October 2009 H1N1 Vaccine Seminars
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1 Vaccine Storage and Distribution October 2009 H1N1 Vaccine Seminars
2 Vaccine Pandemrix GSK 2.5ml antigen; 2.5ml adjuvant 5ml reconstituted for 10 doses 50 vials (500 doses) Celvapan Baxter 5ml multidose for 10 doses 20 vials (200 doses)
3 Cold chain The cold chain is the system of transporting and storing vaccines within the safe temperature range of 2 C to 8 C. Manufacture Distribution Pharmacy Patient Practice Transport
4 Cold chain in practice Only remove from cold chain for immunisation session or use first next time Pandemrix Reconsituted vaccine must be used within 24 hours (label use by time/date) Celvapan Use within 3 hours (label use by time date) Vaccinate at site of storage or need validation Domiciliary visits need mini vaccine porter (frozen packs)
5 Hundreds at risk of disease after two-year vaccine storage blunder 9th Nov 2006 More than 2,500 patients at a Lincolnshire surgery received vaccines which may not have worked 22nd Jan 08
6 Results Overview Criteria based inspection 309 practice visits, 423 fridges Temperature logging exercise Improvements required % of practices Temp monitoring Equip/facilities Stock control Documentation Contingency arran...
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10 Equipment Guidance Pharmaceutical fridge, digital thermometer Temperature monitoring Max, min and actual temp must be recorded twice daily Act on abnormal temperature Reset thermometer Stock control H1N1 1 box maximum, weekly delivery Contingency arrangements Ordering
11 Immunisation: the importance of communication Dear Dalai Lama
12 Current Data (n=125 practices; 189 fridges) Improvements required Contingency Self audit results (n=108) % of practices Temperature Equipment Stock control Documentation
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14 Incidents Number of incidents total preventable repeat Jan - Mar 09 Apr- Jun 09 Jul - Sep est
15 Max,min,actual Investigate if not C reset twice 9 0 C for 6 days Vaccine destroyed 3,400 Records suggest thermometer not reset after baby clinic
16 H1N1 Ordering Specific order form Weekly ordering as per routine schedule Before 10 th Jan 09 Leverndale RAH After 10 th Jan 09 PDC
17 NHS GREATER GLASGOW AND CLYDE H1N1 VACCINE REQUISITION FORM Clyde Sector Fax order forms to RAH Pharmacy, Fax No , enquires to Tel No Glasgow Sector Fax order forms to Leverndale Pharmacy, Fax No , enquires to Tel No NHS GG&C Pharmacy Distribution Centre (with effect Jan10??) Fax order forms to PDC, Fax No 0141???????, enquires to Tel No 0141?????? ORDER NO... EXPECTED DATE OF DELIVERY DATE OF CLINIC. COMPLETE AND RETURN TWO COPIES, RETAINING BOTTOM COPY IN DEPARTMENT CALL No s CODE VACCINE ISSUE UNIT REQ D SENT STOCK IN PRACTICE* NHS124Z Pandermix (GSK) 500doses 1 x 50 x 2.5mL Multidose Antigen Suspension Glass Vials 2 x 25 x 2.5mL Adjuvant Emulsion Glass Vials NHS125A Celvapan (Baxter) 200doses 1 x 20 x 5mL Multidose Suspension Glass Vials ALL VACCINES MUST BE REFRIGERATED PRACTICE NAME and ADDRESS... TELEPHONE No. CLINIC/HEALTH CENTRE for DELIVERY ORDER AUTHORISED BY DISPENSED BY..DATE CHECKED BY..DATE TICK FOR NEW ORDER FROMS
18 Delivery Leverndale Monday South West and East Renfrewshire (except Barrhead and Neilston) Tuesday East Wednesday West Thursday South East Friday North VOL..usual days RAH Tues and Thursdays (tbc)
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20 Summary Storage 2 to 8C to maintain license requirements Maintain cold chain Use Vaccine Porters if necessary Observe stock rotation Don t over order vaccine Don t overfill fridges
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