Medical Teacher VOLUME 39. Issue 12 (2), Taylor & Francis

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1 Medical Teacher Issue 12 (2), 2017 VOLUME 39 Taylor & Francis 2017

2 Medical Teacher, Issue 12 (2). Volume 39. Taylor & Francis, Pages Proceedings of the Journal are located in the Databases Scopus and Web of Science. Source Normalized Impact per Paper (SNIP): SCImago Journal Rank (SJR): Ranking: 9/37 (Education, Scientific Disciplines), 44/89 (Health Care Sciences & Services) Impact factor: Yr impact factor: Journal Citation Reports*, Thomson Reuters EDITOR: Professor R. M. Harden, UK MANAGING EDlTOR: Mrs Pat Lilley, UK ASSOCIATE EDITORS: Dr John Dent, UK Professor Trevor Gibbs, UK Professor Trudie Roberts, UK Professor John Sandars, UK Editorial Hoard: Dr Khalid bin Abdulrahman, Saudi Arabia Dr Glen Bandiera, Canada Professor loan Bocsan, Romania Professor Angel Centeno, Argentina Dr Andre de Champlain, USA Dr Heidi Chumley, USA Prof Peter Dieter, Germany Professor Jean d lvernois, France Dr Diane Dolmans, The Netherlands Dr Rachel Ellaway, Canada Professor Down Forman, UK Professor Shimon Glick, Israel Professor Janet Grant, UK Prof Matthew Gwee, Singapore Dr Kati Hakkarainen, Finland Professor John Hamilton, Australia Professor Marilyn Hammick, UK Professor Richard Hays, Australia Dr S. Barry lssenberg, USA Professor Debbie Jaarsma, The Netherlands Dr Janusz Janczukowicz, Poland Prof Hilliard Jason, USA Dr Sharon Krackov, USA Prolessor Sam Leinster, UK Professor Michelle McLean, Australia Dr Peter McCrorie, UK Professor William McGaghie, USA Dr Gary Mires, UK Dr Jurgen Nystrup, Denmark Dr Jordi Pales Argullos, Spain Dr Hirolaki Onishi, Japan Dr Vimmi Passi, UK Dr Nivritti Patil, Hong Kong Dr Modalena Patricio, Portugal Dr Wojciech Pawlina, USA Dr Emil Petrusa, USA Dr Subha Romani, USA Associate Professor Chris Roberts, Australia Professor Rob Sanson-Fisher, Australia Dr David Stern, USA Dr Frazier T Stevenson, USA Dr Abdulwahad Telmesani, Saudi Arabia Prof Olle ten Cate, The Netherlands Prof Cees PM van der Vleuten, The Netherlands Professor Herman van Rossum, The Netherlands Prof David Wilkinson, Australia Dr Jejfrey Wiseman, Canada Print ISSN: X Online ISSN: X Association for Medical Education in Europe, 2017 Taylor & Francis, 2017

3 Medical Teacher 1303 Raywat Deonandan, Samantha DiRaimo Demographic Profile of Travellers Seeking Reproductive Tourism Services Parag Deepak Dabir, Jens Johannes Christiansen Not to be Missed Entity: Dieulafoy s Lesion! Hamid Soori, Ali Nasermoadeli, Elaheh Ainy The Role of Graduated Drivers Licensing on Incidence and Severity of Road Traffic Injuries in Iran Rodnev P. Jones Inlectious-like Spread of an Agent Leading to Increased Medical Admissions and Deaths in Wigan (England), during 2011 and Margarita Villar Luis, Luciana Barizon Luchesi, Sara Pinto Barbosa, Karla Selene Lopez, Jair Licio Ferreira Santos Patterns of Alcohol Use among Patients Who Visited Community Emergency Care Services in Southwestern Brazil G.l. Skripkina, T.S. Mitiaeva, A.S. Bezuglov Dentin Dysplasia Type Id in a Patient with Chronic Renal Failure: a Case Report V.R. Fanarjyan, S. V. Fanarjyan Comparative assessment of clinical efficacy of various minimally invasive method of treatment of ureterolithiasis G.I. Sknpkina, A.Z. Garifullina, J.N. Tel nova Features hygiene training and education of preschool children N.M. Popova, 1. Yu. Bagmut, A.V. Titkova, N.V. Shepylieva The influence of Laprol-604 on reproductive system of rats Andrey Zavtsev, Angela Vatsenko, Nina Perederii, Nataliia Ulanovskaya-Csyba A study of dental caries problem in its biological aspect... : T.M. Popova, I.Yu. Bagmut, A.V. Titkova, Yu.K. Rezunenko, D.l. Marakushyn The evaluations of exposure to Laprol-604 during pregnancy in wistar rats Venelin Terziev, Marin Georgiev The active model of a social programme and its strategic advantage V.A. Drok Case method within individual work in training of interns in specialty Dentistry Volodymyr Hryn, Anna Lavrenko, Dmytro Lavrenko, Serhiy Dubinin, Mykola Ryabushko Topography and shapes of the cecum with intact appendix human V.A. Shevchenko, A.I. Kvilchataya, L.l. Shulga, A.F. Piminov, O.V. Lukienko, S.N. Rolik, E.A.Burian Fannacoiechnologic innovations as an important part of the content of postgraduate education оf specia 1 ists оf pharmасу V.P. Nesprvudko, U.G. Tereshchuk, I.A. Shynchukovskyy, A.M. Proschenko Determination of optimization ways of re-prothesis using various Schemes gnathological support of patients at the preparatory stage to the orthopedic correction of patients w i t h occlusive iatrogenic disorders of tooth-jaw apparatus

4 1402 Medical Teacher Andrey Zaytsev, Higher State Educational Institution of Ukraine Ukrainian Medical Stomatological Academy, Teaching Assistant, Candidate of Medical Sciences, Therapeutic Stomatology Department, Angela Vatsenko, Higher State Educational Institution of Ukraine Ukrainian Medical Stomatological Academy, Associate Professor, Candidate of Biological Sciences, Medical Biology Department, Nina Perederii, Associate Professor, Candidate of Medical Sciences, Medical Biology Department, Nataliia Ulanovskaya-Csyba, Associate Professor, Candidate of Biological Sciences, Medical Biology Department A study of dental caries problem in its biological aspect Abstract: This work has outlined biological aspect in dental caries. Previous research conducted in this direction related to genetic susceptibility of people to tooth caries and has given a positive result. Studies of our time dealing with the topic, have shown if not impossibility, but the greater complexity of genetic factor managing in tooth caries. In this article, based on an analysis of the work in which dental cavities was studied on a fairly long period of evolution of mankind, shows the ability to manage of caries process. For this purpose, presented the directions that lie ahead for the possible implementation of a better understanding of the caries process. Keywords: dental caries, biology, genetics. Introduction. A most problematic place among the modern diseases is occupied by the tooth caries. According to epidemiology reports, almost all living

5 Medical Teacher 1403 people on our Earth are suffering from dental caries [1], but there are no report of mortality. These circumstances give caries mixed social significance [2]. Therefore, in addition to researchers of this pathology in medicine, many professionals from other fields are working on it as well. For example, archaeologists and anthropologists are engaged in the study of hard tissue biological material (including jaws and teeth) [3, 4]. Some of the obtained knowledges of modern medicine cannot theoretically justified. And because these phenomena have no clinical significance, they are referred to a sort of curiosities. However, the fact that the.se "curiosities" change over time in the human population, makes us to take them seriously as well as processes involved in studying [5, 6]. Relevance. Medicine refers to the biological sciences. Biologists noted that " One of the most important conditions for enhancing the scientific level of the students' knowledge and the effectiveness of the educational process is the didactic integration of knowledge. Relevance of rational directions of integration of Medical Biology with theoretical and clinical disciplines combines with integration processes that occur in Western Europe in recent years" [7]. However, the "biological knowledge that tooth caries is caused by bacteria or disease manifestation depends on genetics, food consumption and other risk factors is not sufficient to give a good understanding of the pathology and combating dental disease. More over that cariesology itself, having a huge baggage of information being explored, clearly cannot put it into practice: caries treatment is carried out in a way that exists about two thousand years such as replacing lost tooth tissues by restorative material [8]. Allowing for the situation, researchers of caries pathology believe that failure to resolve the problem of tooth caries is at the conceptual level [9]. Therefore, it is more appropriate and relevant is the situation that integration is not only in the didactics as well as in the study of caries phenomenon involving biological scientific methods. The aim of the study: to determine the possibility of using biological scientific methods for finding the essence of caries phenomenon. Materials and methods: the literary sources are materials for study of the subject. Analysis of these literary sources and integration of knowledge serves as a method of research.

6 1402 Medical Teacher Results: the fact that tooth caries is associated with human genetics, referred to the possibility of research using biological methods. These methods apply to both organismal and population levels. Inaccessibility, but the ability to control tooth caries at these levels are not well known and are under discussion. The development of the given direction will be associated primarily with the measurement of tooth caries. Conclusions: a proven genetic determinism of tooth caries is proved. The ability to manage of caries process is proposed at the genetic level. Results and discussion. Cariesology has the knowledges obtained in the stu dy of dental caries by means of twin method. On this issue, a variety of views have been expressed in Russian-speaking literature, the most fully in the work of G. Pakhomova and co-authors. The measure of influence of genetic factors on the occurrence of disease is considered to be the ratio of the frequency of its occurrence in pairs of homozygous twins and the same indicator from heterozygous twins. Matching cases of illness (so-called concordance trait) among homozygous twins is 100% for genetic pathologies, whereas heterozygous concordance virtually zero. For diseases caused by external (damaging) factors correlation proves otherwise: in all cases equally concordance is low, regardless of twin zygocity. Between these poles of endo- and exogenous diseases are all known nosologic forms. They differ on the basis of genetic determinism, ranging from nonexistent to absolute predestination. Findings regarding tooth caries on the basis of these methodologies are unambiguous: tooth caries is largely genetically predetermined. Significant is the fact that the work of G. Pakhomova was presented as the first message. Further development of the ideas contained in.it, and not followed [9]. There is just a limited number of studies of the researches about clinical and pathogenetic mechanisms of development of caries in children with Psycho - neurological disorders (PND) presented in medical literature [10]. A study of dental status of children with PND and medico-social data passports allowed E. Denisova in 2011 year to identify the managed and unmanaged risk factors that contribute to the development of caries and periodontal disease. Managed risk factors of development of caries in children with PND author characterised as a high activity of caries microflora, increased rate of formation of tooth plaque, low resistance of tooth enamel against relatively low remineralization ability of saliva.

Medical Teacher 1405 The most important unmanaged risk of caries and periodontal disease were identified as particular somatic status of a child, socio-economic factors (e.g., low standard of living of families) and genetic factors [11].

There are 499 researches of dental caries in ancient people (from the Copper Age to the Middle Ages) served as background materials.

7 Medical Teacher 1405 The most important unmanaged risk of caries and periodontal disease were identified as particular somatic status of a child, socio-economic factors (e.g., low standard of living of families) and genetic factors [11]. In 2012, A. Artemyev was defended thesis for the degree of Candidate of Medical Sciences on the theme "The evolutionary features of development of caries in humans". There are 499 researches of dental caries in ancient people (from the Copper Age to the Middle Ages) served as background materials. The remains were found as a result of the protective archaeological excavations on the territory of Ukraine. On the basis of the data obtained, the comparative multifactorial mathematical analysis (method of pointed graphs) of pathology were completed using odontological fossil and subfossil materials [12]. According to these studies were drawn graphics. Of particular interest are the following cases: Figure 1 presents the changes in the intensity of caries from Copper Age to predict for future periods. Figure 2 presents the changes in the prevalence of caries from Copper Age to predict for future periods. Figure 1. A graph of changes in caries intensity Figure 2. A graph of changes in caries prevalence (%)

8 1406 Medical Teacher The evolution of tooth caries has been evident in the graphs. We see that carious process during its evolution in the selected range of human population has made major quantitative and qualitative changes. One can see in the Figure 1 a surge of intensity of caries process from XVII to XXI century, and then it ascent became slow. The intensity of the caries process shows the reactions of the human body. Figure 2 is very similar to Figure 1 but there are differences: in the Middle Ages the rise of the incidence of dental caries is not so dramatically, rather than its intensity. But from XXI century the rise in prevalence was also slower than the rise of intensity. The prevalence of caries process shows the reactions of the human population. Two graphics indicate another interesting thing - to the XVII century caries was a real dental caries. But from XXI century it is another qualitative phenomenon which has already found a title - carious disease. Conclusions. Drawing a conclusion, we would like to highlight the following point: 1. The statement about caries determinism has been well documented. 2. This direction in cariesology is not developed to the full extent. 3. It is likely that this situation is linked with the inability of genetic factors. 4. Changing of the caries process in the evolution of the human population indicates the ability to control, including at the genetic level. References: 1. Петрушанко T.O. Якісний склад мікробіоценозу порожнини рота осіб моло-дого віку з різною інтенсивністю карієсу / Т.О. Петрушанко, В.В. Череда, Г.А. Лобань // Світ медицини та біології С Терапевтична стоматологія: Підручник для студентів стоматологічних факультетів вищих медичних навчальних закладів IV рівня акредитації у двох томах / За редакцією проф. А.К. Ніколішина. - Т. І. - Полтава: «Диво-світ», с. 3. Бужилова А.П. Homo sapiens: история болезни // А.П. Бужилова. - М.: Языки славянской культуры, с. 4. Рохлин Д.Г. Болезни древних людей // Д.Г. Рохлин. - М.: Наука, с.

9 Medical Teacher Зайцев A.B. Антагонизм Дюбуа в современных условиях / A.B. Зайцев, Н.В. Котелевская, О.Н. Бойченко, А.К. Николишин // Український стоматологічний альманах (Т. 1). - С Окушко В.Р. К «теоретической стоматологии» / В.Р. Окушко // Новое в стоматологии С Дубінін С.І. Вирішення деяких проблем інтеграції-навчання при викладанні медичної біології/c.і. Дубінін, A.B. Ваценко, H.A. Улановська-Циба, Н.О. Передерій // Матеріали доповідей Всеукраїнської науково-практичної конференції з міжнародною участю «Суспільство і медицина: діалог в умовах євроінтеграції» (1-2 жовтня 2015 р.). - Полтава, с. С Мамедова Л.А. Кариес зубов и его осложнения (от древности до современности) / Л.А. Мамедова; под ред. В.К. Леонтьева. - М.: Медицинская книга; Н. Новгород: Изд-во НГМА, с. 5. Окушко В.Р. Наследственный фактор кариеса в качестве эпигенетического феномена / В.Р. Окушко II Інновації в стоматології С Савичук Н.О., Дзюба С.А., Степаненко Л.В. Оценка стоматологического статуса детей с психоневрологическими расстройствами // Современная стоматология С Денисова Е.Г., Олейник Е.А. Определение риска развития кариеса у детей с синдромом Дауна // Научные ведомости БелГУ. Серия «Медицина. Фармация» (111). - Вып. 15/1. - С Артем'єв A.B. Еволюційні особливості розвитку захворювань на карієс зубів у людини: автореф. дис. на здобуття ступеня канд. мед. наук: спец «Стоматологія» / A.B. Артем'єв. - Полтава, с.

Impact of dysplastic scoliosis on chemical composition of permanent teeth enamel

Impact of dysplastic scoliosis on chemical composition of permanent teeth enamel 1352 The Journal of Medicine and Philosophy Korotich N.N., Higher State Educational Establishment of Ukraine Ukrainian Medical Stomatological Academy, Poltava, Ukraine, Candidate of Medicine, Lokhmatova