CURRICULUM VITAE Ramya Balachandran, PhD

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1 CURRICULUM VITAE Ramya Balachandran, PhD PERSONAL Office: Medical Center East, South Tower Phone: Fax: Mail: Department of Otolaryngology 7209 Medical Center East, South Tower st Avenue South Nashville, TN EDUCATION BE in Computer Science 2001 University of Madras, Chennai, India MS in Computer Science 2003 Vanderbilt University, Nashville, USA PhD in Computer Science 2008 Vanderbilt University, Nashville, USA PhD Thesis: Measurement and Analysis of Error in Rigid-Body Point-Based Registration Systems EXPERIENCE Sept 2001-Dec 2007 Graduate Research Assistant, Medical Image Processing Laboratory, Vanderbilt University Sept 2005-Dec 2005 Teaching Assistant, Department of Electrical Engineering and Computer Science, Vanderbilt University Jan 2008-March 14, 2008 Graduate Research Assistant, Department of Otolaryngology, March 15, 2008 June 30, 2008 Research Fellow, Department of Otolaryngology, Vanderbilt University Medical Center July 1, 2008 present Research Assistant Professor, Department of Otolaryngology, MEMBERSHIPS 2008-present 2009-present 2009-present SPIE IEEE IEEE Women in Engineering PUBLICATIONS Journal Papers 1. Z Cao, S Pan, R Li, R Balachandran, J. M. Fitzpatrick, W. C. Chapman., B. M. Dawant, Registration of Medical Images Using an Interpolated Closest Point Transform: Method and Validation, Medical Image Analysis, 8, (Dec 2004). 2. R. F. Labadie, P Choudhury, E Cetinkaya, R Balachandran, D. S. Haynes, M Fenlon, S Juscyzk, J. M. Fitzpatrick, Minimally-invasive, image-guided, facial-recess approach to the middle ear: 1

2 Demonstration of the concept of percutaneous cochlear access in vitro, Otology and Neurotology, 26, (July 2005). 3. F. M. Warren, R Balachandran, J. M. Fitzpatrick, R. F. Labadie, Percutaneous cochlear access using bone-mounted, customized drill guides: demonstration of concept in vitro, Otology and Neurotology, 28(3), (Apr 2007). 4. R. F. Labadie, J. H. Noble, B. M. Dawant, R Balachandran, O Majdani, J. M. Fitzpatrick, Clinical Validation of Percutaneous Cochlear Implant Surgery: Initial Report, The Laryngoscope, 118(6): (June 2008). 5. R Balachandran, J. M. Fitzpatrick, R. F. Labadie, Accuracy of Image-guided Surgical Systems at the Lateral Skull Base as Clinically Assessed Using Bone-Anchored Hearing Aid Posts as Surgical Targets, Otology and Neurotology, 29(8), (Dec 2008). 6. R Balachandran, J Mitchell, B. M. Dawant, J. M. Fitzpatrick, Accuracy evaluation of MicroTargeting platforms for deep-brain stimulation using virtual targets, IEEE Transactions on Biomedical Engineering, 56(1), (Jan 2009). 7. R. F. Labadie, J Mitchell, R Balachandran, J. M. Fitzpatrick, Customized, Rapid-Production Microstereotactic Table for Surgical Targeting: Description of Concept and In-vitro Validation, International Journal of Computer Assisted Radiology and Surgery, 4(3), (May 2009). 8. B Bodenheimer, B Williams, M. R. Kramer, K Viswanath, R Balachandran, K Belynne, G Biswas, Construction and Evaluation of Animated Teachable Agents, Educational Technology & Society, 12 (3), (July 2009). 9. R. F. Labadie, R Balachandran, J Mitchell, J. H. Noble, O Majdani, B. M. Dawant, M Bennett, D. S. Haynes, J. M. Fitzpatrick, Clinical Validation Study of Percutaneous Cochlear Access Using Patient Customized Micro-Stereotactic Frames, Otology and Neurotology, 31(1), (Jan 2010). 10. U Lahiri, R. F. Labadie, C Liu, R Balachandran, O Majdani, N Sarkar, A Step Towards Identification of Surgical Actions in Mastoidectomy, IEEE Transactions on Biomedical Engineering 57(2), (Feb 2010). 11. R Balachandran, J. E. Mitchell, G Blachon, J. H. Noble, B. M. Dawant, J. M. Fitzpatrick, R. F. Labadie. Percutaneous Cochlear Implant Drilling via Customized Frames: an in vitro study, Otolaryngology Head and Neck Surgery 142(3), (March 2010). 12. G. B. Wanna, R Balachandran, O Majdani, J Mitchell, R. F. Labadie, Percutaneous Access of the Petrous Apex In Vitro Using Customized Drill Guides Based on Image Guided Surgical Technology, Acta Oto-Laryngologica, 130(4), (April 2010). 13. S Baron, H Eilers, B Munske, J. L. Toennies, R Balachandran, R. F. Labadie, T Ortmaier, R. J. Webster. Percutaneous inner-ear access via an image-guided industrial robot system, Journal of Engineering in Medicine, Special issue on Image-Guided Surgery, 224(5), (May 2010). 14. R Balachandran, B. E. Welch, B. M. Dawant, J. M. Fitzpatrick. Effect of MR Distortion on Targeting for Deep-Brain Stimulation, IEEE Transactions on Biomedical Engineering, 57(7), (July 2010). 15. A Danilchenko, R Balachandran, J. L. Toennies, S Baron, B Munske, J. M. Fitzpatrick, T. J. Withrow, R. J. Webster III, R. F. Labadie, Robotic Mastoidectomy, Otology and Neurotology, 32(1), (Jan 2011). 16. R Balachandran, D Schurzig, J. M. Fitzpatrick, R. F. Labadie, Evaluation of portable CT scanners for otologic image-guided surgery, International Journal of Computer Assisted Radiology and Surgery (in press). 17. L. B. Kratchman, G. S. Blachon, T. J. Withrow, R Balachandran, R. F. Labadie, R. J. Webster, Design of a bone-attached parallel robot for percutaneous cochlear implantation, IEEE Transactions on Biomedical Engineering (in press). 2

3 Conference Papers 1. Z Cao, S Pan, R Li, R Balachandran, J. M. Fitzpatrick, W. C. Chapman, B. M. Dawant, Registration of medical images using an interpolated closest point transform method and validation, SPIE Medical Imaging 2003, San Diego, CA, Vol. 5032, (Feb 2003). 2. K Viswanath, R Balachandran, J Davis, B Bodenheimer, Effective User Interface design for Teachable Agent Systems, Proc. ACM Southeast Conference 2003, Savannah, GA, (March 2003). 3. K Viswanath, R Balachandran, M. R. Kramer, B Bodenheimer, Interface Design Issues for Teachable Agent Systems, Proc. ED-MEDIA 2004, Lugano, Switzerland, (June 2004). 4. J. M. Fitzpatrick, R Balachandran, R. F. Labadie, Bite-Block Relocation Error in Image-Guided Otologic Surgery, 7th Intl. Conf. on Medical Image Computing and Computer-Assisted Intervention, Saint-Malo, France, Lecture Notes in Computer Science 3217, , Springer-Verlag (Sept 2004). 5. R Balachandran, J. M. Fitzpatrick, R. F. Labadie, Fiducial registration for tracking systems that employ coordinate reference frames, SPIE Medical Imaging 2005, San Diego, CA, Vol. 5744, (Feb 2005). 6. R Balachandran, R. F. Labadie, J. M. Fitzpatrick, Validation of a fiducial frame system for imageguided otologic surgery utilizing BAHA bone screws, IEEE International Symposium on Biomedical Imaging 2006, Arlington, VA, (April 2006). 7. R Balachandran, R. F. Labadie, J. M. Fitzpatrick, Clinical Determination of Target Registration Error of an Image-Guided Otologic Surgical System using Patients with Bone-Anchored Hearing Aids, SPIE Medical Imaging 2007, San Diego, CA, Vol. 6509, (Feb 2007). 8. R Balachandran, J Mitchell, B Dawant, J. M. Fitzpatrick, Evaluation of targeting frames for deepbrain stimulation using virtual targets, IEEE International Symposium on Biomedical Imaging 2007, Arlington, VA, (Apr 2007). 9. R Balachandran, J. M. Fitzpatrick, The distribution of registration error of a fiducial marker in rigidbody point-based registration, SPIE Medical Imaging 2008, San Diego, CA, Vol. 6918, 69180M (Feb 2008). 10. C. C. Heath, R Balachandran, O Majdani, A Jurik, T Edwards, R. F. Labadie, J. M. Fitzpatrick, Disablement of a surgical drill via CT guidance to protect vital anatomy, SPIE Medical Imaging 2009, Lake Buena Vista, FL, Vol. 7261, 72610N (Feb 2009). 11. R Balachandran, J. M. Fitzpatrick, Iterative solution for rigid-body point-based registration with anisotropic weighting, SPIE Medical Imaging 2009, Lake Buena Vista, FL, Vol. 7261, 72613D (Feb 2009). 12. L. B. Kratchman, G. S. Blachon, T. J. Withrow, R Balachandran, R. F. Labadie, R. J. Webster, Toward Automation of Image-Guided Microstereotactic Frames: A Bone-Attached Parallel Robot for Percutaneous Cochlear Implantation, Robotics Science and Systems 2010: Workshop on Enabling Technologies for Image-Guided Robotic Interventional Procedures, Zaragoza, Spain (June 28, 2010). 13. R Balachandran, J. E. Mitchell, J Noble, G Blachon, W. W. Lipscomb, D Schurzig, D. S. Haynes, M. L. Bennett, O Majdani, B. M. Dawant, J. M. Fitzpatrick, R. F. Labadie, Percutaneous Cochlear Implantation via Image-Guided Customized Frames, Robotics Science and Systems 2010: Workshop on Enabling Technologies for Image-Guided Robotic Interventional Procedures, Zaragoza, Spain (June 28, 2010). 14. A Danilchenko, A. D. Wiles, R Balachandran, J. M. Fitzpatrick, Improved Method for Point-Based Tracking, 13th Intl. Conf. on Medical Image Computing and Computer-Assisted Intervention, Beijing, China, Lecture Notes in Computer Science 6363, , Springer-Verlag (Sept 2010). 15. R Balachandran, J. E. Mitchell, J Noble, D Schurzig, G Blachon, T. R. McRackan, R. J. Webster, B. M. Dawant, J. M. Fitzpatrick, R. F. Labadie, Insertion of electrode array using percutaneous cochlear 3

4 implantation technique: a cadaveric study, SPIE Medical Imaging 2011, Lake Buena Vista, FL, Vol. 7964, 79641E (Feb 2011). Abstracts 1. R. F. Labadie, P Choudhury, E Cetinkaya, R Balachandran, D. S. Haynes, M Fenlon, S Juscyzk, J. M. Fitzpatrick, Minimally-invasive, image-guided, facial-recess approach to the middle ear, 2004 American Otology Society-Combined Otolaryngology Spring Meeting, Phoenix, AZ (May 2004). 2. B. M. Davis, F. M. Warren, R Balachandran, D. M. Kaylie, D. S. Haynes, J. M. Fitzpatrick, R. F. Labadie, Accuracy of a Novel, Dental-Affixed, Non-Invasive Fiducial System for Use During Image- Guided, Middle Cranial Fossa Surgery In-Vitro, 2006 American Neurolotology Society-Combined Otolaryngology Spring Meeting, Chicago, IL (May 2006). 3. F. M. Warren, R. F. Labadie, R Balachandran, J. M. Fitzpatrick, Percutaneous Cochlear Access Using Bone-Mounted, Customized Drill Guides: Demonstration of Concept In-Vitro, 2006 American Otology Society-Combined Otolaryngology Spring Meeting, Chicago, IL, (May 2006). 4. R. F. Labadie, R Balachandran, J. M. Fitzpatrick, Accuracy of Image-guided Surgical Systems at the Lateral Skull Base as Clinically Assessed Using Bone-Anchored Hearing Aid Posts as Surgical Targets, 2008 American Neurotology Society-Combined Otolaryngology Spring Meeting, Orlando (May 2008). 5. R. F. Labadie, R Balachandran, J Mitchell, J Noble, O Majdani, B. M. Dawant, J. M. Fitzpatrick, Clinical Validation Study of Percutaneous Cochlear Access Using Patient-Customized, Microstereotactic Frames, 2009 American Otology Society-Combined Otolaryngology Spring Meeting, Phoenix, AZ (May 2009). 6. G. B. Wanna, R Balachandran, O Majdani, J Mitchell, R. F. Labadie, Percutaneous Access of the Petrous Apex In-Vitro Using Customized Drill Guides Based on Image Guided Surgical Technology, 2009 American Neurotology Society-Combined Otolaryngology Spring Meeting, Phoenix, AZ (May 2009). 7. RF Labadie, R Balachandran, J Noble, B Dawant, J Mitchell, O Majdani, C Megerian, M Bennett, DS Haynes, JM Fitzpatrick, Percutaneous Cochlear Implantation: Update on Clinical Validation Experiments, 12th Symposium on Cochlear Implants in Children, Seattle, Washington (June 2009). 8. R Balachandran (presenter), O Majdani, J Noble, J. E. Mitchell, B. M. Dawant, J. M. Fitzpatrick, R. F. Labadie, Percutaneous Cochlear Implant Drilling via Customized Frames, 2009 American Academy of Otolaryngology Head and Neck Surgery Foundation Annual Meeting & OTO EXPO, San Diego, CA (Oct 2009). 9. A Danilchenko, J. L. Toennies, R Balachandran, S Baron, B Munske, R. J. Webster III, R. F. Labadie, Robotic Mastoidectomy, 2010 American Otology Society-Combined Otolaryngology Spring Meeting, Las Vegas, NV (May 2010). 10. R Balachandran, D Schurzig, J. M. Fitzpatrick, R. F. Labadie, The role of portable CT scanners in image-guided surgery, 2010 Computer Assisted Radiology and Surgery, Geneva, Switzerland (June 2010). 11. T McRackan, R Balachandran, J Noble, D Schurzig, G Blachon, J Mitchell, B Dawant, J. M. Fitzpatrick, R Labadie, In-vitro validation of percutaneous cochlear implantation, 2011 Association for Research in Otolaryngology, Baltimore, MD (Feb 2011). 12. T McRackan, R Balachandran, G Blachon, R Labadie, Cadaveric percutaneous CI with AB, Cochlear, and Medel electrodes, 2011 American Academy of Otolaryngology Head and Neck Surgery Foundation Annual Meeting & OTO EXPO, San Francisco, CA (accepted for presentation in Sept 2011). 4

5 Other Presentations 1. Fiducial registration algorithm for tracking systems that employ coordinate reference frame, presented at the Graduate Research Day presentation, April 2005, Vanderbilt University. 2. Validation of a fiducial frame system for image-guided otologic surgery, presented at the Graduate Research Day presentation, March 2006, Vanderbilt University. STUDENT DIRECTION 1. Andrew Jurik, Independent Study: Drill Cut Off Via Image-Guided Position Feedback, Fall Spring Christopher C Heath, MS Thesis: Disablement of a Surgical Drill via CT Guidance to Protect Vital Anatomy, Summer RESEARCH SUPPORT Ongoing Research Support NIH: NIDCD 1R01DC Robert F. Labadie (PI) 9/19/09 9/18/13 Pediatric Percutaneous Cochlear Implantation Clinical Validation and Implementation The major goal of this study is to implement the Percutaneous Cochlear Implantation technique, which was developed for adults, for the pediatric population employing microstereotactic frames. Role: Co-Investigator NIH: R21 NS J. Michael Fitzpatrick (PI) 4/01/11 3/31/13 Apparatus for Placing Electrodes for Deep-Brain Stimulation The aim of this project is to develop a new device to improve the workflow of deep-brain stimulation surgeries and perform in vitro and in vivo validations. Role: Co-Investigator 5

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