THE APPLICATION OF SPECT QUANTITATIVE TECHNIQUE IN CORONARY HEART DISEASE

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1 SPECT SPECT SPECT /CT SPECT PET kbq cm -3 SPECT R541.4 A DOI: /j.cnki.issn x X THE APPLICATION OF SPECT QUANTITATIVE TECHNIQUE IN CORONARY HEART DISEASE WANG Tao WANG Xiang-cheng ZHANG Guo-jian et al. The Affiliated Hospital Inner Mongolia Medical University Hohhot China Abstract Since the advent of SPECT only half quantitative analysis but with SPECT /CT image reconstruction algorithm full physical compensation technology for the emergence of attenuation and scattering photon technology have introduced similar to PET the SPECT of quantitative methods i.e. kbq cm -3. Myocardial perfusion imaging is myocardial ischemia and myocardial infarction commonly used to examine the evaluation the emergence of SPECT quantitative technology making the diagnosis of myocardial perfusion imaging for coronary heart disease in the sensitivity specificity and accuracy are improved and carries on the quantitative analysis of myocardial blood flow reserve. Key words SPECT quantitative technical coronary heart disease myocardial blood flow 78 MPI /10 99mTc /10 MIBI MPI KG0356 kjt15sf wangxuemei201010@ 163.com

2 310 Journal Of Inner Mongolia Medical University June 2018 Vol.40 No.3 PET kbq /ml N-13Ammonia O - 15Water PET 99mTC-diphosponate SPECT /CT MPI 16 3~ PET 3.6% 1.1% Vandervoort 14 SPECT 99mTc SPECT CT 4% Bailey 15 99mTC-macroaggregatwd albumin 12-1% SPECT -7% ~ +4% SPECT ±10% 12 SPECT SPECT 2 SPECT 10 r SPECT /CT 2.1 MPI 11 SPECT MPI SPECT CT MPI SPECT 85% 91% CT SPECT CZT SPECT 12 SPECT CZT SPECT SUV Duvall 16 CZT SPECT CZT SPECT 89% 66% OSEM Zeintl 13 78% Fiechter 17 3D-OSEM Hsu 11 OSEM CZT SPECT /CT Zeintl 87% 67% 92% % 83% Oldan 18 CZT SPECT SPECT SPECT /CT Prrich 19 SPECT MPI 97% MPI 96% 2.2 SPECT /CT MBF MFR SPECT /CT PET /CT

3 Bouallègue CAD MPR 80% 85% 81% FFR 89% 82% 85% MBF MFR Hsu Shiraishi MFR MPR 84.6% 100% MI 100% 80% P = 0.9 MBF MPR 1.96 ml /g /min 84.5% 0.81 MI 100% 100% 79.6% MPR P = 0.8 MBF MFR 1.5 MPR MI 1 CAD 2 86% 78% 80% 64% 76% 73% 57% 93% 84% CAD 3 3 MPR MBF 20 MBF CFR CFR CFR 200μm N Ammonia O-15Water PET CFR MPR Hsu 21 SPECT N- 13Ammonia PET MBF CRF MBF CRF 0.92 SPECT Chen 28 26mo 0.78 MBF CRF Gan a CFR 2 SPECT % CFR 36.8%CFR 10.8% 4.63 SPECT SPECT 95% 2.78 ~ 7.69 P < CFR SPECT MPR MPR 1 Fye WB. President s page cardiology and technology an

4 312 Journal Of Inner Mongolia Medical University June 2018 Vol.40 No.3 enduring and energizing partnership J. J Am Coll Cardiol recovery Attenuation And scatter correction J. J Nucl J Med Schindler TH Schelbert HR Quercioli A et al.cardiac pet imaging for the detection and monitoring of coronary artery disease and microvascular health J.JACC Cardiovasc Imaging Schelbert HR.Quantification of myocardial blood flow what is the clinical role J. Cardiol Clin Lee JM Kim CH Koo BK et al.integrated myocardial perfusion imaging diagnostics improve detection of functionally significant coronary artery stenosis by 13 N-ammonia positron emission tomography J. Circ Cardiovasc Imaging e Konerman MC Greenberg JC Kolias TJ et al.reduced myocardial flow reserve Is associated with diastolic dysfunction and decreased left atrial strain in patients with normal ejection fraction and epicardial perfusion J. J Card Fail Srivaratharajah K Coutinho T Dekemp R et al. Reduced myocardial flow in heart failure patients with preserved e- jection fraction J.Circ Heart Fail e Petretta M Storto G Pellegrino T et al.quantitative assessment of myocardial blood flow with spect J.Prog Cardiovasc Dis Ben bouallègue F Roubille F Lattuca B et al.spect myocardial perfusion reserve in patients with multivessel coronary disease correlation with angiographic findings and invasive fractional flow reserve measurements J. J Nucl Med IQ spect 21 Hsu B Hu LH Yang BH et al. Spect myocardial blood spect spect J. flow quantitation toward clinical use a comparative study Bailing hsu Fu-chung chen Tao-cheng Wu et al.quantitation of myocardial blood flow and myocardial flow reserve with 99 mtc - sestamibi dynamic spect / CT to enhance detection of coronary artery disease J. Eur J Nucl Med Mol Imaging Bailey DL Willowson KP. An evidence - based review of quantitative spect imaging and potential clinical applications J.J Nucl Med Zeintl J Vija AH Yahil A et al. Quantitative accuracy of clinical 99 mtc spect / CT using ordered - subset expectation maximization with3 - dimensional resolution 14 Vandervoort E Celler A Harrop R. Implementation of an iterative scatter correction The in uence of attenuation map quality and their effect on absolute quantitation in spect J.Phys Med Biol Willowson K Bailey DL Baldock C. Quantitative spect using CT-derived corrections J. Phys Med Biol Duvall WL Sweeny JM Croft LB et al. Reduced stress dose with rapid acquisition czt spect mpi in a non-obese clinical population comparison to coronary angiography J.J Nucl Cardiol Fiechter M Ghadri JR Kuest SM et al. Nuclear myocardial perfusion imaging with a novel cadmium-zinc -telluride detector spect /CT device first validation versus invasive coronary angiography J. Eur J Nucl Med Mol Imaging Oldan JD Shaw LK Hofmann P et al.prognostic value of the cadmium-zinc-telluride camera A comparison with a conventional anger camera J.J Nucl Cardiol Pirich C Keinrath P Barth G et al. Diagnostic accuracy and functional parameters of myocardial perfusion scintigraphy using accelerated cardiac acquisition with IQ spect technique in comparison to conventional imaging J.Q J Nucl Med Mol Imaging Schindler TH Quercioli A Valenta I et al. Quantitative assessment of myocardial blood flow clinical and research applications J. Semin Nucl Med with 13 N - ammonia pet myocardial blood flow quantitation J. Eur J Nucl Med Mol Imaging Naya M murthy VL Taqueti VR et al.preserved coronary flow reserve effectively excludes high-risk coronary artery disease on angiography J. J Nucl Med

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