SECTION 8B - OTHER PRIMARY UNUSUAL EXPERIENCES

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1 START TIME : CHECK ITEM DID SUBJECT REPT NON- BIZARRE DELUSIONS? NO - SKIP TO Q.19, 8B.1 PAGE 176 (ARE ANY OF THE FOLLOWING Q. S CODED 3 WITH SMALL BOX NOT CHECKED: SECTION 8A, Q s 1 6, PAGES ?) 1. You mentioned before that you [NON-BIZARRE DELUSIONS]. Did you take any medication for [NON-BIZARRE DELUSIONS]? Did you have any of those thoughts for at least a month? Non-bizarre delusions for 1(+) month - delusions co-occurred with hallucinations or any other category of psychotic symptoms = 1 - delusions come and go = 1 - belief is held with conviction for 1(+) month = 3 - took medication = 3 SPECIFY DELUSIONS SKIP TO Q.19, PAGE At any time, were you drug- and alcohol-free when you began having those thoughts? IF NO: At any time, were you drinking or using drugs only occasionally when you began having those thoughts? By occasionally, I mean less than 4 days a week. IF USED OCCASIONALLY: Abstinence or occasional use at onset of non-bizarre delusions - relevant substance was used less than 4 days a week or 3 days straight when delusions began = 3 - drank 4+ days a week but only small amounts of alcohol (up to 4 drinks) = 3 - all periods of delusions occurred with onset during chronic intoxication or binge use = 1 - refer to substance timeline - SKIP TO Q.4, PAGE 172 SPECIFY SUBSTANCE AND PATTERN OF USE 3. At any time, were you drug- and alcohol-free for the first month after you began having those thoughts? IF NO AND NOT KNOWN: At any time, were you drinking or using DRUG only occasionally for the first month after you began having those thoughts? IF USED OCCASIONALLY AND NOT KNOWN: Abstinence or occasional use continues during first month of non-bizarre delusions - relevant substance was used less than 4 days a week, 1 month after onset of delusions = 3 - drank 4(+) days a week but only small amounts of alcohol (up to 4 drinks) = 3 - increased use to 4(+) times a week during the first month after onset of delusions = 1 SPECIFY SUBSTANCE AND PATTERN OF USE - SKIP TO Q.6, PAGE

2 4. Were you ever drug- and alcohol-free for at least a month while you [NON-BIZARRE DELUSIONS]? IF NO: Were you ever drinking or using drugs only occasionally for at least a month while you were having those experiences? By occasionally, I mean less than 4 days a week. IF USED OCCASIONALLY: Abstinence or occasional use for 1(+) month during non-bizarre delusions - 1(+) month of delusions, in which relevant substance was used 3 days a week or less = 3 - stopped using, and delusions continued for 1(+) month = 3 - drank only small amounts of alcohol (up to 4 drinks) daily = 3 - delusions always occurred during chronic intoxication or binge use = 1 - refer to substance timeline - SKIP TO Q.6 SPECIFY SUBSTANCE AND PATTERN OF USE CHECK ITEM DID ONSET OF DELUSIONS EVER OCCUR DURING NO - SKIP TO Q.19, 8B.2? PAGE 176 (IS Q.2, PAGE 171 CODED 3?) 5. You said that you were (drug- and alcohol-free/ drinking or using DRUG only occasionally) when you began [NON-BIZARRE DELUSIONS]. How long after those thoughts began did you start drinking or using drugs heavily? By heavily, I mean 4 or more days a week or 3 days straight. Duration of abstinence or occasional use after onset of non-bizarre delusions - chronic intoxication: 4+ days a week; binge use: 3(+) days straight - if used at a chronic or binge level after onset of more than one delusional period, code longest period of abstinence or occasional use - must be less than 1 month SPECIFY PATTERN OF USE WEEKS DAYS INTERVIEWER INSTRUCTIONS: SKIP TO Q.19, PAGE Did you have more than one time like that, when you [NON-BIZARRE DELUSIONS] for at least a month when you were (drug- and alcoholfree or drinking or using DRUG occasionally)? More than one period of non-bizarre delusions - consider only primary periods 172

3 7. At (that time/any of those times), did you [NON- BIZARRE DELUSIONS] for at least 1 month, when you were not taking any medication(s)? IF ALWAYS TOOK MEDICATION(S): Which did you take? IF TOOK RELEVANT MEDICATION(S): Did you start taking [MEDICATION(S)] before you began [NON-BIZARRE DELUSIONS]? How long did you take [it/them]? Primary non-bizarre delusions in the absence of relevant prescription drug(s) - period without relevant medications must be primary - relevant medications: antihypertensives (especially reserpine), coritico-steroids (e.g., prednisone), anabolic steroids, anti-convulsants, anti-parkinsonian and antiulcer medications, oral contraceptives, cardiac medications (e.g., Digitalis, Clonidine), sulfonamide antibiotics - began taking relevant medications after onset of delusions = 3-1(+) month of primary delusions in the absence of relevant medications = 3 - SKIP TO Q.19, PAGE Were you ever exposed to any toxin or poisonous substance, like chemical spills or fumes? IF : Which one? Exposure to relevant toxin - relevant toxins: gasoline or paint fumes, carbon monoxide, carbon dioxide, nerve gas, organophosphate insecticides - SKIP TO CHECK ITEM 8B.3 9. At (that time/any of those times), did you [NON- BIZARRE DELUSIONS] for at least 1 month, when you were not exposed to [TOXIN]? IF ALWAYS EXPOSED TO TOXIN: When did that happen? Did a doctor ever say that [NON-BIZARRE DELUSIONS], were caused by [TOXIN]? Primary non-bizarre delusions without exposure to toxin - period without exposure to toxin must be primary - relevant toxins: gasoline or paint fumes, carbon monoxide, carbon dioxide, nerve gas, organophosphate insecticides - must be medical or public report that toxin caused symptoms - 1(+) month of primary delusions without exposure to relevant toxin = 3 - SKIP TO Q.19, PAGE 176 CHECK ITEM DID SUBJECT EVER HAVE A PRIMARY A SUBSTANCE-INDUCED NO - SKIP TO Q.12, 8B.3 MAJ DEPRESSIVE EPISODE A MANIC EPISODE? PAGE 174 (IS A MAJ DEPRESSIVE EPISODE DIAGNOSED IN SECTION 4A 4B 4C IS A MANIC EPISODE DIAGNOSED IN SECTION 6?) 10. At (that time/any of those times), did you [NON-BIZARRE DELUSIONS] when you were not severely (depressed/manic/soe)? Primary non-bizarre delusions in the absence of a prominent mood episode - period without a prominent mood episode must be primary - all primary delusions co-occurring with a full syndrome mood episode = 1 - if coded, 1 check box - for mixed mood episode refer to Q36, p SKIP TO Q.12, PAGE 174 CHECK ALL THAT APPLY: DEPRESSION MANIA MIXED 11. Were you very (depressed/manic/soe) the whole time you [NON-BIZARRE DELUSIONS]? Primary non-bizarre delusions always co-occurring with a prominent mood episode - had delusions without a mood episode = 1 - never had delusions without a mood episode = 3 173

4 12. At (that time/any of those times), did you [NON-BIZARRE DELUSIONS] for at least 1 month when you were not physically ill? Primary non-bizarre delusions in the absence of medical condition - period without physical illness must be primary - primary delusions for 1(+) month without physical illness = 3 - primary delusion continued 4(+) weeks after remission from physical illness = 3 - SKIP TO Q Did you have any of the following medical problems while you [NON-BIZARRE DELUSIONS]? - a brain tumor? - a stroke? - epilepsy? - thyroid problems? - liver disease? - kidney disease? IF : Did you have [MEDICAL CONDITION] before you [NON-BIZARRE DELUSIONS]? How long did you [MEDICAL CONDITION]? Relevant medical condition during non-bizarre delusions - relevant illness began before delusions and is shown to directly cause delusions = When (did you start/was the most recent time you started) having these thoughts? That is, when you were (drug- and alcohol-free/drinking or using DRUG occasionally) (and you were not physically ill or (depressed/manic/soe))? Onset of most recent primary non-bizarre delusions - code onset of most recent primary non-bizarre delusions lasting 1 (+) month (even if onset occurred during intoxication) without prescription drugs or exposure to toxin - probe for most recent period of primary symptoms in the absence of prominent mood episode and medical condition MONTHS AGE (IF AGO ME THAN 12 MONTHS) 15. Since [ONSET CODED IN Q.14], did you ever stop [NON-BIZARRE DELUSIONS] for 2 months? Primary non-bizarre delusions remitted - must be symptom-free for 2(+) months 16. During the time you [NON-BIZARRE DELUSIONS], were you having problems with people? (What kinds of problems?) at work or school? (What kinds of problems?) getting a job? taking care of your everyday responsibilities? (How?) taking care of yourself? (How?) keeping your clothes clean and neat? IF : Were the problems mild, moderate or severe? Social/interpersonal, occupational/academic, or selfcare dysfunction - for self-care, include observer s ratings - behavior is within the norms of subculture = 1 - impairment directly arises from the content of the delusional belief = 1 - functioning is below expected level due to other psychiatric problems = 1 - functioning has been below expected level, even before onset of delusions = 1 - functioning is markedly below level of functioning prior to onset = 4 - if coded 3 or 4, check area of dysfunction SPECIFY DYSFUNCTION 1 2 MILD 3 MODERATE 4 SEVERE CHECK ALL THAT APPLY: SOCIAL/INTERPERSONAL OCCUPATIONAL/ACADEMIC SELF-CARE 174

5 CHECK ITEM DID SUBJECT MEET CRITERIA F PSYCHOTIC DISDER NO 8B.4 DUE TO MEDICAL CONDITION? (IS Q.13, PAGE 174 CODED 3?) SKIP TO Q.17 CHECK ITEM DID SUBJECT MEET CRITERIA F MOOD DISDER WITH PSYCHOTIC SYMPTOMS? NO 8B.5 (IS Q.11, PAGE 173 CODED 3?) SKIP TO Q.17 CHECK ITEM DID SUBJECT MEET CRITERIA F PSYCHOTIC DISDER, NOS? NO 8B.6 (IS Q.11, PAGE 173 CODED 1 IS Q.16, PAGE 174 CODED 3 4?) SKIP TO Q.17 CHECK ITEM DID SUBJECT HAVE PRIMARY DELUSIONAL DISDER? NO 8B.7 (IS Q.16, PAGE 174 CODED 1 2?) 17. How long did you have those thoughts at that time? Duration of most recent primary non-bizarre delusions - refer to onset in Q.14 - duration is from onset to 2(+) months full remission YEARS MONTHS 18. When was the last time you had those thoughts? Offset/recency of most recent period of non-bizarre delusions - if current, code 1 DAY AGO AGE (IF ME THAN 12 MONTHS) MONTHS AGO WEEKS AGO DAYS AGO CHECK ITEM DID SUBJECT MEET CRITERIA F DELUSIONAL DISDER? NO 8B.8 (IS CHECK ITEM 8B.7 CODED?) SKIP TO SECTION 9, PAGE

6 19. You mentioned before that you [SYMPTOMS MARKED ON APPENDIX E; DO NOT INCLUDE NEGATIVE SYMPTOMS]. Was there ever a time in your life when you had any of these experiences for one day or more, but no longer than one month? IF : Which ones lasted at least a day but no longer than one month? How long did those experiences last? IF NO: How long did those experiences last? Other episode of psychotic symptom(s) lasting from 1(+) day(s) up to 1 month - all psychotic episodes already explored in 8A + 8b = 1 - only negative symptoms = 1 - symptoms must be present 24 hours or more - if coded 3 check relevant symptom boxes - specify length of symptoms SPECIFY LENGTH OF TIME SKIP TO Q.20 CHECK ALL THAT APPLY: DELUSIONS HALLUCINATIONS DISGANIZED SPEECH DISGANIZED/CATATONIC BEHAVI CHECK ITEM IS MOOD DISDER WITH PSYCHOTIC FEATURES PSYCHOTIC DISDER NOS, NO 8B.8A PSYCHOTIC DISDER DUE TO MEDICAL CONDITION ALREADY DIAGNOSED? (ARE ANY OF THE FOLLOWING CODED "": SKIP TO CHECK ITEM CHECK ITEM 8A.17, 8A.18, PAGE 169, CHECK ITEM 8B.4, 8B.5, 8B.6, PAGE 175?) 8C.1 PAGE At any time, were you drug- and alcohol-free when you began [PSYCHOTIC SYMPTOMS]? IF NO: At any time, were you drinking or using drugs only occasionally when you began (PSCYHOTIC SYMPTOMS)? (By occasionally, I mean no more than 3 days a week.) IF USED OCCASIONALLY: Abstinence or occasional use at onset of psychotic symptoms - relevant substance was used 3 days a week or less, when psychotic episode began = 3 - drank 4+ days a week but only small amounts of alcohol (up to 4 drinks) = 3 - all periods of psychotic episode occurred with onset during chronic intoxication or binge use = 1 - refer to substance timeline SPECIFY SUBSTANCE AND PATTERN OF USE - SKIP TO CHECK ITEM 8C.1, PAGE At any time, were you drug- and alcohol-free during the month before you began [PSYCHOTIC SYMPTOMS]? IF NO AND NOT KNOWN: At any time, were you drinking or using DRUG only occasionally during that month, (that is, the month before you began [PSYCHOTIC SYMPTOMS)? (By occasionally, I mean no more than 3 days a week.) IF USED OCCASIONALLY: Abstinence or occasional use during the month before onset of psychotic symptoms - relevant substance was used 3 days a week or less, 1 month before onset of psychotic episode = 3 - drank only small amounts of alcohol (up to 4 drinks) daily = 3 - If used at a chronic or binge level during the month before onset of psychotic episode, inquire about another period that can be potentially primary refer to substance timeline - SKIP TO CHECK ITEM 8C.1, PAGE Did you have more than one time like that, when you [PSYCHOTIC SYMPTOMS] and you were (drug- and alcohol-free or drinking or using DRUG occasionally)? More than one period of primary psychotic symptoms - consider only primary periods 176

7 23. At (that time/any of those times), did you [PSYCHOTIC SYMPTOMS] when you were not taking any medication(s)? IF ALWAYS TOOK MEDICATION(S): Which did you take? IF TOOK RELEVANT MEDICATION(S): Did you start taking [MEDICATION(S)] before you began [PSYCHOTIC SYMPTOMS]? How long did you take [it/them]? Primary psychotic symptoms in the absence of relevant prescription drug(s) - period without relevant medications must be primary - relevant medications: antihypertensives (especially reserpine), coritico-steroids (e.g., prednisone), anabolic steroids, anti-convulsants, anti-parkinsonian and antiulcer medications, oral contraceptives, cardiac medications (e.g., Digitalis, Clonidine), sulfonamide antibiotics - began taking relevant medications after onset of psychotic symptoms = 3-1(+) day of primary psychotic symptoms in the absence of relevant medications = 3 - SKIP TO CHECK ITEM 8C.1, PAGE Were you ever exposed to any toxin or poisonous substance, like chemical spills or fumes? IF : Which one? Exposure to relevant toxin - relevant toxins: gasoline or paint fumes, carbon monoxide, carbon dioxide, nerve gas, organophosphate insecticides - SKIP TO CHECK ITEM 8B At (that time/any of those times), did you [PSYCHOTIC SYMPTOMS] when you were not exposed to [TOXIN]? IF ALWAYS EXPOSED TO TOXIN: When did that happen? Did a doctor ever say that [PSYCHOTIC SYMPTOMS], were caused by [TOXIN]? Primary psychotic symptoms without exposure to toxin - period without exposure to toxin must be primary - relevant toxins: gasoline or paint fumes, carbon monoxide, carbon dioxide, nerve gas, organophosphate insecticides - must be medical or public report that toxin caused symptoms - 1(+) day of primary psychotic symptoms without exposure to relevant toxin = 3 - SKIP TO CHECK ITEM 8C.1, PAGE 180 CHECK ITEM DID SUBJECT EVER HAVE A PRIMARY A SUBSTANCE-INDUCED NO - SKIP TO Q.27 8B.9 MAJ DEPRESSIVE EPISODE A MANIC EPISODE? (IS A MAJ DEPRESSIVE EPISODE DIAGNOSED IN SECTION 4A 4B 4C IS A MANIC EPISODE DIAGNOSED IN SECTION 6?) 26. At (that time/any of those times), did you [PSYCHOTIC SYMPTOMS] when you were not (depressed/manic/soe)? Primary psychotic symptoms in the absence of a prominent mood episode - symptoms without prominent mood episode must be primary - psychotic symptoms always co-occurring with a mood episode = 1 - if coded 1, check box - for mixed episode refer to p. 36, p.147 CHECK ALL THAT APPLY: DEPRESSION MANIA MIXED 27. At (that time/any of those times), did you [PSYCHOTIC SYMPTOMS] when you were not physically ill? Primary psychotic symptoms in the absence of medical condition - period coded must be primary - SKIP TO Q.29, PAGE

8 28. Did you have any of the following medical problems while you [PSYCHOTIC SYMPTOMS]: - a brain tumor? - a stroke? - epilepsy? - thyroid problems? - liver disease? - kidney disease? Relevant medical condition during primary psychotic symptoms - had none of the relevant physical illness = 1 - relevant illness began before psychotic symptoms and is shown to directly cause symptoms = 3 IF : Did you have [MEDICAL CONDITION] before you began [PSYCHOTIC SYMPTOMS]? 29. When was the most recent time you started [PSYCHOTIC SYMPTOMS]? That is, when you were (drug- and alcohol-free/drinking or using DRUG occasionally) (and you were not physically ill or (depressed/manic/soe))? Onset of most recent primary psychotic episode - period coded must be primary - probe for most recent period of primary symptoms in the absence of prominent mood episode and medical condition AGE (IF ME THAN 12 MONTHS) MONTHS AGO WEEKS AGO DAYS AGO 30. Since [ONSET CODED IN Q.29], did you ever stop [PSYCHOTIC SYMPTOMS] for 2 months? Primary psychotic episode remitted - must be symptom-free for 2(+) months CHECK ITEM DID SUBJECT MEET CRITERIA F PSYCHOTIC DISDER NO 8B.11 DUE TO MEDICAL CONDITION? (IS Q.28 CODED 3?) - SKIP TO Q.31, PAGE 179 CHECK ITEM DID SUBJECT MEET CRITERIA F MOOD DISDER WITH PSYCHOTIC SYMPTOMS? NO 8B.12 (IS Q.26, PAGE 177 CODED 1?) - SKIP TO Q.31, PAGE 179 CHECK ITEM DID SUBJECT MEET CRITERIA F PSYCHOTIC DISDER, NOS? NO 8B.12A (IS Q.19, PAGE 176 Q.30 CODED 1?) - SKIP TO Q.31, PAGE 179 CHECK ITEM DID SUBJECT MEET CRITERIA F PRIMARY BRIEF PSYCHOTIC EPISODE? NO 8B.13 (IS Q.30 CCODED 3?) 178

9 31. In your entire life, when was the first time you had those experiences when you were (drug- and alcohol-free/drinking or using DRUG occasionally)? Onset of initial episode of primary psychotic disorder in lifetime - period coded for onset must be primary AGE (IF ME THAN 12 MONTHS) MONTHS AGO WEEKS AGO DAYS AGO 32. When was the last time you had any of those experiences? Offset/recency of most recent primary psychotic disorder - if current, code 1 DAY AGO AGE (IF ME THAN 12 MONTHS) MONTHS AGO WEEKS AGO DAYS AGO CHECK ITEM DID SUBJECT MEET CRITERIA F BRIEF PSYCHOTIC EPISODE? NO 8B.14 (IS CHECK ITEM 8B.13, PAGE 178 CODED?) SKIP TO SECTION 9, PAGE 181 END TIME : 179