Ambulatory ph Monitoring

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1 Patient: Sample, Sample Gender: Male Physician: Physician Birth Date: Technician: Operator Weight: Referring Referring Physician Physician: Height: Medication: Off Indications: Study Date: 07/06/2009 ph Analysis Thresholds Channel 1 Threshold, ph 4.0 Study Durations(HH:MM) Time Total 44:02 Upright 27:36 Supine 16:26 Post-prandial 11:49 Sample, Sample, , Study Date: 07/06/ of 10

2 Acid Reflux Analysis Channel 1 Total Time spent in reflux (HH:MM) 06:05 Number of refluxes 52 Number of refluxes per hour 1.3 % Time spent in reflux 14.8 Number of long refluxes 19 Longest reflux (HH:MM) 00:48 Upright Time spent in reflux (HH:MM) 01:49 Number of refluxes 28 Number of refluxes per hour 1.1 % Time spent in reflux 7.0 Number of long refluxes 7 Longest reflux (HH:MM) 00:20 Supine Time spent in reflux (HH:MM) 04:17 Number of refluxes 24 Number of refluxes per hour 1.6 % Time spent in reflux 27.9 Number of long refluxes 12 Longest reflux (HH:MM) 00:48 Post-prandial Time spent in reflux (HH:MM) 00:36 Number of refluxes 5 Number of refluxes per hour 0.4 % Time spent in reflux 5.1 Number of long refluxes 1 Longest reflux (HH:MM) 00:33 DeMeester Score Channel 1 Normal (95th percentile) 60.1 Symptom Analysis (ph) Cough No. of symptoms analyzed 148 Channel 1 No. of symptoms related to reflux 9 No. of symptoms not related to Reflux 139 No. of reflux periods 52 Symptom index for reflux (SI) 6.1 Symptom sensitivity index (SSI) 17.3 Symptom association prob. (SAP)* 0.0 * Probability that symptom and reflux are not associated solely by chance, (>95% is significant) Sample, Sample, , Study Date: 07/06/ of 10

3 Day 1 ph Analysis Thresholds Channel 1 Threshold, ph 4.0 Study Durations(HH:MM) Time Total 24:00 Upright 15:04 Supine 08:56 Post-prandial 05:51 Acid Reflux Analysis Channel 1 Total Time spent in reflux (HH:MM) 01:36 Number of refluxes 14 Number of refluxes per hour 0.6 % Time spent in reflux 7.2 Number of long refluxes 5 Longest reflux (HH:MM) 00:31 Upright Time spent in reflux (HH:MM) 00:04 Number of refluxes 4 Number of refluxes per hour 0.3 % Time spent in reflux 0.5 Number of long refluxes 0 Longest reflux (HH:MM) 00:02 Supine Time spent in reflux (HH:MM) 01:32 Number of refluxes 10 Number of refluxes per hour 1.2 % Time spent in reflux 18.3 Number of long refluxes 5 Longest reflux (HH:MM) 00:31 Post-prandial Time spent in reflux (HH:MM) 00:03 Number of refluxes 2 Number of refluxes per hour 0.3 % Time spent in reflux 0.9 Number of long refluxes 0 Longest reflux (HH:MM) 00:02 DeMeester Score Channel 1 Normal (95th percentile) 33.8 Symptom Analysis (ph) Cough No. of symptoms analyzed 114 Channel 1 No. of symptoms related to reflux 3 No. of symptoms not related to Reflux 111 No. of reflux periods 14 Symptom index for reflux (SI) 2.6 Symptom sensitivity index (SSI) 21.4 Symptom association prob. (SAP)* 0.0 * Probability that symptom and reflux are not associated solely by chance, (>95% is significant) Sample, Sample, , Study Date: 07/06/ of 10

4 Day 2 ph Analysis Thresholds Channel 1 Threshold, ph 4.0 Study Durations(HH:MM) Time Total 20:02 Upright 12:32 Supine 07:30 Post-prandial 05:58 Acid Reflux Analysis Channel 1 Total Time spent in reflux (HH:MM) 04:29 Number of refluxes 38 Number of refluxes per hour 2.0 % Time spent in reflux 23.8 Number of long refluxes 14 Longest reflux (HH:MM) 00:48 Upright Time spent in reflux (HH:MM) 01:44 Number of refluxes 24 Number of refluxes per hour 2.0 % Time spent in reflux 14.7 Number of long refluxes 7 Longest reflux (HH:MM) 00:20 Supine Time spent in reflux (HH:MM) 02:45 Number of refluxes 14 Number of refluxes per hour 2.0 % Time spent in reflux 39.4 Number of long refluxes 7 Longest reflux (HH:MM) 00:48 Post-prandial Time spent in reflux (HH:MM) 00:33 Number of refluxes 3 Number of refluxes per hour 0.5 % Time spent in reflux 9.3 Number of long refluxes 1 Longest reflux (HH:MM) 00:33 DeMeester Score Channel 1 Normal (95th percentile) 88.5 Symptom Analysis (ph) Cough No. of symptoms analyzed 34 Channel 1 No. of symptoms related to reflux 6 No. of symptoms not related to Reflux 28 No. of reflux periods 38 Symptom index for reflux (SI) 17.6 Symptom sensitivity index (SSI) 15.8 Symptom association prob. (SAP)* 0.0 * Probability that symptom and reflux are not associated solely by chance, (>95% is significant) Procedure Description Bravo 48 hour wireless reflux monitoring Interpretation / Findings Dr. Sample Sample, Sample, , Study Date: 07/06/ of 10

5 Diary Sample, Sample, , Study Date: 07/06/ of 10

6 Event Day Begin End Duration Note Meal 1 11:00:04 11:10:04 00:10 Cough 1 11:11:52 Cough 1 11:14:40 Cough 1 11:15:28 Cough 1 11:16:04 Cough 1 11:28:04 Cough 1 11:59:28 Cough 1 12:00:16 Cough 1 12:12:40 Cough 1 12:13:28 Cough 1 12:20:28 Cough 1 12:24:52 Cough 1 12:31:28 Cough 1 12:32:28 Cough 1 12:35:52 Cough 1 12:39:52 Cough 1 12:53:28 Cough 1 12:54:04 Cough 1 13:17:52 Cough 1 13:30:52 Cough 1 13:40:52 Cough 1 13:45:40 Cough 1 13:46:28 Cough 1 13:48:28 Cough 1 13:52:04 Cough 1 13:53:04 Cough 1 13:55:04 Cough 1 14:00:04 Cough 1 15:15:28 Cough 1 15:16:04 Meal 1 15:19:04 15:44:04 00:25 Cough 1 15:45:52 Cough 1 15:47:16 Cough 1 15:52:28 Cough 1 15:57:52 Cough 1 16:04:40 Cough 1 16:13:16 Cough 1 16:19:28 Cough 1 16:25:40 Cough 1 16:32:28 Cough 1 16:33:16 Cough 1 16:34:28 Cough 1 16:39:04 Cough 1 16:44:28 Cough 1 16:46:40 Cough 1 16:49:16 Cough 1 16:56:16 Cough 1 17:07:28 Cough 1 17:09:52 Cough 1 17:14:28 Cough 1 17:16:40 Cough 1 17:17:16 Cough 1 17:22:28 Cough 1 17:24:40 Cough 1 17:32:04 Cough 1 17:42:28 Cough 1 17:48:04 Cough 1 17:48:28 Cough 1 18:15:40 Cough 1 18:18:04 Cough 1 18:27:40 Cough 1 18:35:40 Cough 1 18:41:28 Supine 1 18:42:04 03:38:04 08:56 Sample, Sample, , Study Date: 07/06/ of 10

7 Cough 1 18:46:28 Cough 1 19:00:52 Cough 1 19:05:04 Cough 1 19:28:52 Cough 1 20:23:40 Cough 1 21:11:52 Cough 1 21:49:40 Cough 1 22:01:40 Cough 1 22:42:52 Cough 1 22:59:28 Cough 1 23:49:40 Cough 2 00:38:28 Cough 2 01:51:40 Cough 2 03:40:28 Cough 2 03:41:52 Cough 2 03:47:52 Cough 2 03:49:40 Cough 2 03:50:28 Cough 2 03:55:52 Cough 2 03:58:04 Cough 2 03:59:28 Cough 2 04:02:40 Cough 2 04:18:04 Cough 2 04:46:28 Cough 2 04:47:04 Cough 2 05:00:28 Cough 2 05:05:40 Cough 2 05:29:16 Cough 2 05:33:40 Cough 2 05:47:52 Cough 2 06:00:04 Meal 2 06:27:04 06:31:04 00:04 Cough 2 06:31:40 Cough 2 06:32:28 Cough 2 06:33:16 Cough 2 07:08:28 Cough 2 07:08:52 Cough 2 07:10:28 Cough 2 07:23:28 Cough 2 07:32:16 Cough 2 07:35:16 Cough 2 07:36:04 Cough 2 07:49:04 Cough 2 07:58:16 Cough 2 08:08:16 Cough 2 08:31:04 Cough 2 08:36:16 Cough 2 08:36:52 Cough 2 08:47:16 Cough 2 09:22:28 Cough 2 09:50:28 Cough 2 09:51:52 Cough 2 10:03:40 Cough 2 10:09:04 Cough 2 10:16:28 Meal 2 10:23:04 10:41:04 00:18 Cough 2 10:45:16 Cough 2 11:22:04 Cough 2 11:55:40 Cough 2 12:19:40 Cough 2 12:36:04 Cough 2 12:36:16 Cough 2 13:18:16 Cough 2 13:37:28 Cough 2 14:41:04 Sample, Sample, , Study Date: 07/06/ of 10

8 Cough 2 15:11:28 Meal 2 16:24:04 16:46:04 00:22 Cough 2 17:00:40 Cough 2 17:40:40 Cough 2 18:06:52 Supine 2 18:12:04 01:42:04 07:30 Cough 2 18:26:28 Cough 2 22:22:52 Cough 3 01:12:04 Cough 3 01:34:40 Cough 3 01:42:28 Cough 3 01:49:04 Cough 3 01:53:04 Cough 3 02:21:16 Cough 3 03:08:28 Cough 3 03:21:28 Cough 3 03:40:28 Cough 3 03:56:04 Cough 3 04:08:04 Cough 3 04:21:16 Meal 3 04:29:04 04:44:04 00:15 Cough 3 04:45:16 Cough 3 05:01:16 Cough 3 05:08:16 Cough 3 05:19:04 Cough 3 05:48:28 Cough 3 06:23:28 Cough 3 06:39:16 Sample, Sample, , Study Date: 07/06/ of 10

9 Sample, Sample, , Study Date: 07/06/ of 10

10 Sample, Sample, , Study Date: 07/06/ of 10

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