Application of Sabin-IPV in Eradication of Poliomyelitis
|
|
|
- Dennis Flowers
- 6 years ago
- Views:
Transcription
1 Application of Sabin-IPV in Eradication of Poliomyelitis Shi Li Institute of Medical Biology, Chinese Academy of Medical Sciences March 9, Taipei workshop
2 The first OPV(Dragee candy ) was develop by Dr. Gu Fangzhou s team in 1962.
3 Found in Involved in basic & applied researches in fields related to development of new vaccines for human infectious diseases. Large-scale production of series of polio vaccines, hepatitis A vaccines, EV71 Vaccine, etc. Postgraduates education of Peking Union Medical College. Jiao Ling Road: R & D center Ma Jin Pu: Industrialization production base Hua Hong Dong: ABSL3/4 labs Yi Lu Cun: Laboratory Animal Center
4 Make a great contribution to polio control and eradication and maintaining polio-free status in China. Over 6 billion doses OPV supplied since 1960s. WHO wrote a letter to compliment our contribution. Play an essential role in controlling epidemics and reducing incidence of hepatitis A in China. Develop the 1st viral vaccine: HAV Over 200 million doses supplied since
5 Live Attenuated HAV OPV(Dragee Candy) Sabin IPV EV71 Inactivated Vaccine OPV
6 double lock attenuated strains + inactivation
7 Started in 1983 Got approval for clinical trials (phase I & II) in 2007 Started phase I clinical trial in Aug Started phase II clinical trial in Jul Got approval for phase Ⅲ clinical trial in Aug, 2011 Finished phase Ⅲ clinical trial in Oct., 2012 GMP inspection was from May to Dec., 2014 Licensed in Jan.14th, 2015 WHO Prequalification Designing Initiated in 2015
8 Trial Plan: Random Blind Positive control Number: 1200 infants in 2 months old Group: sipv 600 infants 581 at end wipv 600 infants 573 at end Blood: Before immunization 1 month after third dose Lab. Test: Neutralizing antibody by NIFDC of China
9 不良反应发生率 Safety:No serious adverse events occur related to sipv. 不良反应发生情况 sipv cipv 级 2 级 3 级 1 级 2 级 3 级 全身性 局部性 Guoyang Liao, et al. The Journal of Infectious Diseases, 2016,214,1728~1734.
10 Ⅰ Ⅱ Ⅲ sipv wipv The seroconversion rate of anti-polioviruses types Ⅰ Ⅱ Ⅲ in sensitive subjects after vaccination Ⅰ Ⅱ Ⅲ sipv wipv The seroconversion rate of anti-polioviruses types Ⅰ Ⅱ Ⅲ in in non sensitive subjects after vaccination Guoyang Liao, et al. The Journal of Infectious Diseases, 2016,214,1728~1734.
11 GMT 100 sipv wipv 10 1 Ⅰ Ⅱ Ⅲ Guoyang Liao, et al. The Journal of Infectious Diseases, 2016,214,1728~1734.
12 GMT 100 sipv wipv 10 1 Ⅰ Ⅱ Ⅲ Guoyang Liao, et al. The Journal of Infectious Diseases, 2016,214,1728~1734.
13 Cross Neutralization Test Tested by US CDC Clinical Infectious Diseases, 2017, DOI: /cid/cix110 on line
14 Cross Neutralization Test Tested by Chinese CDC Clinical Infectious Diseases, 2017, DOI: /cid/cix110 on line
15 Inoculation of the 1st dose of Sabin-IPV Around 10 million doses supplied to domestic market until now
16 S-IPV Production Base (Phase II) Progress Kind Support by Gates foundation and DCVMN The foundation will provide financial and technical support for the pursuit of WHO prequalification of sipv.
17 S-IPV Production Facility (Phase II) Total Investment: 350 million RMB Area: m 2 First floor: two filling lines (Vials and prefilled syringes), clean utilities, packaging area; Second floor: sipv bulk production area; Capacity: Vials (both single dose and 5-dose presentations): 40 million /year Syringes: 20 million /year Designer: Eleventh Design & Research Institute of IT Co., Ltd (EDRI)
18 Sabin IPV base 2 Foundation Stone Laying Ceremony Laying the foundation stone means that IMBCAMS has found the financial means to expand production of Sabin IPV, making this great vaccine available to more children. Lance Rodewald WHO Office in China
19 Inoculation of the 1st dose of Inactivated Enterovirus 71 vaccine (Human Diploid Cell) Around 4 million doses supplied to domestic market until now.
20 Innovation ability for sustained development of new vaccines sipv-dtap combined vaccine, Rabies vaccine, HPV, HCV, etc Pre-clinical Clinical phase I EV71 inactivated vaccine, New mumps vaccine Clinical phase II sipv, bopv human diploid cell), Clinical phase III JE inactivated vaccine, Influenza Industrialization
21 Thank you for your time!
EV71 Vaccine Development. Weining Meng June 9 th, 2016
EV71 Vaccine Development Weining Meng June 9 th, 2016 Outline Epidemic of EV71-associated HFMD Development of Sinovac s EV71 Vaccine, Inlive Phase III Trial Design and Outcome Industrialization of EV71
Quality, safety and standards for poliomyelitis vaccines
Quality, safety and standards for poliomyelitis vaccines 7 th WHO/UNICEF consultation Geneva, 30 October 2008 Jackie Fournier-Caruana, WHO/QSS 1 Expert Committee on Biological Standardization The ECBS
WHO/PQT Updates on WHO Prequalification Priorities and Regulatory Systems Strengthening work
WHO/PQT Updates on WHO Prequalification Priorities and Regulatory Systems Strengthening work Dr Drew Meek Prequalification Team Regulation of Medicines and other Health Technologies Essential Medicines
Polio vaccines and polio immunization in the pre-eradication era: WHO position paper. Published in WER 4 June, 2010
Polio vaccines and polio immunization in the pre-eradication era: WHO position paper Published in WER 4 June, 2010 Epidemiology & Background Poliomyelitis (polio) is an acute communicable disease of humans
Revisiting Old and Addressing Current Issues on Vaccines: POLIO
Revisiting Old and Addressing Current Issues on Vaccines: POLIO Maria Carmen B. Nievera MD Fellow, Pediatric Infectious Disease Society of the Philippines Fellow, Philippine Pediatric Society Regional
Expanded Programme on Immunization (EPI)
Timor-Leste 217 Expanded Programme on Immunization (EPI) FACT SHEET Acronyms AD Auto disable MCV1 First dose measles containing vaccine AEFI Adverse events following immunization MCV2 Second dose measles
Feasibility of Production of Human AI Vaccine in AI vaccine Manufacturers in China. Gu Hong Ministry of Agriculture of P. R. China
Feasibility of Production of Human AI Vaccine in AI vaccine Manufacturers in China Gu Hong Ministry of Agriculture of P. R. China AI -- common challenge to the all countries Global cooperation in control
Heat and Freeze Sensitivity of Vaccines
Heat and Freeze Sensitivity of Vaccines DCVMN Workshop "Vaccine quality management systems for manufacturing excellence" Michael Rush, MBA Executive Director - Global Health Policy October 24-25, 2013
Creating VaCCines, ProteCting Life
Creating VaCCines, ProteCting Life PreVenting Disease through VaCCination a Constant BattLe Immunization has been a great public health success story. The lives of millions of children have been saved,
Prequalification Team WHO PUBLIC INSPECTION REPORT Vaccine Manufacturer
20, avenue Appia CH-1211 Geneva 27 Switzerland Tel central +41 22 791 2111 Fax central +41 22 791 3111 www.who.int Part 1: General information Name of Manufacturer Prequalification Team WHO PUBLIC INSPECTION
History and aims of immunisation. Dr Anna Clarke Department of Public Health Dr. Steevens Hospital Dublin 8
History and aims of immunisation Dr Anna Clarke Department of Public Health Dr. Steevens Hospital Dublin 8 Objectives To examine the history of immunisation To explain the aim of immunisation To develop
NVI Experience and Concept of Central Technology Hub
NVI Experience and Concept of Central Technology Hub Jan Hendriks Netherlands Vaccine Institute (NVI) MSF/Oxfam Consultation improving access and stimulating vaccine development for use in resource pour
SANOFI PASTEUR, LEADING PROVIDER OF SEASONAL INFLUENZA VACCINES
FACT SHEET SANOFI PASTEUR, LEADING PROVIDER OF SEASONAL INFLUENZA VACCINES WORLD S LEADING INFLUENZA VACCINE MANUFACTURER Annual production capacity of Sanofi Pasteur seasonal influenza vaccines have doubled
DCVMN AND VACCINE SECURITY IN ASEAN REGION. ASEAN Countries on Opportunities for Regional Vaccine Security 1-3 October, 2014.
DCVMN AND VACCINE SECURITY IN ASEAN REGION ASEAN Countries on Opportunities for Regional Vaccine Security 1-3 October, 2014. Phuket - Thailand Developing Countries Vaccine Manufacturers Network (DCVMN)
Global Overview Polio Partners Group, December Note: Gavi requirements of $122.2 million are not included in this slide
Global Overview Polio Partners Group, December 2015 1 Note: Gavi requirements of $122.2 million are not included in this slide The Polio Endgame Plan 1. Poliovirus detection & interruption 2. OPV2 withdrawal,
Managing cost considerations and access to technology for cost effective vaccine manufacture in developing countries.
Managing cost considerations and access to technology for cost effective vaccine manufacture in developing countries. Amol R. Dindokar Serum Institute of India ltd. Overview Disease Control Priorities
topv to bopv FACTSHEET 25 APRIL 2016
topv to bopv FACTSHEET th 25 APRIL 2016 POLIO FREE INDIA POLIO FREE WORLD Polio immunization is important Polio is a crippling disease that can permanently paralyze any part of the body especially the
Programme update. Prequalification of Vaccines
Programme update Prequalification of Vaccines UN Prequalification of Medicines, Diagnostics and Vaccines 6th Consultative Stakeholder Meeting 4 April 2011 David Wood, WHO/IVB/QSS Outline Good news - A
AIDA M. SALONGA, MD, FPNA, FCNSP CHAIR, AFP EXPERT PANEL, DOH MEMBER, REGIONAL CERTIFICATION COMMITTEE, WHO
POLIO FAQs on ENDGAME Tuberculosis AIDA M. SALONGA, MD, FPNA, FCNSP CHAIR, AFP EXPERT PANEL, DOH MEMBER, REGIONAL CERTIFICATION COMMITTEE, WHO OBJECTIVES Brief history of poliomyelitis Polio eradication:
VACCINE MARKETS OVERVIEW SESSION
VACCINE MARKETS OVERVIEW SESSION Robyn Iqbal Program Officer, Vaccine Delivery Market Dynamics UNICEF SD Manufacturers Meeting Copenhagen October 8, 2014 DRAFT Bill & Melinda Gates Foundation DISCUSSION
Total population 24,759,000. Live births (LB) 342,458. Children <1 year 337,950. Children <5 years 1,698,664. Children <15 years 5,233,093
DPR Korea 4 Immunization system highlights There is a comprehensive multiyear plan (cmyp) for immunization covering -5. A standing national technical advisory group on immunization (NTAGI) with formal
Global Polio Eradication & Endgame Strategy. December 2015
Global Polio Eradication & Endgame Strategy December 2015 Poliovirus detection & interruption OPV withdrawal, IPV introduction, RI strengthening Containment & Global Certification Legacy Planning Polio
CHILDHOOD VACCINATION
EPI (3) Age of Child How and Where is it given? CHILDHOOD VACCINATION Nicolette du Plessis Block 10 28/02/2012 10 weeks DTaP-IPV/Hib (2) Diphtheria, Tetanus, Acellular pertussis, Inactivated polio vaccine,
Expanded Programme on Immunization (EPI)
Indonesia 217 Expanded Programme on Immunization (EPI) FACT SHEET Acronyms AD Auto disable MCV1 First dose measles containing vaccine AEFI Adverse events following immunization MCV2 Second dose measles
Why still Polio Donato Greco ECDC polio consultant 14 April 2016
Why still Polio Donato Greco ECDC polio consultant 14 April 2016 A medical student with the last texbook on Communicable diseases! Where there is no chapter on Poliomielitis!!! What can I say o Background
Immunizations are among the most cost effective and widely used public health interventions.
Focused Issue of This Month Recommended by the Korean Pediatric Society, 2008 Hoan Jong Lee, MD Department of Pediatrics, Seoul National University College of Medicine E mail : hoanlee@snu.ac.kr J Korean
How and Why Vaccines Are Developed by Industry. Stanley A. Plotkin
How and Why Vaccines Are Developed by Industry Stanley A. Plotkin Merieux 2012 1 Why Vaccines are Different than Drugs 1) Given to healthy people, high safety required 2) Larger governmental role 3) Low
Polio Eradication: The Difficult Inclusion of IPV. Research, Policy and Product Development (RAP), Polio Operations & Research Department (POL)
Polio Eradication: The Difficult Inclusion of IPV Research, Policy and Product Development (RAP), Polio Operations & Research Department (POL) Overview Historical context Early inequality in case burden
Objective 2 Strengthening Routine Immunization, IPV introduction and the topv-bopv switch
Objective 2 Strengthening Routine Immunization, IPV introduction and the topv-bopv switch Polio Partners Group meeting Geneva 8 December 2014 Michel Zaffran Coordinator, WHO/EPI, IMG Co-chair On behalf
Polio post-certification strategy
1 Polio post-certification strategy SAGE Meeting, Geneva, 17 April 2018 Michel Zaffran, Director, Polio Eradication, WHO On Behalf o the GPEI Polio Eradication and Endgame Strategy 1. Poliovirus detection
Expanded Programme on Immunization (EPI)
Bhutan 2017 Expanded Programme on Immunization (EPI) FACT SHEET Acronyms AD Auto disable MCV1 First dose measles containing vaccine AEFI Adverse events following immunization MCV2 Second dose measles containing
WHO VACCINE SUPPLY & QUALITY SUPPORT FOR NATIONAL IMMUNIZATION PROGRAMMES
WHO VACCINE SUPPLY & QUALITY SUPPORT FOR NATIONAL IMMUNIZATION PROGRAMMES Immunization and vaccine development in the last decade Since the Millennium Summit in 2000, immunization substantial international
Sinovac Biotech Co Ltd. 29 Nov- 1Dec 2010 GENEVA
Sinovac Biotech Co Ltd 29 Nov- 1Dec 2010 GENEVA Sinovac Biotech Co Ltd (Nasdaq GM:SVA) Changping, Beijing Tangshan Yian Beijing Headquarters Sinovac Dalian Beijing Tangshan, Hebei Dalian, Liaoning Beijing
Sanofi Pasteur: A partner in eradicating vaccine preventable diseases and improving access to vaccines
Sanofi Pasteur: A partner in eradicating vaccine preventable diseases and improving access to vaccines 1 Vaccines: the single most effective medical intervention 2 Vaccines save lives Millions of cases
Polio Eradication Rotary s Commitment & Global Partnership. Carol Wells District 6440 EPN Chair
Polio Eradication Rotary s Commitment & Global Partnership Carol Wells District 6440 EPN Chair Session Outline Background on the history of polio infection Current status of global polio eradication Legacy
Michel BAIJOT Vice President, WW Business Development & Strategic Alliances
Technology Transfer and Vaccines: The GSK Experience WHO Workshop on Technology Transfer for Local Manufacturing Capacity of Vaccines Geneva, November 30th, 2010 Michel BAIJOT Vice President, WW Business
UNICEF Procurement Advancements DCVMN Annual Meeting Hanoi, Vietnam October 2013
UNICEF Procurement Advancements DCVMN Annual Meeting Hanoi, Vietnam October 2013 Presentation overview Scope of UNICEF procurement Overview of UNICEF procurement Vaccine market updates UNICEF procures
Expanded Programme on Immunization (EPI):
Expanded Programme on Immunization (EPI): Introduction Four to five million annual deaths could be prevented by 2015 through sustained and appropriate immunization efforts, backed by financial support.
China Human Vaccine Industry Report, May 2012
China Human Vaccine Industry Report, 2011-2012 May 2012 STUDY GOAL AND OBJECTIVES This report provides the industry executives with strategically significant competitor information, analysis, insight and
«20 Years of succesful Hepatitis A vaccines and Future perspectives» Hugues H Bogaerts MD FFPM Global Vaccine Consultant
«20 Years of succesful Hepatitis A vaccines and Future perspectives» Hugues H Bogaerts MD FFPM Global Vaccine Consultant EASL,St Petersburg June, 2012 Vaccine developed Twenty-seven diseases are now vaccine
Innovations in Human Papillomavirus Vaccine
Oct 2014 Life Health Innovations in Human Papillomavirus Vaccine Innovation 1 Topics 1. Current HPV vaccines 2. New development 3. What s next? 2 PART I CURRENT HPV VACCINES 3 Worldwide incidence of cervical
Cyprus Experience. Dr. Elena Papamichael Ministry of Health
Cyprus Experience Dr. Elena Papamichael Ministry of Health Cyprus became independent on1960. On 1974, Turkish troops invaded in the island disturbing the willing for peaceful living. Since then, Turkey
Immunization (I) Dr. Aws Alshamsan Department of Pharmaceu5cs Office: AA87 Tel:
Immunization (I) Dr. Aws Alshamsan Department of Pharmaceu5cs Office: AA87 Tel: 4677363 aalshamsan@ksu.edu.sa Objectives of this lecture By the end of this lecture you will be able to: 1 Realize the significance
Technology Transfer from the Perspective of IFPMA vaccine members
Technology Transfer from the Perspective of IFPMA vaccine members WHO Workshop on Technology Transfer for Local Manufacturing Capacity of Vaccines Michael Watson (Sanofi Pasteur) Chair of IFPMA Biologicals
Selected vaccine introduction status into routine immunization
Selected introduction status into routine infant immunization worldwide, 2003 This report summarizes the current status of national immunization schedules in 2003, as reported by Member States in the /UNICEF
CALIFORNIA CODE OF REGULATIONS TITLE 17, DIVISION 1, CHAPTER 4
CALIFORNIA CODE OF REGULATIONS TITLE 17, DIVISION 1, CHAPTER 4 Article 1. Definitions 6000. Admission. Admission means a pupil's first entry in a given public or private elementary or secondary school,
TAKEDA VACCINES INNOVATION FOR GLOBAL IMPACT. RAJEEV VENKAYYA, MD President, Global Vaccine Business Unit
TAKEDA VACCINES INNOVATION FOR GLOBAL IMPACT RAJEEV VENKAYYA, MD President, Global Vaccine Business Unit OUR MISSION Develop and deliver innovative vaccines that tackle the toughest problems in public
Expanded Programme on Immunization (EPI)
Sri Lanka 217 Expanded Programme on Immunization (EPI) FACT SHEET Acronyms AD Auto disable MCV1 First dose measles containing vaccine AEFI Adverse events following immunization MCV2 Second dose measles
9/11/2018. Polio and Polio Vaccine. Poliomyelitis Disease. Poliovirus. First outbreak described in the U.S. in 1843
Centers for Disease Control and Prevention National Center for Immunization and Respiratory Diseases Polio and Polio Vaccine Chapter 18 September 2018 Photographs and images included in this presentation
Update on WHO Global Action Plan for containment of polioviruses (GAPIII/ CCS)
Developing Countries Vaccine Manufacturers Network 17 th Annual Meeting Buenos Aires, Argentina, 26 October 2016 Update on WHO Global Action Plan for containment of polioviruses (GAPIII/ CCS) Jackie Fournier-Caruana
Changes for the School Year. The addition of NINTH grade to the requirement for four (4) doses of diphtheria, tetanus, and pertussis.
February 19, 2013 Dear Immunization Provider: In accordance with South Carolina Code of Laws, Section 44-29-180, and State Regulation 61-8, the 2013-2014 "Required Standards of Immunization for School
Eradicating Polio: Why and How? Dr Roland Sutter, World Health Organization 20 September 2011
Eradicating Polio: Why and How? Dr Roland Sutter, World Health Organization 20 Why? Polio Crippled for life Primarily affects children We have a historic opportunity. Preventable with vaccine 1955: polio
The Science of Vaccines:
The Science of Vaccines: Addressing Common Concerns Paul A. Offit Division of Infectious Diseases Children s Hospital of Philadelphia Perelman School of Medicine The University of Pennsylvania Are vaccines
Preparing for the withdrawal of all oral polio vaccines (OPVs): Replacing trivalent OPV with bivalent OPV
Preparing for the withdrawal of all oral polio vaccines (OPVs): Replacing trivalent OPV with bivalent OPV Frequently Asked Questions February 2015 Table of Contents Rationale for OPV cessation... 2 About
Changes for the School Year
February 8, 2018 Dear Immunization Provider: In accordance with South Carolina Code of Laws, Section 44-29-180, and South Carolina Regulation 61-8, the 2017-2018 "Required Standards of Immunization for
VACCINES TRIUMPHS AND TRIBULATIONS. William Schaffner, MD Chairman, Department of Preventive Medicine Vanderbilt University School of Medicine
VACCINES TRIUMPHS AND TRIBULATIONS William Schaffner, MD Chairman, Department of Preventive Medicine Vanderbilt University School of Medicine Never in the history of human progress has a better and cheaper
China Human Vaccine Industry Report, Jun. 2016
China Human Vaccine Industry Report, 2016-2020 Jun. 2016 STUDY GOAL AND OBJECTIVES This report provides the industry executives with strategically significant competitor information, analysis, insight
Polio and routine immunisation Alan Brooks
Polio and routine immunisation Alan Brooks Geneva, Switzerland, Background 1 History of polio eradication World Health Assembly Resolution 400 Previous eradication targets Polio cases (thousands) 300 200
Jinchang Wu, Ph.D. Director of International Affairs, Changchun BCHT March, 2013 Dubai
Jinchang Wu, Ph.D. Director of International Affairs, Changchun BCHT March, 2013 Dubai Established in March 2004 at Changchun High-tech Zone, Jilin Province, Northeast China Research, development, production
Gene Vaccine Dr. Sina Soleimani
Gene Vaccine Dr. Sina Soleimani Human Viral Vaccines Quality Control Laboratory (HVVQC) Titles 1. A short Introduction of Vaccine History 2. First Lineage of Vaccines 3. Second Lineage of Vaccines 3. New
Alternative Rotavirus Vaccine Candidates: Why should we bother?
Alternative Rotavirus Vaccine Candidates: Why should we bother? Duncan Steele Initiative for Vaccine Research, WHO 7 th International Rotavirus Symposium 12-13 June 2006, Lisboa, Portugal Rotavirus Vaccines
Collaborative procedure for licensing Prequalified vaccines
Collaborative procedure for licensing Prequalified vaccines DCVMN meeting Shanghai, China March 2015 World Health Organization, EMP/RHT/PQT rodriguezhernandezc@who.int meekd@who.int Strategic priorities
The Polio Endgame
The Polio Endgame 2013-2018 context the Endgame Plan implications for DCVMN Context 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
The switch from trivalent to bivalent oral polio vaccine. 18 th December, 2015
The switch from trivalent to bivalent oral polio vaccine 18 th December, 2015 1 Objectives of the Polio Eradication & Endgame Strategic Plan 2013-2018 1 Detect and interrupt all poliovirus transmission
SUMMARY OF PRODUCT CHARACTERISTICS
1. NAME OF THE MEDICINAL PRODUCT Poliomyelitis Vaccine, Live (Oral) 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Each dose of 0.1 ml = 2 drops contains: Polio Virus Type 1 (Sabin strain) Not less than 10
D.A.Henderson, MD, MPH. Professor of Medicine, University of Pittsburgh Honorary Fellow, London School of Hygiene and Tropical Medicine
Polio Eradication a reconsideration of strategy D.A.Henderson, MD, MPH Professor of Medicine, University of Pittsburgh Honorary Fellow, London School of Hygiene and Tropical Medicine Baltimore, Maryland
2016 NON FINANCIAL RESOURCE REQUIREMENTS GPEI DONOR CONTRIBUTIONS
2016 NON FINANCIAL RESOURCE REQUIREMENTS GPEI DONOR CONTRIBUTIONS Background The Global Polio Eradication Initiative (GPEI) is financed through a range of public and private donations. The Financial Resource
Global Health Policy: Vaccines
Global Health Policy: Vaccines Edwin J. Asturias Senior Investigator Colorado School of Public Health Department of Pediatrics Children s Hospital Colorado UNIVERSITY OF COLORADO COLORADO STATE UNIVERSITY
National Influenza Vaccine Summit. Atlanta April 12, 2008 Mitch Johnson
National Influenza Vaccine Summit Atlanta April 12, 2008 Mitch Johnson GSK s Commitment to Influenza Market Proven track record of providing influenza vaccine to global market from vaccine headquarters
Sample Collections and Poliovirus Containment: What s the Connection
Centers for Disease Control and Prevention Center for Preparedness and Response Sample Collections and Poliovirus Containment: What s the Connection October 15, 2018 Christy Myrick, PhD, RBP What s in
FORM 6-K. SECURITIES AND EXCHANGE COMMISSION Washington D.C
FORM 6-K SECURITIES AND EXCHANGE COMMISSION Washington D.C. 20549 REPORT OF FOREIGN ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of April, 2009 Commission
Development on Shigella Vaccine. Dr. Lin Du
Development on Shigella Vaccine Dr. Lin Du Dr. Kiyoshi Shiga Discoverer of the Dysentery Bacillus 1898 Disease background Disease background In 2015, estimates 2.39 billion diarrhoea episodes that cause
Biomedical Engineering for Global Health. Lecture 9 Vaccine development: from idea to product
Biomedical Engineering for Global Health Lecture 9 Vaccine development: from idea to product Review of lecture 8 Pathogens: Bacteria and Virus Levels of Immunity: Barriers First line of defense Innate
Healthy People 2020 objectives were released in 2010, with a 10-year horizon to achieve the goals by 2020.
Appendix 1: Healthy People 2020 Immunization-related Objectives Healthy People provides science-based, 10-year national objectives for improving the health of all Americans. For three decades, Healthy
Case Studies on Monitoring the Heat and Freeze Sensitive of Vaccines
Case Studies on Monitoring the Heat and Freeze Sensitive of Vaccines DCVMN Workshop "Vaccine quality management systems for manufacturing excellence" Michael Rush, MBA Executive Director - Global Health
Poliovirus Containmentfor Non Polio Facilities
61 st Annual Biological Safety Conference October 12 17, 2018 Charleston, SC. Poliovirus Containmentfor Non Polio Facilities Daphne Moffett, PhD (on behalf of the Polio Containment Team: J. Fournier Caruana,
Vaccines and other immunological antimicrobial therapy 1
Vaccines and other immunological antimicrobial therapy 1 Vaccines Vaccine: a biological preparation that provides active acquired immunity to a particular disease. Vaccine typically contains an agent that
TODAY S VACCINATION ECOSYSTEM STATUS MARKET-SHAPING PRINCIPLES, PRACTICE, IMPACT AND LESSONS LEARNT GAVI PERSPECTIVE
TODAY S VACCINATION ECOSYSTEM STATUS MARKET-SHAPING PRINCIPLES, PRACTICE, IMPACT AND LESSONS LEARNT GAVI PERSPECTIVE Aurélia Nguyen Tuesday 20 January 2015, Veyrier-du-Lac, France www.gavi.org AGENDA Market
Vaccines. Magdalena Sobieszczyk, MD, MPH Division of Infectious Diseases Columbia University. Outline
Vaccines Magdalena Sobieszczyk, MD, MPH Division of Infectious Diseases Columbia University Outline Public health impact of vaccines Historical perspective Active vs. Passive Immunization Immune system
OVERVIEW OF THE NATIONAL CHILDHOOD IMMUNISATION PROGRAMME IN SINGAPORE
OVERVIEW OF THE NATIONAL CHILDHOOD IMMUNISATION PROGRAMME IN SINGAPORE Dr Tiong Wei Wei, MD, MPH Senior Assistant Director Policy and Control Branch, Communicable Diseases Division Ministry of Health 9
Bharat Biotech. Hyderabad. Type of PAC (Supplement and Notifiable / Permission Granted by CDSCO) S. No Product
Bharat Biotech Hyderabad S. No Product Type of PAC (Supplement and / Permission Granted by CDSCO) PAC Details Date of NOC in manufacturing process of Oral Polio F.No. 12-63/BHARAT/(PACOPV)/13-BD 30.08.2013
Prospective Models of Vaccine Security Collaborations in Research and Development
Prospective Models of Vaccine Security Collaborations in Research and Development Georges Thiry, PhD IVI (International Vaccine Institute) Phuket, Oct 01, 2014 Content R&D Examples of collaborations from
Adolescent vaccination strategies
Adolescent vaccination strategies Gregory Hussey Vaccines for Africa Initiative Institute of Infectious Diseases & Molecular Medicine University of Cape Town www.vacfa.uct.ac.za gregory.hussey@uct.ac.za
Update on Vaccine Recommendations. Objectives. Childhood Immunization Schedule At the Turn of the Century. New Horizons in Pediatrics April 30, 2017
Centers for for Disease Disease Control Control and and Prevention Prevention National Center for Immunization and Respiratory Diseases Update on Vaccine Recommendations New Horizons in Pediatrics April
Table Of Contents Executive Summary Introduction to Vaccines Pediatric Preventive Vaccines
Table Of Contents Executive Summary THE GLOBAL VACCINES INDUSTRY Scope and Methodology Overview Pediatric Preventative Vaccines THE MARKET Adult Preventative Vaccines THE MARKET TOTAL MARKET ISSUES AND
VACCINE PRODUCTION IN DEVELOPING COUNTRIES: AN ECONOMIC EVALUATION
VACCINE PRODUCTION IN DEVELOPING COUNTRIES: AN ECONOMIC EVALUATION Syarifah Liza Munira, PhD Department of Economics, Faculty of Economics and Business, Universitas Indonesia liza.munira@ui.ac.id; lizamunira@yahoo.com
Vincent Racaniello
Vincent Racaniello vrr1@columbia.edu www.virology.ws Poliomyelitis Polio (grey), myelon (marrow) = Greek itis (inflammation of) = Latin A common, acute viral disease characterized clinically by a brief
PREPARATION STANDARD MATERIAL HELD AT CODE WHO/BS DOCUMENT. 1st Reference Reagent, 2009
WHO International Biological Reference Preparations Held and Distributed by the WHO International Laboratories for Biological Standards Acellular pertussis vaccine for potency assay by modified mouse challenge
1 Principles of Vaccination Immunology and Vaccine-Preventable Diseases... 1 Classification of Vaccines... 4 Selected References...
1 Principles of Vaccination Immunology and Vaccine-Preventable Diseases... 1 Classification of Vaccines... 4 Selected References... 7 2 General Recommendations on Immunization Timing and Spacing of Vaccines...
GAVI Role in IPV Introductions
GAVI Role in IPV Introductions Melissa Malhame 12 th WHO/UNICEF Consultation with OPV/IPV Manufacturers and National Regulatory Authorities Geneva, Switzerland, 10 GAVI vaccine support Currently supported
14th WHO/UNICEF Consultation with OPV & IPV Manufacturers and National Regulatory Authorities. October 29, 2015 Note for the record
14th WHO/UNICEF Consultation with OPV & IPV Manufacturers and National Regulatory Authorities October 29, 2015 Note for the record Table of Contents Table of contents... i Agenda... ii Overview......iii
Poliomyelitis: successful and critical issues in the eradication process
Vaccine Preventable Diseases in the Mediterranean Basin and Black Sea: immunization strategies and coverage in the general population and the newly arrived migrants the ProVacMed project Poliomyelitis:
Global update on temperature monitoring
Global update on temperature monitoring Why bother about temperature monitoring Objectives of the immunization supply chain Impacts of temperature excursions If undetected If detected Availability of vaccines
Towards the Achievement of GHSA 2024 s Overarching Targets
정보화파트업무계획 [GHSA] Immunization Towards the Achievement of GHSA 2024 s Overarching Targets 2016년추진업무및 2017년업무계획 ( 사업관리 ) 7 th November 2018 Korea Centers for Disease Control and Prevention I. Overview Contents
Economics of Vaccine Development A Vaccine Manufacturer s Perspective
Economics of Vaccine Development A Vaccine Manufacturer s Perspective Gerald Voss The Value of Vaccines 2 29 diseases are currently preventable by vaccination Global public health Cervical cancer 1 Diphtheria
Recommended Childhood Immunization Schedu...ates, January - December 2000, NP Central
Recommended Childhood Immunization Schedule United States, January - December 2000 Vaccines 1 are listed under routinely recommended ages. Solid-colored bars indicate range of recommended ages for immunization.
Copyright regulations Warning
COMMONWEALTH OF AUSTRALIA Copyright regulations 1969 Warning This material has been reproduced and communicated to you by or on behalf of the University of Melbourne pursuant to part VB of the Copyright
CHAPTER ONE: EXECUTIVE SUMMARY. The Global Vaccine Industry CHAPTER TWO: INTRODUCTION TO VACCINES
CHAPTER ONE: EXECUTIVE SUMMARY The Global Vaccine Industry o Scope and Methodology o Overview o Pediatric Preventative Vaccines o The Market o Adult Preventative Vaccines o The Market o Total Market o
Presentation to 13th Annual General Meeting of the DCVMN UNICEF Vaccine Forecasting
Presentation to 13th Annual General Meeting of the DCVMN UNICEF Vaccine Forecasting 1 November 2012 Deaths among children under 5 globally; 19,000 die every day from preventable causes 18% 1% 2% 2% 5%