Consultations and Assessment Fertility Specialist consultation 180 Ultrasound scan of uterus and ovaries 100 AMH measurement 80 Semen analysis 100

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1 We hope this price list will help you assess the cost of your consultations, investigations and treatment. It provides information about what is included in the cost and how we make a refund if your treatment does not take place for any reason. At any time, if you have any questions about the fees, payments or refunds, please contact us as soon as possible on to speak to a member of staff. Consultations and Assessment Fertility Specialist consultation 180 Ultrasound scan of uterus and ovaries 100 AMH measurement 80 Semen analysis 100 IVF and ICSI Treatment Package 4000 Includes all screening tests: Female: HIV, Hepatitis B core antibodies, Hepatitis B surface antigen, Hepatitis C blood test Male: HIV, Hepatitis B core antibodies, Hepatitis B surface antigen, Hepatitis C blood test Female: Rubella, Chlamydia, vaginal swab Male and Female Haemoglobinopathy screening Male: Karyotype, Y microdeletions and CF staus if low sperm count Includes all clinical interactions incorporating: All teatment planning visits, consents, scans, blood tests, egg collection under sedation, ultrasound guided embryo transfer, pregnancy scan, one follow up consultation and first counselling session. Includes advanced embryology incorporating: Closed culture embryo incubation Embryoscope with time lapse-monitoring of your embryos Blastocyst culture of embryos to day 5 / 6 Vitrification of surplus embryos First year of storage Annual storage fee for embryos 250 Annual storage fee applies after first year of storage Frozen embryo transfer 1000 Includes all blood tests if natural cycle or monitoring if constructed cycle, and pregnancy scan. Price List applicable from 16 March 2018 SM Nelson, BSc MRCOG PhD Muirhead Professor of Obstetrics and Gynaecology H Lyall, MD MRCOG Consultant and Honorary Senior Lecturer in Reproductive Endocrinology and Assisted Conception: Isabel Traynor BA Hons Lead Nurse Mrs Ruth Simpson, Co-ordinator Tel: Fax: Enquiries@glasgowroyalfertilityclinic.co.uk Level 2, New Lister Building, Royal Infirmary, Glasgow G31 2ER The University of Glasgow charity number SC004401

2 Treatment with Donor Eggs or Sperm Donor Egg Recipient Treatment Package known Donor 5500 Includes all screening tests of both recipent and donor: Includes IVF and ICSI cycle incorporating: All scans, blood tests, egg collection under sedation, ultrasound guided embryo transfer, vitrification of surplus embryos and first year of embryo storage, pregnancy scan, one follow up consultation and first counselling session for donor and recipient Includes all clinical interactions incorporating: Closed culture embryo incubation Embryoscope with time lapse-monitoring of your embryos Blastocyst culture of embryos to day 5 / 6 Vitrification of surplus embryos Frozen embryo transfer into recipient Annual embryo storage fee after first year 250 Oocyte donation with Institut Bernabeau 1000 Puchase of donor sperm from European Sperm Bank Cost per straw of ICI sperm 559 euros Cost per straw of IUI sperm 589 euros Required pregnancy slot of 1 of 10 families 500 euros Courier for ESB to GRFC 295 euros Administration 275 Intra-uterine insemination (IUI) with donor sperm 840 Ovulation induction and IUI with donor sperm 1240 Treatment with Surrogate 5900

3 Pre-implantation Genetic Screening (PGS) Consultations and Assessment Fertility Specialist consultation 180 Ultrasound scan of uterus and ovaries 100 AMH measurement 80 Semen analysis 100 ICSI Treatment Package for PGS 3800 Includes all screening tests: Female: HIV, Hepatitis B core antibodies, Hepatitis B surface antigen, Hepatitis C blood test Male: HIV, Hepatitis B core antibodies, Hepatitis B surface antigen, Hepatitis C blood test Female: Rubella, Chlamydia, vaginal swab Haemoglobinopathy screening Male: Karyotype, Y microdeletions and CF staus if low sperm count Includes all clinical interactions incorporating: All scans, blood tests, egg collection under sedation, ICSI, embryo culture and first year of embryo storage, one follow up consultation and first counselling session. Includes advanced embryology incorporating: Closed culture embryo incubation Embryoscope with time lapse-monitoring of your embryos Blastocyst culture of embryos to day 5 / 6 Trophocetoderm biopsy of embryo Vitrification of embryos PGS using Next-Generation Sequencing (NGS) Price per embryo PGS with NGS each sample (1 st 4 th ) 500 PGS with NGS each sample (5 th 8 th ) 200 Each sample thereafter 150 Includes embryo biopsy, and sample transportation costs PGS costs must be paid prior to shipping embryos to Genesis Genetics First frozen embryo transfer of PGS tested embryos 700 Includes all blood tests if natural cycle or monitoring if constructed cycle, and pregnancy scan. Frozen embryo transfer of subsequent PGS tested embryos 1000 Price List applicable from 16 March 2018 SM Nelson, BSc MRCOG PhD Muirhead Professor of Obstetrics and Gynaecology H Lyall, MD MRCOG Consultant and Honorary Senior Lecturer in Reproductive Endocrinology and Assisted Conception: Isabel Traynor BA Hons Lead Nurse Mrs Ruth Simpson, Co-ordinator Tel: Fax: Enquiries@glasgowroyalfertilityclinic.co.uk Level 2, New Lister Building, Royal Infirmary, Glasgow G31 2ER The University of Glasgow charity number SC004401

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5 Pre-implantation Genetic Diagnosis (PGD) with Karyomapping ICSI Treatment Package for PGD 3800 Includes all screening tests: Female: HIV, Hepatitis B core antibodies, Hepatitis B surface antigen, Hepatitis C blood test Male: HIV, Hepatitis B core antibodies, Hepatitis B surface antigen, Hepatitis C blood test Female: Rubella, Chlamydia, vaginal swab Male and Female Haemoglobinopathy screening Male: Karyotype, Y microdeletions and CF staus if low sperm count Includes all clinical interactions incorporating: All scans, blood tests, egg collection under sedation, ICSI, embryo culture and first year of embryo storage, follow up consultation and first counselling session Includes advanced embryology incorporating: Closed culture embryo incubation Embryoscope with time lapse-monitoring of your embryos Blastocyst culture of embryos to day 5 / 6 Trophocetoderm biopsy of embryo Vitrification of embryos if treatment already licensed for PGD by HFEA, licencing of new conditions will incur 600 charge. PGD for Single Gene Disorders 4500 Includes PGD Karyomapping for up to 9 embryos Additional charge for up to 19 embryos 1500 Includes compulsory genetic counselling, embryo biopsy, sample transportation costs, and testing even if man/woman have different mutations of same condition, collection of DNA from family members, confirmation of genetic mutation and and design of custom moleular probes for PGD PGD for Two Genetic Disorders 5000 Includes PGD Karyomapping for up to 9 embryos Additional charge for up to 19 embryos 1800 Includes compulsory genetic counselling, embryo biopsy, sample transportation costs, and testing even if man/woman have different mutations of same condition, collection of DNA from family members, confirmation of genetic mutation and and design of custom moleular probes for PGD PGD for Chromosomal Rearrangements using NGS 3000 Includes PGD for up to 6 embryos Additional charge per embryo in excess of Price List applicable from 16 March 2018 SM Nelson, BSc MRCOG PhD Muirhead Professor of Obstetrics and Gynaecology H Lyall, MD MRCOG Consultant and Honorary Senior Lecturer in Reproductive Endocrinology and Assisted Conception: Isabel Traynor BA Hons Lead Nurse Mrs Ruth Simpson, Co-ordinator Tel: Fax: Enquiries@glasgowroyalfertilityclinic.co.uk Level 2, New Lister Building, Royal Infirmary, Glasgow G31 2ER The University of Glasgow charity number SC004401

6 Includes compulsory genetic counselling, embryo biopsy, sample transportation costs, and testing even if man/woman have different mutations of same condition, collection of DNA from family members, confirmation of genetic mutation and and design of custom moleular probes for PGD First frozen embryo transfer of PGD tested embryos 700 Includes all blood tests if natural cycle or monitoring if constructed cycle, and pregnancy scan. Frozen embryo transfer of subsequent PGD tested embryos 1000

7 Fertility Preservation Consultations and Assessment Fertility Specialist consultation 180 Baseline ultrasound scan of uterus and ovaries 100 AMH measurement 80 Semen analysis 100 Egg Freezing Package 3200 Includes all screening tests: Female: HIV, Hepatitis B core antibodies, Hepatitis B surface antigen, Hepatitis C blood test Female: Rubella, Chlamydia, vaginal swab Haemoglobinopathy screening Egg freezing cycle including All scans, blood tests, egg collection under sedation, vitrification of oocytes and first year of oocyte storage, HFEA fee, one follow up consultation and first counselling session. Does not include medication Annual oocyte storage fee after first year 250 Embryo Freezing for Fertility Preservation Treatment Package IVF and ICSI cycle including All scans, blood tests, egg collection under sedation, vitrification of embryos and first year of embryo storage, follow up consultation and first counselling session. Does not include medication Advanced embryology including: Closed culture embryo incubation Embryoscope with time lapse-monitoring of your embryos Blastocyst culture of embryos to day 5 / Annual embryo storage fee after first year 250 Sperm Freezing Package 425 Sperm freezing per sample 175 Annual storage 250 Use of Frozen eggs 2000 All scans, blood tests, thawing, ICSI of vitrifed oocytes, embryo transfer, HFEA fee, follow up consultation and first counselling session. Does not include medication Price List applicable from 16 March 2018 SM Nelson, BSc MRCOG PhD Muirhead Professor of Obstetrics and Gynaecology H Lyall, MD MRCOG Consultant and Honorary Senior Lecturer in Reproductive Endocrinology and Assisted Conception: Isabel Traynor BA Hons Lead Nurse Mrs Ruth Simpson, Co-ordinator Tel: Fax: Enquiries@glasgowroyalfertilityclinic.co.uk Level 2, New Lister Building, Royal Infirmary, Glasgow G31 2ER The University of Glasgow charity number SC004401

8 Ovulation Induction Consultations and Assessment Fertility Specialist consultation 180 Baseline ultrasound scan of uterus and ovaries 100 AMH measurement 80 Semen analysis 100 Ovulation Induction and Intrauterine Insemination Package 1200 Ovulation induction including All scans, blood tests, intraruterine insemination, HFEA fee, follow up consultation and first counselling session. Does not include medication Ovulation Induction and Timed Intercourse 1000 Ovulation induction including All scans, blood tests, intraruterine insemination, HFEA fee, follow up consultation and first counselling session. Does not include medication Fertility Assessment Couples fertility assessment 460 Including: Baseline scan AMH measurement Female Chlamydia test Semen analysis Consultation Female fertility assessment 360 Including: Baseline scan AMH measurement Chlamydia test Consultation

9 IVF, ICSI, OI, PGS and PGDTreatment Drug Packages GnRH agonist / antagonist and 150IU FSH 725 GnRH agonist / antagonist and 225IU FSH 875 GnRH agonist / anatagonist and 300IU FSH 1025 GnRH agonist / antagonist and 375 IU FSH 1175 GnRH agonist / antagonist and 450IU FSH 1325 All IVF treatment packages include either hcg trigger or Buserelin trigger and luteal support. Once provided drugs cannot be reused and the full charge will apply Frozen Embryo Transfer (FET) Drug Packages FET with HRT constructed cycle 300 FET with HMG constructed cycle 700 Additional Clinical and Laboratory Services Administration costs for gamete/embryo transported within UK 250 Administration costs for gamete/embryo transported within UK including courier costs 350 Endometrial Scratch 225 Blood tests if not undertaking treatment package Cost per item: FSH 40, LH 40, Prolactin 40, Oestrogen 40, Progesterone 40, Chlamydia 65, Gonorrhoea 65, Rubella 40, Syphilis 40, HTLV I&II 50, Y-microdeletion 175, Karyotype (chromosomes) 280, Cystic Fibrosis 170, CMV 45, Miscarriage screen 720, Beta hcg 40, Haemoglobinopathy 60, Package of HIV, Hepatitis B core antibodies, Hepatitis B surface antigen, Hepatitis C blood tests 150 per patient. Price List applicable from 16 March 2018 SM Nelson, BSc MRCOG PhD Muirhead Professor of Obstetrics and Gynaecology H Lyall, MD MRCOG Consultant and Honorary Senior Lecturer in Reproductive Endocrinology and Assisted Conception: Isabel Traynor BA Hons Lead Nurse Mrs Ruth Simpson, Co-ordinator Tel: Fax: Enquiries@glasgowroyalfertilityclinic.co.uk Level 2, New Lister Building, Royal Infirmary, Glasgow G31 2ER The University of Glasgow charity number SC004401

10 Refund Policy Unfortunately, it is sometimes necessary to discontinue treatment for medical reasons. Depending on the stage of treatment at cancellation, a partial refund may be due. Full details of the cancellation fees for each of the treatment packages are in the table below Cancellation fees Cancelled cycle prior to egg retrieval 1000 Cancelled cycle due to no eggs retrieved 3000 Cancelled cycle due to failed fertilization of eggs / no transfer 3300 Cancelled IUI prior to insemination 350 Cancelled FET prior to embryo transfer 500 * Plus fees for ICSI, PGS/PGD or other procedures or other procedures already completed Non-refundable deposits This is relevant for any patient that wishes to cancel treatment before they have started stimulation injections or received monitoring (blood tests or scans) by the clinic. This non-refundable deposit is to cover costs incurred by GRFC prior to the patient electing to cancel. These costs include the consent appointment, co-ordination of treatment dates, prescriptions and all administrative processes. Blood tests will be charged separately as listed. 350 Terms and conditions The above fees may be subject to increases at any given time. Full payment must be received at least 14 days prior to commencement of payment. Payment methods Bank/Credit card or cheque/banker s draft made payable to the University of Glasgow and sent to: The GRFC Co-ordinator, Glasgow Royal Fertility Clinic, 2nd Floor, New Lister Building, Alexandra Parade, Glasgow Royal Infirmary, Glasgow G31 2ER. The treatment provided at Glasgow Royal Fertility Clinic is regulated by the Human Fertilisation and Embryology Authority and governed by the laws of Scotland.