(2) A response is caused when information in the nervous system reaches an effector. the response each type of effector makes.

Transcription

1 1 This question is about the nervous system. (a) Describe the function of receptors in the skin. (b) A response is caused when information in the nervous system reaches an effector. (i) There are two different types of effector. Complete the table to show: the two different types of effector the response each type of effector makes. (4) (ii) Some effectors help to control body temperature. Give one reason why it is important to control body temperature. (Total 7 marks) Page 1 of 15

2 2 People with Type 1 diabetes cannot control the concentration of glucose in their blood. This is because they do not produce the hormone insulin. The same concentration and volume of glucose solution is given to two people. Person with Type 1 diabetes. Person without Type 1 diabetes. Figure 1 shows how the blood glucose concentration of these people changes after they each drink a glucose solution. Figure 1 (a) The blood glucose concentration increases at a faster rate in the person with diabetes compared to the person without diabetes. Calculate how much faster the rate of increase in blood glucose concentration is in the person with diabetes. Give the rate of increase for the first 30 minutes after drinking the glucose solution. Give your answer in units / h. Page 2 of 15

3 ... Units / h (b) The blood glucose concentration of the person without diabetes starts to change 30 minutes after drinking the glucose solution. Explain why the blood glucose concentration changes. Page 3 of 15

4 (c) People with diabetes should try to keep their blood glucose concentration within the same range as a person without diabetes. Most people with Type 1 diabetes regularly check their blood glucose concentration using a meter, as shown in Figure 2. The meter reading is used to estimate how much insulin they need to inject. Figure 2 Vincente Barcel/Hemera/Thinkstock Figure 3 shows a new system. It is connected to the person all the time. Figure 3 The new system: gives better control of blood glucose concentration reduces the number of times the glucose concentration falls too low. Evaluate the two systems as methods for controlling blood glucose concentrations for people with Type 1 diabetes. Give a justified conclusion to your evaluation. Page 4 of 15

5 (4) (d) How does the body respond if slightly too much insulin is injected into the body. (5) (Total 13 marks) 3 Blood sugar levels in the body are controlled by insulin. (a) How does insulin travel around the body? Page 5 of 15

6 (b) The table below shows the blood sugar levels for two people after eating a meal. Time after eating in hours Blood sugar levels in mg per 100 cm 3 of blood Person A Person B Use data from the table above to complete the graph in the figure below. Plot the points for person A. The first two points have been plotted for you. Draw a line through all the points. (3) (c) How long after the meal is person B s insulin production at its peak? Page 6 of 15

7 (d) What is the greatest decrease in the blood sugar level of person B in an hour? Decrease =... mg per 100 cm 3 (e) Estimate how long after eating the meal it will take for person B s blood sugar level to return to the level before the meal. Show your working on the figure above. (Total 9 marks) 4 The diagram shows the position of two glands, A and B, in a woman. (a) (i) Name glands A and B. A... B... Page 7 of 15

8 (ii) Gland A produces the hormone Follicle Stimulating Hormone (FSH). FSH controls changes in gland B. How does FSH move from gland A to gland B? (b) (i) A woman is not able to become pregnant. The woman does not produce mature eggs. The woman decides to have In Vitro Fertilisation (IVF) treatment. Which two hormones will help the woman produce and release mature eggs? Tick ( ) one box. FSH and Luteinising Hormone (LH) FSH and oestrogen Luteinising Hormone (LH) and oestrogen (ii) Giving these hormones to the woman helps her to produce several mature eggs. Doctors collect the mature eggs from the woman in an operation. Describe how the mature eggs are used in IVF treatment so that the woman may become pregnant. (3) Page 8 of 15

9 (iii) IVF clinics have been set a target to reduce multiple births. At least 76% of IVF treatments should result in single babies and a maximum of 24% of treatments should result in multiple births. Suggest one reason why the clinics have been set this target to reduce multiple births. (c) Two clinics, R and S, used IVF treatment on women in Doctors at each clinic used the results of the treatments to predict the success rate of treatments in The table shows the information. Total number of IVF treatments in 2007 Number of IVF treatments resulting in pregnancy in 2007 Predicted percentage success rate in 2008 Clinic R Clinic S (i) Compare the success rates of the two clinics in (ii) The range of the predicted success rate in 2008 for clinic R is much smaller than the range of the predicted success rate for clinic S. Suggest why. (Total 11 marks) Page 9 of 15

10 5 Type 1 diabetes develops when the body does not produce enough insulin. (a) Which organ produces insulin? (b) One treatment for diabetes is to inject insulin. The table gives the properties of four different types of insulin, A, B, C and D. Type of insulin Time taken for the insulin to begin to work in minutes Time taken for insulin to reach maximum concentration in the blood in minutes Time when insulin is no longer effective in hours A B C D (i) Some people with diabetes need to inject insulin just before a meal to stop a big increase in blood sugar concentration. Which type of insulin, A, B, C or D, should these people with diabetes inject just before a meal?... Give the reason for your answer. Page 10 of 15

11 (ii) A person with diabetes is told to inject type B insulin immediately after breakfast at The person with diabetes is told to then inject a second type of insulin at lunchtime at The second type of insulin should keep the blood sugar level under control for the rest of the 24 hours. Which type of insulin, A, C or D, should this person with diabetes inject at lunchtime?... Give the reason for your answer. (iii) Apart from injecting insulin, give one other way in which Type 1 diabetes can be controlled. (Total 6 marks) 6 Our bodies control the concentration of glucose in the blood. Draw a ring around the correct answer to complete each sentence. (a) The concentration of glucose in the blood is controlled by a carbohydrase. hormone called insulin. protease. intestine. (b) This hormone is produced by the stomach. pancreas. Page 11 of 15

12 (c) If the body does not produce enough of this hormone, diabetes. the person develops cystic fibrosis. Huntington s disease. (Total 3 marks) 7 The diagram shows how three hormones, FSH, LH and oestrogen, work together in a woman s body. (a) Name the part of the brain labelled X.... Page 12 of 15

13 (b) Use information from the diagram and your own knowledge to explain why some oral contraceptive pills contain oestrogen (3) (Total 4 marks) 8 Hormones are used in contraceptive pills. (a) Explain how a contraceptive pill works Page 13 of 15

14 (b) Read the information about the trialling of the first contraceptive pill. The Pill was developed by a team of scientists led by Gregory Pincus. The team needed to carry out large scale trials on humans. In the summer of 1955, Pincus visited the island of Puerto Rico. Puerto Rico is one of the most densely populated areas in the world. Officials supported birth control as a form of population control. Pincus knew that if he could demonstrate that the poor, uneducated women of Puerto Rico could use the pill correctly then so could women anywhere in the world. The scientists selected a pill with a high dose of hormones to ensure that no pregnancies would occur while test subjects were taking the drug. The Pill was found to be 100% effective when taken properly. But 17% of the women in the study complained of side effects. Pincus ignored these side effects. The women in the trial had been told only that they were taking a drug that prevented pregnancy. They had not been told that the Pill was experimental or that there was a chance of dangerous side effects. Evaluate the methods used by Pincus in trialling the contraceptive pill (5) (Total 7 marks) Page 14 of 15

15 9 The human body produces many hormones. (a) (i) What is a hormone? (ii) Name an organ that produces a hormone. (iii) How are hormones transported to their target organs? (b) Describe how the hormones FSH, oestrogen and LH are involved in the control of the menstrual cycle (3) (Total 6 marks) Page 15 of 15