Fibrinólisis y ATCp: de las guías clínicas al mundo real
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1 Fibrinólisis y ATCp: de las guías clínicas al mundo real Dr. LUIS ALBERTO URNA HERBAS, MSc. Cardiología Intervencionista y Hemodinamia Hospital San Juan de Dios INMED Intervencionismo Médico
2 DECLARACIÓN DE CONFLICTOS DE INTERÉS Sin conflictos de interés.
3 ESC/EACTS GUIDELINES ON MYOCARDIAL REVASCULARIZATION Eur Heart J Oct 1;35(37): doi: /eurheartj/ehu278. Epub 2014 Aug 29.
4 ESC/EACTS GUIDELINES ON MYOCARDIAL REVASCULARIZATION Eur Heart J Oct 1;35(37): doi: /eurheartj/ehu278. Epub 2014 Aug 29.
5 ESC/EACTS GUIDELINES ON MYOCARDIAL REVASCULARIZATION Primary PCI for myocardial reperfusion in STEMI Reperfusion therapy is indicated in all patients with time from symptom onset <12 hours duration and persistent ST- segment elevation or (presumed) new LBBB. Primary PCI is the recommended reperfusion therapy over fibrinolysis if performed by an experienced team in a timely fashion. In patients with time from symptom onset >12 hours, primary PCI is indicated in the presence of continuing ischaemia, life-threatening arrhythmias or if pain and ECG changes have been stuttering. Eur Heart J Oct 1;35(37): doi: /eurheartj/ehu278. Epub 2014 Aug 29.
6 ESC/EACTS GUIDELINES ON MYOCARDIAL REVASCULARIZATION Primary PCI for myocardial reperfusion in STEMI Primary PCI is indicated for patients with severe acute heart failure or cardiogenic shock due to STEMI independent from time delay of symptom onset. Reperfusion therapy with primary PCI should be considered in patients presenting late (12 48 hours) after symptom onset. It is recommended that primary PCI-capable centres deliver a 24- hour/7-day service and ensure for primary PCI to be performed as fast as possible and at the latest within 60 minutes of hospital arrival. Eur Heart J Oct 1;35(37): doi: /eurheartj/ehu278. Epub 2014 Aug 29.
7 ESC/EACTS GUIDELINES ON MYOCARDIAL REVASCULARIZATION Fibrinolysis Despite its frequent contraindications, limited effectiveness in inducing reperfusion, and greater associated risk of bleeding, fibrinolytic therapy preferably administered as a pre-hospital treatment remains an adjunct to mechanical revascularization if the latter cannot The incremental benefit of primary PCI over timely fibrinolysis is diminished when PCI-related delay exceeds 120 minutes, depending on patient age, duration of symptoms, and infarct location. Fibrinolysis is discussed in detail in the ESC Guidelines on STEMI. Eur Heart J Oct 1;35(37): doi: /eurheartj/ehu278. Epub 2014 Aug 29.
8 CONSENSO SAC DE IAM CON ELEVACIÓN DEL SEGMENTO ST Rev. Argent. Cardiol. Vo. 83 Supl. 4 Octubre 2015 ISSN versio n electro nica
9 CONSENSO SAC DE IAM CON ELEVACIÓN DEL SEGMENTO ST Rev. Argent. Cardiol. Vo. 83 Supl. 4 Octubre 2015 ISSN versio n electro nica
10 CONSENSO SAC DE IAM CON ELEVACIÓN DEL SEGMENTO ST Rev. Argent. Cardiol. Vo. 83 Supl. 4 Octubre 2015 ISSN versio n electro nica
11 CONSENSO SAC DE IAM CON ELEVACIÓN DEL SEGMENTO ST Recomendaciones para angioplastia primaria Rev. Argent. Cardiol. Vo. 83 Supl. 4 Octubre 2015 ISSN versio n electro nica
12 CONSENSO SAC DE IAM CON ELEVACIÓN DEL SEGMENTO ST Recomendaciones para el uso de fibrinolíticos Rev. Argent. Cardiol. Vo. 83 Supl. 4 Octubre 2015 ISSN versio n electro nica
13 CONSENSO SAC DE IAM CON ELEVACIÓN DEL SEGMENTO ST Recomendaciones para trombo lisis prehospitalaria o en centros de baja complejidad sin acceso a angioplastia primaria Rev. Argent. Cardiol. Vo. 83 Supl. 4 Octubre 2015 ISSN versio n electro nica
14 APPROPRIATE USE CRITERIA FOR CORONARY REVASCULARIZATION IN PATIENTS WITH ACS STEMI Immediate Revascularization by PCI J Am Coll Cardiol Feb 7;69(5): doi: /j.jacc Epub 2016 Dec 21.
15 APPROPRIATE USE CRITERIA FOR CORONARY REVASCULARIZATION IN PATIENTS WITH ACS STEMI Initial Treatment by Fibrinolytic Therapy J Am Coll Cardiol Feb 7;69(5): doi: /j.jacc Epub 2016 Dec 21.
16 APPROPRIATE USE CRITERIA FOR CORONARY REVASCULARIZATION IN PATIENTS WITH ACS STEMI Revascularization of Nonculprit Artery During the Initial Hospitalization J Am Coll Cardiol Feb 7;69(5): doi: /j.jacc Epub 2016 Dec 21.
17 TREATMENT OF AMI IN WOMEN STEMI reperfusion strategies: THROMOBLYTICS PCI Circulation Mar 1;133(9): doi: /CIR Epub 2016 Jan 25
18 META-ANALYSES: COMPARISON OF PPCI AND FIBRINOLYTIC THERAPY IN STEMI Bayesian forest plot of all-cause shortterm mortality rates in RCTs Bayesian forest plot of all-cause short-term mortality rates in observational studies Circulation Jun 23;119(24): doi: /CIRCULATIONAHA Epub 2009 Jun 8.
19 ESTRATEGIAS DE REPERFUSIO N EN EL IAMCEST. VISIÓN GENERAL Y DESCRIPCIO N DE CONCEPTOS. SITUACIO N ACTUAL DE LA REPERFUSIO N FARMACOLO GICA EN ESPAN A Tipo de reperfusio n utilizado en los registros espan oles PRIAMHO II (2000) y MASCARA ( ) y el Second Euro Heart Survey on Acute Coronary Syndromes (EHS-ACS II) (2004 Rev Esp Cardiol Supl. 2009;09(C): Vol. 09 Núm.Supl.C
20 REGISTRO RENIMA Y RENIMA II: REGISTRO NACIONAL DE INFARTO DE MIOCARDIO AGUDO EN PERÚ RENIMA: Tratamiento de Intervencio n no Farmacolo gica Recibida (n = 995) RENIMA II: Distribucio n por Tratamiento e Intervencio n (n = 1609) Revista Peruana de Cardiologi a Vol. XXXiV No 2 Mayo - Agosto 2008 Miguel Reyes Rocha y cols. Revista Peruana de Cardiologi a Vol. XXXIX No 1 Enero - Abril 2013 Miguel Reyes Rocha y cols.
21 INFARTO AGUDO DE MIOCARDIO EN LA REPÚBLICA ARGENTINA. REGISTRO CONAREC XVII Infarto agudo de miocardio con supradesnivel del segmento ST. Terapia de reperfusio n ATCp Rev ARgent CARdiol 2013;81:
22 GWTG-CAD REGISTRY: TEMPORAL TRENDS IN CARE AND OUTCOMES OF PATIENTS RECEIVING FIBRINOLYTIC THERAPY COMPARED TO PPCI J Am Heart Assoc. 2016;5:e doi: /JAHA pii: e
23 TEMPORAL TRENDS OF REPERFUSION STRATEGIES AND HOSPITAL MORTALITY FOR STEMI PATIENTS IN PCI- CAPABLE HOSPITALS Reperfusion strategies for STEMI patients in Canada Can J Cardiol Apr;33(4): doi: /j.cjca Epub 2016 Dec 8.
24 IMPACTO EN LA MORTALIDAD DE DIFERENTES SISTEMAS DE ASISTENCIA EN RED PARA EL TRATAMIENTO DEL IAMCEST. LA EXPERIENCIA DE ESPAÑA Estrategias de reperfusión ATCp Rev Esp Cardiol. 2017;70: Vol. 70 Núm.03 DOI: /j.recesp
25 GWTG-CAD REGISTRY: TEMPORAL TRENDS IN CARE AND OUTCOMES OF PATIENTS RECEIVING FIBRINOLYTIC THERAPY COMPARED TO PPCI In-Hospital Outcomes Between Patients With STEMI Receiving Fibrinolysis vs PPCI J Am Heart Assoc. 2016;5:e doi: /JAHA pii: e
26 CAMI REGISTRY: THE COMPARISON OF THE OUTCOMES BETWEEN PRIMARY PCI, FIBRINOLYSIS, AND NO REPERFUSION IN PATIENTS >75 YEARS OLD WITH STEMI Clinical outcomes with different reperfusion strategies PLoS One Nov 3;11(11):e doi: /journal.pone ecollection 2016.
27 ASSOCIATION OF GUIDELINE-BASED ADMISSION TREATMENTS AND LIFE EXPECTANCY AFTER MYOCARDIAL INFARCTION IN ELDERLY MEDICARE BENEFICIARIES Years of Life Lost Associated With Increasing D2B and D2N Time J Am Coll Cardiol May 24;67(20): doi: /j.jacc
28 DIRECT ADMISSION VERSUS INTERHOSPITAL TRANSFER FOR PRIMARY PERCUTANEOUS CORONARY INTERVENTION IN ST- SEGMENT ELEVATION MYOCARDIAL INFARCTION Direct Admission and Interhospital Transfer Rates in STEMI 12-Month Mortality JACC Cardiovasc Interv Mar 13;10(5): doi: /j.jcin Epub 2017 Feb 15.
29 INTER-FACILITY TRANSFER VS. DIRECT ADMISSION OF PATIENTS WITH STEMI UNDERGOING PPCI Circ J Jul 25;80(8): doi: /circj.CJ Epub 2016 Jun 28.
30 CODI IAM: EARLY STEMI IN NON-CAPABLE PCI CENTRES: IN SITU FIBRINOLYSIS VS. PCI TRANSFER Thirty-day mortality relative to the assigned group (transfer or fibrinolysis) and delay from first medical contact-device for transfer group in tertiles Eur Heart J Apr 1;37(13): doi: /eurheartj/ehv619. Epub 2015 Nov 18.
31 IMPACT OF DOOR-TO-BALLOON TIME ON LONG- TERM MORTALITY IN HIGH- AND LOW-RISK PATIENTS WITH STEMI Unadjusted mortality in high-risk and low-risk STEMI stratified by door-to-balloon times Int J Cardiol Dec 1;224: doi: /j.ijcard Epub 2016 Sep 5.
32 IMPROVED SURVIVAL OF PATIENTS WITH STEMI 3 6 HOURS AFTER SYMPTOM ONSET IS ASSOCIATED WITH INTER- HOSPITAL TRANSFER FOR PPCI AT A LARGE REGIONAL STEMI PROGRAM VS. IN-HOSPITAL THROMBOLYSIS IN A COMMUNITY HOSPITAL Mortality level in the IHT group and inter-hospital transfer group with PPCI at 30 days and 1 year Thirty-day survival curves in the IHT group and inter- hospital transfer group with treated with PPCI Med Sci Monit Feb 27;23: DOI: /MSM e-issn
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