Esterified Fatty Acid Complex

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Tabitha Haynes
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2 WHAT DOES EFAC STAND FOR? Esterified Fatty Acid Complex NOTE: Esterified (EFAC) and essential (EFAs) oils sound similar, but they ARE NOT the same.

3 Originally used for joint health, it was discovered that EFAC was also very effective for periodontal health In fact the periodontal product and the cat joint product are the exact same product! When applied to the gums, EFAC provides a true 2 for 1 benefit: gum and joint health

4 November 3rd, 2009 United States Patent 7,612,111 Esterified Fatty Acid Composition Abstract The invention... for use in the treatment and prevention of various types of arthritis and other inflammatory joint conditions, periodontal diseases and psoriasis, which avoid many of the side effects associated with known treatments....

5 How DOES EFAC Work? Inflammatory Cascade The appearance of labeled EFAC within cellular membranes, especially those of the white blood cells, coupled with inhibition of thromboxane production or receptor inhibition, suggests that EFAC influences the prostaglandin cascade and resulting inflammation.

6 Absorption 95% Dual Absoroption Oral & Topical U. of Minnesota researchers discovered that 95% of esterified oils are absorbed EFAC does not just sit on the surface, it absorbs, which is important in both dentistry and orthopedics Researchers found EFAC in all the same tissues, whether applied topically or ingested, proving TRUE dermal absorption

7 How It All Started CMO or Cetyl myristoleate became available in the mid to late 90s. The cost was approx $2000 a month when it first came out EFAC s inventor tried it and it helped a little He thought if one esterified oil helped, then what about all the other esterified oils?

Meggie It also helped his 15 yr old dog that had joint issues for 3 yrs and in the last year often had to be carried, due to the severity Within a week Meggie was running around like a puppy again

8 Meggie It also helped his 15 yr old dog that had joint issues for 3 yrs and in the last year often had to be carried, due to the severity Within a week Meggie was running around like a puppy again and lived to almost 22 years.all the while moving like a young dog It is highly unusual clinically to have reduced mobility and function for 3 years and then be OK for 6 years, especially at this very advanced age.

9 My Dad, My First EFAC Patient My Dad Broke His Heel in 5 Places 15 years ago He took glucosamine, MSM, fish oils etc for many years. He could walk 2 or 3 blocks maximum due to pain. He often appeared to be dragging his foot because he could not put much direct pressure on his heel. He started using both EFAC Cream and Capsules

10 My Dad, My First EFAC Patient The Results As a side benefit of rubbing the cream on, the stiffness in his hands disappeared after only 3 days, never to return! After a month he was walking 3 to 4 miles a day from a previous 3 block maximum, and still does today. Most importantly he had little or no pain. After a month he no longer needed the cream and continued with the capsules. This was a dramatic improvement in his quality of life.

11 Petey I had dispensed lots of EFAC for people, but Petey was the fist dog I gave EFAC. He was a friend s 15 year old shepherd X. For several months the dog had extreme difficulty getting up and usually soiled himself where he rested. After only a few days on EFAC he was able to get up much more easily and could go outside Then 6 weeks later they ran out of EFAC and Petey s difficulties returned.

12 Petey He received EFAC and in a day was OK again Then they ran out of EFAC a second and third time. Each time within a day or two after restarting he was getting up again. Coincidence? Not likely! If it happened once one might wonder about a placebo or a coincidence, but not when the same result happened 3 times in a row.

13 A Physician s Experience I received a call from a physician who used the capsules on 10 people. All 10 improved substantially and had less pain I usually see a positive response in 8 of 10...I wish it were 100%! 3 of the 10 required knee replacement. 2 of the 3 were taken off the surgical list! You will rarely, if ever, see this with glucosamine/chondroitin.

Out of the Awarded 1st Place papers presented Scripp s Conference, San Diego 2007 OBJECTIVE DATA Walking distance improved after just 2 weeks and improved with each

14 Out of the Awarded 1st Place papers presented Scripp s Conference, San Diego 2007 OBJECTIVE DATA Walking distance improved after just 2 weeks and improved with each testing Patients also reported less pain after 2 weeks and their pain levels continued to decrease over the 8 weeks. 537 feet is almost a 2 block improvement in just 6 minutes!

15 EFAC Cream Trial Journal of Rheumatology 2004 PATIENTS WERE TESTED: Before applying the cream 30 minutes after the first application 30 days after applying the cream twice daily OBJECTIVE PARAMETERS TESTED: Range of motion Ability to ascend and descend stairs Ease of getting up from a sitting position Balance of patients stepping down SUBJECTIVE PARAMETER TESTED: Pain levels

16 RESEARCH RESULTS: After 30 Minutes: pain levels decreased and the ability to perform the various tasks improved after a single application of the cream After 30 Days: patients improved after applying EFAC cream twice daily, thereby also demonstrating: LONG-TERM benefit

17 New Science, New Technology Are traditional joint products Obsolete? EFAC technology is supported by outstanding clinical trial results! Why use less effective products?

18 The Start of EFAC Periodontal The inventor had a friend who had very poor gum health (some pockets were 6 and 7 mm deep) and a number of his teeth were loose. His dentist recommended: Pulling some teeth and replacing with implants. This was to begin in 60 days. The inventor felt EFAC might be good for gums and provided him some.

19 Remarkable Results! He returned to his dentist after 30 days and the dentist was floored at the improvement The gums appeared much healthier, were no longer bleeding and some of the deep pockets were now 3 mm or normal. Plus the teeth were no longer loose! THE DENTAL IMPLANTS WERE CALLED OFF!

20 Journal of Periodontology 2009, 80: Porphyromonas Gingivalis Infection Induced EFAC Treated Infection Resolved Untreated (placebo) Infection Advances

21 Great Result, but Why? Why was the infection resolved.? EFAC is not an antibiotic/antimicrobial Possible Reason: By limiting inflammation it allows the immune system to function and overcome the infection naturally

22 Soft Tissue Attachment Probing Depth Note: 1-TDC is EFAC Do you know of any other gum products that restore tissue and reduce pockets?

23 Progression of Bone Loss is Reversed Do you know of any other dental products that restore osseous tissue and reverse bone loss?

24 Osteoclasts resorb bone EFAC limits osteoclastic activity

25 Osteoblasts build bone EFAC stimulates osteoblastic activity

26 Application of EFAC lead to the Restoration of both the Soft Tissue ligaments (pocket depth) Osseous Tissue teeth (bone density) What other substance does this? Note: NSAIDs are the opposite, as they inhibit chondrocytes

27 The Experience of your Peers I perform and teach orthopedic surgery almost daily in my practice. I firmly believe in the benefits of combining EFAC with NSAID s and Tramadol to lower the required doses of those medications and improve the clinical outcome in my patients. I see it work every day Jeff Mayo, DVM, CVLS, Diplomate ABVP Washington

28 The Experience of your Peers I have been using EFAC from Hope Science topically on my 8 year old Bouvier s gums. She had a 5 mm Pocket on right upper Canine Tooth that completely resolved itself after 4 weeks. I have been trying it on my 23 year old domestic short haired cat. Her gingivitis has greatly improved. As a side effect, she is much more active. She hasn't gone down stairs for the last 2 years. Now she goes up and down the stairs daily and went out in the backyard with the dogs. Last week she must have found a catnip toy; she was doing back flips and running around the bedroom. I highly recommend this product before and after dentals to treat gingivitis and pockets, also as a treatment for arthritis. James W Bridge DVM, CVA Dana Point, Ca

29 Subject: 8 years old Female Bouvier Tiki EFAC Periodontal Health Test Test was performed without a cleaning Conducted by James W. Bridge DVM, CVA Dana Capistrano Animal Clinic, Dana Point, Ca Baseline Grade 4 gingivitis Note: all the gums are affected

30 Week 2 Grade 3 gingivitis Week 4 Grade 2-3 gingivitis Week 6 Grade 1 gingivitis

31 Trust the Experts Dr. James Anthony BSc(Agr), DVM, MRCVS, FAVD, DAVDC, DEVDC, PAg All periodontal parameters clinically improved and the cats mouths comfort level significantly improved. I have practiced advanced veterinary dentistry since I have seen many products come on the market and offer superior claims with out any true research. When ever a new product comes to the market I am very wary and want to make sure that it does what the claim say it does. I was equally wary with esterified fatty acid complex (EFAC). I read the available research and questioned individuals using the product all of which looked and sounded good. An opportunity to do some independent research on a cat colony arose at the university I used to work for. I arranged for an in-depth study with EFAC on cats with concurrent advanced periodontal disease. I was pleasantly very surprised with the results which far exceeded my expectations for the product. All periodontal parameters clinically improved and the cats mouths comfort level significantly improved. This product was also the first I have seen to be completely palatable and acceptable to all the cats involved in our study, as well as, very simple to apply. I strongly feel that EFAC has a significant role to play in the control of periodontal disease in the cat.

32 First Do No Harm Safety Research U. of Minnesota researchers gave rats EFAC at 1300 times the regular dose and no pathology was found. This is an equivalent human dose of 3900 (3 x 1300 capsules) a day Note: Over a billion doses in people have been taken without incident.

33 When to Use Ideally clients apply EFAC to pets gums: -a week or 2 before dental work/cleaning to limit trauma -after dental work/cleaning to speed recovery -as a maintenance for optimal gum health

34 When to Use Cont: -EFAC is an option when a cleaning isn t. -EFAC Periodontal is the obvious choice with older pets that also have joint issues. -as a Wellness/Anti-aging supplement, just as one would a vitamin or fish oil. Limiting inflammation safely and naturally has several general health benefits

35 EFAC and Teeth Cleaning EFAC does not remove tartar, rather EFAC promotes gum health EFAC does not replace a cleaning, EFAC complements a cleaning

36 EFAC- TRUST the SCIENCE One Evidence-based solution for Two seemingly unrelated problems SEE the Difference for Gums FEEL the Difference for Joints

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