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1 ﻣ Research & Scientific Journal of Ardabil University of Medical Sciences & Health Services Vol 2, No 8, Jun-Sep 2003 ﺳﻜﺘﻪ ) ( ﺧﻄﺮ ﻣﺨﺘﻠﻒ ﺷﺎﻣﻞ ﻗﺮ ﻧﺴﺨﻪ SPSS ﻳﺎﻓﺘﻪ ﻫﺎ (OR=٥/٤ %٥ CI=/ -٥/) ﺣﺎﺻﻞ ﺷﺪ p=٠/٠٥ ( ﺑﺎ %٥ CI=٠/٥-٧/) /٧

2 ﻣﺠﻠﻪ ﻋﻠﻤﻲ ۴۶ ﻣﻘﺪﻣﻪ WHO ﻣﻄﺎﻟﻌﻪ [٥ ] () (Case Reports) ٠[ ] ٥٠ [٥ ٠] ٦٠ ٠٠ ﺗﺎ ٨٠ ٧٠ ٥٠ ٧٠ ٨ [ -٨] ﻧﺘﺎﻳﺞ ﻣﺘﻐﻴﺮ [٠ ] ٠٠ ﻫﻤﭽﻨﻴﻦ ﻣﻄﺎﻟﻌﻪ ﺳﻴﺮﻳﺘﻮ [] ﻧﺴﺨﻪ SPSS [٤ ] 1- Oral Contraceptives 2-Sirtho

3 ۴۷ (%٥/٤) ﻧﻔﺮ (%٤/) ﻧﻔﺮ ٦ ﻳﺎﻓﺘﻪ ﻫﺎ ﺷﺎﻫﺪ ٧ ﺷﺎﻫﺪ ﻫﺎ ٨/٧ ٤ ٧ ٤ ٦/ ٨ ﻣﺼﺮﻓﻲ ٦/٥ ٨ ٧/٥ / /٥ HD /٤ ٨ ٥ ٠ ٠ / ٧ ٦ (%٥) ﻧﺎ ﻣﺸﺨﺺ ﺳ ٦٠/٦ (%/٦) ٥٥ %/ () ﻫﻤﺎﻧﮕﻮﻧﻪ ﻛﻪ ﻣﺸﺨﺺ (OR=٨/٦ OR=) ٦ ﻫﻤﭽﻨﻴﻦ (%٨/٧) ﻧﻔﺮ ٤ ﺮ ﺳﻜﺘﻪ =/٤ ( (%) ﻧﻔـﺮ ﺣﺎﺻﻞ ﺷﺪ CI=/-٥/ ﺑﺎ OR ) ٧ ﻣﺼﺮﻓﻲ ﻲ ﺷﺎﻫﺪ ﻫﺎ %٦/ HD ٥/٤ ٦٦/٧ ٦ ٨٤/٦ / ٨ ٧/٧ ٥ ٦ / ٧٥ ٨ / ٧/٥ ٧٦/ ٠ ٦/٥ ٥ ﺣﺎﺻﻞ ﻧﻴﺎﻣﺪ ٥ ٧ /٥ (%٤٨/٦) ﻧﻔﺮ ٨ ﻣﻌ

4 ﻣﺠﻠﻪ ﻋﻠﻤﻲ ۴۸ /٨ /٤ [] OR= /٧ HD ﺷﺎﻣﻞ ﺣﺎﺻﻞ ﺷﺪ p=٠/٠٥ ( ﺑﺎ CI=٠/٥-٧/) ﺑﺤﺚ HD ٧٠ ٦٠ [-٨] [٦ ٠ ٤ ] WHO ٧٠ [٧ -] ٨٠-٠٠ ٧٠ ٦٠ ٥٠ ﺗﺎ WHO ﻣﻄﺎﻟﻌﻪ ﺣﺎﺿﺮ [٥ ] ٤/٥ (CI=/٥-٦/) OR= (CI=/٦ -/٨) ﻣﺼﺮﻓﻲ OR=٨/٦ ﺷﺎﻧﺲ /٤ OR=/٧ OR=/٦ (CI=/-٦/٤) /٨ ٤ ﻛﻨ [٤] ﺳﺎﻟﻪ ٤-٤٤ 1- Lidegaard p=٠/٠٥ 2- Petitti ٤٠٨ ﭘﺘﻴﺘﻲ

5 ۴۹ 1-Jordan WM Pulmonary embolism Lancet 1961; Lorentz IT Parietal lesion and Enovid BMJ 1962; Inman WH, Vessey MP Investigation of deaths from pulmonary, coronary, and cerebral thrombosis and embolism in women of childbearing age Br Med J 1968 Apr; 2(599) Vessey MP, Doll RInvestigation of relation between use of oral contraceptives and thromboembolic disease Br Med J 1968 Apr; 2(599) Startwell PE, Masi AT, Arthes FG, Greene GR, Smith HE Thromboembolic and oral contraceptives an epidemiological case-ontrol study Am J Epidemiol 1969; 90(5) Oral contraceptive and venous thromboembolic disease, surgically confirmed gallbladder disease, and breast tumors report from the Boston Collaborative Drug Surveillance Program Lancet 1973; Sartwell PE Oral contraceptives and thromboembolism a further report Am J Epidemiol 1971 Sep; 94(3) Collaborative Group for the Study of Stroke in Young Women Oral contraception and increased risk of cerebral ischemia or thrombosis N Engl J Med 1973; Vessey MP, Lawless M, Yeates D Oral contraceptives and nonfatal stroke in healthy young women Annals of Internal Med 1989; (88) Hannaford PC, Croft PR, Kay CR Oral contraception and stroke Evidence from the Royal College of General Practitioners' Oral Contraception Study Stroke 1994 May; 25(5) Siritho S, Thrift AG, McNeil JJ, You RX, Davis SM, Donnan GA, et al Risk of ischemic stroke among users of the oral contraceptive pill The Melbourne Risk Factor Study Group Stroke 2003 Jul; 34(7) Petitti DB, Sidney S, Bernstein A, Wolf SH, Quesenberry C, Ziel HK Stroke in users [٠ ] ﮔﺬﺷﺘﻪ ﻣﻨﻘﻄﻊ [٤ ] ٥ ٧/٥ (p < ٠/٠٥) [٨ ٧ ٥] ﻫﺮ ﭼﻨﺪ ﻧﺘﺎﻳﺞ ﻣﻨﺎﺑﻊ

6 ﻣﺠﻠﻪ ﻋﻠﻤﻲ ۵۰ of low-dose oral contraceptives N Engl J Med 1996 Jul; 335(1) WHO Collaborative Study of Cardiovascular Diseases and Steroidal Hormone Contraception Ischemic stroke and combined oral contraceptives vests of an International Multicenter case-control study Lancet 1996; Lidegaard O Oral contraception and risk of a cerebral thromboembolic attack results of a case-control study BMJ 1993 Apr; 306 (6883) Collaborative Group for the Study of stroke in young women Oral contraceptives and stroke in young women associated risk factors J Am Med Assoc 1975 Feb; 231(7) Inman WH, Vessey MP, Westerholm B, Engelund A Thromboembolic disease and the steroidal content of oral contraceptives A report to the Committee on Safety of Drugs Br Med J 1970 Apr; 2(703) Mann JI, Vessey MP, Thorogood M, Doll SR Myocardial infarction in young women with special reference to oral contraceptive practice Br Med J 1975 May; 2(5965) Mann JI, Inman WH Oral contraceptives and death from myocardial infarctionbr Med J 1975 May; 2(5965) Ory HW Association between oral contraceptives and myocardial infarction a review J Am Med Assoc 1977 June; 237(24)

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