Medical Marijuana in Canada, 2014: Panacea or Blowing Smoke. Dr. Paul Daeninck Mr. Brent Zettl
|
|
- Florence Lester
- 5 years ago
- Views:
Transcription
1 Medical Marijuana in Canada, 2014: Panacea or Blowing Smoke Dr. Paul Daeninck Mr. Brent Zettl
2 Presenter Disclosure Presenter: Brent Zettl Relationships with commercial interests: President and CEO of Prairie Plant Systems Inc. and CanniMed Ltd.
3 Mitigating Potential Bias Mr. Zettl has 14 years of experience in the Canadian Medical Marijuana industry. Prairie Plant Systems Inc. has been working with and providing medical marijuana to Health Canada since The parent company has provided product for clinical trials and has on-going clinical trials. Generic names will be used and will speak to the regulations, science and production as a whole.
4 Botany of Cannabis Cannabis sativa Cannabaceae family Close relative of Humulus (hop plant used in beer) Origin in Central Asia Annual herb Dioecious (separate female and male plants) Page, 2014
5 Female Cannabis Flowers Page, 2014
6 Page, 2014
7 The discovery of THC: 50 th anniversary in April 2014! THC was first discovered by Raphael Mechoulam and Yehiel Gaoni (Weizmann Institute, Israel) Their landmark paper Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish was published April 20, 1964 in The Journal of the American Chemical Society Page, 2014
8 The (phyto)cannabinoids THC is just one of a large group of plant metabolites called the cannabinoids; found only in cannabis There are more than 110 known cannabinoids The major cannabinoids are: ElSohly & Slade, 2005
9 9 -Tetrahydrocannabinol (THC) THC produces many of the psychoactive effects of cannabis Also the main therapeutic compound present: Analgesic* Antiemetic* Appetite stimulant* Antispastic activity* *Reported in literature Gaoni and Mechoulam, 1964; Joy et al, 1999
10 Cannabidiol (CBD) Non-psychoactive cannabinoid in cannabis Second most important cannabinoid after THC Cannabidiolic acid (CBDA) is the precursor Present in hemp and some medicinal strains Anti-inflammatory, neuroprotective, anxiolytic, antiepileptic, antipsychotic* May attenuate memory-impairment effects of THC Role in treating pediatric epilepsy (Dravet syndrome) *Reported in literature Hampson et al, 1998; Leweke et al, 2012; Mechoulam et al, 2007; Pertwee, 2008
11 Cannabinoid receptors: CB 1 and CB 2 THC is an agonist at both cannabinoid receptor-1 (CB 1 ) and cannabinoid receptor-2 (CB 2 ) CB 1 and CB 2 are G-protein coupled receptors (GPCRs) CB 1 is presynaptic CB 1 is the most abundant receptor in the human brain! Pertwee, 2001; Mackie, 2008
12 The patient then sends in the original medical document and an application form to the Licensed Producer of their choice. Medical Marijuana Current MMPR Process (Effective June 30, 2013) Compassionate end-of-life care or specified medical conditions Patient Symptoms where conventional treatments have failed The Licensed Producer then validates the client s medical document and application form and adds them as a client. Once the client orders product, it is then shipped via secured courier to their door. A physician completes a medical document on behalf of patient for access to medicinal marihuana
13 Medical Marijuana How is it different than street marijuana? A System of Accountability: Grown under strict Good Production Practices (GPP) guidelines enforced by Health Canada Tested for the presence of microbials, mycotoxins, & metals Pesticide use? Delivered to the patient in a safe manner (i.e. secure courier or XPressPost with proof of signature) Concentrations of cannabinoids require to be captured on the label (usually THC and CBD) Recall ability given lot designation
14 Cannabis Strains Thousands of cannabis strains exist 13 licensed producers listed 118 strains (May 1 st, 2014) Most strains were developed for recreational use and still use common names high THC (15-20%) very low CBD (<1%) Varying amounts of minor cannabinoids (CBC, THCV, etc.) Patients report that cannabis strains differ in their effects Patients and cannabis growers generalize into two types: Indica sedative Relates to ratio of THC and CBD Sativa stimulating The difference between Sativa and Indica may relate to species or subspecies of Cannabis, but this is not clear Page, 2014
15 What to look for in a Licensed Producer Safety (testing for microbials and mycotoxins should be able to present lot back-up information if required) Consistency (every product will be the same from one order to the next) Reliability (production/product inventory availability) Knowledgeable (regulatory compliance, documentation and registration) Adverse Event Record Keeping (Every LP must have a system to capture adverse events)
16 Metals Quality Control Testing Natural Health Products (NHP) Division of Health Canada regulates the allowable amounts of Heavy Metals contaminant in the MM product Contaminants Tolerance (µg/kg/bw/day) Arsenic < 0.14 Cadmium < 0.09 Lead < 0.29 Mercury < 0.29
17 Microbial Quality Control Results Microbiological Analysis Pre- Irradiation Post- Irradiation Specification Total Coliforms < 1.8 MPN/g < 1.8 MPN/g < 3 MPN/g Total Aerobic/ Anaerobic Bacteria 200 CFU/g 0 CFU/g < 100 CFU/g Escherichia coli Absent Absent Absent Salmonella Absent Absent Absent Staphylococcus aureus Absent Absent < 100 CFU/g Yeasts and Molds 22,000 CFU/g < 33 CFU/g < 100 CFU/g Toxic Molds Aspergillus 2333 CFU/g Absent Penicillium 4000 CFU/g Absent Acremonium 1667 CFU/g Absent Chaetomium 7667 CFU/g Absent MPN: most probable number; CFU: colony forming units ID and Report
18
19 Potency Quality Control The profile of the MS-17/338 cultivar includes mainly THC and THCA, with minimal CBD (specification < 0.5% CBD)
20 Navigating the Health Canada Website 13 Licensed Producers to date (650 applicants as of May 1, 2014) Patient confusion over who to choose o What distinguishes one LP to another? o Does every LP grow under the same conditions? o Is the product safe? o What does Jack the Ripper and Green Kush mean? o Supply availability?
21 How to Apply The Patient s Process 1. Patient visits their Physician to discuss treatments for their indication. 2. Patient and Physician decide on medical marijuana as treatment. 3. Physician fills out a generic medical document (or a specific LP s medical document). 4. The Patient then submits their medical document along with their application form directly to an LP. 5. Once the LP registers the Patient, the Patient goes online to purchase their medicine.
22 Medical Document The Medical Document must include: 1. Patient s name and DOB 2. Daily quantity of dried marijuana to be used by the Patient and period of use 3. Health Care Practitioner s name, profession, business address, phone number, province authorized to practice in and license number 4. Attestation that the information contained is correct and complete 5. Physician signature (original only)
23 Address Health Care Practitioner Information Patient Information Physician Attestation and Signature Product choice Written Order
24 The LP s Patient Registration Process 1. Patient s original application form and medical document are received. 2. LP ensures that all documentation has been submitted and contacts the Physician s office to confirm details (prescription amount, authorization, etc.) 3. Once documentation is confirmed, LP registers the Patient in their computer system. 4. LP notifies the Patient that they are registered and they may now purchase their medicine.
25 Questions? References Elsohly, M.A. and Slade, D. (2005). Chemical constituents of marijuana: The complex mixture of natural cannabinoids. Life Sciences, 78, Gaoni, Y. and Mechoulam, R. (1964). Isolation, structure, and partial synthesis of an active constituent of hashish. Journal of the American Chemical Society 86, Hampson, A.J., Grimaldi, M., Axelrod, J. and Wink, D. (1998). Cannabidiol and (-) 9-tetrahydrocannabinol are neuroprotective antioxidants. Proceedings of the National Academy of Sciences 95, Joy, J.E., Watson, S.J., and Benson, J.A. (Eds.). (1999). Marijuana and Medicine: Assessing the Science Base. National Academies Press. Leweke, F.M., Piomelli, D., Pahlisch, F., Muhl, D., Gerth, C.W., Hoyer, C., Klosterkotter, J., Hellmich, M. and Koethe, D. (2012). Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. Translational Psychiatry 2, e94. Mackie, K. (2008). Cannabinoid Receptors: Where they are and what they do. Journal of Neuroendocrinology 20 (Suppl.1), Mechoulam, R., Peters, M., Murillo-Rodriguez, E. and Hanus, L.O. (2007). Cannabidiol recent advances. Chemistry and Biodiversity 4, Page, J. (2014). Introduction to cannabis, cannabinoids and the endocannabinoid system. CCIC Conference. Pertwee, R.G. (2001). Cannabinoid receptor ligands. Tocris Reviews 16, 1-8. Pertwee, R.G. (2008). The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin. British Journal of Pharmacology 153,
James Donaldson CEO and Executive Director
Welcome! James Donaldson CEO and Executive Director Dr. Natasha Ryz Chief Science Officer, Zenabis Cannabis 101 Introduction to Cannabis Plant Cannabis is a genus of flowering plants within the family
More informationCannabis. Member of the Cannabaceae family of flowering plants (along with hops) Cannabis sativa (v. sativa, indica, afghanica, ruderalis)
Member of the Cannabaceae family of flowering plants (along with hops) sativa (v. sativa, indica, afghanica, ruderalis) Only females flowers contain high concentrations of psychoactive oils (cannabinoids)
More informationResearch on Cannabis and PD: Is there any evidence?
Research on Cannabis and PD: Is there any evidence? Benzi M. Kluger, MD, MS Associate Professor of Neurology and Psychiatry Director Movement Disorders Center University of Colorado Denver DISCLOSURES
More information(B) A testing laboratory shall analyze a sample of at least one half of one percent of the
ACTION: Final DATE: 08/14/2017 9:26 AM 3796:4-2-04 Testing laboratory analysis requirements. (A) A testing laboratory shall analyze a sample of at least one half of one percent of the net weight of the
More informationResearch: Medical Cannabis
Research: Medical Cannabis Background The hemp plant Cannabis sativa (cannabis) is commonly known as marijuana and can be used as a therapy to alleviate symptoms such as pain and fatigue caused by chronic
More informationRecent trends in medical cannabis use in Canada
Recent trends in medical cannabis use in Canada Paul Grootendorst Faculty of Pharmacy, University of Toronto Department of Economics, McMaster University Cannabis therapeutic effects Cannabis has been
More informationMedical Marijuana. 1. is a plant species, variety known as hemp. 3. Tetrahydrocannabinol is an aromatic with low water solubility.
Medical Marijuana Questions from Part 1: 1. is a plant species, variety known as hemp. a. Cannabis sativa Linnaeus b. Cannabis sativa c. Cannabis indica d. Cannabis Lemark 2. The major psychoactive compound
More informationSUPER SNOUTS CBD150 & CBD300 OIL FOR DOGS & CATS
SUPER SNOUTS CBD150 & CBD300 OIL FOR DOGS & CATS Why choose Super Snouts CBD Oils? Super Snouts has an outstanding reputation for creating well researched, effective and affordable health supplements for
More informationPHYTOCANNABINOIDS AND THEIR MEDICINAL APPLICATIONS
Toll Free: 1.800.516.1504 info@vitaliset.com vitaliset.com Find us on Instagram! vitalisextractiontech PHYTOCANNABINOIDS AND THEIR MEDICINAL APPLICATIONS A recent history of prejudice against the cannabis
More informationCannabidiol as a potential treatment for anxiety disorders. Esther Blessing, MD PhD
Cannabidiol as a potential treatment for anxiety disorders Esther Blessing, MD PhD Overview History and of cannabidiol (CBD) and cannabis Safety and tolerability of CBD CBD pharmacology Clinical need for
More informationAgracan - LP. Palmerston Industrial Park Cannabis Cultivation Facility
Agracan - LP Palmerston Industrial Park Cannabis Cultivation Facility Legislative Background Legal access to dried marijuana for medical purposes was first provided in 1999. In 2000 individuals with a
More informationLearning Objectives 1/8/2019. Therapeutic Potential of the Marijuana-Derived Cannabinoids THC and CBD. Disclosures. Outline. Take home messages
Therapeutic Potential of the Marijuana-Derived Cannabinoids THC and CBD CECILIA HILLARD, PHD DEPARTMENT OF PHARMACOLOGY NEUROSCIENCE RESEARCH CENTER Disclosures Member of the Scientific Advisory Board
More informationCannabis Potency, Dosing & Safety by MCR Labs
Cannabis Potency, Dosing & Safety by MCR Labs Consumable Cannabis Products. Flower Concentrate Edible Consumed by Inhalation Inhalation Ingestion Onset Within 1 Minute Within 1 Minute 30-120 Minutes Duration
More information420 ADVISORY MANAGEMENT
THE CANNABIS ACT: WHAT DOES IT MEAN FOR CANADIANS? 420 CLINIC, LTD. OBJECTIVES At the end of the session, you will be able to: 1) Understand the ramifications of recreational cannabis legalization 2) Understand
More informationModel. Medical Access to Marihuana first established on a case by case basis using exemptions
Table 1: Legal Framework for Cannabis in Canada Legal Framework Section 56 Exemptions under Controlled Drugs and Substances Act (1999) Marihauna Medical Access Regulations (MMAR) 2001 Marihuana for Medical
More informationMedical Marihuana for Patients in the Lymphoma Setting. Speakers: Ruth Turner, RN, Con Rob Laister, PhD
Medical Marihuana for Patients in the Lymphoma Setting Speakers: Ruth Turner, RN, Con Rob Laister, PhD Medical Marihuana for Patients in the Lymhoma Setting Disclosure: No endorsement or promotion of marihuana
More informationTHE COMPLETE CBD GUIDE
THE COMPLETE CBD GUIDE WHAT IS CBD (CANNABIDIOL)? 2 WHERE DOES CBD COME FROM? 3 HOW DOES CBD WORK IN THE BODY? 4 HOW MUCH CBD DO I TAKE? 5-6 CBD OIL VS. HEMP OIL 7 CBD NOT THC 8 THE BENEFITS OF CBD 9 PETS
More informationCANNABIS FOR THE RHEUMATOLOGIST
CANNABIS FOR THE RHEUMATOLOGIST Dr Jagtar Singh Nijjar NIHR Clinical Lecturer in Rheumatology Disclosures None 1 Overview The history of cannabis use Anecdotal use of cannabis in chronic pain The biology
More informationMedicinal Marihuana Science, Redefined
Medicinal Marihuana Science, Redefined From Concept to Commercialization.... www.avantirx.com WELL BEYOND COMPLIANCE Medicinal Marihuana Science, Redefined... ARA Avanti Rx Analytics Inc. is a Health Canada
More informationHEALTH WELLNESS COMMUNITY
HEALTH WELLNESS COMMUNITY As with all modern medicines, our understanding of cannabis and its benefits has deepened over time thanks to groundbreaking advancements in research and technology. At Trilogy
More information9/13/2017. Marijuana and the Brain Matthew Wong, MD Assistant Professor, Department of Neurology, Epilepsy Section. Disclosures.
Marijuana and the Brain Matthew Wong, MD Assistant Professor, Department of Neurology, Epilepsy Section Disclosures Site principal investigator of studies of cannabidiol(epidiolex) in the treatment of
More informationResponsibility through testing THE HANDBOOK. Understanding Your Laboratory
Responsibility through testing THE HANDBOOK Understanding Your Laboratory Table of Contents Page3...Welcome Page 4...Submitting Samples Page 5...Setting the Standard Page 6...Top 10 Questions Page 7...Cannabinoid
More informationCANADIAN CANNABIS CRAZE (AND CONUNDRUM) Dr. Melissa Snider-Adler Chief Medical Review Officer DriverCheck Inc. Addiction Medicine Physician
CANADIAN CANNABIS CRAZE (AND CONUNDRUM) Dr. Melissa Snider-Adler Chief Medical Review Officer DriverCheck Inc. Addiction Medicine Physician AGENDA THC IMPAIRMENT A deep dive into THC vs. CBD Signs and
More informationUnderstanding the New Access to Cannabis for Medical Purposes Regulations
Understanding the New Access to Cannabis for Medical Purposes Regulations Health Canada August 2016 Table of Contents 1. Introduction 2. Health Canada's role 3. What it means for health care practitioners
More informationNew Discovery! 8/24/2015. The Endogenous Cannabinoid System THE ENDOCANNABINOID SYSTEM AND YOUR PATIENTS AND YOUR PATIENTS
THE ENDOCANNABINOID SYSTEM AND YOUR PATIENTS Mary Lynn Mathre, RN, MSN, CARN President and Co-founder, Patients Out of Time President and Founding member, American Cannabis Nurses Associates Judy R. Frates,
More informationSpecification Sheet : Hemp CBD Isolate
Specification Sheet : Hemp CBD Isolate Description Hemp CBD Isolate is a raw ingredient sold retail as is. It consists of extracted CBD isolate from Colorado. Application and Use Composition Organic Certification
More informationMEDICAL MARIJUANA: WHAT S THE EVIDENCE?
MEDICAL MARIJUANA: WHAT S THE EVIDENCE? L A U R A A. M A R K L E Y, M D B O A R D - C E R T I F I E D I N P E D I A T R I C S / G E N E R A L P S Y C H I A T R Y / C H I L D & A D O L E S C E N T P S Y
More informationMedical Cannabis use in the Older Patient
Medical Cannabis use in the Older Patient Dr. Amanjot Sidhu Division of Geriatric Medicine McMaster University Audience Poll What is the fastest-growing demographic of cannabis users? a) Ages 14-23 b)
More informationMEDICAL CANNABIS IN MINNESOTA
MEDICAL CANNABIS IN MINNESOTA MINNESOTA ACADEMY OF PHYSICIAN ASSISTANTS MARCH 18, 2016 TOM ARNESON, MD, MPH MDH OFFICE OF MEDICAL CANNABIS 2014: Minnesota becomes 22 nd state with a medical cannabis program
More informationMODIFICATION OF APPLICATION TO BECOME A LICENSED PRODUCER UNDER THE ACCESS TO CANNABIS FOR MEDICAL PURPOSES REGULATIONS
MODIFICATION OF APPLICATION TO BECOME A LICENSED PRODUCER UNDER THE ACCESS TO CANNABIS FOR MEDICAL PURPOSES REGULATIONS (ACMPR) (Disponible en français) This form should be used if you already submitted
More informationFaculty/Presenter Disclosure
Faculty/Presenter Disclosure Faculty: Philippe Lucas Relationships with commercial interests: Philippe Lucas is a Research Affilliate with the Centre for Addictions Research of BC, as well as VP, Patient
More informationThe Company. Beyond Pioneering
The Company Beyond Pioneering Standardisation Bedrocan is the world s most experienced producer of legal medicinal cannabis. We are currently the only company producing medicinal cannabis flos to good
More informationADVANCED CLINICAL CANNABINOID PROVIDER EXAM ACCP
ADVANCED CLINICAL CANNABINOID PROVIDER EXAM ACCP Page 1 1. In what year did the possession and transfer of cannabis for recreational use become illegal in the United States? A. 1937 B. 1941 C. 1933 2.
More informationCBD Oil: Anxiety Aid & Much More
CBD Oil: Anxiety Aid & Much More This often misunderstood hemp extract may be a health miracle for many. LISA TURNER NOV 1, 2017 betternutrition.com You ve probably heard of and wondered about CBD (cannabidiol),
More informationHistory Of Medical Cannabis
History Of Medical Cannabis Historical and archaeological evidence of widespread use in ancient times as medicine, food, textiles & for sacraments, rituals Possibly first domesticated crop Introduction
More informationCBD OIL BUYER S GUIDE
CBD OIL BUYER S GUIDE CBD OIL CBD (cannabidiol) oil has become incredibly popular for pets and with good reason. Dog owners are finding it helps their dogs with a number of different health issues. It
More information(THC) Delta9-tetrahydrocannabinol:
(THC) Delta9-tetrahydrocannabinol: Most prominent compound found in the cannabis plant found in the 1960 s. THC binds to the CB1 and CB2 receptors causing a change in the function of the cell it is binding.
More informationINFUSED II LABORATORY REPORT
1 of 1 879 Federal Blvd Denver, CO 80204 (303) 427-2379 License Number: 405-00008 405R-00011 INFUSED II LABORATORY REPORT Customer Name: Customer License: Batch Number: METRC Tag: Instrument Name: Triple
More informationCannabis: Therapeutic properties of the plant
Cannabis: Therapeutic properties of the plant Medicinal cannabis is still illegal to be used in South Africa. In a victory for marijuana users across South Africa, ConCourt has officially legalised cannabis
More informationObjectives. 1. Review controversy 2. Pathophysiology 3. Indications for Use 4. Adverse Effects 5. How Patients Access
Medical Marijuana Deb Evans, RN, MScN, CON(C), CHPCN(C) Clinical Nurse Specialist Pain and Symptom Management Team Juravinski Cancer Centre May 29, 2014 Objectives 1. Review controversy 2. Pathophysiology
More informationCannabis and the Endocannabinoid System
Cannabis and the Endocannabinoid System September 7, 2018 Bangkok, Thailand David Bearman, MD Goleta, California Executive VP, American Academy of Cannabinoid Medicine AACMSITE.org Shen Nung Ping
More informationMEDICAL CANNABIS IN MINNESOTA
MEDICAL CANNABIS IN MINNESOTA EPILEPSY & SEIZURES WELLNESS EXPO APRIL 16, 2016 MICHELLE LARSON, MPA MDH OFFICE OF MEDICAL CANNABIS 2014: Minnesota becomes 22 nd state with a medical cannabis program State
More informationCertificate of Analysis: Hemp Oil Liquid Emulsion-CE Product Name Hemp Oil Liquid Emulsion-CE Product Code BATCH LE17167 Date of Manufacture 28 July 2017 Botanical Source Industrial Hemp, grown and processed
More informationCannabis derived terpenes for sale
Cannabis derived terpenes for sale Buy real weed online! Your premium edibles. Cannabis Oil. Canabidol CBD cannabis oil (CBD Oli) is derived from EU approved, UK & US legal, industrial hemp (Cannabis Sativa
More informationMarijuana and Adolescents: Truth and Consequences. Disclosure Statement OBJECTIVES. Secondary Objectives. State of Marijuana in US
Marijuana and Adolescents: Truth and Consequences Clinical Advances in Pediatrics Symposium Children s Mercy Park September 28, 2017 Disclosure Statement I have no actual or potential conflict of interest
More informationThe Scientific Side of Medical Marijuana
The Scientific Side of Medical Marijuana Ken Mackie, MD Indiana University Bloomington, IN December 3, 2009 kmackie@indiana.edu Financial disclosures NIH (NIDA) - research grants Alzheimer s Association
More informationMedicinal cannabis. What is medicinal cannabis? What are cannabinoids? The endocannabinoid system
Medicinal cannabis What is medicinal cannabis? Broadly speaking, medicinal cannabis is cannabis prescribed to relieve the symptoms of a medical condition, such as epilepsy. It is important to make the
More informationInvestigational Pharmacy Cannabidiol treatment in Epilepsy
Jon Beck BS Pharm D Coordinator Investigational Pharmacy Disclosure I have no relevant financial relationships with a Commercial Provider Nebraska Medicine Omaha, NE Investigational Pharmacy Cannabidiol
More informationSusan Allen-Evenson Hosts: Laura Lagano, MS, RDN, CDN Prepare for the Next Level: Incorporating Holistic Cannabis in the Nutrition Practice
Susan Allen-Evenson Hosts: Laura Lagano, MS, RDN, CDN Prepare for the Next Level: Incorporating Holistic Cannabis in the Nutrition Practice Integrative Clinical Nutritionist, Laura Lagano MS, RDN, CDN
More informationMedicinal Marijuana: Closing the gap between anecdotal benefits and evidence-based research. Jonathan Kiesman, Pharmacist CanniMed Ltd.
Medicinal Marijuana: Closing the gap between anecdotal benefits and evidence-based research Jonathan Kiesman, Pharmacist CanniMed Ltd. Presenter Disclosure Presenter: Jonathan Kiesman Relationship with
More informationMedical Cannabis Program. Dr. Maureen Small Co Medical Director Andrea Sundberg Program Coordinator
Medical Cannabis Program Dr. Maureen Small Co Medical Director Andrea Sundberg Program Coordinator Disclaimer The following information is based upon research of current studies. The Department of Health
More informationMOTION FOR A RESOLUTION
European Parliament 2014-2019 Committee on the Environment, Public Health and Food Safety 2.10.2018 2018/2775(RSP) MOTION FOR A RESOLUTION further to Question for Oral Answer B8-0000/2018 pursuant to Rule
More informationCannabis and Cannabinoids Pharmacology, Toxicology, and Therapeutic Potential
Cannabis and Cannabinoids Pharmacology, Toxicology, and Therapeutic Potential Ethan Russo Editors The Haworth Integrative Healing Press An Imprint of The Haworth Press, Inc. New York London Oxford _ CONTENTS
More informationPage 1 of 5. Kriss Worthington. Honorable Mayor and Members of the City Council Councilmembers Kriss Worthington, Cheryl Davila, and Kate Harrison
Page 1 of 5 Kriss Worthington Councilmember, City of Berkeley, District 7 2180 Milvia Street, 5 th Floor, Berkeley, CA 94704 PHONE 510-981-7170, FAX 510-981-7177, EMAIL kworthington@cityofberkeley.info
More informationCannabis & Hemp therapeutic solutions
Cannabis & Hemp therapeutic solutions with Our Cannabis & Hemp quality standards Thanks to their rich characterization and proprietary extraction method, our therapeutic solutions are a reference point
More informationCannabidiol, or CBD, Benefits for Pain, Mental Illness & Anxiety
Cannabidiol, or CBD, Benefits for Pain, Mental Illness & Anxiety The use of medical marijuana continues to be an emotionally and politically charged issue. Although cannabis oil preparations have been
More informationProduct Data Sheet Hemp Oil 3% CBD. 1. General information. Best before: 06 / Product information: Appearance Ingredients CBD oil
1. General information 1.1 Product information: Appearance Ingredients CBD oil : CBD Oil in Glass bottle 10ml with dropper : Hemp extract and organic olive oil 1.2 Ingredients CBD Oil : Hemp extract :
More informationMedical Cannabis MATT WEBSTER DO, MS
Medical Cannabis MATT WEBSTER DO, MS Cannabis Sativa One of the oldest used drugs and medicinal remedies Most commonly abused illicit drug in the US There has been increasing access for medicinal MJ use
More informationSUPPLEMENTAL AGENDA MATERIAL for Supplemental Packet 2
Page 1 of 6 Sophie Hahn Councilmember District 5 SUPPLEMENTAL AGENDA MATERIAL for Supplemental Packet 2 Meeting Date: July 10, 2018 Item Number: 19 Item Description: Ordinance Allowing Currently Permitted
More informationSusan Audino, PhD S.A. Audino & Associates, LLC
Cachexia, Cancer, Chronic Pain, Epilepsy, Glaucoma, HIV, AIDS, Multiple Sclerosis, Nausea, ALS, Crohn s, Hepatitis C, Anorexia, Arthritis, Migraine, Parkinson s, Damage to the Nervous Tissue of the Spinal
More informationMedical Cannabis. Danial Schecter, MD, CCFP. Vocational Rehabilitation Association November 7th, Executive Director Cannabinoid Medical Clinic
Medical Cannabis Danial Schecter, MD, CCFP Executive Director Cannabinoid Medical Clinic Vocational Rehabilitation Association November 7th, 2014 Conflict of Interest This program has not received financial
More informationThe Shifting Federal Regulation of Cannabis Products
The Durham Bar 2019 CLE Program The Shifting Federal Regulation of Cannabis Products Erica M. Jackson, FDA Partner K&L Gates February 6, 2019 Copyright 2018 by K&L Gates LLP. All rights reserved. OVERVIEW
More informationLegalizing Industrial Hemp in the States. NCSL Agricultural Task Force Meeting December 9, 2014 Presented by: Eric Steenstra President, Vote Hemp
Legalizing Industrial Hemp in the States NCSL Agricultural Task Force Meeting December 9, 2014 Presented by: Eric Steenstra President, Vote Hemp What is Industrial Hemp? Industrial hemp is the non-psychoactive,
More informationCANNABIS LEGALIZATION: SUPPORT MATERIAL FOR MANITOBA PHYSICIANS
CANNABIS LEGALIZATION: SUPPORT MATERIAL FOR MANITOBA PHYSICIANS 1. GENERAL INFORMATION Cannabis 101 What is cannabis? Cannabis is a product derived from the Cannabis sativa plant. Cannabis contains hundreds
More informationCBD HOPE AND/OR HYPE?
CBD HOPE AND/OR HYPE? Gregor Zorn STCM 3.0 Confernce 19.1.2019 Bern, CH Cannabidiol (CBD) Isolated 1940 (Adams, 1940), Structure identified in 1963 (Mechoulam and Shvo, 1963) Major cannabinoid in hemp
More informationTrends in medical cannabis use in Canada,
Trends in medical cannabis use in Canada, 2001-2016 Paul Grootendorst PhD* Igor Korolija PharmD Minsup Shim PhD Leslie Dan Faculty of Pharmacy, University of Toronto *Corresponding author: paul.grootendorst@gmail.com
More informationMedical vs Recreational Use of Cannabis. 11 th December 2017
1 Medical vs Recreational Use of Cannabis 11 th December 2017 2 Defining Cannabis and Chemical Constituents Cannabis is a plant species. Two main Cannabis sub-species are Cannabis Sativa and Cannabis Indica.
More informationCannabis 101 Safe, Versatile & Effective Medicine
Cannabis 101 Safe, Versatile & Effective Medicine Cannabis is a treasure trove of healing. Dr. Raphael Mechoulam, the father of cannabis science is an organic chemist and professor of Medical Chemistry,
More informationDEMYSTIFYING CANNABIS Renee Davis MA Traditional Roots Conference Friday May 15, pm
DEMYSTIFYING CANNABIS Renee Davis MA Traditional Roots Conference Friday May 15, 2015 2-4pm BACKGROUND AND HISTORY Cannabis is one of humanity s oldest economic plants, in use for over 6000 years for food
More informationCannabis Testing Laboratory Solutions
Cannabis Testing Laboratory Solutions We are the cannabis testing instrument experts. When purchasing analytical equipment, it is important to know that you are not just buying an instrument but investing
More informationColin Fetter Partner, Edmonton Office Direct: Presented by:
Colin Fetter Partner, Edmonton Office cfetter@brownleelaw.com Direct: 780-497-4867 Presented by: Introduction Medical Marijuana / Cannabis Duty to accommodate Recent case law Practical considerations Upcoming
More informationMedical Cannabis use in the Older Patient. Amanjot Sidhu, MD, FRCPC Division of Geriatric Medicine McMaster University
Medical Cannabis use in the Older Patient Amanjot Sidhu, MD, FRCPC Division of Geriatric Medicine McMaster University Disclosure Relationships with commercial interests: Grants/Research Support: none Speakers
More informationCBD USER GUIDE CUREDNUTRITION.COM CBD INFUSED PRODUCTS MADE FROM COLORADO-GROWN ORGANIC HEMP
CBD USER GUIDE CUREDNUTRITION.COM CBD INFUSED PRODUCTS MADE FROM COLORADO-GROWN ORGANIC HEMP table of contents All about CBD What are Cannabinoids What is CBD? How is CBD different from THC? The Endocannabinoid
More informationCannabis 101 Safe, Versatile & Effective
Cannabis 101 Safe, Versatile & Effective Cannabis is a treasure trove of healing. Dr. Raphael Mechoulam, He is the father of cannabis science is an organic chemist and professor of Medical Chemistry, at
More informationTHERAPEUTIC FOCUS. Direct Effects Cannabinoid Therapy: Medical Cannabis Without Psychoactive & Systemic Effects F I G U R E 1. By: Ronald Aung-Din, MD
THERAPEUTIC FOCUS Direct Effects Cannabinoid Therapy: Medical Cannabis Without Psychoactive & Systemic Effects By: Ronald Aung-Din, MD MEDICAL CANNABIS CONTROVERSY F I G U R E 1 There is no greater medical
More informationThe Sale of Cannabis in Pharmacies. Michael H. Ghobrial, PharmD, JD Associate Director, Health Policy American Pharmacists Association
The Sale of Cannabis in Pharmacies Michael H. Ghobrial, PharmD, JD Associate Director, Health Policy American Pharmacists Association Development This activity was developed by the American Pharmacists
More informationMedicinal Cannabis. Patient Log Book. Record your cannabis use and find the right dose
Medicinal Cannabis Patient Log Book Record your cannabis use and find the right dose 1 Introduction A federal system is in place for medicinal cannabis that is distinct from recreational sales. To get
More informationSECTION V: EMPLOYEES POLICY 5375 MEDICAL MARIJUANA, HEMP & CANNABIDIOL (CBD)
Regardless of a student, employee, parent or any individual s status as a medical marijuana license holder, marijuana is not allowed on the premises of the district or in any school vehicle or in any personal
More informationCDHA 2016 Fall Symposium. Speaker Handout Files. For registered attendees only
CDHA 2016 Fall Symposium Speaker Handout Files For registered attendees only Providing Care in a Marijuana Legal World Heather Rogers, BSDH heatherrdh@heatherrdh.com Objectives We will discuss some of
More informationMedical Cannabinoids for the Management of Chronic Noncancer Pain
Medical Cannabinoids for the Management of Chronic Noncancer Pain Dr Mark A. Ware MBBS MSc McGill University 12 June 2018 Disclosures Grants: CanniMed Consulting: CHI Inc Emmes 1 Canadian Consortium for
More informationMedicinal Marijuana: The Canadian Journey
Medicinal Marijuana: The Canadian Journey Nady el-guebaly MD Professor & Head, Addiction Division, UofC Research Director, Alberta Gambling Research Institute Chief Examiner, ISAM Certification Disclosures:
More informationand areas of cannabis research that require further study:
The CCIC Podcast March 25, 2015 This month: Prof. Raphael Mechoulam Interview by Dr. Mark A. Ware www.ccic.net/podcast Introduction Hello and welcome to the CCIC Podcast. The CCIC Podcast is a series of
More informationMARIJUANA & THE EFFECTS ON THE BRAIN
MARIJUANA & THE EFFECTS ON THE BRAIN Sheryl Ryan, MD Professor of Pediatrics Chief, Division of Adolescent Medicine, Penn State Health Hershey Medical Center DISCLOSURES I have no relevant financial relationships
More informationOutcome. Educating Ohio Providers On The Basics Related To Recommending Medical Marijuana. Connie J. Cerilli, APRN, FNP-C
Educating Ohio Providers On The Basics Related To Recommending Medical Marijuana Connie J. Cerilli, APRN, FNP-C Outcome Participants will be able to list 3 approved medical conditions Participants will
More informationEducating Ohio Providers On The Basics Related To Recommending Medical Marijuana. Connie J. Cerilli, APRN, FNP-C
Educating Ohio Providers On The Basics Related To Recommending Medical Marijuana Connie J. Cerilli, APRN, FNP-C Outcome Participants will be able to list 3 approved medical conditions Participants will
More informationADOPTED REGULATION OF THE DEPARTMENT OF TAXATION. LCB File No. R092-17
ADOPTED REGULATION OF THE DEPARTMENT OF TAXATION LCB File No. R092-17 EXPLANATION Matter in italics is new; matter in brackets [omitted material] is material to be omitted. AUTHORITY: 1-21, NRS 453A.370,
More informationUse of Cannabinoids in Medical Practice
Use of Cannabinoids in Medical Practice Annual Scientific Assembly Family Medicine Review 2016 Murray Opdahl BSPE, MD, CCFP Objectives Briefly present: An overview of available cannabinoids Concerns voiced
More informationMedical Cannabis Then and Now. Jeffrey Skell, PhD
Medical Cannabis Then and Now Jeffrey Skell, PhD 2016 Agenda A Brief History of Cannabis Drug Properties Is Cannabis Developable? The Source of All That Trouble Traditional Medicine in the Far East and
More informationCannabis Botany: Naturally Medicinal By Sir Ross Cannabis READ ONLINE
Cannabis Botany: Naturally Medicinal By Sir Ross Cannabis READ ONLINE If you are searching for a book by Sir Ross Cannabis Cannabis Botany: Naturally Medicinal in pdf format, then you have come on to faithful
More informationCannabis in the Workplace: Lessons Learned. Sponsored by:
Cannabis in the Workplace: Lessons Learned Sponsored by: Andrew Freedman Dr. Melissa Snider-Adler Neil Tidsbury Holly Hale Session Overview: 20-Minute address 30-Minute Q&A Andrew Freedman Co-Founder &
More informationThe Determination of CBD and General Cannabinoid Content in Hemp Oils Using HPLC with UV Detection
High Performance Liquid Chromatography No. HPLC-018 The Determination of CBD and General Cannabinoid Content in Hemp Oils Using HPLC with UV Detection Introduction Medical marijuana generally possesses
More informationUltimate Guide: Everything You Need To Know Before Buying CBD Hemp Oil
Ultimate Guide: Everything You Need To Know Before Buying CBD Hemp Oil Cannabidiol (CBD) is taking the health and wellness community by storm. Between news coverage and personal testimonies, it is a highly
More informationLecture: Medical Marijuana Long term effects and interac ons with common medicines Neuropharamacology of the brain with cannabis
Lecture: Medical Marijuana Long term effects and interac ons with common medicines Neuropharamacology of the brain with cannabis William Morrone, DO Robert Piccinini, DO Endocannabinoids in Disease and
More informationSteven G. Kinsey, PhD Associate Professor, Department of Psychology West Virginia University
Steven G. Kinsey, PhD Associate Professor, Department of Psychology West Virginia University sgkinsey@mail.wvu.edu Any opinions expressed are my own and do not reflect any official position of WVU beanpot.co
More informationMedical Marijuana A Primer for Pharmacists
Medical Marijuana A Primer for Pharmacists Emory S. Martin, PharmD FASHP Texas Society of Health System Pharmacists Learning Objectives Recognize key components of the endocannabinoid system Identify possible
More informationGeorgia Cannabidiol Study Frequently Asked Questions
Georgia Cannabidiol Study Frequently Asked Questions 1. Why was the Georgia Cannabidiol Study initiated? In January 2014, Representative Allen Peake visited with Haleigh Cox, a 4-year-old girl with severe
More informationCustomer Sample Type Method Technique
Sample ID 18A23000003 Cannabis Potency HPLC-UV Chemistry Cannabidivarin (CBD-V) 1.29 mg/dose Cannabidiol (CBD) 646.50 mg/dose Cannabigerol (CBG) Tetrahydrocannabivarin (THC-V) 24.7 mg/dose
More informationINTRODUCTION BACKGROUND INFORMATION
CONTENTS INTRODUCTION... 3 BACKGROUND INFORMATION... 3 Recent International Decisions in Relation to Cannabis... 3 United States of America... 3 Australia and New Zealand... 4 1. What was the process that
More informationCannabis in the treatment of Autism:
Cannabis in the treatment of Autism: Are we ready? Deb Karhson, PhD and Lawrence Fung, MD, PhD Cannabis Anecdotal Data: Comparing Epilepsy and Autism+ Science of Cannabinoids: Endocannabinoid System Receptor
More information