Biochem. q1) the amount of cholesterol lost per day is: +a.1g/day b.10g/week c.15g/day d.5g/day
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1 Biochem q1) the amount of cholesterol lost per day is: +a.1g/day b.10g/week c.15g/day d.5g/day q2) which of the following carry cholestrol to peripheral tissue : a.hdl b.ldl c.vldl d.chylomicrons q3) esterification of cholesterol is done by : +++a.fatty acid q4) which of the following is true about glycerin dinitrate! a.tolerance is common adr b.severe headache in women +++c.can be given transdermally d.it is given orally and has high bioavailability q5) the enzyme that is responsible for preventing glucose from leaving the cell is? <c+> hexokinase q6) the major fuel of cardiac muscle at rest between meals is : fatty acid q7) hmg-coa reductase: is the rate limiting enzyme in cholesterol
2 has a sterol sensing domain is embedded in the er membrane all of the listed q8) all of the following are natural products of cholesterol except: cholestyramine q9) all of the following lower serum cholesterol, except: answer :simple carbohydrate. q10) cholesterol is precursor for : answer : vitamin d q11) inherited ldl receptor abnormalities result in : a: primary hypercholesterolemia q12) all of the following are true regarding cardiac markers except: a: ck-mb is a useful cardiac marker in a late presenting chronic renal failure patient with chest pain q13) in hypertensive heart disease, all are true except: a: history of hyperlipidemia is mandatory q14)which of the following statements concerning troponins is false? <c+>troponin i subunit attached to tropomyosin. q15)which of the following reactions will produce more energy in the heart muscle? <c+>glyceraldehydes 3 phosphate to 1,3 bisphosphoglycerate. 1.which of the following has b48 e and c markers
3 answer: chylomicron remnant 2.which of the following has a low triglyceride content but a reasonably high cholesterol content (i) chylomicrons (ii) chylomicron remnants (iii)hdl (iv) (i)+(ii) answer: (ii)chylomicron remnants 3. in cardiac muscle, which of the following is not a major substrate? (i)vldls (ii)lactate (iii)aminoacids (iv)chylomicrons answer: (iii)amino acids 4.which of the following is produced as a result of the reaction of hmg-coa lyase (i)acetone (ii)acetoacetate (iii)acetyl coa (iv) (i) + (ii) (v) (ii) + (iii) answer: (v) (ii)+(iii) 5.which of the following determines that the liver is a ketone body net producer answer: 3-ketoacyl-coa transferase involved in disturbed arterial constriction and hypertension 6-which of the following cardiac markers has the longest duration in plasma after the onset of mi? myoglobin cpk-mb troponin i & t ldh1/ldh2 isoenzymes aspartate amino transferase 7-which of the following cardiac markes is used for detecting mi? myoglobin cpk-mb troponin i troponin t ldh1 isoenzymes 8-cholesterol ester of hdl can be transferred to vldl and ldl throught the action of?
4 lechitin. cholesterol acyl transferase cholesterol ester transfer protein acyl-coa-cholesterol acyltransferase vldl receptor ldl receptor 9-which of the following is not a lipoprotein? albumin chylomicron ldl hdl lipoprotein (a) 10-what will be the effect of cholesterol induced suppression of ldl receptor synthesis? decreased removal of ldl from the serum excess circulating cholesterol & cholesterol ester when the dietary intake exceeds body need. excess circulatory cholesterol deposition atherosclerosis all of the above. 11-how many acetyl-coa molecules will be produced when palmitate is b-oxidized? what is the metabolic pathway that is not involved in cardiac muscle metabolism? gluconeogenesis glycolysis tca cycle b-oxidation of fatty acid etc and oxidative phosphorylation 16-which of the following is a major metabolic pathway in the heart muscle? beta oxidation of fatty acid fatty acid synthesis anaerobic glycolysis 17-during prolonged starvation, which of the following becomes the major source for energy in heart muscle?
5 glucose lactate amino acid ketone bodies. 18-how acetoacetate is activated in the heart muscle before it can be utilized for energy? by transfer of phosphate from glucose-6-phosphate by transfer of phosphate from fructose-6-phosphate by transfer of co-a from acetyl-coa by transfer of co-a from syccinyl co-a by transfer of co-a from hmg-coa 19-which of the following heart marker is considered most significant medical practice for management of mi? lactate dehydrogenase creatine kinase aspartate aminotransferase troponins alalnine aminotransferase 20-which of the following is rich in triacylglycerol? vldl ldl hdl sex hormone binding globulins chylomicron remnants. 21-in patients with hyperlipidemias, complex carbohydrate and fibers are recommended in their diet. what do we meant by complex carbohydrate? glucose fructose sucrose lactose Amylopectins 22-which of the following called scavenger? ldl hdl vldl chylomicrons
6 23-which of the following is inhibited by high level of pyruvate? ldh 1 (m4) in muscle ldh 5 (h4) in heart ldh 2 (m3h1) in reticulocyte ldh 3 (m2h2) in lung ldh 4 (m1h3) in kidney 24-the strong association of the mediterranean diets and low incidence of chd is currently an undisputable issue. in the first place, such as association is justified by the diet being primarily characterized by.? low in saturated fat very high concertration of pufa exceptionally high p:s ratio low protein content low in cholesterol 25-which of the following ststements do/does not apply to magnesium deficiency? associate with ihd and its complications. predisposes to hypercholesterolemia probably responsible for increased plasma homocystein. it is a causative factor for obesity 26-which of the following statements is true? a. pufa are labeled as non-essential fats b. cholesterol is an essential nutrient c. cholesterol is a non-essential nutrient d. cholesterol is not nutrient e. pufa helps body tissue overcome oxidation by free radicals
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