FIRST AND LAST NAME, DOB AND/OR PHN & SITE Urine culture - list current antibiotics: PT-INR On Warfarin? ROUTINE CULTURE HFE Hemochromatosis (check ONE box only) List current antibiotics: Macroscopic microscopic if dipstick positive Throat Sputum Blood Macroscopic urine culture if pyuria or nitrite present Sibling/parent is C282Y/C282Y homozygote (DNA testing) Macroscopic (dipstick) Microscopic Wound Site: Special case (if ordered together) CHEMISTRY Deep Glucose - fasting (see reverse for patient instructions) Wound Site: HEPATITIS SEROLOGY GTT - gestational diabetes screen (50 g load, 1 hour post-load) One box only. For other Hepatitis Markers, please order GTT hour test) Other: under Other Tests section. Hemoglobin A1c VAGINITIS Albumin/creatinine ratio (ACR) - Urine Hepatitis A (anti-hav lgm) Initial (smear for BV & yeast only) LIPIDS Hepatitis B (HBsAg, plus anti-hbc if required) Chronic/recurrent (smear, culture, trichomonas) Hepatitis C (anti-hcv) One box only. For other lipid investigations, please Trichomonas testing order under Other Tests section and provide diagnosis. Hepatitis B (HBsAg, anti-hbc, anti-hbs) Baseline cardiovascular risk assessment or follow-up GROUP B STREP SCREEN (Pregnancy only) Hepatitis C (anti-hcv) Total, HDL, non-hdl & LDL Cholesterol, Triglycerides, fasting) Vagino-anorectal swab Penicillin allergy Investigation of hepatitis immune status Follow-up of treated hypercholesterolemia (Total, HDL & Hepatitis A (anti-hav, total) non-hdl Cholesterol, fasting not required) CHLAMYDIA (CT) & GONORRHEA (GC) Hepatitis B (anti-hbs) Follow-up of treated hypercholesterolemia (ApoB only, CT & GC Testing Hepatitis marker(s) HBsAg fasting not required) Source/site: Urethra Cervix Urine GC culture: Throat Rectal HIV SEROLOGY Other: THYROID FUNCTION One box only. For other thyroid investigations, please order under Other Tests section and provide diagnosis. Monitor thyroid replacement therapy (TSH Only) Suspected Hypothyroidism OTHER CHEMISTRY TESTS Sodium Creatinine/eGFR Potassium Calcium Albumin Creatine kinase (CK) Alk phos PSA - Known or suspected prostate ALT cancer (MSP billable) Bilirubin PSA screening (self-pay) GGT Pregnancy Test T. Protein Serum Urine The personal information collected on this form and any medical data subsequently developed will be used and disclosed only as permitted or required by the Personal Information Protection Act (and related acts and regulations) of British Columbia. LifeLabs privacy policy is available at Use of this form implies consent for the use of STOOL SPECIMENS History of bloody stools? Yes Stool culture Stool ova & parasite exam Stool ova & parasite (high risk, 2 samples) DERMATOPHYTES Dermatophyte culture KOH prep (direct exam) Specimen: Skin Nail Hair Site: MYCOLOGY Yeast Fungus Site: Date Requisition is valid for one year from the date of issue. HIV Serology (patient has legal right to choose not to have their name and address reported to public health non-nominal reporting) Non-nominal reporting ECG OTHER TESTS Fecal Occult Blood (Age asymptomatic q2y) Copy to Colon Screening Program. Fecal Occult Blood (other indications) Standing Order requests - expiry and frequency must be indicated Physician Signature D2400 (01/18)

5 LifeLabs Locations Hours of operation are subject to change. For current hours and locations visit our website at You will be asked to present your Care Card/BC Services Card at each visit. For tests not covered by MSP, payment can be made by VISA, MasterCard and Debit. Test Results for clinicians: Patients can register to receive test results at Patient Service Centres Hours (Monday to Friday) Fax Kamloops - St. Paul St. Paul Street 8:00 to 4:00 (250) Kamloops - Nicola Nicola Street 8:00 to 3:00 (250) Kamloops - Tranquille Tranquille Road 7:00 to 4:00; (Sat. 7:00 to 12:00) (250) Kamloops - Harrison 1966 Harrison Way 8:00 to 4:00 (250) Prince George Victoria Street 7:00 to 4:00; (Sat. 7:00 to 12:00) (250) Quesnel Front Street 7:30 to 3:00 (250) Terrace Park Avenue 8:00 to 4:00 (250) Dawson Creek rd Avenue 7:30 to 3:00 (250) Nelson 806 Vernon Street 8:00 to 4:00 (250) Kimberley 260-4th Avenue 7:30 to 3:30 (250) Scotch Creek Squilax-Anglemont Road 9:00 to 1:00 (Wed and Fri only) PATIENT INSTRUCTIONS: (unless otherwise indicated by your physician) Fasting Required: Do not eat or drink (except water) for 8-12 hours before the following tests: GLUCOSE - fasting GTT-gestational diabetes confirmation and GTT - non pregnant LIPIDS/CHOLESTEROL - if indicated Note: Chewing gum and brushing teeth during the fasting period is acceptable. Fasting is preferred, but not required for the following tests: Homocysteine, Iron/Transferrin H. Pylori: Do not eat, drink (except water), or smoke for 4 hours before the test. Do not drink any fluid for the last hour of fasting. AM Cortisol and Testosterone: Collect sample within 3 hours of waking Patient Instructions are also available on our website APPOINTMENTS ARE REQUIRED FOR THE FOLLOWING TESTS: Call to schedule an appointment Mon - Fri from 9am - 5pm or Toll Free Ambulatory Blood Pressure DOT/non-DOT Drug Screen Holter Monitor Lactose Tolerance/Hydrogen Breath Test Paternity / DNA Semen Analysis APPOINTMENTS ARE AVAILABLE BUT NOT REQUIRED FOR THE FOLLOWING TESTS: Legal Drug Screen Panorama Pre-Natal Screening Test For tests not listed above, you may arrive without an appointment OR schedule an appointment at a LifeLabs location online at D2400 (01/18)