DAFTAR PUSTAKA. Onkologi Kebidanan dan Kandungan FKUI/RSCM; 1992.

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1 DAFTAR PUSTAKA 1. American Cancer Society. Cancer Facts and Figures 2011, ( diakses 6 Juni, (2015). 2. Aziz MF. Current management and trend of ovarian cancer. In Saifudddin AB, Affandi B and Winknjosastro GH. Womens Health. The proceeding of the Xvth. Asian and Ocenia Congress of Obstetrics and Gynecology. Jakarta : Yayasan Bina Pustaka. S. Prawihardjo, 1995.p Nuranna L. Tumor ganas ovarium tipe epitel. Jakaarta : Sub Bagian Onkologi Kebidanan dan Kandungan FKUI/RSCM; Tumor markers for Ovarian Cancer ( section=cancer_types), diakses 6 Juni (2015). 5. Kanda S, Oka Y. Structure, Synthesis, and Phylogenyof Kisspeptin and its Receptor, Kauffman AS, Smith JT,In: Kisspeptin Signaling in Reproductive Biology,Advances in Experimental Medicine and Biology. Springer Science Business Media, LLC; 2013; p Sonigo C, Binart N. Overview of the impact of Kisspeptin on reproductive function. Annales d Endocrinologie 2012;73: Dova, Golfinopoulos V, Pentheroudakis G, et al. Systemic Dissemination in Cancer of Unknown Primaryis Independent of Mutational Inactivation of the KiSS1Metastasis-suppressor Gene. Pathol Oncol Res 2008;14: Cunningham FG, Gant NF, Leveno KJ, Gilstrap LC, Hauth JC, Wenstrom KD. Obstetri Williams Edisi ke-21 Vol. 2. Jakarta : ECG; p. 934, Kotani M Detheux M, Vandebogaerde A, Communi D, Vanderwinden JM, Le Poul E, Brezilien S, Tyldesley R, Suarez-Huerta N, Vandeput F, et al. (2001) The metastasi suppressor gene KiSS1 encodes Kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem 276: Jemal A, Murray T, Samuels A et al. Cancer statistics, CA Cancer J Clin 2003; 53:

2 11. Saifuddin, Abdul Bari, dkk Ilmu Kebidanan Sarwono Prawirohardjo. Jakarta : PT Bina Pustaka Sarwono Prawirohardjo. 12. Prabhu VV, Sakhtivel KM, Guruvayoorappan C. Kisspeptin (KiSS1): essential player in supressing tumor metastasis. Asian Pac J Cancer Prev, 14 (11), Smith JT, Clifton DK, Steiner RA (2006). Regulation of the neuroendocrine reproductive axis by Kisspeptin-GPR54 signaling. Reproduction, 131, Muir AI, Chamberlain L, Elshourbagy NA, Michalovich D, Moore DJ, Calamari A, Szekeres PG, Sarau HM, Chambers JK, Murdock P, et al. (2001) AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS1. J Biol Chem 276: Ohtaki T, Shintani Y, Honda S, Matsumoto H, Hori A, Kanehashi K, Terao Y, Kumano S, Takatsu Y, Masuda Y, et al. (2001) Metastasis suppressor gene KiSS1 encodes peptide ligand of a G-proteincoupled receptor. Nature 411: Welch DR, Chen P, Miele ME, McGary CT, Bower JM, Stanbridge EJ, and Weissman BE (1994) Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity. Oncogene 9: Mechaly AS, Vinas J, Murphy C, Reith M & Piferrer. Gene structure of the KiSS1 receptor-2 in the atlantic halibut: insights into the evolution and regulation of KiSS1r genes. Mol Cel Endocrin 2010; 317: Hata K, Dhar DK, Watanabe Y, et al (2007). Expression of metastin and a G-protein-coupled receptor (AXOR12) in epithelial ovarian cancer. Eur J Cancer, 43, Stafford LJ, Xia C, Ma W, Cai Y, Liu M (2002). Identification and characterization of mouse metastasis-suppressor KiSS1 and its G- protein coupled receptor. Cancer Res, 62, Weipei Z, Aihua G, Xin C, Feng L, Jiang N & Hong Z. Expression of KiSS1 in epithelial ovarian cancer and its role in metastasis. Applied Mech & Mat 2012; 140: Gupta GP and Massagué J (2006) Cancer metastasis: building a framework. Cell 127: Sastrawinata, Sulaiman. dkk Ilmu Kesehatan Reproduksi: Obstetri Patologi.Edisi 2. Jakarta: EGC hal :

3 23. DeChemey AH, Pernoll ML. Current Obstetric and Gynecologic Diagnosis and Treatment 8th edition. Norwalk : Appleton & Lange; p Helm, CW. Ovarian Cyst. 19 maret (Available at : accessed on 15 Juni 2013) 25. Moeloek FA, Nuranna L, Wibowo N, Purbadi S. Standar Pelayanan Medik Obstetri dan Ginekologi. Jakarta : Perkumpulan Obstetri dan Ginekologi Indonesia; p Ovarian Cyst. 6 April (Available at accessed on 15 Juni 2013) 26. Steeg PS. Metastasis suppressors alter the signal transduction of cancer cells. Nat Rev Cancer 2003; 3: Welch DR, Hunter KW. A new member of the growing family of metastasis suppressors identified in prostate cancer. J Natl Cancer Inst 2003; 95: Bari R, Zhang YH, Zhang F, et al (2009). Transmembrane interactions are needed for KAI1/CD82-mediated suppression of cancer invasion and metastasis. Am J Pathol, 174, Prabhu VV, Siddikuzzaman, Grace VM, Guruvayoorappan C (2012). Targeting tumor metastasis by regulating Nm23 gene expression. Asian Pac J Cancer Prev, 13, Welch, D. R. (1996) J. Natl. Cancer Inst. 88, Lee, J. H., Miele, M. E., Hicks, D. J., Phillips, K. K., Trent, J. M., Weissman, B. E., and Welch, D. R. (1996). KiSS1, a novel human malignant melanoma metastasis-suppressor gene. J Natl Cancer Inst 88, Lee, J. H., and Welch, D. R. (1997). Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS1. Cancer Res 57, Xavier d Anglemont de Tassigny and William Henry Colledge (2010). The Role of Kisspeptin Signaling in Reproduction. PHYSIOLOGY; 25: Bilban M, Ghaffari-Tabrizi N, Hintermann E, et al (2004). Kisspeptin- 10, a KiSS1/metasin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblast. J Cell Sci, 117,

4 35. Tena-Sempere M, Felip A, Gómez A, Zanuy S, Carrillo M (2012). Comparative insights of the Kisspeptin/Kisspeptin receptor system: lessons from non-mammalian vertebrates. Gen Comp Endocrinol, 175, Cho, S. G., Yi, Z., Pang, X., Yi, T., Wang, Y., Luo, J., Wu, Z., Li, D., and Liu, M. (2009b). Kisspeptin-10, a KISS1-derived decapeptide, inhibits tumor angiogenesis by suppressing Sp1-mediated VEGF expression and FAK/Rho GTPase activation. Cancer Res 69, Navenot JM, Fujii N & Peiper SC. KiSS1 metastasis supressor gene product induces suppression of tyrosine kinase receptor signaling to Akt, tumor necrosis factor family ligand expression, and apoptosis. 38. Becker JA, Mirjolet JF, Bernard J, Burgeon E, Simons MJ, Vassart G, Parmentier M, and Libert F (2005) Activation of GPR54 promotes cell cycle arrest and apoptosis of human tumor cells through a specific transcriptional program not shared by other Gq-coupled receptors.biochem Biophys Res Commun 326: Hori A, Honda S, Asada M, Ohtaki T, Oda K, Watanabe T, Shintani Y, Yamada T, Suenaga M, Kitada C, et al. (2001) Metastin suppresses the motility and growth of CHO cells transfected with its receptor. Biochem Biophys Res Commun 286: Gao GL, Liu LD, Zou XS, et al. Expression of KiSS1, matrix metalloproteinase-9, nuclear factor-kappabp65 in ovarian tumour. Zhonghua Fu Chan Ke Za Zhi. (2007)42(1): Takino T, Koshikawa N, Miyamori H, et al. Cleavage of metastasis suppressor gene product KiSS1 protein/metastin by matrix metalloproteinases. Oncogene (2003), 22(30): Makri A, Pissimissis N, Lembessis P,et al. The Kisspeptin (KiSS1)/GPR54 system in cancer biology.cancer Treat Rev. (2008);34(8): Nagai K, Doi R, Katagiri F, et al. Prognostic value of metastin expression in human pancreatic cancer.j Exp Clin Cancer Res. (2009) ;21; Schmid K, Wang X, Haitel A,et al.kiss1 overexpression as an independent prognostic marker in hepatocellular carcinoma: an immunohistochemical study. Virchows Arch.( 2007); 450 (2) : Oakley AE, Clifton DK, Steiner RA (2009). Kisspeptin signaling in the brain. Endocr Rev, 30,

5 46. Martin TA, Watkins G, Jiang WG (2005). KiSS1 expression in human breast cancer. Clin Exp Metastas, 22, Liang S, Yang ZL (2007). Expression of KiSS1 mrna in pancreatic ductal adenocarcinoma and non-cancerous pancreatic tissues in SD rats. Zhong Nan Da Xue Xue Bao Yi Xue Ban, 32, Dhar DK, Naora H, Kubota H, et al (2004). Downregulation of KiSS1 expression is responsible for tumor invasion and worse prognosis in gastriccarcinoma. Int J Cancer, 10, Babwah AV, Pampillo M, Min L, et al (2012). Single-cell analyses reveal that KiSS1-R-expressing cells undergo sustained Kisspeptininduced signaling that is dependent upon an influx of extracellular Ca +. Endocrinol, 153, Sanchez-Carbayo M, Capodieci P, Cordon-Cardo C (2003). Tumor suppressor role of KiSS1 in bladder cancer: loss of KiSS1 expression is associated with bladder cancer progression and clinical outcome. Am J Pathol, 162, Goldberg SF, Miele ME, Hatta N, et al (2003). Melanoma metastasis suppression by chromosome 6: evidence for a pathway regulated by CRSP3 and TXNIP. Cancer Res, 63: Nash KT, Welch DR (2006). The KiSS1 metastasis suppressor: mechanistic insights and clinical utility. Front Biosci, 1; Mitchell DC, Abdelrahim M, Weng J, Stafford LJ, Safe S, Bar-Eli M, Liu M (2006). Regulation of KiSS1 metastasis suppressor gene expression in breast cancer cells by direct interaction of transcription factors activator protein-2alpha and specificity protein-1. Journal Biology Chemistry; 281: Ying J, Berk M, Singh LS, Tan H, Yin L, Powell CT, et al. KiSS1 supresses metastasis in human ovarian cancer via inhibition of protein kinase C alpha. Clin Exp Metastasis 2005; 22: Harms JF, Welch DR, Miele ME. KISS1 metastasis suppression and emergent pathways. Clin Exp Metast 2003; 20: Jiang Y, Berk M, Singh LS, et al. KiSS1 suppresses metastasis in human ovarian cancer via inhibition of protein kinase C alpha. Clin Exp Metast 2005;22: Zhang SL, Yu Y, Jiang T, Lin B, Gao H: Expression and significance of KiSS1 and its receptor GPR54 mrna in epithelial ovarian cancer. Zhonghua Fu Chan Ke Za Zhi 2005, 40:

6 58. Prentice LM, Klausen C, Kalloger S, Kobel M, McKineey S, Santos JL, et al. Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma. BMC Medicine 2007; 5: Krajewski SJ, Burke MC, Anderson MJ, McMullen NT, Rance NE (2010). Forebrain projections of arcuate neurokinin B neurons demonstrated by anterograde tracttracingand monosodium glutamate lesions in the rat. Neuroscience; 166(2): Makri A, Pissimissis N, Lembessis P, Poluchronakos C, Koutsillieris M. The Kisspeptin (KiSS1)/GPR54 system in cancer biology. Cancer Treatment Reviews (2008) 34, Simerly RB (2002) Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrain. Annu Rev Neurosci 25: Matsui H, Takatsu Y, Kumano S, Matsumoto H, Ohtaki T (2004) Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat. Biochem Biophys Res Commun 320: Panidis D, Rousso D, Koliakos G, et al. Plasma metastin levels are negatively correlated with insulin resistance and free androgens in women with polycystic ovary syndrome. Fertil Steril 2006;85: Montes AF, Gomez JG, Viejo MN, Bermejo MA, Urrutia SA & Mata JG. Epidemiology and etiology of ovarian cancer. Interchopen,

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