NordicCell. Gynecology IVF/ART

Transcription

1 Gynecology IVF/ART

2 Company profile Our main business is to supply the Nordic gynecologists, fertility clinics and stem cell researchers with disposables and laboratory equipment. From our base in Copenhagen we provide our customers, clinicians and scientists with quick and kind service. We represent a large number of specialized brands within our field and we continuously update the range of products we offer. ApS Symbion Science Park Fruebjergvej 3 - Box 53 DK-2100 Copenhagen Denmark info@.com Phone: Fax: Vat Reg Nr: DK Trans-vaginal Fertiloscopy Uterus Fertiloscopy allows transvaginal laparoscopy, salpingoscopy, micro-salpingoscopy and hysteroscopy procedures to be carried out in a single 15 minute procedure. Uterine introducer The Fertiloscopy Kit consists of two disposable introducers: a 2,9 mm uterine introducer and a 4,0 mm transvaginal introducer. Transvaginal introducer Pouch of Douglas The uterine introducer is placed in the uterine cavity and used for injection of dye during the tubal patency test. Uterine introducer w/ obturator The transvaginal introducer is inserted in the Pouch of Douglas after first puncturing with a standard Veress needle, using saline as a distension medium. Uterine introducer - inflated Through the transvaginal introducer, a 2,9 mm hysteroscope with 4 mm irrigation sheath, 30 degree oblique lens and magnification should be inserted for carrying out Fertiloscopy. Transvaginal introducer w/ pointed obturator Fertiloscopy Kit 1/bag - 5/box Transvaginal introducer - inflated info@.com

3 Tubal patency check kit The ExEm Foam Kit gives a bright visualization of the fallopian tubes and enables easy recognition of tubal patency when performing Hysterosalpingo Foam Sonography (HyFoSy). The ExEm Foam Kit consists of 10 ml ExEm gel, 10 ml purified water, a 20 ml mixing syringe and a syringe connector. The ExEm gel creates an echogenic foam when mixed with purified water and air. During HyFoSy the fallopian tubes and the spill into the abdominal cavity will be reflected clearly on the ultrasound monitor for a short period of time. If not, the passage of one or both tubes is obstructed. Purified Water ExEm Gel The ExEm catheter is designed to prevent back-flow of the foam and to cause minimal discomfort for the patient, as no balloon is inflated. Two versions are available: with lamellae or beads. Syringe connector 20 ml Syringe ExEm Foam Kit + Multi P catheter 1/bag - 25/box ExEm Foam Kit + Nulli P catheter 1/bag - 25/box ExEm Foam Kit + Multi P catheter 1/bag - 10/box ExEm Foam Kit + Nulli P catheter 1/bag - 10/box ExEm Foam Kit (excl catheter) 1/bag - 25/box ExEm Foam Kit (excl catheter) 1/bag - 10/box ExEm catheter - Multi P 1/bag - 25/box ExEm catheter - Nulli P 1/bag - 25/box ExEm Catheter Nullipara catheter tip Multipara catheter tip Flexible Cervical Dilator The Flexible Dilator is ideal for dilating nulliparous or post-menopausal patients with cervical stenosis prior to endometrial, intrauterine and hysteroscopic procedures Disposable Flexible Dilator 1/bag - 25/box info@.com 3

4 HS Balloon catheters The HS Catheter is a soft latex-free balloon catheter designed to seal the uterus during infusion and provide a clear picture of the uterine cavity, with minimal obstruction of the internal os. Ideal for saline based examination of the uterine cavity and fallopian tube. The Shapeable HS Catheter has the same balloon as the HS catheter but the Shapeable HS Catheter can be shaped and curved to facilitate the introduction of the catheter HS Catheter 5 fr 1/bag - 10/box HS Catheter 7 fr 1/bag - 10/box Stylet for HS Catheter 1/bag - 10/box Shapeable HS Catheter 5 fr 1/bag - 10/box Shapeable HS Catheter 7 fr 1/bag - 10/box Shapeable HS Catheter The Miller Advanced Catheter is a new innovative balloon catheter. The tip is very soft and the guiding sheath is so thin that it can be placed into the cervical canal with no dilation required. Additionally the guiding sheath is made of a flexible memory material and can be shaped to fit the patient s anatomy Miller Advanced Catheter 25 cm 1/bag - 10/box ezinject ultra sonography catheter The ezinject catheter is a cost-effective pre-curved catheter for saline and foam based ultrasonography. There is no distal balloon to block your view of the uterus. The tip collar helps prevent leakage during infusion ezinject 1/bag - 10/box info@.com

5 Virtual diagnostic hysteroscopy Gel Instillation Sonohysterography (GIS ) allows for high quality ultrasound imaging of the uterine cavity. The GIS Kit consists of a syringe of ExEm gel and a specially designed catheter. By using ExEm gel and the catheter, backflow is eliminated and images are obtained in a stable manner without the need for an extra hand. The quality of the ultrasound examination is improved and results in a virtual hysteroscopy. GIS Catheter Nullipara N970 catheter tip Multipara M969 catheter tip GIS-Kit w/ N970 catheter 1/bag - 12/box GIS-kit w/ M969 catheter 1/bag - 12/box ExEm Gel Ultra sonography sampling catheters The IUI Memo is a thin catheter with a stiff shapeable tip facilitating the introduction of the catheter in stenotic patients. Very useful for foam and saline ultrasonography IUI Memo 4220 Memo 1/bag - 25/box The EchoSampler is a flexible two in one catheter used for both saline infusion sonohysterography and for ultrasound guided endometrial sampling EchoSampler /bag - 25/box The Probet is an endometrial suction curette with depth markings and a smooth rounded distal tip Probet /bag - 25/box info@.com 5

6 Vaginal specula - side opening The Weisman-Graves speculum is hinged on one side and open on the other side. This allows the speculum to be easily removed over a catheter or another device that has been inserted into the uterus. 90 speculum The speculum is made of durable quality stainless steel and the lower blade is longer than the upper blade, making the cervix more easily visible. Left opening Right opening Ref Product - 90 Speculum Speculum 7,5x2 cm - Left opening Speculum 10x4 cm - Left opening Speculum 12x4 cm - Left opening Speculum 7,5x2 cm - Right opening Speculum 10x4 cm - Right opening Speculum 12x4 cm - Right opening Ref Product - 45 Speculum Speculum 7,5x2 cm - Left opening Speculum 10x4 cm - Left opening Speculum 12x4 cm - Left opening Speculum 7,5x2 cm - Right opening Speculum 10x4 cm - Right opening Speculum 12x4 cm - Right opening 45 speculum 4-Bladed vaginal specula The 4-Bladed speculum eliminates the need to use both a speculum and a lateral retractor. The extra blades retain the vaginal side wall for optimal viewing and eliminates the need for an assistant to stabilize the vaginal opening. 4-Bladed speculum The speculum is autoclavable and made of durable quality stainless steel. Ref Product Bladed speculum 10x2 cm - M Bladed speculum 11,5x2 cm - L Bladed speculum 15x2,5 cm - XL info@.com

7 Disinfecting ultrasound transducers Oosafe Wipes are ready-to-use disinfection wipes. Effective against bacteria, funguses, and viruses (hepatitis, HIV, influenza and rota virus) Ref Product Oosafe disinfection wipes - 70 wipes/bucket Gynecological probe covers The Latex condom is a conventional powdered condom used for gynecological examinations Latex condoms for ultrasound probe 200 units Latex condom Copper wrapped intrauterine IUD The IUD soft-t 375 Luxe is an intrauterine contraceptive IUD with a vertical length of 36 mm and a width of 35 mm. The surface of the wrapped copper is 375 square mm. The position of the IUD can be checked by ultrasound as the body of the IUD is echogenic IUD soft-t 375 Luxe /bag - 15/box Hysterometer The Hysterometer has a smooth rounded tip and is used for measuring the depth of the uterine cavity. Three sizes: 10, 12, 14 with centimeter markings up to 15 cm. Hysterometer 10: 2,65-3,30 mm Hysterometer 10 1/bag - 25/box Hysterometer 12 1/bag - 25/box Hysterometer 14 1/bag - 25/box Hysterometer 12: 3,20-4,00 mm Hysterometer 14: 4,00-4,70 mm info@.com 7

8 Surgical gloves The Gentle Skin Premium OP glove is a new allergy friendly surgical latex glove. The glove is powder-free, polymer-coated, sterile and contains no thiuram or MBT, which are known to result in allergic reactions. The coating and surface refinement reduces the protein content drastically and creates an extra barrier between skin and latex. The Gentle Skin Isopretex OP glove is specially designed for latex-allergic persons. The Isopretex glove is a high-end glove made of polyisopretex that does not contain any latex proteins, no latex allergens and is free of vulcanization accelerators. Excellent extensibility and sensibility, with a textured surface that provides improved grip Gentle Skin Premium OP pairs/box Gentle Skin Premium OP - 6,5 50 pairs/box Gentle Skin Premium OP pairs/box Gentle Skin Premium OP - 7,5 50 pairs/box Gentle Skin Premium OP pairs/box Gentle Skin Premium OP - 8,5 50 pairs/box Gentle Skin Premium OP pairs/box Gentle Skin Isoprex OP - 6,5 50 pairs/box Gentle Skin Isoprex OP pairs/box Gentle Skin Isoprex OP - 7,5 50 pairs/box Gentle Skin Isoprex OP pairs/box Gentle Skin Isoprex OP - 8,5 50 pairs/box Hair, mouth and foot protection MopCap Mølnlycke - green 100/box Facemasks, Plenguard - tie 50/box Blue Shoe cover 100/box MobCap Facemask Shoe cover AlcoGel and hand cream DAX hand cream is an unscented moisturizing cream for hands and body. Easy to apply and leaves dry and chapped skin naturally soft without a sticky feeling. Contains sunflower oil (ph 5) Dax hand cream 250 ml 1 unit info@.com

9 IVF laboratory/examination gloves The Nitrilite Silky Ultra Clean gloves are very thin cleanroom nitrile gloves. The gloves are non powdered, non latex, MEA material tested and silk soft with a latex-like sensation. Double packed - 2 inner bags per master bag and 10 master bags per lined case Silky Ultra-Clean - S, 6-6½ 10 x 100 units Silky Ultra-Clean - M, 7-7½ 10 x 100 units Silky Ultra-Clean - L, 8-8½ 10 x 100 units Silky Ultra-Clean - XL, 9-9½ 10 x 100 units The Gentle Skin Grip glove is a new hypoallergenic polymer-coated, powder-free latex glove. Contains no thiuram or MBT and the coating and surface refinement reduces the protein content considerably which constitutes an additional barrier between skin and latex. The textured surface makes it easy to hold syringes, petri dishes, pipettes and other consumables Gentle Skin Grip S, 5-5,5 10 x 100 units Gentle Skin Grip S, 6-6,5 10 x 100 units Gentle Skin Grip M, 7-7,5 10 x 100 units Gentle Skin Grip L, 8-8,5 10 x 100 units Gentle Skin Grip XL, 9-9,5 10 x 100 units Heated incubator Cultura M is a reliable low cost heated incubator suitable for warming the sperm sample and catheter prior to the IUI procedure. Range: C ± 1 C Ref Product Cultura M incubator Laboratory detergent Detergent 7X is a neutral biodegradable low foaming laboratory detergent for use in tissue culture and molecular biology labs. It is made from anionic surfactants, special solvents and builders. Non-toxic for even the most sensitive organisms. Ref Product Detergent 7X - 1 liter Detergent 7X - 10 liters info@.com 9

10 Gynetics aspiration needles The Gynetics aspiration needles have a sharp V-shaped back-cut tip to ensure a smooth penetration of the follicle with a clean cut in the penetrated tissue. The visibility of the tip is excellent during ultrasound, due to the echogenic embossed marking on the tip. Aspiration sets with tubing for aspiration with a pump Ref Size Type OD/ID A B G Aspiration set, Rigid 33 cm 1,4/1, G Aspiration set, Rigid 33 cm 1,4/1, G Aspiration set, Rigid 33 cm 1,4/1, G Aspiration set, Rigid 33 cm 1,4/1, G Aspiration set, Rigid 35 cm 1,4/1, G Aspiration set, Rigid 35 cm 1,4/1, G Aspiration set, Rigid 35 cm 1,4/1, G Aspiration set, Rigid 35 cm 1,4/1, A B Single lumen aspiration needle Aspiration needles with luer lock connection for aspiration with a syringe Ref Size Type OD/ID A G Aspiration needle, Rigid 33 cm 1,4/1, G Aspiration needle, Rigid 35 cm 1,4/1, G Aspiration needle, Rigid with tubing 33 cm 1,4/1, G Aspiration needle, Rigid with tubing 33 cm 1,4/1, G Aspiration needle, Rigid with tubing 35 cm 1,4/1, G Aspiration needle, Rigid with tubing 35 cm 1,4/1,0 30 Luer needle with tubing Luer needle A Aspiration pumps The Rocket Suction Pump is a new digital aspiration pump that provides smooth, low volume vacuum at pre-determined negative pressures, allowing simple, low turbulence oocyte recovery. Immediate vacuum response and cut-off intuitive rotary control and blue LED vacuum display. The Craft Suction Pump provides smooth low volume vacuum at pre-determined negative pressures, resulting in low turbulence oocyte recovery. The duo-vac model includes a high vacuum function for clearing clogged aspiration needles. Ref Product Aspiration pump, Rocket Aspiration pump, Connection set Aspiration pump, CRAFT single Aspiration pump, CRAFT Duo-Vac info@.com

11 Aspiration probe cover The Microtek probe cover is telescopically folded and slides over the transducer in a simple place and pull move. The probe cover is made of EMA; a latex-free and non-powdered material. CE marked and MEA material tested Microtek probe cover 8x61 cm (2x50/box) 100 units Microtek probecover Snap cap tubes ml IVF snap cap tube - Nunc /500 box ml snap cap tube - Falcon MEA tested (*) 20/500 box ml snap cap tube - Falcon /500 box ml snap cap tube - Falcon /500 box Aspiration syringes ml BD Discardit II - MEA tested (*) 1/100 box ml BD Discardit II - MEA tested (*) 1/80 box ml BD Discardit II 1/100 box ml BD Discardit II 1/80 box ml BBraun/Inject - luer lock 1/100 box ml BBraun/Inject - luer lock 1/100 box ml BD/Plastipak - luer lock 1/60 box 20 ml Braun/Inject (*) has MEA tests performed on specific batches. A copy of the test certificate is provided with the orders of the specific lot numbers of the tested product. 50 ml BD/Plastipak Digital test tube heater A streamlined design with convenient user interface for quick and accurate temperature set. The warming blocks are designed to secure heat protection of the entire test tube. Ref Product Grant QBD 1, dry block heater for one warming block Grant QBD 2, dry block heater for two warming blocks Warming block for 10 x 14 ml test tubes / Ø 17 mm Warming block for 12 x 5 ml test tubes / Ø 12 mm info@.com 11

12 Gynetics embryo transfer catheters The Tulip pre-shaped tip is a thin embryo catheter for difficult transfers. The Tulip shapeable bulb at the distal end of the outer catheter enables easy and atraumatic entry through the cervical canal. Ref Product Packaging Tulip Catheter, pre-shaped 25/box Mandrel for Tulip Catheter 25/box Gamma irradiated, MEA and LAL tested, CE marked and single packed Thin atraumatic bulb tip eases introduction Centimeter marking for easy positioning Arrow marking for curve indication The Semtrac catheter is a soft double catheter with a soft inner catheter with a smooth and slick catheter tip. The catheter tip is designed so no cells attach to the catheter during transfer. Ref Product Length Semtrac W mm Semtrac W mm Semtrac W-180 Vision (echogenic) 180 mm Semtrac W-240 Vision (echogenic) 240 mm w/ Supported inner catheter Semtrac Set mm Semtrac Set 5 Vision (echogenic) 219 mm Gamma radiated and packed 25 catheters & 5 stylets per box The Emtrac Delphin is a soft one-piece single catheter with a smooth and slick catheter tip. The catheter tip is designed so no cells attach to the catheter during transfer. Ref Product Length Emtrac Delphin 210 mm Emtrac Delphin Vision (echogenic) 210 mm Gamma radiated and packed 25 catheters per box Tulip pre-shaped Semtrac Emtrac Delphin info@.com

13 Gynetics IUI catheters IUI Standard is an insemination catheter with side holes and standard soft tip. IUI Memo is an insemination catheter with side holes and a stiff shapeable tip facilitating the introduction of the catheter. Emtrac A is an insemination catheter with extra soft tip with an end hole eliminating dead space in the catheter. IUI Memo shapeable IUI Plus is an insemination catheter like the Emtrac A catheter but includes a stylet that can help form the catheter tip to any desirable shape. Ref Product IUI Standard IUI w/standard tip IUI Memo Memo w/shapeable tip Emtrac A w/soft round tip IUI Plus Plus w/stylet Gamma radiated and packed 25 catheters per box IUI / ET transfer syringes HSW Norm-Ject - MEA is a latex-, siliconeoil, PVC- and pyrogen-free 2-part syringe. has MEA tests performed on specific batches. A copy of the test certificate is provided with the orders of the specific lot numbers of the tested product. Codan Once is a very smooth syringe designed with a thin silicone ring at the tip of the cylinder piston. The design minimizes the contact area between silicone and the transfer media and thus significantly reduces particulate contamination. 1 ml HSW/Norm Ject 1 ml Once - luer 1 ml BD Plastipak Ref Product ml HSW Norm-Ject - MEA tested ml HSW Norm Ject ml Codan/Once - w. silicone ring ml BD Plastipak Single packed syringtes per box info@.com 13

14 Specimen containers & Male Factor Pack The MaleFactor Pack includes a sensitive, non-spermicidal polyurethane condom and carrying pouch with a patient ID label and it is intended for collection of semen samples through intercourse. R LAL MEA CE SSA ml with writing patch - LP 1/ ml with writing patch - LP 1/ ml sperm container - Oosafe CT01 1/ ml container w/pe lid - Falcon Male Factor Pack 1/10 1/ Screw cap container Polystyrene centrifuge tubes R LAL MEA CE SSA ml IVF centrifuge tube - Nunc / ml IVF centrifuge tube - Nunc / ml IVF centrifuge tube - Oosafe CT01 1/ ml centrifuge tube - Falcon / ml centrifuge tube - Falcon /500 + ProInsert The Nidacon ProInsert reduces the risk of contamination of the sperm pellet during sperm retrieval after a density gradient separation. The ProInsert comes as a kit and is a safe and easyto-use device. Shelf life 2 years. MEA tested ProInsert Kit 5 kits SpermRack One patient, one rack - both the centrifuge tubes and the sperm collection cup are kept together in the same rack. The SpermRack is made of stainless steel and can be washed and autoclaved. Ref Product SpermRack 41 (for 50/60 ml containers) SpermRack 62 (for 2 x 50 ml V tubes) SpermRack 61 (for 120 ml containers) SpermRack 61 SpermRack 41 SpermRack info@.com

15 Disposable cell counting slides The CellVision disposable counting slides are hygienic disposable slides with superior accuracy. Non-hygienic and time-consuming cleaning procedures are eliminated. The risk of exposure to potentially contaminated material is reduced drastically. CE marked. With counting grids These fill-wait-count disposable counting chambers are designed with a clear and bright built-in grid for manual counting. The grids are standard counting grids, and require no change to the counting protocol. The slides with 10² grid have an additional window for assessing sperm motility CellVision 10 µm - 10² grid (type Makler) 25 unit/box patent EP / US 7,016,033 patent EP / US 7,016,033 Cell Vision Cell Vision Cell Vision patent EP / US 7,016,033 wait 5 seconds start counting wait to settle - start counting A B A B A B add 5 µl add 5 µl add 5 µl add 5 µl add 25 µl add 25 µl 20 µm 10x10-grid Post Vasectomy Slide 20 micron Grid-volume = 1µl P : µm Neubauer improved P : Ref x10 grid (type Makler) Ref Post Vasectomy grid P : Ref Neubauer Improved grid CellVision 20 µm - 10² grid (type Makler) 25 unit/box CellVision 20 µm - Post Vasectomy grid 25 units/box CellVision 100 µm - Neubauer Improved grid 25 unit/box CellVision 100 µm - Bürker grid 25 unit/box CellVision 100 µm - Bürker-Turk grid 25 unit/box patent EP / US 7,016,033 Cell Vision wait 5 seconds start counting A B add 5 µl add 5 µl 20 µm Horizontal P : Ref Chamber horizontal CellVision 100 µm - Thoma grid 25 unit/box CellVision 200 µm - Fuchs Rosenthal grid 25 unit/box Cell Vision patent EP / US 7,016,033 wait to settle - start counting A B 1 20 µm add 5 µl P : Without grids The CellVision counting slide exists in two different designs without grid: with horizontal chambers and with vertical chambers that are optimized for CASA systems. Ref Chamber vertical (CASA) CellVision 16 µm - 2 chambers (horizontal) 25 unit/box CellVision 20 µm - 2 chambers (horizontal) 25 unit/box CellVision 20 µm - 2 chambers (vertical) 25 unit/box CellVision 20 µm - 4 chambers (horizontal) 25 unit/box CellVision 20 µm - 4 chambers (vertical) 25 unit/box CellVision 100 µm - 2 chambers (horizontal) 25 unit/box Reusable counting chambers The classic Makler chamber is 10 µm deep with a 10 x 10 grid for counting both undiluted and diluted sperm. Ref Product Makler counting chambers - standard Makler cover glass with grid Makler counting chambers - inverted info@.com 15

16 FertiPro density gradient system Solution of silane-coated silica particles in Earle s Balanced Salt Solutions (EBSS) HEPES-buffered ph in ambient conditions 7,20-7,60 Sterility SAL 10-3 Sil-Select Stock - A 100% stock solution that can be diluted with Ferticult Flushing medium for, a preparing density gradient system for the separation and purification of human sperm. CE marked. Shelf life: 2 years. Sil-Select Plus 45 / 90 - A two-step ready-to-use HEPESbuffered density gradient dilution of Sil-Select Stock, to 45% and 90%. CE marked. Shelf life: 18 months. Ferticult Flushing - A HEPES-buffered washing medium containing 0,4% human serum albumin. It is used for oocyte washing, embryo replacement, sperm injection in ICSI, sperm washing and swim-up techniques in human IVF. CE marked. Shelf life: 18 months Sil-Select Stock 1x100 ml Sil-Select Stock 1x500 ml Sil-Select Plus 45/90 2x20 ml Sil-Select Plus 45/90 2x50 ml Sil-Select Plus 45/90 2x100 ml Sil-Select Plus 80 1x100 ml Sil-Select Plus 45/90 - with gentamicin & phenol red 2x500 ml FertiCult Flushing medium 5x20 ml FertiCult Flushing medium 5x50 ml FertiCult Flushing medium 3x100 ml FertiCult Flushing medium - with gentamicin & phenol red FertiCult Flushing medium - with phenol red 3x100 ml 3x100 ml info@.com

17 Nidacon gradient system Solution of silane-coated silica colloid in an isotonic salt solution HEPES acts as a buffer and antioxidant Glucose as a primary energy substrate No preservatives, no unstable ingredients,...and no phenol red PureSperm A 100% stock solution that is optimized for the preparation of density gradients for the separation and purification of human sperm, and can be diluted with PureSperm Buffer. CE marked. Shelf life: 2 years. PureSperm 40 - PureSperm 80 - Ready-to-use HEPESbuffered density gradient solutions, 40% and 80%, for use in ambient conditions. CE marked. Shelf life: 2 years. PureSperm Buffer - A solution designed for diluting PureSperm 100. The optimized formulation of PureSperm Buffer is designed to maximize sperm survival during gradient centrifugation. CE marked. Shelf life: 2 years. PureSperm Wash - It is optimized for washing the sperm pellet recovered from density gradient preparation. PureSperm Wash contains human serum albumin. It contains no coloring agents or preservatives. Shelf life: 1 year PureSperm 40/80 2 x 20 ml PureSperm ml PureSperm ml PureSperm ml PureSperm ml PureSperm ml PureSperm Buffer 100 ml PureSperm Wash 100 ml PureSperm Wash 2 x 20 ml info@.com 17

18 Detection of anti-sperm antibodies With SpermMar Iga & IgG To screen for immunological infertility, it is sufficient to search for IgG antibodies on spermatozoa. If more than 40% of motile spermatozoa present anti-sperm antibodies of the IgG class, complementary testing for IgA antibodies is advisable. Shelf life: SpermMar IgA 12 months/igg 18 months at 2-8 C. Assessment of sperm morphology With Spermac Stain The Spermac Stain method is simple and perfectly adequate for the detailed investigation of morphology of all parts of the spermatozoa. It is a four-step staining procedure with results obtained within 15 minutes. Shelf life: 3 years stored between 4 C and 25 C. Quantifying live spermatozoa With VitalScreen The test uses the eosin-nigrosin staining technique to establish the percentage of live spermatozoa. To be used for samples with 50% or more immotile spermatozoa. Shelf life:12 months stored between 4 C and 25 C. Hypo-osmotic swelling test Sperm vitality test The test is based on the semi-permeability of the intact cell membrane, which causes spermatozoa to swell under hypo-osmotic conditions, when an influx of water results in an expansion of the cell volume. It should not be used as a sperm function test but as an optional/additional vitality test, providing additional information on the integrity and compliance of the cell membrane of the sperm tail. Shelf life: 12 months stored at 2-8 C. a) normal spermatozoon, b-g) various types of tail changes due to swelling SpermMar IgA single (reagent) 50 tests SpermMar IgA complete kit 50 tests SpermMar IgG single (reagent) 50 tests SpermMar IgG complete kit 50 tests SpermMar IgG positive control 50 tests SpermMar IgG negative control 50 tests Spermac Stain 4 x 50 ml Spermac Stain 4 x 250 ml VitalScreen 200 tests Hypo-osmotic swelling test 9 tests info@.com

19 Determination of the DNA fragmentation HaloSperm determines DNA fragmentation in sperm cells. Halosperm is fast, easy to use, highly reproducible and requires only the use of a bright field microscope. This additional parameter of semen quality allows clinicians to (1) distinguish which couples are suitable for IUI, (2) assess the quality of semen samples or donors for suitability, (3) assess the efficacy of medical interventions or treatment of infectious diseases, (4) provide answers to cases of unexplained infertility, ART failure or repeated abortions. HaloSperm G2 will give the same results as the HaloSperm kit but instead requires just a few drops of Halosperm G2. It is easier to use and the big advantage is a notable reduction of the smell derived from the Lysis solution. Halosperm G2 also includes a staining kit for bright field microscopy. Dyn-HaloSperm determines DNA fragmentation in sperm cells just like the Halosperm test and it allows the study of sperm DNA fragmentation over time. This allows you to select the optimal moment and best reproductive technique to carry out an ART cycle HaloSperm test 10 tests Dyn-HaloSperm test 5 tests HaloSperm G2 test 10 tests Staining trays - disposable 5 units Diff Quick Staining Kit - Azure B & Eosin 2 x 30 ml Determination of oxidative stress OxiSperm an easy method for the assessment of the presence of oxidative stress in neat ejaculated sperm samples. The test uses a Reactive Gel that has the capacity to change color. The intensity of the color is related to the level of oxidative stress in the sample. The test is performed in 45 minutes OxiSperm 20 tests info@.com 19

20 The perfect sperm handling pipette tips The MEA tested ART Tip (ART ) is a self-sealing filter tip that protects pipettes from carry-over contamination by not allowing liquids or aerosols to come into contact with the pipette cone. The extra thin and long ART tips enables you to reach the bottom of your 11 ml and 15 ml centrifuge tubes with very little chance that your pipette will come into contact with the inside of your sample tube. 10,80 cm 12,01 cm 9,10 cm The combination of the protecting filter and the extra tip length virtually eliminates both the risk of carry-over contamination and the need for cleaning or replacing your pipette ART tip 180 µl ext MEA 8 x 96 rack ART tip 1000 µl ext MEA 8 x 100 rack Short ergonomic pipettes The Finnpipette Short µl is 5 cm shorter than the Eppendorf Research plus pipette. It incorporates color-coded volume adjustment knobs, patented super blow-out technology, lightweight and a variety of volume ranges. The IVFpipette is designed to make it possible to pipette small volumes. This is possible because the IVFpipette has a tip cone that fits the extended 1000 µl tips. The tip cone of all IVFpipettes is designed to fit 1000 µl tips which makes it possible to use the extended 1000 µl filtertip for pipetting µl. Ref Product IVFpipette µl - yellow Finnpipette Short µl - blue Same tip 1000 µl different volumes µl µl info@.com

21 MEA tested pipette tips... with filter Aerosol Resistant Tip (ART ) is a self-sealing filter tip which protects pipettes from carry-over contamination by not allowing liquids or aerosols to come into contact with the pipette. Consequently, the ART filter tips will drastically reduce both the risk of carry-over contamination from one sample to another and the need for cleaning or replacing your pipette. The ART tips are sterilized, mouse embryo tested, and certified free of RNase, DNase, ATP and pyrogens µl µl µl µl µl µl ART tip 10 µl MEA - 96 rack 960 units ART tip 20 µl MEA (G) - 96 rack 960 units ART tip 20 µl MEA (y) - 96 rack 960 units ART tip 100 µl MEA - 96 rack 960 units ART tip 180 µl ext MEA - 96 rack 768 units ART tip 200 µl MEA - 96 rack 960 units µl ART tip 300 µl MEA - 96 rack 960 units ART tip µl ext MEA rack 800 units µl Finnpipette adjustable The Finnpipette F1 is a new very light pipetting action that requires just a small amount of effort. The handle and the dispensing button of the Finnpipette F1 are made of an anti-microbial polymer containing silver ions as the active ingredient. The adjustable finger rest that can be adjusted 120 to the most ergonomic and comfortable position for pipetting and tip ejection. Adjustable finger rest Ref Product Finnpipette F µl P Finnpipette F µl Y Finnpipette F µl T Finnpipette F µl Y Finnpipette F µl T Finnpipette F µl Y Finnpipette F µl Y Finnpipette F µl Y Finnpipette F µl O Finnpipette F µl B Soft touch tip ejection info@.com 21

22 Eppendorf adjustable pipettes The Eppendorf Research Plus pipette is an ultra light and fully autoclavable pipette. It has a spring loaded tip cone, is durable, has perfect balance and requires minimal user effort. Ref Product Research Plus adjust. DG 0,1-2,5 µl Research Plus adjust. G 0,5-10 µl Research Plus adjust. G 2-20 µl Research Plus adjust. Y 2-20 µl Research Plus adjust µl Research Plus adjust µl Research Plus adjust µl Research Plus adjust µl The Pipette Stand is an elegant and simple stand that takes up minimal space inside the LAF cabinet. In IVF the three-position stand is enough for most work stations. Ref Product Pipette stand gray - 3-pos Pipette stand gray - 6-pos Eppendorf pipette tips MEA tested eptips eptips Biopur µm MEA 480 units Standard eptips eptips 0,1-20 µl - Biopur single packed 100 units eptips µl - Biopur single packed 100 units eptips µl - Biopur single packed 100 units eptips 0,1-20 µl - Biopur 96 rack 480 units eptips µl - Biopur 96 rack 480 units eptips µl - Biopur 96 rack 480 units eptips µl - Biopur 96 rack 480 units eptips µl - Bulk packed non sterile 1000 units eptips µl - Bulk packed non sterile 1000 units Dualfiltered eptips ep Dualfilter Tips 0,1-10 µm M - 96 rack 960 units ep Dualfilter Tips 0,5-20 µm L - 96 rack 960 units ep Dualfilter Tips 2-20 µm - 96 rack 960 units ep Dualfilter Tips µm - 96 rack 960 units ep Dualfilter Tips µm - 96 rack 960 units ep Dualfilter Tips µm - 96 rack 960 units ep Dualfilter Tips µm - 96 rack 960 units info@.com

23 IVF handling pipettes For handling oocytes and embryos. The tip is crystal clear PET which is non-breakable and does not scratch dishes. Gamma sterilized, LAL tested, mouse embryo tested and CE marked Handling pipette 55 mm - single pack 50 units Handling pipette 55 mm - 10 pack 250 units Handling pipette 95 mm - single pack 50/box Oocyte pick up Denudation Embryo handling IVF Glass pasteur pipettes Sterile pasteur pipettes of borosilicate glass and soda glass prepared for IVF use. The entire pipette, including the synthetic fiber plug, is gamma sterilized, mouse embryo tested and CE marked as a class 2a Medical Device under the EU medical directive. The pipettes are packed 100 units per box packed in bags of 5 units IVF Pasteur Pipette, 150 mm soda 100 units IVF Pasteur Pipette, 230 mm soda 100 units IVF Pasteur Pipette, 150 mm soda - plugged 100 units IVF Pasteur Pipette, 230 mm soda - plugged 100 units IVF Pasteur Pipette, 150 mm borosilicate 100 units IVF Pasteur Pipette 230 mm borosilicate 100 units IVF Pasteur Pipette, 150 mm borosilicate - plugged 100 units IVF Pasteur Pipette, 230 mm borosilicate - plugged 100 units Pipette Bulb 10 units Plastic pasteur pipettes ml plastic pasteur pipette - single packed 1/ ml plastic pasteur pipette - multi packed 20/ ml plastic pasteur pipette - non-sterile 500 Plastic pasteur pipettes info@.com 23

24 Pipette controller The Capp Tempo Pipette Controller is a reliable lightweight and ergonomic pipette with steel pistons. Quick and precise manual pipetting. Ref Product CappTempo pipette controller, Blue CappTempo pipette controller, Red CappTempo pipette controller, Yellow CappTempo pipette controller, Green CappTempo charging stand CappTempo disposable 0,2 µm filter (10 units) Serological pipettes ml Serological pipette - Nunc units/box ml Serological pipette - Nunc units/box ml Serological pipette - Nunc units/box ml Serological pipette - Nunc units/box ml Serological pipette - Nunc units/box ml Serological pipette - Nunc units/box ml Serological pipette - LP Italiana 1000 units/box ml Serological pipette - LP Italiana 1000 units/box ml Serological pipette - LP Italiana 500 units/box ml Serological pipette - LP Italiana 500 units/box ml Serological pipette - LP Italiana 200 units/box Media flasks The EasyFlask is ergonomically designed with a conveniently large footprint and a short wide angled neck for easy access/ filling EasYFlask TC 25cc/70 ml - v/c cap, units/box EasYFlask TC 25cc/70 ml - f cap, units/box EasYFlask 70 ml - v/c cap, units/box EasYFlask TC 75cc/260 ml - v/c cap, units/box EasYFlask TC 75cc/260 ml - f cap, units/box Filter cap Vent close cap info@.com

25 Eppendorf Multipette Eppendorf Multipette Xstream is an electronic pipette with automatic aspiration and repetitive dispensing, without the need to refill. It is perfect for dispensing droplets in IVF. Time saving and contamination-free dispensing using the positive displacement principle. Eppendorf Multipette Plus is a pipette for manual repetitive dispensing, without the need to refill. It is perfect for dispensing droplets in IVF. Time saving and contamination-free dispensing using the positive displacement principle. Ref Product Eppendorf Multipette Xstream Multipette Xstream Wall Mount Multipette Xstream Charging Stand Eppendorf Multipette Plus Eppendorf CombiTips Combitips advanced Biopur - 0,5 ml 100 units Combitips advanced Biopur - 1,0 ml 100 units Combitips advanced Biopur - 2,5 ml 100 units Combitips advanced Biopur - 5 ml 100 units Combitips advanced Biopur - 10 ml 100 units Combitips advanced Biopur - 25 ml 25 units Combitips advanced Biopur - 50 ml 25 units Standard dishes - Falcon Standard dishes - Nunc x10mm EasyGrip TC dish - Falcon / x10 mm EasyGrip dish - Falcon / x10 mm EasyGrip dish - Falcon S 20/ x15 mm dish - Falcon / x15 mm EasyGrip dish - Falcon / x15 mm EasyGrip TC dish - Falcon / x15 mm Primaria TC dish - Falcon / x15 mm petri dish - Falcon / well dish - Nunc / well TC dish (sp) - Nunc / well TC dish (mp) - Nunc / x10mm TC dish, vent - Nunc / x15mm TC dish, vent - Nunc / x17mm TC dish, vent - Nunc / x21mm TC dish, vent - Nunc / x15mm petri dish - Nunc / info@.com 25

26 IVF Petri dishes MEA CE mm IVF petri dish - Nunc hydrophobic, for microdrops 10/ x15 mm IVF dish - Oosafe TF10 20/ x15 mm IVF dish - Oosafe ST10 10/ x15 mm IVF dish - Oosafe ST01 10/ mm IVF petri dish - Nunc hydrophobic, for microdrops 10/ mm IVF dish - Falcon / x20 mm IVF dish - Oosafe HD10 10/ mm IVF petri dish - Nunc / * MEA tested, HSSA and endotoxin tested. GPS dishes The Embryo GPS dish has 8 outer wells for 50 μl and 3 inner wells for 100 μl. Embryo culture becomes simpler and safer and the variety of wells gives you both consistency and flexibility in single or group culture. The Universal GPS dish has 8 outer wells for 100 μl and 2 inner wells for 150 μl. The larger wells give you increased flexibility in the lab. MEA CE Embryo GPS dish 10/ Universal GPS dish 10/ Glass bottom dishes Thin optical quality glass bottom dishes for high-end microscopy. Ideal for spindle imaging and applications which require low background scattering of light and no bi-refringence /40x7 mm WillCo-dish - sleeve of /box Lid /40x7 mm WillCo-dish - single pack 120/box /30x7 mm WillCo-dish - sleeve of /box /30x7 mm WillCo-dish - single pack 120/box Safe-grip ring Well depth 1 mm Dish /22x10 mm WillCo-dish - sleeve of /box /22x10mm WillCo-dish - single pack 120/box Optical glass bottom info@.com

27 IVF 4-well dishes Nunc, Falcon and Oosafe IVF dishes are tested and certified for human use. Each batch is tested for endotoxins, is certified non-pyrogenic and 1-cell MEA tested. MEA CE well IVF dish - Oosafe FW04 4/ well IVF dish - Nunc / well IVF dish - Falcon / * MEA tested, HSSA and endotoxin tested. Micromanipulation dishes MEA CE IVF ICSI dish 50x9 mm - Oosafe IC01* 1/ IVF ICSI dish 50x9 mm - Oosafe IC01* 1/ IVF ICSI dish 50x9 mm - Nunc / IVF ICSI dish 50x9 mm - Falcon / x9 mm dish - Falcon MEA ** 20/ x9 mm dish Falcon /500 * MEA tested, HSSA and endotoxin tested. ** has samples of specific batches of dishes MEA tested. A copy of the test certificate is provided with the orders of the specific lot numbers of the tested product. IVF center well dishes MEA CE IVF Center well dish - Oosafe CW03 10/ IVF Center well dish - Oosafe CW02 1/ IVF Center-well dish - Nunc / IVF Center-well dish - Falcon / * MEA tested, HSSA and endotoxin tested. DishRack With the DishRack you always have control of the dishes while airing out or storing inside the laminar cabinet. The piles of dishes will never tip over. Holds 60 mm and 55 mm dishes. Ref Product DishRack info@.com 27

28 Gain Culture Medium The Gain medium is a ready-to-use cell culture media for use in human in vitro fertilization. It is developed for use during fertilization and embryo culture up to expanded blastocyst stage. The media contain 0.35% human serum albumin (EMA, Ph Eur, USP, FDA approved), gentamicin and low concentrations of phenol red (ph indicator). Shelf life is 12 months Gain ES medium - 10 ml 1 x 10 ml Gain BL medium - 10 ml 1 x 10 ml Light Paraffin Oil For overlay during micromanipulation or culture NidOil from Nidacon is a pre-washed, pharmaceutical grade, light paraffin oil to be used in IVF. CE marked and bottled in UV protective packaging. Shelf life: 24 months Nidacon mineral oil ml 1 x 100 ml Nidacon mineral oil ml 1 x 300 ml FertiCult Mineral Oil is a pre-washed, pharmaceutical grade, light paraffin oil to be used in IVF. CE marked. Shelf life: 18 months FertiCult mineral oil - 50 ml 1 x 50 ml FertiCult mineral oil ml 1 x 100 ml FertiCult mineral oil ml 1 x 500 ml Ultra pure water The ultra pure water is purified and tested according to the specifications for highly purified water as described in the European Pharmacopoeia. Supplied with a certificate of analysis. Shelf life 12 months Ref Product Ultra pure water ML info@.com

29 For slowing sperm in ICSI FertiCult PVP 10%. PVP (polyvinylpyrrolidone) in HEPES buffered FertiCult Flushing medium is used in ICSI procedures. Shelf life: 9 months. Ref Product FertiCult PVP 10%, 1 x 1 ml FertiCult PVP 10%, 5 x 0,2 ml Nidacon SpermCatch is a natural alternative for slowing sperm for ICSI. It contains only substances found in the mammalian reproductive tract; human serum albumin (hsa) but no PVP or antibiotics. Shelf-life: 1 year. Ref Product SpermCatch μl For testicular tissue and immotile sperm Collagenase is a ready-to-use medium that helps degrade testicular tissue to release sperm cells. Reduces the time spent isolating spermatozoa. Shelf life: 9 months. Ref Product Collagnase - 3 ml Sperm extraction kit. Specially designed pestle for disrupting biopsies of the testis (TESE) in microtubes with a gentle manual back-and-forth rotation. The pestles are wrapped individually, RNase, DNase and Pyrogen-free, and packed in a set with single packed 1,5 ml Biopur Eppendorf tubes. Ref Product Sperm extraction kit - 25 sets SpermMobil is a ready-to-use medium for activation of immotile or poorly motile sperm from ejaculates and testicular biopsies. Shelf life: 9 months. Ref Product SpermMobil - 1 ml For oocyte activation Cult-Active is a ready-touse calcium ionophore for activation of oocytes from patients with failed or low fertilization in previous cycles. Shelf life: 6 months. Ref Product Cult-Active 1 ml info@.com 29

30 Strip-ID flexible pipettes The Strip-ID pipette is a flexible and unbreakable microcapillary used for handling oocytes and embryos during IVF procedures. The Strip-ID pipette is crystal clear, sterile, MEA tested. It is made of polycarbonate which does not scratch culture dishes. Fits most commonly used micropipette holders Strip-ID pipette /tube - 50 box Strip-ID pipette /tube - 50 box Strip-ID pipette /tube - 50 box Strip-ID pipette /tube - 50 box Strip-ID pipette /tube - 50 box Strip-ID pipette /tube - 50 box Strip-ID pipette /tube - 50 box Strip-ID pipette /tube - 50 box Strip-ID pipette /tube - 50 box Synga glass micropipettes Practical borosilicate glass micropipettes with a silicone bulb and an ergonomic aluminum pipette handle. The Synga pipettes are single packed inside glass tubes with 5 glass tubes per bag and 20 pipettes per box. Sterile and CE marked Synga Denuding pipette μm 20 units/box Synga Denuding pipette μm 20 units/box Synga Denuding pipette μm 20 units/box Synga Manipulating pipette μm 20 units/box Synga Manipulating pipette μm 20 units/box Synga Pipette Handle 1 unit 130/140/150 µm (non-polished) denuding oocyte Color identification of pipette sizes For denuding oocytes FertiCult Hyaluronidase is a solution containing 80 IU/mL hyaluronidase in FertiCult Flushing medium. Shelf life - 6 months. Ref Product FertiCult Hyaluronidase, 1 x 10 ml FertiCult Hyaluronidase, 5 x 1 ml info@.com

31 Micropipettes from The Pipette Company (TPC) For micromanipulation of gametes and embryos. Gamma radiated, MEA tested and CE marked. Packed in boxes of 10 units. Product Tip length Od/Id Ref 30 Ref 35 Injection pipettes Injection pipette w/spike 1,0 mm 6,5/5,0 µm Injection pipette w/spike - extra rigid 1,0 mm 6,5/5,0 µm Injection pipette w/spike - thin 0,6 mm 5,0/4,0 µm Injection pipette w/spike - large (biopsies) 1,0 mm 8,0/6,0 µm Injection pipette without spike - 21 bevel 0,6 mm 6,5/4,5 µm Holding pipettes Holding pipette 1,0 mm 120/25 µm Holding pipette - thin 1,0 mm 100/20 µm Holding pipette - large 1,0 mm 120/30 µm Holding pipette - extra thin 1,0 mm 100/15 µm Hatching pipettes Hatching pipette 1,0 mm 12/9,0 µm Zona cutting pipettes (PZD) Zona Cutting pipette 1,0 mm 2,0 µm Injection pipette w/ spike Injection pipette without spike Holding pipette Hatching pipette Zona Cutting pipette Biopsy pipettes Biopsy pipette - bevel 40 1,0 mm 30/23 µm Biopsy pipette - straight 90 1,0 mm 27/21 µm Biopsy pipette w/ bevel Mouth pipette set A simple mouth pipette making it possible to pipette without any risk of contact with what you are pipetting. It consists of a 100% non-permeable but flexible membrane connector and an ergonomic flat mouth piece. The mouth pipette set is to be used with glass pasteur pipettes or micropipettes For micro-pipettes a separate adaptor is available Mouth pipette set 1 unit Separate parts: Red mouth piece 25/bag Flexible membrane connector 6/bag Micropipette adaptor 1 unit info@.com 31

32 VitriFreeze-ES by FertiPro VitriFreeze-ES is a three-step medium based on % DMSO and ethylene glycol. The gradual increase in osmolality prevents osmotic shock to the embryo and the final high concentration is an advantage when using closed devices. CE marked according to the European Medical Device Directive. Shelf life: 12 months VitriFreeze-ES Kit 4 procedures VitriThaw-ES Kit 4 procedures Oocyte vitrification - part of the 5% solution needs to be diluted with pre-incubation media, to 2,5% and 1,25%, in order to follow a 1,25 to 2,5 to 5 to 10 to 20% protocol of DMSO and ethylene glycol. This allows for an even more gradual increase in osmolality, which is essential in order to prevent osmotic shock when performing oocyte vitrification. Early cleavage embryo vitrification For this purpose the VitriFreeze-ES is a ready-to-use kit. Stage Preincubation media 1,25/1,25% DMSO/EG 2,5/2,5% DMSO/EG 5/5% DMSO/EG 10/10% DMSO/EG 20/20% DMSO/EG Oocyte 2 min 2 min 2 min 4 min 6 min 60 sec Protocol for closed device vitrification as recommended by Pierre Vanderzwalmen. Alternative protocol for open device vitrification is also available. Stage Preincubation media 5/5% DMSO/EG 10/10% DMSO/EG 20/20% DMSO/EG Zygote to 2-cell 2 min 5-10 min 5 min 60 sec 4-cell to early blc 2 min 5-7 min 4 min sec Expanded blastocyst 2 min 5-7 min 4 min sec Protocol for closed device vitrification as recommended by Pierre Vanderzwalmen. Alternative protocol for open device vitrification is also available. Blastocyst vitrification For this purpose the VitriFreeze-ES is a ready-to-use kit. Warming procedure For oocytes, early cleavage embryos and blastocyst warming, the VitriThaw-ES is a ready-to-use kit. Stage Thaw 1 1,0 M Thaw 2 0,75 M Thaw 3 0,5 M Thaw 4 0,25 M Thaw 5 0,125 M Oocyte 60 sec 60 sec 3 min 3 min 2 min Zygote to blastocyst 60 sec 60 sec 60 sec 2 min 2 min Protocols as recommended by Pierre Vanderzwalmen VitriBlast by Nidacon VitriBlast by Nidacon is based on a two-step 7,5 to 15% concentration of DMSO and ethylene glycol kit. The cryoprotectants are supplemented before the vitrification procedure begins. One kit of VitriBlast and ThermoBlast can vitrify and warm for 10 patients. Shelf life: 12 months VitriBlast Kit 10 procedures ThermoBlast Kit 10 procedures info@.com

33 High security vitrification straw A straightforward system with a simple load-seal-cool handling procedure that makes it a highly efficient and very fast vitrification device. CE marked and gamma sterilized. 100% safe and closed - The inner straw is loaded and placed inside an ultra-thin outer straw, and the outer straw is sealed before it is vitrified in liquid nitrogen. Superior warming rates - The vitrification straws are opened while immersed in liquid nitrogen. The inner straw is removed and dipped into the warming solution immediately. Color coded - The inner straws are color-coded with six different colors making identification easy when stored in liquid nitrogen tanks. Outer straw Inner straw Handling rod Space efficient - The CBS vitrification straw is a very thin straw making it possible to store up to 15 straws in a standard 13 mm visotube HSV Vitrification Kit - red 4 x 1 unit HSV Vitrification Kit - white 4 x 1 unit HSV Vitrification Kit - yellow 4 x 1 unit HSV Vitrification Kit - pink 4 x 1 unit HSV Vitrification Kit - blue 4 x 1 unit HSV Vitrification Kit - green 4 x 1 unit x x Place embryo here Straw Cutter The HSV Straw Cutter is the perfect tool for simple and easy opening of the HSV vitrification straws. Hold the straw partly immersed in liquid nitrogen and gently remove the top of the outer straw using the straw cutter, with no risk of damaging the inner straw. With the top of the outer straw cut, the inner straw can be removed and placed in the warming solution immediately. Ref Product HSV Straw Cutter info@.com 33

34 High security sperm straws The 0,5 ml high security sperm straw has a colored plug at the end and the working volume is 0,5 ml. The 0,3 ml high security sperm straw has two compartments: the working volume is 0,3 ml and a second compartment for an internal colored ID stick. The ID stick can be labelled with the patient name or donor ID High security sperm straw 0,3 ml 4x5 units High security sperm straw 0,3 ml 5x20 units High security sperm straw 0,5 ml white 4x5 units High security sperm straw 0,5 ml yellow 5x20 units High security sperm straw 0,5 ml green 5x20 units High security sperm straw 0,5 ml blue 5x20 units High security sperm straw 0,5 ml white 5x20 units High security sperm straw 0,5 ml red 5x20 units High security sperm straw 0,5 ml orange 5x20 units High security sperm straw 0,5 ml grey 5x20 units Product/Color (bags of 10 units) Yellow Green Blue White Red Orange Weighted ID sticks - 30 mm SpermFreeze by FertiPro SpermFreeze SSP is designed for freezing raw semen, purified sperm, and for testicular biopsies. The sperm sample is diluted 1 part media to 3 parts sperm. The medium contains HSA, but no milk or egg yolk with possible avian contaminants, and comes in handy 1 ml ampules. Shelf life: 18 months SpermFreeze SSP 1:3-5 ml 5x1 ml SpermFreeze SSP 1:3-20 ml 1x20 ml SpermFreeze SSP 1:3-125 ml 1x125 ml SpermFreeze is similar to the SpermFreeze SSP but less concentrated. The sperm sample is diluted 0,7 part media to 1 part sperm. Contains HSA, but no milk or egg yolk with possible avian contaminants. Shelf life: 18 months SpermFreeze 2:3-100 ml 5x20 ml SpermFreeze 2:3-125 ml 25x5 ml info@.com

35 High security straw for sperm & embryos The NEW 0,3 ml high security straw for sperm and embryos is a single packed 0,3 ml high security straw with a cotton-powder-cotton plug. The new straw is similar to the 0,3 ml high security sperm straw but single packed. The transparent filling tip is ordered separately (please see below) and the matching ID stick is the 30 mm ID stick (see page 34). New High security straw 0,3 ml 20x1 unit High security embryo straws The high security embryo straw is a 100% hermetically sealable straw made of ionomeric resin. The straw is CE marked and comes with a pre-mounted clear filling tip and a hydrophobic plug High security embryo straw 0,3 ml 20x1 unit The colored ID sticks for embryo straws are 40 mm long. Gamma sterilized, 10 units per bag. Color Yellow Green Blue White Red Orange Weighted ID sticks 40 mm Filling the high security straws The high security straws have to be filled through a specially designed yellow filling tip, because the straw will not seal correctly if it is wet on the inside end of the straw. 1. Connect a filling tip to the open end of the straw 2. Connect a syringe and syringe connector to the other...end of the straw 3. Aspirate the sample through the tip with the syringe Filling tip, yellow - for sperm straws 1 x 10 units Filling tip transparent 100 x 1 unit Syringe connector 2 x 5 units info@.com 35

36 Classic 0,25 cc embryo straw CE marked and gamma sterilized PETG straws. The soft straws are preferable when closing the straws with ID rods. The rigid straws can to some extent be sealed with a standard heat sealer - although the seal will crack when immersed in liquid nitrogen. The 91 mm straw is the recommended straw length when using the Cryologic freezer and closing the straws with ID rods Classic embryo straw 91 mm, rigid 4x5 units Classic embryo straw mm, rigid 4x5 units Classic embryo straw 91 mm, soft 4x5 units Classic embryo straw 133 mm, soft 4x5 units ID rods - for closing soft 91 mm classic embryo straws. Sterilized, CE marked and packed in kits of 4x5 units. Color Dark Blue Light Yellow Light Blue Light Green Red Orange White Grey Pink Purple Ref Short ID rods - for closing soft 133 mm classic embryo straws. Sterilized, CE marked and packed in kits of 4x5 units Short ID rod for 133 mm embryo straw 4x5 units Classic sperm straw Classic PETG sperm straws with cotton plug. CE marked and gamma sterilized Classic straw 133 mm/0,5 ml - transparent 100 units Classic straw 133 mm/0,25 ml - transparent 100 units Micro aspirator The Micro aspirator is the perfect tool for loading and flushing cryopreservation straws. Its elastic adaptor fits almost any diameter of straws. The working angle can be easily adjusted. Ref Product Micro aspirator micro-classic unit Micro aspirator tube with adaptor 3 units info@.com

37 High Security Tube The CBS High Security Tube is a 100 % hermetically sealable tube made of cryo-resistant resin. It is validated as leak-proof and shatter-proof in all cryogenic temperatures including liquid nitrogen. When fully sealed the risk of cross-contamination of the specimen is eliminated. The CBS High Security Tube is compatible with common CryoCanes as well as cryostorage racks and boxes. The useable volume is 1,2 ml and the tube is CE marked Easy to open High Security Tube x 1 unit High Security Tube units High Security Tube (non-sterile) units Color Insert for HS Tube - assorted 500 units Autoclavable scissors for HS Tube 1 unit SYMS II Sealer Automatic high security sealer designed for the sealing of High Security tubes and straws. Tube holder Easy-to-use touch screen interface with a simple function for selecting between tubes and straws. The position of the tube or straw is autodetected and the sealing is performed automatically. Information about the sealing process, maintenance and alarms is communicated through the touch screen. Ref Product SYMS II high security sealer SYMS sealer for high security straws The SYMS sealer is designed for sealing of the CBS high security embryo, sperm and vitrification straws. The sealer is electronically operated by a push button or by foot pedal. Ref Product SYMS sealer for high security straws info@.com 37

38 Cryo-Gloves & Cryo-Apron Both Cryo-Gloves and Cryo-Apron are designed to keep you safe and comfortable when working in ultra-cold environments. They have a flexible, multi-layered insulated construction that provides maximum thermal protection, yet offers comfort, flexibility, and dexterity so you can perform tasks effectively and safely. Ref Product Cryo-Gloves Mid-Arm, S Cryo-Gloves Mid-Arm, M Cryo-Gloves Mid-Arm, L Cryo-Gloves Mid-Arm, XL Cryo-Apron Cryo face shield CryoGoggle Nunc CryoTubes and ccessories Ergonomically designed CryoTubes that are easy to open. The CryoTubes are designed with internal thread and are intended for transportation and storage of biological material. CryoTube color codes fit neatly into the caps of Nunc CryoTubes for easy color identification of your samples. The CryoTube rack allows for one-handed opening and closing of Nunc CryoTubes, thanks to the tube grip in the bottom of each hole of the rack. The rack is autoclavable and holds 40 tubes IVF cryo tube 1,8 ml units Cryo Tube 1,0 ml S 500 units Cryo Tube 1,8 ml S 450 units Cryo Tube 3,6 ml S 400 units Cryo Tube 4,5 ml S 300 units CryoTube color code - 10 colors 500 units CryoTube Rack for 40 tubes 1 unit info@.com

39 Cryo-cassettes The straws are safely secured inside the cassettes preventing the straws from floating inside the storage tank. Part of the cassette is a convenient lifter making it easy to remove or insert a straw. Packing 10 units. Color Triangular 140 mm Flat 280 mm Triangular 280 mm Blue Green Red Yellow Beige White CryoCane The CryoCane is a storage device to be placed into the canister of the cryotank and it is designed to hold Cryotubes as well as 12 and 13 mm visotubes. CryoCane sleeve The 275 mm long clear plastic sleeve encloses a CryoCane for extra security during handling and storage. Allows for quick location of empty spaces in the cane and easy identification of a particular vial or vials without removing the sleeve. CryoCane tabs Unique identification tabs make it easy to keep track of your inventory of CryoCanes. The tabs can be marked with colored cryopens and they remain firmly in place during storage in liquid nitrogen CryoCane for Nunc tubes 50 units CryoCane tabs - White 100 units CryoCane sleeve 100 units info@.com 39

40 Goblets and Visotubes The goblet is a plastic cup holding the colored visotubes inside the canister of the cryotank. Convenient goblet lifters and lids for the goblets are available for the 65 mm goblet Goblet, Ø 35 mm 10 units Goblet, Ø 65 mm 10 units Lid for Ø 65 mm Goblet 10 units Lifter for Ø 65 mm Goblet 1 unit Goblet Lifter Ref The visotubes come in a classic round, polygonal, hexagonal and a triangular model designed for Daisy Goblets. Neither version is perforated so that the liquid nitrogen remains around the straws if the goblet is temporarily removed from the storage tank. Item Specification Polygonal Visotube Hexagonal Visotube Round Visotube Ø 7,1 mm Round Visotube Ø 9,2 mm Round Visotube Ø 10 mm Round Visotube Ø 12 mm Round Visotube Ø 13 mm Clear/White Red Green Blue Yellow Orange Purple Packing 50 units 50 units 100 units 100 units 100 units 100 units 100 units Assorted Packing 60 units 70 units 60 units 60 units 60 units 60 units 60 units info@.com

41 Cryo storage tanks Designed to maximize storage capacity for applications that involve larger quantities of straws. The choice between the different models depends on your specific requirements. Ref Product Dimensions Capacity Canisters Storage tank HCL 12 H 48 cm/ø 40 cm 12 L 6 (127 mm/ø 70 mm) Storage tank XT 20 H 65 cm/ø 39 cm 21 L 6 (280 mm/ø 38 mm) Storage tank HC 20 H 62 cm/ø 39 cm 20 L 6 (280 mm/ø 70 mm) Storage tank HC 34 H 67 cm/ø 48 cm 34 L 6 (280 mm/ø 70 mm) Storage tank HC 35 H 68 cm/ø 48 cm 35 L 10 (280 mm/ø 70 mm) Canisters 70 x 279 mm 280 mm/ø 70 mm Roller Base 12/20 H 11 cm for HCL-12/HC-20/XT-20/LD Roller Base 34/35 H 11 cm for HC-34/HC-35/LD-50 Liquid nitrogen tanks The Classic 25 is a very practical LN 2 storage tank as the design makes it ideal for pouring liquid nitrogen. Ref Product Dimensions Capacity LN 2 tank LD 25 classic H 58 cm/ø 39 cm 25 L LN 2 tank LD 25 H 65 cm/ø 39 cm 25 L LN 2 tank LD 35 H 67 cm/ø 48 cm 35 L Liquid withdrawal device Tipping Stand 25 for LD-25/LD-25 Classic Daisy Goblets and Visotubes The Daisy goblet is a pre-configured 65 mm goblet with perforated bottom. It is configured with 1 round and 11 triangular visotubes Daisy Goblet, Ø 65 mm w/lid* 1 unit Round Visotube Ø 17,5 mm - clear 10 units * Goblet with 12 colored visotubes and 1 white lid cover Triangular visotubes - for mounting the Daisy goblet. 11 different colors, packed in bags of 10 units. Color Brown Black Red Green Blue Grey Purple Yellow Pink Orange Pistatio Ref info@.com 41

42 Brady BMP label printers The BMP51 is a new printer with a standard keyboard and an extra-large and bright clear display that is easy to read. The entire label is visible on the display making it easy to adjust the layout. The design of the cartridge has been improved and issues with stuck labels and ripped ink ribbons no longer exist. The printer can easily be used as a stand-alone printer. If connected to a PC, labels can be designed by using the LabelMark software. The BMP53 is the same printer as BMP51 but can only be used when connected to a computer. If connected to a PC, labels can be designed by using the LabelMark software. However the printer comes with a Windows driver making it possible to print from other software and patient database systems. The LabelMark Pro labeling software lets you easily design, edit and print labels. The program is very intuitive and useful functions like serializing, multi-print and barcoading are easily done. Ref Product BMP51 label printer EU BMP53 label printer EU LabelMark 5 pro (software) Labels for BMP51 & 53 printer Ref Product Material Type A* B* C* QTY Cryo straw label M49427 I 25,4 25,4 9, labels Cryo straw label - short M I 25,4 19,05 9, labels Cryo label for CBS ID stick M III 27,6 6, labels Transparent dish label M17432 III 25,40 12, labels White dish label M81488 III 48,26 6, labels White dish label M17351 III 25,4 12,7-360 labels Slide label, solvent resistant M97488 III 22,86 22, labels FreezerBonz label M III 41,91 12, labels *measurements in mm CryoPen The Nunc CryoPen is designed for marking plastic and paper products preserved at ultra low temperatures CryoPen - 4 colors 4 units CryoPen - Black 10 units info@.com

43 Clear and reliable identification Standard and reverse mirror printing Easy to mark even thin cryo straws A A TEXT C B TEXT B Type I Type II C B A TEXT Type III LabXpert labels Ref Product Material Type A* B* C* QTY Cryo straw label XSL I 25,4 25,4 9, labels Cryo straw label - short XSL I 25,4 19,05 9, labels HS straw ID stick label X III 27,6 6, labels Cryo vial label XSL I 25,4 63,5 19, labels Cryo vial label XSL II 15,24 66,68 25,4 150 labels Cryo vial label - short XSL II 15,24 45,72 25,4 225 labels Cryo vial label - wide short XSL I 25,40 44,45 25,4 225 labels FreezerBonz label X III 41,91 12,7-225 labels Transparent dish label X III 25,40 12, labels White dish label X III 48,26 6, labels Slide label, solvent resistant X III 22,86 22, labels *measurements in mm Brady TLS2200 labels and printer The TLS2200 printer is very robust printer with a numeric keyboard to be used as a stand-alone printer. The printer is very durable; it is recommended to change the rechargeable battery to an AC adaptor if the printer is always used in the same place. Ref Product TLS2200 label printer Spare battery TLS AC Adapter TLS2200 Ref Product Material Type A* B* C* QTY Cryo straw label PTL I 25,4 25,4 9, labels Cryo straw label - short PTL I 38,1 25,4 9, labels Cryo vial label PTL I 25,4 63,5 19, labels Cryo vial label PTL I 15,24 66,68 25,4 150 labels Freezerbronz label PTL III 48,26 25,4-250 labels Ink cartridge R /box Spare battery TLS /box AC Adapter TLS /box *measurements in mm info@.com 43

44 DualFlex micromanipulation table For ergonomically correct work positions The DualFlex micromanipulation table gives you individually adjustable and ergonomically correct micromanipulation work positions. The center platform for the microscope is height adjustable to ensure ergonomically correct positioning of the microscope during micromanipulation. It is made of polished granite and is wall mounted separately from the two side tables. The two side table plates are syncronically height adjustable to ensure ergonomically correct positioning of manipulators, injectors and joy sticks during micromanipulation. Ref Product DualFlex micromanipulation table Anti-vibration platform Aluminium platform with three pneumatic vibration isolators with rolling diaphragm to give isolation from surface borne vibrations in all directions. Simple to use, just inflate and leave alone. Ref Product Antivibration platform IVF centrifuge The IVF centrifuge 5702 is an economical and reliable centrifuge for the IVF lab. It is very quiet in operation, the design is compact and it requires little space. Two different swing-bucket rotors are available: - a classic 4 round bucket of 2 tubes solution - a simple 2 flat bucket of 4 tubes solution 4 bucket rotor IVF centrifuge 5702 (no rotor) 1 unit Swing-bucket rotor with 4 buckets 1 unit Bucket adaptor for 2 tubes (11 & 15 ml) 2 units Swing-bucket rotor for 2 x 4 tubes (11 &15 ml) 1 unit Adaptors for V tubes (for Ref 74110) 8 units 2 bucket rotor info@.com

45 LivingCell temperature indicators and ThermoCoins The LivingCell temperature indicator is a perfect tool for verifying the temperature of your culture dishes. The ThermoCoin enables you to maintain the temperature of your dishes on the heated surfaces, and they considerably improve the temperature recovery of your dishes. Ref Product Description LCThermometer - LCT01 Ø 32 mm liquid crystal temp. indicator ThermoCoin TC - 35 Ø 32 mm for 35 mm dishes ThermoCoin TC Ø 45 mm ICSI & center-well dishes ThermoCoin TC - 60 Ø 50 mm for 60 mm dishes LCThermometer MiniTube warming plates Laboratory warming plates used for maintaining the temperature of samples at 37 C in IVF. Ref Product Warming plate 18x18 cm w/ internal control unit Warming plate 47x26 cm - thin excl. control unit Warming plate 60x40 cm - thin excl. control unit Control unit, HT-50S (for & 70110) UniHeat table plates Custom-made table plate with a liquid based heating system. The heat uniformity is unique and the heating system is silent. There is minimal vibration effects and it is completely integrated into the table plate. Height-adjustable support stands A height adjustable support stand for laminar flow cabinets. The perfect upgrade to prevent headaches and back/shoulder problems. Can easily be installed as an upgrade to your cabinet. Ref Product UniHeat table plate 120 cm - single UniHeat table plate 180 cm single UniHeat table plate 180 cm double ErgoStand 4 - for 120 cm cabinets ErgoStand 5 - for 150 cm cabinets ErgoStand 6 - for 180 cm cabinets info@.com 45

46 The IVF Workstation of the next generation A light and pleasant workplace The white HI-MACS table plate makes the workspace light and very pleasant Popular options: Ergonomic work positions Height-adjustable support stand You can work standing or sitting The most quiet cabinet on the market Low noise level - < 51 db(a) Sounds like it is not on Heated microscope glass Adjustable light intensity Turn down the light when manipulating cells and turn up when cleaning the cabinet Complete temperature control Individual control of heated surfaces You only heat where you need to work Pass-through tunnel Ref Product IVFTech workstation 120 cm - for 1 microscope IVFTech workstation 150 cm for 1 microscope IVFTech workstation 180 cm for 1 / 2 microscopes Carbon pre-filter info@.com

47 Ergonomic chairs stools Designed for clinical and laboratory use A series of elegant and comfortable saddleback stools and chairs, specially designed for health care, laboratory and clinical use. Equipped with gas operated springs with fine adjustment of backrest angle, seat angle, and seat height. The Jolly Saddle stool is designed with a V-cut saddle front and a cleaved center line that minimizes any annoying pressure. Jolly The Pinto Saddle stool is designed with a thick layer of cold foam, a deep seat indentation and large thigh rests. Pinto w/backrest All chairs, stools and seats are upholstered with Ferrari imitation leather with an antimicrobial and stain resistant finish coating. Available in 8 different colors. The Pilates Air Seat is designed with an air cushion that has the same effect as the famous Pilates ball. The air cushion of the seat constantly makes the body concentrate on sitting, and thereby strengthens your back and lumbar muscles by keeping them active while you work. You will never get the locking feeling from sitting in the same position for too long. Pilates Ref Product Hight Height adjustment Pinto Saddle Stool cm Foot released ring Pinto Saddle Chair w/backrest cm Foot released ring Jolly Saddle Stool cm Foot released ring Jolly Saddle Chair w/backrest cm Foot released ring Pilates Air Seat cm Hand Released Wheels/caster types Ref Product Easy Rolling casters Friction Brake casters Load brake casters Unloaded Brake casters info@.com 47

48 MEA tested IVF disinfectants The Green Line Oosafe Incubator and LAF cabinets An anticorrosive ready-to-use disinfectant for all laboratory equipment, including laminar flow hoods and the insides of incubators. The Blue Line Oosafe floor/laboratory surface An economical (dilution 1:100) surface disinfectant containing a non-ionic soap. Dilute>apply>wait 15 min>rinse and wipe clean. The Orange Line Oosafe Hand A ready-to-use hand disinfectant that will not dry out your skin. Mouse embryos after 72 h incubation in disinfected MINC incubator Study done by: William Lee, Emma Lingham, Dr. Jim Catt, Dr. Sally Catt & Dr. Mulyoto Pangestu Department of Obstetrics and Gynaecology Education Centre of Reproduction and Development MONASH University Australia, 2012 Control Oosafe 6% hydrogen peroxide 70% ethanol Microbial efficacy: Against bacteria, fungus, and viruses...(hepatitis, HIV, influenza and rota virus) Active ingredient:...quarternary ammonium compound No VOC release, no smell, no alcohol MEA-tested and CE-marked Long shelf-life:...three years from manufacturing date,...even after opening Oosafe Incubator disinfectant 1 L Oosafe Incubator disinfectant (refill) 5 L Oosafe disinfectant wipes 70/bucket Oosafe Hand disinfectant 0,5 L Oosafe Hand disinfectant (refill) 5 L Oosafe Surface disinfectant 2 L Oosafe Surface disinfectant (refill) 10 L info@.com