BASF Canola oil: Convenient Healthy Food for Your Heart and Brain. Andy Beadle UK Parliamentary Food and Health Forum 16th March 2010
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1 e BASF Canola oil: Convenient Healthy Food for Your Heart and Brain Andy Beadle UK Parliamentary Food and Health Forum 16th March 2010
2 Plant biotechnology at BASF BASF Plant Science Plant Science Sweden DNA LandMarks CropDesign Metanomics SunGene Ames, IA Limburgerhof Raleigh, NC Facts & Figures Verbund of innovative technologies 8 sites in 5 countries founded in 1998 R&D Units External Cooperations Global R&D network ~ 700 employees in R&D 40 cooperations worldwide Expenditures Billion Source: BPS
3 Introduction: Not all fats are bad BASF Plant Scienc Fats and oils are required in balanced diets for humans and animals Fatty acids are components of signal molecules and cell membranes Polyunsaturated fatty acids are essential for healthy growth and development Two types of polyunsaturated fatty acids can be distinguished: Plant-type polyunsaturated fatty acids Marine-type polyunsaturated fatty acids Source: Microsoft picture database
4 LC-PUFA have scientific proven health benefits ARA: EPA/DHA: Beneficial for brain and eye development of infants Decrease the risk of cardiovascular diseases Reduce lipid levels in blood: prevent arteriosclerosis WHO Recommendation: 0,5 g/day of EPA/DHA (equals two fish meals per week) EFSA Recommendation: 0,25 g/day of EPA/DHA Typical Western diets contain 0,1 g/day of EPA/DHA Growing health awareness boosts market for EPA and DHA Increased demand in supplements (growing 10 % p. a.) Increased demand in farmed fish (growing 8 % p. a.)
5 Currently no sustainable production concept Primary producers of LC-PUFA are algae Wild fish take up LC-PUFA via the food chain Farmed fish has to be fed with fish oil Wild fish populations are limited, demand for fish oil is exceeding supply and algae fermentation is expensive Medium-term sustainable production is questionable BASF concept: Production of LC-PUFA in Canola BASF Plant Scienc Source: Microsoft picture database
6 Fish oil markets: Production & demand outlook El Nino effects Fish oil quantity In 1000 t Production held static due to volumes of wild fish and legislative measures Supply/ demand ga Aqua need 100% fishoil Other consumption Total production From 2007 there have been examples of supply/ demand issues Source: FAO & FEAP
7 Pathway in EPA/DHA Canola and source of genes 18:1 12 Desaturase Phytophthora sojae (fungi) Oleic acid 18:2 Linoleic acid 15 Desaturase Claviceps purpurea (fungi) 18:3 Linolenic acid 6 Desaturase Ostreococcus tauri (algae) 6 Elongase Physcomitrella patens (moss) 18:3 18:4 γ-linolenic acid Stearidonic acid 20:3 20:4 Dihomo-γ-linolenic acid Eicosatetraenoic acid 5 Desaturase Thraustochytrium ssp (Thraustochryd) 5 Elongase Ostreococcus tauri (algae) 5 Desaturase Thraustochytrium ssp (Thraustochryd) 20:4 Arachidonic acid (ω-6) o3 Desaturase Phytophtora infestans (fungi) 20:5 Eicosapentaenoic acid 22:5 Docosapentaenoic acid 22:6 Docosahexaenoic acid
8 Achievements Gas chromatographic analysis ARA: Target concentration achieved Field trials for regulatory dossier on-going 75 Detector response (pa) ARA 23% EPA 22% EPA: Target concentration achieved EPA/DHA: 70% of target concentration achieved Elution time (min)
9 Sustainable production of healthy oils BASF Canola oils contain healthy LC-PUFA and offer Sustainable production Cost leadership position Convenience for the customer Efficient scale up BASF Canola oils may help Aquaculture industry to continue to deliver healthy products to the customer BASF Canola oils provide a solution for healthier human nutrition
10
11 Effects of increased vegetable oil use on EPA/DHA accumulation in salmon PUFA (g/100g fillet) North Atlantic fish oil South Atlantic fish oil Percentage of fish oil in total oil requirements in salmon diet to deliver health claim levels* of EPA/DHA in farmed salm fillet % 90% 80% 70% 60% 50% 40% 30% 20% Percentage of fish oil as total oil in salmon feed Required health claim EPA/DHA levels in 100g salmon fillet needed to deliver consumers weekly requirement for EPA/DHA Fish oil can be replaced by ~ 50% canola oil without compromising EPA/DHA levels for health claims in salmon Source: EWOS
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