A GLOBAL REGENERATIVE THERAPEUTICS COMPANY. A Commitment to EXCELLENCE. IMPECCABLE TRANSPLANT RECORD Unmatched in cord blood industry
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1 A GLOBAL REGENERATIVE THERAPEUTICS COMPANY A Commitment to EXCELLENCE IMPECCABLE TRANSPLANT RECORD Unmatched in cord blood industry
2 IT HAPPENS ONLY IN STEMCYTE A GLOBAL REGENERATIVE THERAPEUTICS COMPANY STEMCYTE proves to be the only company to ethically perform STEM CELL cellular therapy / Cord Blood, worldwide BEST POSSIBILITY CORD BLOOD TRANSPLANT HAPLO iden cal & PERIPHERAL TRANSPLANT BONE MARROW TRANSPLANT Highest No. of Stem Cell Bone Marrow Transplant Haplo Iden cal & Peripheral Blood Transplant Cord Blood Transplant Birth Related Stem Cells Be er Engra ment PAIN-FREE NON-INVASIVE HLA Match Only 10/10 match can cure pa ent Finding match could be difficult Even a 3,4,5,6/6 match is sufficient
3 2084+ in MAKING... Only Cord Blood (CB) Bank to Reach >>> 2084 CB Transplant Highest TNC (Possible to treat adult pa ents) Highest CD34+ (Best Engra ment)(⁴) Highest Preserved Volume (~75 ml) HYBRID+ Model (Private, Public Banking, Therapeu cs, Clinical Trials) & Worldwide shipment Chemical Free Storage PATENTED Plasma Deple on Technology (PD)(³) In-house Transplant co-ordina on team Consistently growing CBU Inventory U.S.A. A joint venture with >68 years of experience A GLOBAL REGENERATIVE THERAPEUTICS COMPANY TRANSPLANT SUPPORT FREE Addi onal Unit (from our own inventory)* Free Replacement Unit* Safeguard Unit* Life Saver Guarantee Cer ficate* Disaster Relief Benefits* Free Unit in case - Unit is unsuitable due to Gene c Disorder* * Terms & condi ons apply * Refer Agreement booklets for above benefits
4 Unmatched Vitals ACHIEVEMENTS HIGHEST VOLUME STORED HIGHEST TNC & CD34 >2,084+ TRANSPLANTS WORLDWIDE(2) RECORD OF >58 DISEASES TREATED 100% HLA MATCH FROM STEMCYTE INVENTORY STEMCYTE s Single Storage Facility 19% STEMCYTE is the only company to store 75ml 4/6 9% 100% HLA Match 6/6 In-house confirmatory test before CBT 70% 5/6 2% 3/6 Contamina on FREE CBU STEMCYTE unit qualifies for transplant but 25 ml stored by others is not sufficient for transplant Transplant Probability Age 1 in 5,000 (upto 20 years) 1 in 450 (upto 70 years) ⁵ ~55% Autologous Transplant ~50% Allogenic Transplant ⁶
5 Worldwide Recogni on for CBT STEMCYTE Inc., USA Head Office: Boldwin Park, CA U.S.A 1215 CBT 1286 CBT Largest City BRAZIL with > 30 successful CBT Ethnically diverse 58 CBT population treated 318 CBT Successful transplants even in diverse ethnic group TAIWAN 168 CBT 5 CBT Australia nd 2 Highest in Successful CBT 372 CBT Reachability to the farmost continent INDIA 45 CBT 47 CBT All transplants are actually performed by STEMCYTE Experienced in worldwide shipment of CB Units to any part of the world.
6 STEMCYTE INDIA : Se ng the Bechmark in CBT HIGHEST TRANSPLANTS DONE IN SHORTEST JOURNEY
7 STORY BEHIND The Golden No % stem cells A GLOBAL REGENERATIVE THERAPEUTICS COMPANY SPECIALLY DESIGNED COLLECTION KIT TRANSPORTED TO LAB A GLOBAL REGENERATIVE THERAPEUTICS COMPANY Whole Cord Blood Chemical Free Buffy Coat Centrifugation Highest (7) TNC nrbcs Plasma Buffy Coat RBCs ~75 ml Highest (7) CD % stem cells Plasma More nrbc = Be er, Engra ment(⁴ ⁷) (3,7)
8 STEMCYTE WORLDWIDE :, Spectrum of Diseases Treated(⁸ ⁹) Immune Disorders Severe Combine Immune Deficiency(SCID) Wiskott-Aldrich Syndrome(WAS) Leukemias & Lymphomas Acute Myeloblas c Leukemia/ Infan le (AML) Acute Lymphocy c Lymphoma (ALL) Chronic Lymphocy c Lymphoma (CLL) Chronic Myeloblas c Leukemia (CML) Non-Hodgkins Lymphoma (NHL) Leukocyte Adhesion Defeciency (LAD) Relapsed Bilineage Leukemia Anemia Severe aplastic anemia Fanconi Anemia Paroxysmal Nocturnal Hemoglobinuria(PNH) Pure Red Cell Aplasia Congenital Thrombocytopenia Red Cell Diseases Beta Thallassemia Sickle Cell Diseases(SCD) Hemoglobinopathies Inherited Metabolic Disorders Krabbe Disease(GLD) Hurler Syndrome(MPS-IH) Adreno leukodystrophy(ald) Metachromatic leukodystrophy(mld) Multiple Myeloma Other Rare Diseases Stroke, Ischemia Hyper IgM Syndrome Human Immuno Deficiency Virus (HIV) Dreadful Diseases Cerebral Palsy Autism Asphyxia STEMCYTE has experience to treat 58 RARE diseases 80+ Diseases can be Treated Blood Group matching not required
9 MIRACLES HAPPENED ONLY AT STEMCYTE MUCOPOLY SACCHARIDOSIS (MPS) MYELODYSPLASCTIC SYNDROME (MDS) CHRONIC GRANULOMATOUS DISEASE(CGD) kg Even a patient of 75 kg was treated with single unit CONGENITAL ERYTHROPOIETIC PORPHYRIA (CEP) GUNTER DISEASE HURLERS SYNDROME STEMCYTE EXPERTISE GRISCELLI SYNDROM WITH HLH > 100 successful transplants in Thalassemia major
10 Promising Outcome MPS VI (Mucopolysaccharidosis) Disease Free by Single CB Unit 8 Kg Neutrophil Recovered Transfusion Free Griscelli Syndrome with HLH 75 Kg Disease Free by Single CB Unit Neutrophil Recovered Transfusion Free INDIA TRANSPLANT CENTRES All India Ins tute of Medical Science - New Delhi B. L. Kapur Hospital - Delhi Gangaram Hospital - Delhi Sterling Hospital - Ahmedabad Gujarat Cancer & Research Ins tute - Ahmedabad Apollo Hospital - Ahmedabad Apollo Gleneagles Hospitals - Kolkata Deenanath Mangeshkar Hospital - Pune Ruby Hall Hospital - Pune Sahyadri Hospital - Pune Apollo Speciality Hospital - Chennai Apollo Hospital - Hyderabad
11 Bright Future Goals Clinical Trials(¹⁰) Au sm Ischemic Stroke 2 to 7 Years 18 to 90 Years UCB Autologous UCB Allogenic UCB Allogenic Dr. Joanne Kurtzberg, MD Professor, Department of Pediatrics; Chief Scien fic Officer, Robertson Clinical and Transla onal Cell Therapy Program, Duke University, USA Associa ons with Duke University, U.S. Dr. Joanne Kurtzberg Selec on criteria for associa ons: cellular therapy accredita ons (viz. FACT, AABB) & Public Banking facility Access to Heamatologists & Experienced for successful CBT Experienced in Worldwide shipment CLINICAL TRIALS st 1 in India : Mul centric Clinical Trials in Spinal Cord Injury (SCI) Ÿ Ÿ Ÿ SCI treated by STEM CELLS 3 Inves ga ng centres 18 Pa ents Future outcomes : Stroke, Au sm, Cerebral Palsy, Neuroblastoma, Asphyxia, HIV and Diabetes, etc...
12 References & Abbrevia ons blood+transplant&source=bl&ots=k0fytcm09w&sig=4mv_3unwtetod6bfjnm80vap2a4&hl=en& sa=x&ved=0ahukewjlx- TC7_LQAhUHRI8KHfnpALoQ6AEIRTAI#v=onepage&q=nrbc%20in%20cord%20blood%20transpl ant&f=false Serial No. Abbreviations Full Form 1. AABB American Association of Blood Banks 2. ANC Absolute Neutrophil Count 3. BMT Bone Marrow Transplantation 4. CBA Cord Blood Association 5. CBB Cord Blood Banking 6. CBI Cord Blood Industry 7. CBT Cord Blood Transplantation 8. CD34+h Cluster of Differentiation 9. CT Confirmatory Tests 10. FACT Foundation for the Accreditation of Cellular Therapy 11. FDA Food and Drug Association 12. GMP Good Manufacturing Practice Serial No. Abbreviations Full Form 13. Haplo Haplo Identical Transplantation 14. HLA Human Leukocyte Antigen 15. MPS VI Mucopolysaccharidosis typevi 16. MD Muscular Dystrophy 17. NABL National Accreditation Board for Testing and Calibration Laboratories 18. nrbcs Nucleated Red Blood Cells 19. PD Plasma Depletion Technology 20. SC Stem Cells 21. SCI Spinal Cord Injury 22. SCITPL StemCyte India Therapeutics Pvt. Ltd. 23. TNC Total Nucleated Cell Count 24. UCB Umbilical Cord Blood A GLOBAL REGENERATIVE THERAPEUTICS COMPANY SCITPL/18/JUN/TXFOLIO/V02
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