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6 t ( m m : s s. d MEDICA URODYNAMIC REPORTS FD vlpp ND SD vlpp MCC VLMa p1 ves ml cmh2o p2 abd cmh2o p4 det cmh2o..... Q :.1 1: : : :4.58 6:2.7 ml/s The Medica-Menfis automatic report generation facility is a very useful and attractive feature. Reports can be customised to suit individual requirements. Samples of reports already designed are included in the binder. All reports are provided with the Pico Smart. More than one report can be generated for any study for example, data automatically included in a narrative report, and other reports showing traces, nomograms etc can also be generated. can be Any one of the standard reports may be selected for the Pico Bright.

7 Q (ml / s) Q (ml / s) Any logo and contact details can be inserted Patient: Rose Petal ID: 911RP Birth date: 9/7/2 2 Physician Mr Waterfall : Procedure date: 23/9/213 Gender: Referring Physician: F Dr Martin Uroflowmetry: Waiting Time - Maximum Flow 19.ml/s Time to Maximum 7.7s Average Flow 1.ml/s Flow Time 5% -95% Vol. 2.4s Residual Volume 23ml Flow Time 31.8s Voided Vol. at 95.7ml Max. Flow Voiding Time 33.3s Voided Volume 319.ml 7 Liverpool Nomogram (Q max) 4 Liverpool Nomogram (Q ave) Volume(ml) Printed on: 1/1/ Volume(ml) Sample, Joe

8 Any logo and contact details can be inserted PATIENT NAME: Vera Lynne DATE OF BIRTH: 28/1/1965 HOSPITAL ID No: VL1789 PHYSICIAN: Yvonne Mason Vera Lynne is a 48 year old female who complains of urinary leakage with excercise. CYSTOMETRY SUMMARY: The patients bladder was filled at a rate of 5ml/min in a sitting position with first sensation occuring at an infused volume of 47 mls, normal desire occuring at an infused volume of 266 mls and strong desire occuring at an infused volume of 3 mls. Cystometric capacity is 37mls. OBSERVATIONS: Urodynamic Stress Incontinence was demonstrated The cough LPP was 133.8cmH2O Detrusor Overactivity was absent PRESSURE FLOW SUMMARY: The patient voided 275mls at an average flowrate of 8.1ml/s and a maximum flowrate of 18.1ml/s. The detrusor pressure at maximum flow was 21.8cmH2O cm H2O and the average detrusor pressure was 6.5cmH2O cm H2O. The post-void residual volume was 32mls OBSERVATIONS: The flow was continuous and the patient stated that this was a normal void. This void was normal COMMENTS: This patient has failed conservative treatment for her stress incontinence and a tape procedure may be considered Procedure date: 22/1/213 Printed on: 1/1/214 Demo 2

9 t ( m m : s s. d Any logo and contact details can be inserted Patient: Sample, Joe ID: Birth date: 7/9/1946 Gender: M Operator: Mr Smith Referrer: Dr Brown Complaint: Intravesical obstruction; Diagnosis: Notes: Date: 11/6/213 Cystometry FD vlpp ND SD vlpp MCC VLMa p1 ves ml cmh2o p2 abd cmh2o p4 det :.1 1: : : :4.58 6:2.7 cmh2o..... Q ml/s Pump Rate 5ml/min Infused Volume 219ml Pves (cmh2o) Pabd (cmh2o) Pdet (cmh2o) Vol (ml) Compl. (ml/cmh2o) 1st Desire (FS) Normal Desire (ND) Strong Desire (SD) Maximum Cys. Capacity (MCC) MEDICA S.p.A.

10 t ( m The patient was filled at 5ml/min with first desire occurring at an infused volume of 88 ml/min, normal desire occurring at an infused volume of 99 ml/min and strong desire occurring at an infused volume of 12 ml/min. The maximum cystometric capacity was 219 mls with a detrusor pressure of 8.9 cmh2o Pressure Flow Study (Voiding Phase) $ VLMa ml p1 ves cm H2O p2 abd 13 cm H2O p4 det cm H2O 2. Q m l/ s 6 : : : : : : Waiting Time 56.3s Opening detrusor pressure 155.9cmH2O Opening Time 53.9s Detrusor pressure at Maximum flow 139.9cmH2O Flow Time 82.3s Average detrusor pressure 15.3cmH2O Voiding Time 99.9s Maximum detrusor pressure 174.cmH2O Maximum Flow 7.1ml/s Closure pressure Average Flow 3.4ml/s Voided Volume 277ml Residual Volume 25ml The patient voided 277ml with a maximum flow rate of 7.1ml/s at a detrusor pressure of 139.9cmH2O and an average flow rate of 3.4ml/s. The average detrusor pressure was 15.3cmH2O Leak Point Pressure The patient leaked at a Vesical LPP of / and/or a Valsalva LPP of 15.5cmH2O. MEDICA S.p.A. Urodynamics report Genesis Medical LTD

11 PATIENT DETAILS: Name: Alan Test3 Hospital number: 123 DOB: 15/3/1951 Sex: F Any logo and contact details can be inserted Operator: Mr Smith Referring Physician: Dr Brown CLINICAL DETAILS: Freq Urgency Noct USI Hesitancy Pain Stream good poor FILLING PHASE: FD:135mls ND: 163mls SD: 294mls Maximun vol: 294ml Detrusor end-filling pressure:. cm H2O Rate of filling: 5ml/min Detrusor activity: Hyper Normal Compliance: Normal Reduced Cough test: DO +ve -ve BLADDER APPEARANCE: (supine) Reflux: No Yes left right both Outline: Normal Trabec Divetic Bladder neck: At rest: Open Closed Descent Cough: Open Closed Descent Printed on: 1/1/214 Test3, Alan

12 Any logo and contact details can be inserted VOIDING PHASE: Volume voided: 38ml Flowrate (Qmax): 12.3ml/s Detrusor pressure at Q. Max: 27.4cmH2O Able to interrupt micturition: BLADDER APPEARANCE: (erect) Reflux: No Yes left right both Outline: Normal Trabec Divetic yes no not tested PVR: ml Sitting Standing INTERPRETATION: Bladder neck: At rest: Open Closed Cough: Open Closed Leak Bladder neck: Normal Descent Descent Tight Signed: Date: Printed on: 1/1/214 Test3, Alan

13 Any logo and contact details can be inserted Patient: Sample, Joe ID: Birth date: 7/9/1946 Gender: M Physician: Mr Smith Referring Physician: Dr Brown Cystometry: (Filling Phase) Leaked Volume 25ml Infusion Speed 5ml/min Infused Volume 219ml Pves (cmh2o) Pabd (cmh2o) Pdet (cmh2o) Vol (ml) Compl. (ml/cmh2o) 1st Desire (FS) Normal Desire (ND) Strong Desire (SD) Maximum Cys. Capacity (MCC) Pressure Flow Study: (Voiding Phase) Time at Maximum Flow 7.5s Opening Pressure 155.9cmH2O Flow Time 82.3s Pressure at Maximum Flow 15.3cmH2O Voiding Time 99.9s Average Pressure 15.3cmH2O Maximum Flow 7.1ml/s Maximum Pressure 174.cmH2O Average Flow 3.4ml/s Closure Pressure 174.cmH2O Voided Vol. at Max. Flow 176.ml Voided Volume 277ml Residual Volume 25ml Markers Details First Desire Valsalva Leak Point Normal Desire Strong Desire Valsalva Leak Point Maximum Cystometric Capacity Invitation to Micturate Time (hh:mm:ss) :2:5 :2:5 :3:2 :3:26 :5:1 :5:24 :6:2 Pves (cmh2o) Pabd (cmh2o) Pdet (cmh2o) Inf. Vol. (ml) Inf. Speed (ml/min) Printed on: 1/1/214 Sample, Joe

14 p det( c mh2o) I CS O b s t r u c t e d 6 4 Eq u iv o c a l 2 Un o b s t r u c t e d Leak Point Pressure: Q m a x = 7. 1 Pd e t a t Q m a x = Ab r a m s / G r if f it h s Nu m b e r ( Pd e t a t Q m a x - 2 * Q m a x ) = Re s u lt = O b s t r u c t e d Detrusor leak Point Pressure / Valsalva leak Point Pressure 15.5cmH2O Minimum Abdominal Pressure / Cough Leak Point Pressure / Q ( m l/ s ec ) Printed on: 1/1/214 Sample, Joe

15 Procedure Date: 11/6/213 Printed on: 1/1/214 Sample, Joe

16 June 214 PEBAX is a copolymer polyeter-amide, biocompatible material with high mechanical features that allow the manufacture of catheters with very thin walls. The smooth surface makes catheter introduction easy and painless Connector Colour Meaning Remark NEUTRAL Infusion way To be connected to the pump line BLUE Bladder way To be connected to Pves YELLOW Urethral way To be connected to Pura RED Rectal way To be connected to Pabd * Replacement product of Life-Tech consumables Dual Lumen Cystometry Catheters CAT No. Description Qty Price 2CYS-6LE PEBAX Dual Lumen Catheter, 6Fr with incorporated extension line 1 box of *2CYS-8PE PVC Dual Lumen Catheter, 8Fr 1 box of with incorporated extension line (DLC-7-PT) 2CYS-9E PEBAX Dual Lumen Catheter, 9Fr with incorporated extension line 1 box of *2CYS-6L PEBAX Dual Lumen Catheter, 6Fr 1 box of boxes boxes 67. (DLC-6D) 2CYS-8P PVC Dual Lumen Catheter, 8Fr 1 box of boxes 5+ boxes *2CYS-9 (DLC-9D) PEBAX Dual Lumen Catheter, 9Fr 1 box of boxes 5+ boxes

17 2TIE-8P PVC Dual Lumen Coude tip catheter, 8Fr 1 box of CYS-6 PIG PEBAX Dual Lumen Pigtail tip catheter, 1 box of Fr Rectal Pressure Catheters CAT No. Description Qty Price *1AR-5TI Rectal Pressure Catheter with introducer 1 box of 1 36., 5Fr, (RPC-PT) Closed PVC balloon 1AR-5TC (541 &5415) x25 Rectal Pressure Catheter, 5Fr, Slit PVC balloon 1 box of 1 1 box of *2AR-9T (RPC-9 / ERPC) PEBAX Dual Lumen Rectal Pressure Catheter, 9Fr 3mm Closed Polyisoprene balloon 1 box of boxes 5+ boxes Cystometry/UPP Catheters CAT No. Description Qty Price *3omni-8P PVC Triple Lumen CMG/UPP Catheter, 8Fr 1 box of (DLUPP) 2 4 boxes 8. 2omni-8P PVC Dual Lumen CMG/UPP Catheter, 8 Fr During UPP measure Urethral Pressure ONLY (not simultaneous Pura Pves) 5+ boxes box of 1 7.

18 Catheter Sets CAT No. Description Qty Price CPS-D-6MX Cystometry Pressure Set: Includes 1 box of PEBAX 2CYS-6LE 6Fr dual lumen bladder pressure catheter & 1AR-5TI rectal pressure catheter with introducer CPS-D-8MX Cystometry Pressure Set: Includes PEBAX 2CYS-8PE 8Fr dual lumen bladder pressure catheter & 1AR-5TI rectal pressure catheter with introducer 1 box of Single Lumen Catheters CAT No. Description Qty Price *1PF-5PE PVC single-lumen bladder pressure catheter, 1 box of Fr (BPC-S) 1PF-4L PIG PEBAX bladder pressure catheter, 4Fr, Pigtail tip 1 box of BF-8P bladder filling catheter 1 box of Extension Tubing & Accessories CAT No. Description Qty Price Extension Line, clear, 18cm 1 box of *EXT-18 (PTTA-C) Box of 5 = 72.5 *EXT-18B (PTTA-B) Box of 5 = 72.5 *EXT-18R (PTTA-R) Box of 5 = 72.5 *SC2 (2-SC) Box of 25 = 4. *SC3 (4-SCA) Box of 25 = *WTP-LT2 (IPTS-LT2) WTP-SET Extension Line, Blue, 18cm 1 box of Extension Line, Red, 18cm 1 box of Way stop cock 1 box of Way stop cock 1 box of Infusion Pump Tubing Sets for Menfis Pico Smart Urodynamic system Life-Tech Janus 311A (LT2) Pump Infusion Pump Tubing Set for Menfis Pico Bright Urodynamic system 188 Pressure Transducer box of box of M Nova Transducer dome 1 box of MX848x2Sc Nova Transducer dome with 2 x stopcocks (discounted to 1 per box if using all Genesis urodynamic catheters) 1 box of MX96XY Logical Transducer dome 1 box of MX96x2Sc Logical Transducer dome with 2 x stopcocks 1 box of 5 27.

19 Pico Bright and Pico Smart System Support Service visits: one per annum recommended no parts 85 + VAT may be increased from time to time Maintenance Agreements Available from Genesis: Bronze Silver Gold Platinum One service visit per annum no parts 24 hour free replacement part service VAT if taken out and not allowed to lapse the price will never increase* One service visit per annum, all emergency calls out - no parts. 24 hour free replacement part service 16 + VAT if taken out and not allowed to lapse the price will never increase* One service visit per annum, all emergency calls out parts included up to 1-24 hour replacement part service 2 + VAT if taken out and not allowed to lapse the price will never increase* One service per annum, all emergency calls out - all parts included 24 hour replacement part service 24 + VAT if taken out and not allowed to lapse the price will never increase* * unless factors outside our control are involved. * if a contract is not taken out or lapses, the cost will be higher by 1% for each year that there has been no contract. Note: If there is a delay of more than 5 working days in approving a quotation for a repair, rental at 2 per week or part week will begin, until the part on loan is returned. Contact Genesis Medical Ltd on , Mon Fri Free telephone support is available to all users whether or not they are covered by a maintenance agreement.

CONTENTS PAGE UNIQUE FEATURES explained in full pg. 9 URODYNAMIC REPORTING overview pg. 11 Sample uroflowmetry report pg. 13 Sample consultation report pg. 14 Sample cystometry pressure-flow report (A)

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