FIFTH ANNUAL SUMMER INTERNSHIP COURSE: DAILY SCHEDULE Jun 11 Jul 27, 2012

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1 DAY DATE TIME FACULTY NAME / OTHER LECTURE TITLE Mon 6/11/12 ORIENTATION 8:00AM 8:30AM BREAKFAST BREAKFAST, Rm. LRI NA5 08 (9:00AM 4:00PM) 8:30AM 11:00AM Internship Checklist: Session 1 Dr. Agarwal/ Dr. Sharma/ Dr. Gupta, LRI / Amphitheater 11:00AM 12:00PM Harry Isaacson, MD Dialogues in Professionalism, Rm. NA5-08/ Amphitheater 12:00PM 1:30PM 1:30PM 2:30PM Internship Checklist: Session 2 Dr. Agarwal/ Dr. Sharma/ Dr. Gupta, LRI / Amphitheater 2:30PM 3:30PM Internship Checklist: Session 3 Overview Dr. Agarwal/ Dr. Sharma/ Dr. Gupta, LRI / Amphitheater of CRM 3:00PM 3:30PM COFFEE BREAK REFRESHMENTS 4:00PM 5:00PM Internship Checklist: Session 4 Dr. Agarwal/ Dr. Sharma/ Dr. Gupta, LRI / Amphitheater Tue 6/12/12 ORIENTATION/ LECTURES 9:00AM 12:00AM Interns Appointment Interns Orientation in Lerner Research Institute, Rm. NA :00PM 1:00PM Lunch PRESENTATION BY INTERNSHIP S: DISCUSSION OF BENCH AND SCIENTIFIC WRITING PROJECTS DIET, MALNUTRITION AND NUTRIENT DEFICIENCIES: EFFECT ON MALE FERTILITY, Rm NA1-138 Stefan du Plessis, HEAT STRESS IN MALE INFERTILITY: RELATIONSHIP WITH OCCUPATION, SEDENTARY LIFESTYLE AND CLOTHING, Rm NA1-138 PhD EFFECT OF SMOKING ON MALE INFERTILITY, Rm NA1-138 Tygerberg, South Africa 1:00 PM 2:00PM Tue, OXIDATIVE PHOSPHORYLATION VS. GLYCOLYSIS: WHAT FUEL DOES Videoconference - 6/12/2012 SPERM USE?, Rm NA1-138 : Ely James, Media IMPACT OF DIABETES MELLITUS ON MALE SEXUAL FUNCTION AND INFERTILITY, Rm NA1-138 PROTEOMIC ANALYSIS OF DIFFERENTIAL PROTEIN EXPRESSION IN MATURE AND IMMATURE SPERMATOZOA, Rm NA :00PM 5:00PM Student & Staff Introduction Student Mixer, Rm. NA1 138, COFFEE/ REFRESHMENT BREAK 3:00PM Wed 6/13/12 LECTURES 8:30AM 9:30AM Stefan Du Plessis, PhD Introduction to Male Reproductive System, Rm. TT :30AM 10:30AM Karen Baker, MD Overview of Male Infertility: Etiology, Diagnosis and Treatment, Rm. TT :00PM 12:30PM Appointment for Portrait Pictures: Alexander Antel, Ali Azeem, Nicole Bevilacqua, Kelly Biedenharn, Drew Bunker, Molly Carnahan, Maria DeLeonibus, Jennifer Fedor, Rm. NA1 127; Tel: (216) :00PM 2:00PM Gretchen Hallerberg, MS Library Resources, Rm. TT :00PM 3:30PM Amy Moore, BA Lecture 1: Ethical Issues in Publication: Authorship and Plagiarism, Rm. TT :00PM 5:00PM Sajal Gupta, MD Introduction to Female Reproductive System, Rm. TT1 102 Thu 6/14/12 LECTURES 8:00AM 8:30AM BREAKFAST BREAKFAST, Rm. NA5-03 James Young, MD Cleveland Clinic Model of Practice in the 21 st Century, Rm. NA5-03 9:15 AM 11:15AM Amy Moore, BA Lecture 2: Writing an Informative and Concise, yet Interesting Title, Abstract and Introduction Appointment for Portrait Pictures:Omar Haque, Raj Kumar, Janet Lanman, George 11:15PM 12:30PM Managadze, Evelina Manvelyan, Rebecca Rossener, Kristina Solvik, Rm. NA1 127; Tel: (216) :30PM 1:30PM Sgt. Ralph Russo Safety Issues on the Campus, Rm.NA5 03 PRESENTATION BY INTERNSHIP S: DISCUSSION OF BENCH AND SCIENTIFIC WRITING PROJECTS Doris Baker, PhD Lexington, KY STATUS OF THE HUMAN EMBRYO: PERSONHOOD, Rm NA5-03 GENE EXPRESSION IN EMBRYOS CREATED BY ASSISTED REPRODUCTIVE 2:00PM 3:00 PM Thu, TECHNOLOGY, Rm NA /14/2012 ASSESSING THE INTER-, INTRA- OBSERVER AND LONGITUDINAL VARIABILITY IN ROUTINE AND ADVANCED SEMEN PARAMETERS, Rm NA5-03 3:00PM 4:00PM Abhishek Deshpande, MD Introduction to Medical Statistics Clinical Case Reviews, Rm. NA5 03 4:00PM 5:00PM Gretchen Hallerberg, MS Library Resources, Rm. NA5 03 1

2 Fri 6/15/12 LECTURES 8:00AM 8:30AM BREAKFAST BREAKFAST, Rm.NA5-03 Rakesh Sharma, PhD Cleveland Clinic AGEING AND REPRODUCTIVE HEALTH, Rm. NA5-03 AGING SPERMATOZOA AND MALE INFERTILTYRm. NA5-03 SPINDLE AND CHROMOSOMAL ALTERATIONS IN METAPHASE II OOCYTE, SPERMATOGENESIS, Rm. NA5-03 EVALUATION OF SEMEN QUALITY FOLLOWING PREPARATION OF HUMAN SEMEN SPECIMENS FOR ART: A CONTROLLED TRIAL,Rm. NA5-03 Sajal Gupta, MD Cleveland Clinic OVARIAN ENDOMETRIOMA: EFFECTS ON ART OUTCOME, Rm. NA5-03 ENDOMETRIOSIS AND OVARIAN CARCINOMA: UNDERSTANDING THE LIFE STYLE FACTORS AND OXIDATIVE STRESS IN FEMALE 9:30AM 10:30AM Fri, COMPARATIVE DYNAMICS OF CRYOPRESERVATION - INDUCED SPERM 6/15/2012 DNA DAMAGE BETWEEN SEMEN SAMPLES COLLECTED ONSITE VERSUS SAMPLES REMOTELY COLLECTED AND SHIPPED, Rm. NA5-03 Appointment for Portrait Pictures: Ethan Vargo, Joseph Vitale, Yiran Zhang, Weijia 10:30AM 12:30AM Jade Zheng, Dr. Doris Baker, Dr. Stefan du Plessis, Rm. NA1 127; Phone: (216) :30 PM 1:30 PM Jennie E. Minnich, MS Research Compliance Issues, Rm. NA5-03 1:30PM 2:30PM Edmund Sabanegh, MD Advances in Microsurgical Techniques in Male Infertility, Rm. NA5-03 2:30PM 3:00PM COFFEE BREAK COFFEE BREAK & REFRESHMENT Alex C Varghese, PhD Montreal, Canada 3:00PM 3:40PM NOVEL STRATEGIES AND BIOLOGICAL FOUNDATIONS FOR SELECTING HUMAN GAMETES AND EMBRYOS IN ASSISTED CONCEPTION TECHNOLOGIES, Rm. NA5-03 SOCIAL EGG FREEZING- CURRENT AND FUTURE PERSPECTIVE, Rm. NA5-03 FERTILITY PRESERVATION IN CANCER PATIENTS: CRYOBIOLOGICAL ADVANCES, Rm. NA5-03 Luiz Carvalho, MD Boston, MA 3:40PM 4:20PM FROM CONCEPTION TO BIRTH: HOW ENDOMETRIOSIS AFFECTS EACH STAGE OF LIFE DEVELOPMENT, Rm. NA5-03 OVARIAN ENDOMETRIOMA AND IN VITRO FERTILIZATION: IS LAPAROSCOPIC SURGERY HARMFUL?, Rm. NA5-03 SURGERY FOR DEEP INFILTRATIVE ENDOMETRIOSIS INCREASES THE ODDS OF IN VITRO FERTILIZATION: WHAT IS THE EVIDENCE?, Rm. NA5-03 Jashoman Banerjee, MD Detroit, MI 4:20PM 5:00PM ROLE OF ENDOMETRIUM IN IVF SUCCESS, Rm. NA5-03 SIGNIFICANCE OF OVARIAN STEM CELLS IN FERTILITY PRESERVATION, Rm. NA5-03 OOCYTE QUALITY- FACTORS AFFECTING, METHODS OF ASSESSMENT, ROLE OF OXIDATIVE STRESS AND ANTIOXIDANTS, Rm. NA5-03 Mon 6/18/12 LECTURES 8:00AM 8:30AM BREAKFAST BREAKFAST, Rm.TT1 104 William Hurd, MD Infertility Diagnosis and Treatment: The Basics, Rm. TT :30AM 10:30AM Holly Thacker, MD Menopause and Women's Health, Rm. TT :00AM 12:00AM Margaret McKenzie, MD Sexually Transmitted Infections, Rm. TT :30PM 01:30PM 1:30PM 2:15PM Sajal Gupta, MD Introduction to Endometriosis, Rm. TT :30PM 3:15PM Amani Shaman, MD Pathophysiology and Treatment of PCOS, LRI Rm. TT :30PM 4:30PM Doris Baker, PhD Overview of Assisted Reproduction: A Historical Perspective, Rm. TT :30PM 5:15PM Rakesh Sharma, PhD Safety Guidelines in Reproductive Research Lab, Rm. TT

3 Tue 6/19/12 LECTURES Stefan Du Plessis, PhD Physiological Role of Reactive Oxygen Species in Sperm Function, Rm. TT :30AM 10:30AM Rakesh Sharma, PhD Pathological Role of Reactive Oxygen Species in Male Infertility, Rm. TT :00AM 12:00PM Amani Shaman, MD Impact of Oxidative Stress in Female Reproduction Rm. TT :00AM 1:00PM 1:00PM 2:30PM Amy Moore, BA Lecture 3: The Resources Available to Help Authors Write, Rm. TT :00PM 4:00PM Eric Klein, MD Introduction to Glickman Urological and Kidney Institute, Rm. TT :00PM 5:00PM Doris Baker, PhD Cryopreservation and its Role in Assisted Reproduction Rm. TT1 100 Wed 6/20/12 RESEARCH DAY BREAKFAST Rm. TT3 06, 09, 10 9:00AM 5:00PM RESEARCH DAY Rm. TT3 06, 09, 10 Thu 6/21/12 RESEARCH DAY Campinas, Brazil Sandro Esteves, MD, PhD, Campinas, Brazil Sperm Retrieval Techniques: Looking for a Needle in the Haystack, Rm. NA Media Service : Ely James (216) :15AM 5:00PM RESEARCH DAY RESEARCH DAY, Rm. TT3 06, 09, 10 Fri 6/22/12 RESEARCH DAY 8:00AM 9:30AM BREAKFAST RESEARCH UPDATE MEETING (MANDATORY), Rm. TT :30AM 5:00PM RESEARCH DAY RESEARCH DAY, Rm. TT3 06, 09, 10 Mon 6/25/12 LECTURES 8:00AM 8:30AM BREAKFAST BREAKFAST, Rm. TT :30AM 9:30AM Stefan Du Plessis, PhD Role of Proteomics in Male Infertility, Rm. TT :30AM 10:30AM Anthony J. Thomas Jr. MD Bioethics of ART, Rm. TT :45AM 11:45AM Ardeshir B Mehr, PhD Finger Printing and Ancestral Tracing in Molecular Genetics, Rm. TT :00AM 1:00PM Maria Siemionow, MD Face Transplant Surgery: Recent Advances, Rm. TT :00PM 2:00PM 2:00PM 3:00PM Sajal Gupta, MD Fertilization and Embryonic Development, LRI Rm. TT :00PM 4:00PM Karen Baker, MD Genetic Aspects of Male Infertility, Rm. TT :00PM 5:00PM Doris Baker, PhD Advanced ART Procedures and Embryo and Gamete Donation, Rm. TT1 100 Tue 6/26/12 LECTURES Tommaso Falcone, MD Seminars on Female Infertility, Source: Clinical Reproductive Medicine and Surgery, Editors: Hurd and Falcone, Rm. A :30AM 10:30AM Enrique Soto, MD Ovarian Stimulation Protocols An update, Rm. A :00AM 12:00PM Amy Moore, BA Lecture 4: Writing Process, Rm. A :00AM 1:30 PM 1:30PM 2:30PM Ibraheem Al Aref, MD Endometriosis Disease and its Relatonship with Oxidative Stress and DNA Damage, Rm. A :00PM 4:00PM Rakesh Sharma, PhD Laboratory Evaluation of Infertile Men Review of Routine and Advanced Techniques, Rm. Q :00PM 5:00PM Ashok Agarwal, PhD Fertility Preservation in Male Cancer Patients Recent Advances, Rm. Q1-203 Wed 6/27/12 RESEARCH DAY Thu 6/28/12 RESEARCH DAY Fri 6/29/12 RESEARCH DAY BREAKFAST RESEARCH UPDATE MEETING (MANDATORY), Rm. TT1 104 Mon 7/2/12 LECTURES BREAKFAST BREAKFAST, A8 800 Tommaso Falcone, MD Endometriosis: Etiology and Management, LRI Rm. A :30AM 10:15AM Manjula Gupta, PhD Hormone Regulation: Laboratory Assays, LRI Rm. A :30AM 5:00PM RESEARCH DAY RESEARCH DAY, Rm. TT3 06, 09, 10 Tue 7/3/12 RESEARCH DAY Manjula Gupta, PhD Immunoassays: Laboratory Cases; Curves and Sinkers, Rm. TT :30AM 5:00PM RESEARCH DAY RESEARCH DAY, Rm. TT3 06, 09, 10 Thu 7/5/12 Research Day Fri 7/6/12 RESEARCH DAY BREAKFAST RESEARCH UPDATE MEETING (MANDATORY), Rm. TT1 104 Mon 7/9/12 Research Day BREAKFAST BREAKFAST 3

4 Tue 7/10/12 LECTURES Sylvia Morrison, BA Public Speaking Lecture Series 1, Rm. Q1 203 Wed 7/11/12 RESEARCH DAY 8:00AM 8:30AM BREAKFAST BREAKFAST, NA :30AM 11:15AM Stephen Jones, MD Innovative Treatments for Prostate Cancer, Rm. NA :30AM 2:30PM RESEARCH DAY RESEARCH DAY, Rm. TT3 06, 09, 10 2:30PM 3:30PM Lab Picture Shoot Rm. TT3 06 and TT3 07 3:30PM 5:00PM RESEARCH DAY RESEARCH DAY, Rm. TT3 06, 09, 10 Thu 7/12/12 FEMALE INFERTILITY MINI-SUMMIT FEMALE INFERTILITY MINI-SUMMIT 7:30AM 8:00AM BREAKFAST BREAKFAST, Rm. NA5 03 Botros Peter Rizk, MD Initial Assessment of Female, LRI Rm. NA5 24 9:30AM 10:30PM Botros Peter Rizk, MD Pathophysiology and Treatment of PCOS, LRI Rm. NA5 24 Botroz Peter Rizk, 11:00AM 12:00PM Botros Peter Rizk, MD Ultrasound in Infertility, Rm. NA5 24 MD, PhD Mobile, 12:30PM 01:30PM BOXED LUNCH AL 1:30PM 2:30PM Botros Peter Rizk, MD Endometriosis Associated Infertility, Rm. NA5 24 3:00PM 3:30PM Botros Peter Rizk, MD Sonohysterography, Rm. NA5 24 3:30PM 4:00PM COFFEE BREAK COFFEE BREAK, Rm. NA5-24 4:00PM 5:00PM Botros Peter Rizk, MD Fallopian Tube Catheterization and Tubal Surgery, Rm. NA5 24 Fri 7/13/12 FEMALE INFERTILITY MINI-SUMMIT FEMALE INFERTILITY MINI-SUMMIT 7:50AM 8:30AM Group Picture Location: In front of Crile Building Botroz Peter Rizk, MD, PhD Mobile, AL 8:30AM 9:00AM BREAKFAST BREAKFAST, Rm. NA5 03 9:00AM 11:30AM Presentation by Interns Short PPT Presentations (5 min talk + 2 min ), Rm. NA :30AM 12:30PM Tommaso Falcone, MD Role of Surgical Robotics in Reproductive Medicine, Rm. NA :30 1:00PM 1:00PM 2:00PM Botros Peter Rizk, MD Assisted Reproduction Techniques, Rm. NA5 03 2:30AM 3:30PM Botros Peter Rizk, MD Medical Management of Endometriosis Associated Pain, Rm. NA5 03 4:00 5:00PM Botros Peter Rizk, MD Ovarian Hyperstimulation Rm. NA5 03 Sat 7/14/12 RECEPTION RECEPTION Get Together at Agarwal Reception at Agarwal Residence (130 West Juniper Lane, 6:30PM 11:00PM Residence Moreland Hills, OH, 44022) Mon 7/16/12 LECTURES 8:00AM 8:30AM BREAKFAST BREAKFAST, Rm. TT1 104 Karl Drogo Montague, MD Management of Erectile Dysfunction 2011: How Did We Get Here?, Rm. TT :00 AM 10:00AM TBD TBD, Rm TT :00 AM 12:00PM Sylvia Morrison, BA Public Speaking Lecture Series 2, Rm. TT :00 1:00PM 1:00 PM 1:45PM Margaret McKenzie, MD Contraception, Rm. TT :00PM 2:45PM Satya Yadav, PhD An Introduction to Molecular Biotechnology, Rm. TT :00 PM 4:00PM Robert Stein, MD Robotic Surgery: Principles, Advantages and Outcomes, Rm. TT :00 PM 5:00PM Adi Mehta, MD Metabolic Complications of Pregnancy, Rm. TT1 104 Tue 7/17/12 LECTURES Charles Modlin, MD Kidney Transplantation: Indications, Patient preperation, Operative technique and Postoperative Care, Rm. TT :30AM 10:30AM Alan Lichtin, MD Role of Institutional Review Board (IRB) in Research, Rm. TT :00AM 12:00PM Stefan Du Plessis, PhD The Effects of Obesity on Male Reproduction, Rm. TT :00PM 1:00 PM 1:00PM 2:00PM Julierut Tantibhedhyangkul, MD PCOS, Rm. TT :00PM 3:00 PM Gayatri Mohanty, MS Sperm Chromatin Damage and Relationship with Male Infertility, Rm. TT :00PM 4:00 PM Luay Susan, MD Prostatitis and Male Infertility TT :00PM 5:00 PM Ali Ahmady, PhD An Introduction to ICSI, IMSI and PICSI, Rm. TT1-100 Wed 7/18/12 Research Day Thu 7/19/12 Research Day 8:00AM 3:00PM RESEARCH DAY RESEARCH DAY, Rm. TT3 06, 09, 10 3:00PM 5:00PM Kathleen Franco, MD Introduction and Tour of Lerner College of Medicine, Rm. NA5-24 Fri 7/20/12 Research Day BREAKFAST RESEARCH UPDATE MEETING (MANDATORY), Rm. TT1 104 Mon 7/23/12 Research Day Tue 7/24/12 Research Day 4

5 Wed 7/25/12 Research Day 8:00AM 5:00PM Wrap Up Day Complete and submit Exit Checklist, Rm. TT3 06, 09, 10 Thu 7/26/12 LECTURES 8:00AM 8:30AM BREAKFAST Breakfast, Rm. NA5 24 9:00AM 10:00AM 10:00AM 11:00AM Sijo Parekattil, MD Winter Haven, FL Luiz Carvalho, MD, PhD Boston, MA A Novel Structured Treatment Algorithm Incorporating Robotic Microsurgery for Men with Chronic Orchialgia/groin Pain, Rm. NA5 24 Media Service : Ely James (216) IVF Treatment in Patients with Endometriosis - A Challenging Approach, Rm. NA :00AM 5:00PM Wrap Up Day MUST Submit Exit Checklist, Rm. TT3 06, 09, 10 Fri 7/27/12 7:30AM 8:00AM BREAKFAST BREAKFAST, Rm. NA5-08 8:00AM 10:30PM Scientific Presentations Scientific Presentations by Interns (10 minutes each w/ 5 minutes Q&A), LRI 10:30AM 10:45AM COFFEE BREAK REFRESHMENT, Rm. NA :00AM 1:00PM Scientific Presentations Scientific Presentations by Interns (10 minutes each w/ 5 minutes Q&A), LRI 1:00PM 1:45PM BOXED LUNCH 1:45PM 2:30PM Scientific Presentations Scientific Presentations by Interns ((10 minutes each w/ 5 minutes Q&A), LRI 2:30PM 3:00PM COFFEE BREAK COFFEE BREAK & REFRESHMENT 2:30PM 4:00PM Scientific Presentations Scientific Presentations by Interns ((10 minutes each w/ 5 minutes Q&A), LRI 6:00PM 6:30PM Hors d'oeuvre Six Continent Room, Intercontinental Hotel and Conference Center, 9801 Carnegie Avenue, Cleveland, OH 44106, Phone (216) :30PM 7:00PM Peter Nagy, MD, PhD Discovery That Changed The World of Reproduction: Oocyte Atlanta, GA Cryopreservation, Intercontinental Hotel and Conference Center 7:00PM 11:00PM AWARD CEREMONY DINNER, Intercontinental Hotel and Conference Center Note: Laptop needed in Q1-203, TT1 and NA1 buildings. Contact Media Services for help with A/V at

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