CURRICULUM VITAE. Steven K. Grekin, D.O., F.A.O.C.D. Board Certified in Dermatology

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1 CURRICULUM VITAE Steven K. Grekin, D.O., F.A.O.C.D. Board Certified in Dermatology Grekin Skin Institute East Twelve Mile Road Warren, Michigan Fax EDUCATION Doctor of Osteopathic Medicine University of Osteopathic Medicine and Health Sciences Des Moines, Iowa Bachelor of Science/ Gerontology University of Michigan Ann Arbor, Michigan POST GRADUATE EDUCATION Jan Jan 1994 Dermatology Residency Chief Resident Bi-County Community Hospital Warren, Michigan July 1989-June 1990 Rotating Internship- Chief Intern Detroit Osteopathic Hospital Highland Park Michigan APPOINTMENTS 2010-Present 2010-Present 2009-Present Program Directors Committee Finance Committee Chair EEC Representative In-Training Exam Committee 2004-Present Dermatology Residency Program Director Oakwood Hospital Dearborn, Michigan

2 2004-Present Clinical Professor of Dermatology University of Des Moines 1999 Clinical Advisory Board Member Novartis Pharmaceuticals 1999-Present Clinical Professor- Dermatology Des Moines University College of Medicine CURRENT POSITIONS 2010-Present 2007-Present 1994-Present Founder and CEO - Bedside Dermatology Warren, Michigan Founder, CEO, and Medical Director Skin Perfection Southfield, Michigan Founder, CEO, and Medical Director - Grekin Skin Institute Wyandotte, Michigan Present Founder and Medical Director- Skin Rejuvenation Institute Warren, Michigan PROFESSIONAL SOCIETIES POST GRADUATE COURSES 2010 GCP/CITI Certified American Society of Dermatologic Surgery American Academy of Dermatology Society of International Hair Restoration Surgery American Geriatric Society International Society of Cosmetic Laser Surgery 1997 International Aging Skin Symposium 1997 Wound Healing Agents- Henry Ford Hospital 1996 Cook County Intensive Review of Dermatology 1995 University of California at San Francisco Department of Dermatology Facial Rejuvenation Symposium

3 1993 Cutaneous Surgery and Superficial Anatomy Scripts Institute La Jolla, California PUBLICATIONS Efficacy and Safety of Once-Daily Dapsone Gel, 7.5% for Treatment of Adolescents and Adults With Acne Vulgaris: First of Two Identically Designed, Large, Multicenter, Randomized, Vehicle-controlled Journal of Drugs in Dermatology. Jones TM, Jarratt MT, Mendez-moguel I, Paz N, Grekin SK, et al. A randomized, multicenter, double-blind, vehicle-controlled study evaluating the efficacy and safety of luliconazole cream 1% once daily for 7 days in patients aged 12 years with tinea cruris. J Drugs Dermatol. 2014;13(1):32-8. Menter A, Gold LS, Bukhalo M, Grekin S, et al. Calcipotriene plus betamethasone dipropionate topical suspension for the treatment of mild to moderate psoriasis vulgaris on the body: a randomized, double-blind, vehicle-controlled trial. J Drugs Dermatol. 2013;12(1):92-8. Saitta P, Cook CE, Messina JL, Brancaccio R, Wu BC, Grekin SK, Holland J. Is there a true concern regarding the use of hair dye and malignancy development?: a review of the epidemiological evidence relating personal hair dye use to the risk of malignancy. J Clin Aesthet Dermatol. 2013;6(1): Bethea W, Desmond B, Grekin S. Hyperpigmentation in a 51-year-old Caucasian Female. Journal of the. 2013;26: Bird M, Centilli M, Grekin S. Klippel-Trénaunay Syndrome: A case report and review of the literature. Journal of the. 2013;25: Glogau RG, Bank D, Brandt F, Cox SE, Donofrio L, Dover J, Grekin S, et al. A randomized, evaluator-blinded, controlled study of the effectiveness and safety of small gel particle hyaluronic acid for lip augmentation. Dermatol Surg. 2012;38(7 Pt 2): Child D, Aanderud P, Grekin S. A Suspicious Lesion Arising in a 28-Year-Old Female After Administration of Melanotan II. Journal of the American Osteopathic College of Dermatology. 2012;24:33. Schammel L, Grekin S. Autoimmune Progesterone Dermatitis. Journal of the American Osteopathic College of Dermatology. 2012;23:34-35.

4 Bruner M, Grekin S, Saitta P, Centilli M, Carter B. Nodular Amyloidosis: A Case Report. Journal of the. 2012;22: Aanderud P, Miner B, Grekin S. Verrucous Hemangioma: Classification and Treatment Options Addressed. Journal of the. 2012;22: Saitta P, Grekin SK. A Four-question Approach to Determining the Impact of Acne Treatment on Quality of Life. J Clin Aesthet Dermatol. 2012;5(3):51-7. Saitta P, Keehan P, Yousif J, Way BV, Grekin S, Brancaccio R. An update on the presence of psychiatric comorbidities in acne patients, Part 2: Depression, anxiety, and suicide. Cutis. 2011;88(2):92-7. Saitta P, Keehan P, Yousif J, Way BV, Grekin S, Brancaccio R. An update on the presence of psychiatric comorbidities in acne patients, part 1: overview of prevalence. Cutis. 2011;88(1): Saitta P, Cohen DE, Rigel D, Grekin SK, Brancaccio R. The frequency of self-skin examination and full body skin examination in dermatologists. J Clin Aesthet Dermatol. 2011;4(6):20-4. Feser C, Bethea W, Grekin S. Brooke-Spiegler Syndrome: A Case Report. Journal of the. 2011;21: Bruner M, Garelik J, Baze M, Grekin S. Dermatitis Herpetiformis: A Case Report and Discussion. Journal of the. 2011;20: Brooks C, Miner B, Saitta P, Grekin S. A Case of Calciphylaxis and Review of the Literature. Journal of the. 2011;19: Widgerow AD, Grekin SK. Effecting skin renewal: a multifaceted approach. J Cosmet Dermatol. 2011;10(2): Schammel L, Grekin S. Rheumatoid Neutrophilic Dermatitis. Journal of the American Osteopathic College of Dermatology. 2010;18:55. Yousif J, Saitta P, Grekin S, Lloyd J. Allergic Contact Dermatitis to Red Tattoo Dye. Journal of the. 2010;17: Anderson R, Baze M, Rabah R, Grekin S. Diagnostic and Therapeutic Dilemmas in an NF-1 Patient. Journal of the. 2010;17: Anderson R, Athalye L, Grekin S. Linear Papular Erythema in a One-Year-Old Male. Journal of the. 2009;14(1):47-49.

5 Legacy M, Anderson R, Schwimer CJ, Grekin S. Eruptive Collegenoma in a 50-year-old White Female. Journal of the. 2009;13(1):8-10. Aanderud P, Hansen D, Carlson RM, Grekin SK. En Coup de Sabre: A Case Report and Discussion. Journal of the. 2008;12(1): Verral SC, Grekin SK. Treatment of Psoriasis with a Vascular Endothelial Growth Factor Inhibitor. Journal of the. 2008;10(1):36-41 Higgins H, Grekin S, Whitworth MW. Acrodermatitis Continua Following Surgical Trauma: A Case Report. Journal of the. 2008;10(1):9-11. Hansen D, Grekin S, Collier D, Richey JD. A Woman With Gradually Spreading Telangiectasias. Journal of the. 2008;10(1): Kimball AB, Jackson JM, Sobell JM, Boh EE, Grekin S, et al. Reductions in healthcare resource utilization in psoriatic arthritis patients receiving etanercept therapy: results from the educate trial. J Drugs Dermatol. 2007;6(3): Whitworth MW, Garfield MK, Pui JC, Grekin SK. Pseudoxanthoma Elasticum and Pregnancy: A Case Report and Review of the Literature. Journal of the American Osteopathic College of Dermatology. 2007;8(2): Miner BL, Grekin S, Wilson WPD. A Case of Rapidly Progressive Benign Lymphangioendothelioma. Journal of the. 2007;8(1): Verral SC, Anderson RB, Grekin SK. Osteopathic Manipulation in Dermatology. Journal of the. 2006;7(1): Hansen DJ, Grekin SK. Dermatological Applications of Negative Pressure Wound Therapy. Journal of the. 2006;5(1): Dhawan SS, Nanda VS, Grekin S, Rabinovitz HS. Apocrine adenocarcinoma: case report and review of the literature. J Dermatol Surg Oncol. 1990;16(5):

6 RESEARCH PROJECTS Long Term Effects of Live Yeast Cell Derivative on Dermal Collagen Production The Dermatologic Consequences of the Current Trend in Over the Counter Anti-Aging Products The Effects of Combinations of Natural Enzymes and Live Yeast Cell Derivatives on Aging Skin Rapid Healing of Post Laser Patients with Topical Live Yeast Cell Derivative CLINICAL TRIAL EXPERIENCE 2011-present Anterios Acne Rosetta Rosacea Study Medicis SPHAL Lip Augmentation Medicis Tinea Cruris Study Medicis Tinea Pedis Study LEO Body Psoriasis Study LEO Scalp and Body Psoriasis Study Symbio Acne Study LEO AK Study Galderma Papulopustular Rosacea Intendis Psoriasis Kythera Double Chin Study Medicis Lip Augmentation LEO Psoriasis Phase 2 Study Intendis Papulopustular Rosacea Intendis Rosacea LEO Psoriasis Tolmar Acne Galderma Rosacea Anterios Hyperhidrosis Anterios Hyperhidrosis 2 Siefel Psoriasis Intendis Psoriasis Galderma Acne Galderma Erythema Allergan Latisse Intendis Atopic Dermatitis Galderma Filler Medicis Filler

7 Actavis Acne Coherus Psoriasis HedgePath BCCNS Valeant Psoriasis Neothetics abdominal bulge Mimetica Acne Galderma Acne Innovaderm Atopic dermatitis Galderma Rosacea Tolmar Rosacea Tolmar Tinea Cutanea Rosacea Merck Psoriasis Maruho Psoriasis Allergan Erythema Allergan Acne Tigercat Pruritis Study Valeant Acne Promius Psoriasis G&E Herbal AK 2009/2010 Intendis - Rosacea Stiefel Laboratories Acne Study Medicis Filler Study Orca Rosacea Study Basilea Pharmaceutica Hand Eczema Stiefel Laboratories Split Face Acne Study Galderma Acne Galderma Filler LEO Psoriasis Stiefel Psoriasis Allergan Acne Psolar Registry Anterios Hyperhidrosis Intendis Atopic Dermatitis Oregon Aesthetic Technologies Acne 2008 Stiegel Laboratories Acne Study Kythera Biopharmeceuticals Lipoma Study CollaGenex/Galderma Pharmaceuticals Psoriasis Study 2007 Stiefel Laboratories Duac in combination with Retin-A-Micro compared to Ziana CollaGenex Pharmaceuticals Rosacea Trial

8 2006 CollaGenex Pharmaceuticals Rosacea Study Onychomycosis Study with Clove Solution Inamed Aesthetics Hylaform Study (Line filler for nasolabial folds in skin types IV-VI) Connectics Evoclin topical antibiotic foam for chest and back acne Genentech Response Study (Raptiva/biologics) 2005 Novartis Elidel PEER trial (atopic dermatitis study) Heimat Laboratories, Ltd. Super Maco trial (oral supplement for treatment of Psorasis) Galderma MORE Trial (acne study) AMGEN Inc. - EASE Psoriasis Phase IV Clinical Trial Researching additional indications for Enbrel (biologic) Heimat Ltd. Inc. - Investigative Phase III Clinical Trial Researching a topical skin cancer agent AMGEN Inc. EDUCATE Psoriatic Arthritis Phase IV Clinical Trial, Researching alternate dosing regimen for Enbrel (biologic) BIOGEN Amevive (biologic) studied for an additional indication of alopecia areata ABSOLUTE AMENITIES Hair retardant study Laboratories Sunscreen study, investigating a plant based sunscreen additive for photoprotective qualities LECTURES 2014 Practice Management Tips International Dermatology Education Foundation Novi, MI 2014 Future of Dermatology Practice Dallas, TX 2013 Office Dermatology for the Primary Care Physician Michigan Association of Osteopathic Family Physicians Acme, Michigan 2012 Cosmeceuticals Orlando, Florida

9 2009 Medicis Clinical Lecture- New Frontiers in Acne Treatment 2008 Clinical Lecturer for Galderma Laboratories on Cosmetic Uses of Novel Topical Anesthetics Clinical Lectures in Dermatology Des Moines University Clinical Lecturer Collagenex Pharmaceuticals 1996 Efficacy of combinations of Trichloracetic Acids and Glycolic Acid in the Treatment of the Aging Face American Academy of Osteopathic Dermatology Las Vegas, Nevada 1995 Efficacy of combinations of Trichloracetic And Glycolic Acid in the Treatment of Facial Acne American Academy of Dermatology Washington, D.C Skin and Skin Structure Infections American Academy of Family Practice Chicago, Illinois 1993 Facial Rejuvenation utilizing combinations of Trichloracetic Acids and Glycolic Acid Society of Plastic and Reconstructive Surgeons of Quebec Quebec, Canada 1993 Hyperlipidemia and the Skin American College of General Practice Boston, Massachusetts