U.S. National Residue Program for Meat, Poultry, and Egg Products - Update
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2 Food Safety and Inspection Service Click to edit Master title style U.S. National Residue Program for Meat, Poultry, and Egg Products - Update Kristin G. Holt, DVM, MPH FSIS Liaison to CDC Atlanta, GA October 23, 2018 USAHA Pharmaceutical Issues Subcommittee 2
3 Mission in Action We are the public health agency in the USDA responsible for ensuring that meat, poultry, and processed egg products are safe, wholesome, and accurately labeled. Our Authority Through a series of Acts, Congress empowers FSIS to inspect all meat, poultry, and processed egg products in interstate commerce. Federal Meat Inspection Act (FMIA), 1906 Agricultural Marketing Act (AMA), 1946 Poultry Products Inspection Act (PPIA), 1957 Humane Methods of Slaughter Act (HMSA), 1958 Egg Products Inspection Act (EPIA), 1970
4 One Team, One Purpose We work together to accomplish our mission of protecting public health. More than employees strong
5 All three labs are ISO and ALACC accredited FSIS Field Services Laboratories In Fiscal Year 2017, the FSIS laboratories performed over 4 million scientific analyses. FSIS Office of Public Health Science Eastern Laboratory Athens, GA Midwestern Laboratory St. Louis, MO Western Laboratory Albany, CA
6 U.S. National Residue Program (NRP) The U.S. National Residue Program (NRP) is an interagency program designed to identify, rank, and analyze for chemical contaminants in meat, poultry, and egg products. Administered by FSIS Program evaluated every year Annual Plan (aka Blue Book ) plan is posted on FSIS website Annual results (aka Red Book ) results are posted on FSIS website 6
7 NRP Goals and Purpose Provide a structured process for identifying and evaluating chemical compounds of concern in food animals Test for the presence of chemical compounds in meat, poultry, and egg products - veterinary drugs - pesticides - hormones - environmental contaminants Identify need for regulatory follow-up when a violative level of chemical residue is found 7
8 NRP Overview Food and Drug Administration (FDA) Establishes tolerances for drugs and unavoidable contaminants On-farm regulatory action Environmental Protection Agency (EPA) Establishes tolerances for pesticides Food Safety and Inspection Service (FSIS) Analyzes animal tissues Prevents chemically adulterated product from entering food supply 8
9 Residue Groups MOU - Memorandum of Understanding: Working relationship between FSIS, FDA, EPA, AMS to coordinate regulatory activities for residues FSIS consults mainly with FDA and EPA, as needed, to share and compare updated information on regulations IRCG - Interagency Residue Control Group: FSIS/FDA/EPA/AMS/ CDC/ARS/APHIS Monthly meetings for updates and collaborating relative to the NRP SAT - Surveillance Advisory Team: Interagency committee that determines the chemical compounds and production classes of public health concern 9
10 NRP Residue Violation A residue violation occurs when a chemical residue is confirmed in food animal tissue and is in excess of an established tolerance or is a substance not approved for that production class 10
11 NRP Process FSIS Inspection Program Personnel (IPP) collect samples of meat, poultry, and egg products at federally inspected establishments. Samples are analyzed at FSIS laboratories for chemical residues of veterinary drugs, pesticides, and environmental contaminants. Laboratory confirmed results are compared with tolerances established by the FDA and the EPA to prevent adulterated meat from entering into commerce. 11
12 Inspector-Generated Sampling Program NRP Domestic Scheduled Sampling Plans Headquarters-generated Across all slaughter classes Samples sent to FSIS laboratories: Eastern Laboratory in Athens, GA Western Laboratory in Albany, CA Each sample is tested by all analytical methods in that lab. Muscle is analyzed first. If positive, then target tissue is analyzed. 12
13 Inspector-Generated Sampling Program NRP Domestic Inspector Generated Sampling Plans FSIS Inspection Program Personnel (IPP) conduct kidney inhibition swab (KIS ) test when they suspect that animals may have violative levels of chemical residues Positive samples are sent to the Midwestern Laboratory in St. Louis for confirmation Carcass/meat is condemned if the a residue violation is found 13
14 Inspector-Generated Sampling Program NRP Import Sampling Plans Samples are collected at ports of entry Both raw and processed products are tested Starting 2019 processed products will be tested only from Countries that are ONLY eligible to export processed products Countries that have not exported raw products during the previous fiscal year. Any country/species combinations projected to export less than 10 lots of raw product to the U.S. 14
15 Analytical Chemistry Capabilities of the Laboratories Midwestern Laboratory NRP Inspector-generated residue analysis Multi-residue Method /Aminoglycosides (MRM/AMG) Scheduled chemistry analysis Sulfonamides Eastern Laboratory and Western Laboratory NRP Scheduled chemistry analysis Eastern Lab MRM/AMG, Trace Metals, Arsenic, Avermectins, Hormones, Food Chemistry Western Lab MRM/AMG, Pesticides, Carbadox, β-agonists, Nitrofurans 15
16 NRP Information FSIS Chemistry Laboratory Guidebook es-and-procedures/guidebooks-and-methods/chemistry-laboratoryguidebook 16
17 NRP Domestic Scheduled Samples Results Year Number of Samples # of Lab Confirmed Violative Carcasses # of Lab Confirmed Non-Violative Positive Analysis FY , FY , FY , FY , *FY2018 (Preliminary) 7, Source: FSIS Data Warehouse (DW) & Public Health Information System (PHIS) * Preliminary Results 17
18 NRP Inspector Generated Sampling Results KIS TM Screen test Results Year Number of Inplant KIS Screens Tests Number of Inplant KIS Screens Positive Tests FY ,516 4,859 FY ,010 4,022 FY ,184 3, 649 FY ,138 4,162 *FY ,784 3,912 # of Lab confirmed violative Analytes / (Number of violative Carcasses) 1,384 / (1,125) 1,017/ (792) 883/ (724) 843 / (681) 806 / (660) # of Lab confirmed Non-violative Positive Analytes 1, Source: FSIS Data Warehouse (DW) & Public Health Information System (PHIS) * Preliminary Results 16
19 NRP KIS TM Screen Positive tests and Lab Confirmed Results (carcass) 6,000 4,000 4,859 5,000 4,000 4,022 3,649 4,162 3,912 3,000 3,000 2,000 2,000 1,000 1, ,000 0 FY2014 FY2015 FY2016 FY2017 *FY2018 KIS Screen Postive Confirmed Lab Violative KIS Sample - Source: FSIS Data Warehouse (DW) & Public Health Information System (PHIS) * Preliminary Results 17
20 NRP Information Additional National Residue Program information including sampling plans and residue sample results: 20
21 Questions 21
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