IVHEM MEETING PROSPECTUS IVHEM INTERNATIONAL VIRAL HEPATITIS ELIMINATION MEETING.

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1 INTERNATIONAL VIRAL HEPATITIS ELIMINATION MEETING Amsterdam, the Netherlands November 2018 (t.b.c.) Translating diagnostic and therapy advances into broad applications for the elimination of viral hepatitis MEETING PROSPECTUS

2 ADVANCING HEALTH GLOBALLY THROUGH INNOVATIVE PROGRAMS DESIGNED FOR THE HEALTHCARE PROFESSIONAL

3 TABLE OF CONTENTS Welcome 4 Meeting description 5 Needs assessment 5 Target audience 5 Program description 5 Meeting objectives 5 Accreditation 5 Learning outcomes & impact 6 Assessment method 6 Conference participation grants 7 Enduring materials 7 Committees 8 Infographics 2016 edition 10 Acknowledgements 11 #18 International Viral Hepatitis Elimination Meeting () Meeting Prospectus 3

WELCOME Jordan Feld, MD, MPH Meeting Chair Margaret Hellard, MBBS, FRACP, FAFPHM, PhD Meeting Chair Hepatitis B and C affect more than 320 million people globally and can lead to liver disease and

8% of the world s population) are chronically infected with HBV, and over 700,000 deaths are attributable to it annually. An estimated 80 million people (globally, 1.

Key issues to be addressed are how to translate research outcomes into public health policy and practice to meet the 2030 elimination targets.

4 WELCOME Jordan Feld, MD, MPH Meeting Chair Margaret Hellard, MBBS, FRACP, FAFPHM, PhD Meeting Chair Hepatitis B and C affect more than 320 million people globally and can lead to liver disease and mortality from liver failure and hepatocellular carcinoma. More than 248 million people (3.8% of the world s population) are chronically infected with HBV, and over 700,000 deaths are attributable to it annually. An estimated 80 million people (globally, 1.1%) are chronically infected with the hepatitis C virus (HCV), resulting in nearly 500,000 deaths annually. Key issues to be addressed are how to translate research outcomes into public health policy and practice to meet the 2030 elimination targets. During this two day meeting experts in viral hepatitis from around the globe will examine current evidence on how to implement programs that improve the prevention of viral hepatitis, and increase the number of people accessing testing and treatment. Involving community organizations, researchers, public health practitioners and clinicians, the program includes practical examples of innovative intervention studies, country elimination programs and novel funding mechanisms testing and treatment, all focusing on meeting the 2030 targets. We invite you to contribute to elimination of viral hepatitis and look forward to welcoming you to this unique meeting in Amsterdam Jordan Feld & Margaret Hellard #18 4 International Viral Hepatitis Elimination Meeting () Meeting Prospectus

MEETING DESCRIPTION NEEDS STATEMENT The field of viral hepatitis treatment is undergoing major changes and is on the verge of a paradigm shift.

5 MEETING DESCRIPTION NEEDS STATEMENT The field of viral hepatitis treatment is undergoing major changes and is on the verge of a paradigm shift. There are great hopes for the elimination of viral hepatitis. Many new treatment options are becoming available through the introduction of Direct Acting Antivirals (DAAs) and are providing great hopes for decreasing the burden of disease and simplifying the treatment of viral hepatitis. The International Viral Hepatitis Elimination Meeting () is a global forum for the exchange of practical experiences in the translation of diagnostic and therapy advances into broad applications that accelerate progress toward elimination of viral hepatitis as a public health threat. The program features outstanding international experts that address strategies regarding testing & screening, care & cure, prevention, and innovative models to finance elimination strategies. TARGET AUDIENCE PROGRAM DESCRIPTION This 2-day meeting consists of invited lectures, roundtable discussions and abstracts. In order to ensure an interactive workshop setting, much time is allocated to discussion. MEETING OBJECTIVES To provide a forum for knowledge exchange and discussion of practical experiences of advances in diagnostics and clinical management of viral hepatitis. To provide a toolbox for practical application of research & development, for evidence based policy making To facilitate cross-disciplinary discussion on barriers and challenges to come to the elimination of viral hepatitis ACCREDITATION This workshop will not be a CME accredited activity. Healthcare professionals, including but not limited to clinicians, researchers, policy makers, virologists, pharmacologists, industry representatives, and those looking beyond the individual patient and who would like to be involved in the elimination of viral hepatitis. International Viral Hepatitis Elimination Meeting () Meeting Prospectus 5

6 MEETING DESCRIPTION LEARNING OUTCOMES & IMPACT After attending this program participants will be able: To identify the roadblocks and the challenges in implementing viral hepatitis elimination strategies To recognize the needs from a public health perspective and respond to these needs by reshaping their policy making approaches To further develop new or already existing foundations for political commitment, national planning and program improements. To translate the latest research and technologies into clinical policy and practice for delivering adequate continuum of hepatitis services. ASSESSMENT METHOD To assess the meeting, Virology Education provides each delegate with a detailed feedback form where they can assess the speakers, whether or not the meeting objectives were met, their intent to change, the rationale behind their motivation to attend, the general logistics of the meeting, and much more. All the questions are then fully analyzed and a comprehensive report is created and shared with the committee members. These reports help us better understand our delegates and how to make the next meeting better. For a maximum response rate, we invite the chairs of each session to encourage the participants to take a few minutes and complete the feedback forms. We are also introducing a web-based application to allow participants access to the feedback forms electronically 6 International Viral Hepatitis Elimination Meeting () Meeting Prospectus

7 CONFERENCE PARTICIPATION GRANTS The conference participation grants provide healthcare professionals with the opportunity to attend a conference they would otherwise be unable to attend due to financial restrictions. All applications include a CV, a motivation letter, and potentially an abstract (requirements vary depending on the workshop). These are submitted via an independent CPG portal and are evaluated against the assessment criteria using robust, impartial and independent peer review processes by the Grant Review Committee. This process will ensure that only the highest quality, most relevant and most competitive research is accepted but that it is. The grants are supported by the financial contributions allocated by the sponsor, who, has no control, influence, or involvement in the selection process of the attendees whatsoever. Priority is given to applicants who have actively participated in original research or scientific work that is being presented at the meeting and/or those who will profit most from participating in order to improve their daily clinical management. These grants help defray costs for registration, travel and accommodation for delegates and foster their ability to form valuable professional networks and develop vital collaborations. Conference participation grant applications will be solicited, selected and awarded by an expert Grant Review Committee. ENDURING MATERIALS INFECTIOUS DISEASES ONLINE Enduring information presented at the conference will be freely retrievable and widely disseminated to reach thousands of virtual participants beyond the walls of the conference center. Infectious Diseases Online is a premier online platform offering scientific materials in special topical areas and proceedings of conferences. By accessing the website, visitors have full access to: Abstract Books Meeting Reports Workshop Presentations Webcasts All the data on Infectious Diseases Online is organized by workshop and date, making the materials highly organized and easy to find. The meeting proceedings will also be published on the meeting website. International Viral Hepatitis Elimination Meeting () Meeting Prospectus 7

Rotterdam, the Netherlands Jordan Feld MD,

MD, PhD Athens University Medical School,

Institute, Melbourne, Australia University

8 COMMITTEES ORGANIZING COMMITTEE Charles Boucher MD, PhD Erasmus Medical Center, Rotterdam, the Netherlands Jordan Feld MD, Toronto Centre for Liver Disease, Toronto, Canada Manal El-Sayed MD, PhD Ain Shams University, Cairo, Egypt Angelos Hatzakis MD, PhD Athens University Medical School, Athens, Greece Margeret Hellard MBBS, FRACP, FAFPHM, 'Funmi Lesi FWACP, FMCP Michael Ninburg Hepatitis John Ward MD PhD Burnet Institute, Melbourne, Australia University of Lagos, Lagos, Nigeria Education Project, USA U.S. Centers of Disease Control and Prevention, USA 8 International Workshop on NASH Biomarkers Meeting Prospectus

9 SCIENTIFIC COMMITTEE Isabelle Andrieux-Meyer - HIV/HCV Team Lead, Drugs for Neglected Diseases Initiative, Geneva, Switzerland Evaldo Stanislau Affonso Araújo - Assistant- Doctor, University of São Paulo Hospital das Clínicas Infectious Diseases Division, São Paulo, Brazil Maia Butsashvili - Director, Health Research Union, Tblisi, Georgia Jude Byrne - Senior Project Officer, Australian Injecting & Illicit Drug Users League (AIVL), Canberra, Australia Graham Cooke - Clinician scientist, Imperial College London, London, UK Andrea Cox - Professor of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA Emalie Huriaux - Director of Federal & State Affairs, US National Viral Hepatitis Roundtable, Project Inform, San Francisco, CA, USA Kenneth Kabagambe - Executive Director and Founder, The National Organization for People Living with Hepatitis B (NOPLHB), Makere, Uganda Achim Kautz - CEO, Leberhilfe Projekt gug, Cologne, Germany Shiv Kumr Sarin - Senior Professor and Head, Hepatology, & Director, Institute of Liver and Biliary Sciences, Delhi, India Khin Pyone Kyi - President of Board of Directors, Myanmar Liver Foundation, Rangoon, Myanmar Jeffrey Lazarus - Affiliated Professor, CHIP, Copenhagen, Denmark Ying-Ru Lo - Coordinator HIV, Hepatitis and Sexually Transmitted Infections Unit, WHO Western Pacific Regional Office, Manilla, Philippines Liudmyla Maistat - Policy and Advocacy Manager, Medicines Patent Pool, Geneva, Switzerland Shruti Mehta - Deputy Chair, Department of Epidemiology, Johns Hopkins School of Medicine, Baltimore, MD, USA Rosmawati Mohamed - University of Malaya, Kuala Lumpur, Malaysia Ponsiano Ocama - Associate Professor and Chair, Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda Jean-Michel Pawlotsky - Professor of Medicine, Hôpital Henri Mondor, Paris, France Huma Qureshi - Pakistan Medical Research Council, Islamabad, Pakistan Homie Razavi - Managing Director, Center for Disease Analysis (CDA), Louisville, CO, USA Tatjana Reic - President, European Liver Patients Association, Brussels, Belgium Anya Sarang - President, Andrey Rylkov Foundation for Health and Social Justice, Moscow, Russia Marcelo Silva - Head of Hepatology and Liver Transplant Unit, Austral University Hospital, Buenos Aires, Argentina Wendy Spearman - Head of Division of Hepatology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa Lara Strick - Infectious Disease Physician & Clinical Assistant Professor, Washington Department of Corrections & University of Washington, Tumwater & Seattle, WA, USA Mark Thursz - Professor of Hepatology, Imperial College London, London, UK Imam Waked - Professor of Medicine, National Liver Institute, Shebeen El-Kom, Egypt Stefan Zeuzem - Professor of Medicine, J.W. Goethe University Hospital, Frankfurt, Germany Francesco Marinucci - Head HIV/HCV Unit, FIND, Geneva, Switzerland International Viral Hepatitis Elimination Meeting () Meeting Prospectus 9

10 INFOGRAPHICS 2016 EDITION OCCUPATION COUNTRIES The majority of the 111 delegates that attended the previous worked as medical doctor (53%), or researcher (22%). Medical doctor (MD) Researcher Nurse NGO / Other activist 53% 22% 6% 6% 13% 111 delegates from 24 different countries participated in Most delegates were from Europe (68%), but also US (12%), Africa (10%), and Asia (10% were represented. WORKPLACE TYPE The majority of the 111 delegates attending worked for a (university) hospital. Others were employed by an NGO, university, pharmaceutical company, government agency, or other. Other 8% Pharmaceutical Company 14% University 16% Government 10% RETURNING PARTICIPANTS 11% of participants (n=12) attended more than one. (University) Hospital 36% NGO 16% MEETING OBJECTIVES Below is indicated to what extent participants indicated that the meeting objectives were met. 1 Identify the roadblocks and the challenges to come to an International approach to eliminate viral hepatitis 2 Identify the needs from the public health perspective 97% 97% 3 Facilitate cross-disciplinary discussion 72% 4 Create a platform for collaboration and national action plans 58% 10 International Viral Hepatitis Elimination Meeting () Meeting Prospectus

11 ACKNOWLEDGEMENTS SPONSORS TITANIUM LEVEL SUPPORTER CONTRIBUTOR International Viral Hepatitis Elimination Meeting () Meeting Prospectus 11

12 ACKNOWLEDGEMENTS ENDORSERS MEETING PARTNERS AFEW International Интeрнeшн LOCAL MEETING PARTNERS HEPATITIS INFO ACADEMIC PARTNERS 12 International Viral Hepatitis Elimination Meeting () Meeting Prospectus

13 FOR MORE INFORMATION, PLEASE CONTACT US AT: VIROLOGY EDUCATION Biltstraat BJ Utrecht the Netherlands International Viral Hepatitis Elimination Meeting () Meeting Prospectus 13

IVHEM 2019 REQUEST FOR SUPPORT INTERNATIONAL VIRAL HEPATITIS ELIMINATION MEETING.

IVHEM 2019 REQUEST FOR SUPPORT INTERNATIONAL VIRAL HEPATITIS ELIMINATION MEETING. INTERNATIONAL VIRAL HEPATITIS ELIMINATION MEETING 2019 AMSTERDAM, THE NETHERLANDS 22-23 NOVEMBER 2019 REQUEST FOR SUPPORT OVERVIEW INTRODUCTION TO The 5th edition of was organized on 6-7 December 2018