2012 Year In Review In Review. Number of Patients on WaitList as of Number Of Transplants Year. Number Of Patients

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1 Number Of Patients Number Of Transplants In Review In Review Kidney Kidney Pancreas Pancreas Liver Heart Number of Patients on WaitList as of.. Kidney Kidney Pancreas Liver Heart

2 Number of Donors Number of Donors Organ Donor Statistics Atlantic Canada DBD Donors by Reporting Province of Death 9 9 NS PE NB NL Atlantic Canada DBD Donors Per Million by Province 9 9 NS PE NB NL Atl Can * DBD - Donation After Brain Death

3 Number of Donors Number of Donors DBD Donors by Age 9 9 <= s and s and s > s DBD Donors by Age (in percentage) % 9% % % % % % % % % %.%.%.%.%.9%.%.9%.%.9%.9%.%.%.%.%.% 9.%.%.%.% 9.%.9%.%.9%.% 9 <= s and s and s > s

4 Number of Donors DBD Donors by Cause of Death 9 MVA (Motor Vehical Accident) Head Injury (Trauma) Suicide Cardio Vascular Anoxia/Hypoxia Spontaneous Intracranial Hemorrhage Cerebral Vascular Accident Other DBD Donors by Cause Of Death (-) 9.9%.%.9%.%.% 9.%.9% MVA (Motor Vehical Accident) Head Injury (Trauma) Suicide Cardio Vascular Anoxia/Hypoxia Spontaneous Intracranial Hemorrhage Cerebral Vascular Accident Other

5 Number of Donors Number of Donors DBD Donors by Blood Type 9 9 A B O AB DBD Donors by Gender Male Female

6 Number of Donors DBD Donors Organs Exported / Imported (-) Montreal Quebec MORE Ottawa MORE London MORE Toronto MORE Hamilton MORE Calgary MORE Edmonton Manitoba British Columbia USA Exported Liver Organs Imported Liver Organs Exp Heart Organs Imp Heart Organs

7 Number of Exports Number of Imports Liver Allocation (Import for High Status) /F F /F F /F F /F F /F F /F F 9 Montreal Quebec MORE Ottawa MORE London MORE Toronto MORE Hamilton MORE Calgary MORE Edmonton Manitoba British Columbia USA * See Appendix A for Medical Status Description Liver Allocation (Export for High Status) /F F /F F /F F /F F /F F /F F 9 Montreal Quebec MORE Ottawa MORE London MORE Toronto MORE Hamilton MORE Calgary MORE Edmonton Manitoba British Columbia USA * See Appendix A for Medical Status Description

8 Number of Exports Number of Imports Heart Allocation (Import for High Status) Status Status Status Status Status Status 9 Montreal Quebec MORE Ottawa MORE London MORE Toronto MORE Hamilton MORE Kingston MORE Calgary MORE Edmonton Manitoba British Columbia USA * See Appendix A for Medical Status Description Heart Allocation (Export for High Status) Status Status Status Status Status Status 9 Montreal Quebec MORE Ottawa MORE London MORE Toronto MORE Hamilton MORE Kingston MORE Calgary MORE Edmonton Manitoba British Columbia USA * See Appendix A for Medical Status Description

9 Number of Donors Renal Transplants Live vs DBD (n=) Live (n=) DBD (n=) DBD (n=) % Live (n=) %

10 Number Of Transplants Kidney / Kidney Pancreas Transplant Services Kidney / Kidney Pancreas Transplants Performed for Atlantic Canada Recipients 9 9 Kidney KP Atlantic Canada Kidney / Kidney PancreasTransplant Recipients by Province NS PE NB NL DBD Donor Live Related Donor

11 Number Of Transplants Kidney / Kidney Pancreas Transplants By Age At Transplant K KP K KP K KP K KP K KP K KP K KP K KP K KP > And <= s > And <= s > And <= s > Kidney / Kidney Pancreas Transplants by Primary Diagnosis Groups 9 Kidney Other (Chronic renal failure, tumors..) Congenital/Hereditary Diseases Diabetes Polycystic Kidneys Glomerulonephritis/Autoimmune Diseases Nephropathy - Drug Induced Renal Vascular Disease Pyelonephritis/Interstitial Nephritis

12 Kidney / Kidney Pancreas Transplants Diabetes Type I, Type II and Non-Diabetic Type I Type II Non-Diabetic Kidney / Kidney Pancreas Transplants By Gender Male Female

13 Kidney / Kidney Pancreas Transplants by Dialysis Types 9 9 CAPD CCPD Home Hemodialysis Hospital Hemodialysis Satellite Hemodialysis Preemptive * CAPD - Continuous Ambulatory Peritoneal Dialysis * CCPD - Chronic Cyclic Peritoneal Dialysis

14 Number Of Deaths Kidney Wait List Deaths (Including Workups) in Atlantic Canada 9 9 Kidney / Kidney Pancreas Transplants By Blood Type K KP K KP K KP K KP K KP K KP K KP K KP K KP K KP K KP 9 K KP 9 K KP K KP 9 A B O AB 9

15 Kidney / Kidney Pancreas Deceased Donor Transplants by HLA Matching 9 A, B, DR Mismatch B, DR Mismatch DR Mismatch A, B, DR Mismatch B DR Mismatch All other mismatches Wait Time Kidney / Kidney Pancreas DBD Donor Transplants (n=) by HLA Matching vs Wait Time (n=) % (n=) % HLA Matching Wait Time

16 Kidney Pancreas Transplants 9 9 Kidney Pancreas Transplants By Province 9 NS PE NB NL

17 Number Of Transplants Liver Transplant Services Liver Transplants Performed for Atlantic Canada Recipients 9 Liver Transplants By Province NS PE NB NL

18 Number Of Transplants Liver Transplants By Gender 9 Male Female Liver Transplants By Age At Transplant 9 > And <= s >= And <= s >= And <= s >

19 Number Of Transplants Liver Transplants By Medical Status At Transplant 9 - T - F - F Indications for Liver Transplants by Primary Diagnosis 9 Cirrhosis - Alcohol Cirrhosis - Alcohol Hepatocellular Carcinoma Viral Hepatitas Autoimmune Disease Fatty Liver Disease Others

20 Liver Patients MELD Score At Transplant Liver Patients MELD Score At Transplant >= And <= >= And <=9 >= * See Appendix A for MELD Score Description Liver Patient Wait List Deaths % 9% Percentage Deceased Percentage Live

21 Medical Status Appendix A Liver Medical Status Description At Home. T At Home with a liver tumor. In Hospital with stable condition. In ICU or equivalent care facility but not on mechanical support with either: (a) creatinine > umol/l and / or rising by > umol/l per day, or (b) grade or encephalopathy. F In ICU or equivalent care facility due to fulminant liver failure but not on mechanical support In ICU requiring mechanical ventilation. Death is considered imminent without liver transplantation. In ICU requiring mechanical ventilation due to fulminant liver failure including primary graft non-function. F Death is considered imminent without liver transplantation MELD Score Description The Model for End-Stage Liver Disease is a numerical scale that is currently used for liver allocation. The MELD score is based on a patient's risk of dying while waiting for a liver transplant, and is based on objective and verifiable medical data. The MELD score calculation uses: Serum Creatinine (mg/dl) ** Bilirubin (mg/dl) INR The MELD score is calculated using the following formula: MELD Score =.9 x Loge(creatinine mg/dl) +. x Loge(billirubin mg/gl) +.xloge(inr) +. x Multiply the score by and round to the nearest whole number. Disclaimer: Historical data contained in this report is subject to change

22 Number Of Transplants Cardiac Transplant Services Heart Transplants Performed for Atlantic Canada Recipients 9 9 Heart Transplants By Province 9 NS PE NB NL

23 Number Of Transplants Heart Transplants By Gender 9 9 Male Female Heart Transplants By Age At Transplant 9 > And <= s > And <= s > And <= s >=

24 Number Of Transplants Heart Transplants by Primary Diagnosis 9 Valvular Heart Disease: Severe Lv Dysfunction Ischemic Heart Disease Dilated Cardiomyopathy (Viral ) Ischemic Cardiomyopathy Hypertrophic Cardiomyopathy Arrhythmogenic Right Ventricle Dysplasia End Stage Biventricular Heart Failure Cardiogenic Shock Congenital Heart Disease Acute Myocardial Infarction Idiopathic Cardiomyopathy Restrictive Cardiomyopathy Congestive Heart Failure Coronary Artery Disease Heart Transplants By Medical Status At Transplant 9 A - B * See Appendix B for Medical Status Description

25 Heart Transplants By Blood Type 9 A B O AB

26 Appendix B Medical Status Heart Medical Status Description At Home. In Hospital. A VAD or Intravenous Inotropes on ward or at home. B ICU - Continuous infustion of intravenous inotropes (high dose of one or more inotropes). ICU - Mechanical Ventilatory or Circulatory Support. Disclaimer: Historical data contained in this report is subject to change

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